-
1
-
-
70149086262
-
Protein arginine deiminase 4 (PAD4): Current understanding and future therapeutic potential
-
Jones, J. E., Causey, C. P., Knuckley, B., Slack-Noyes, J. L., and Thompson, P. R. (2009) Protein arginine deiminase 4 (PAD4): Current understanding and future therapeutic potential Curr. Opin. Drug Discovery Dev. 12, 616-627
-
(2009)
Curr. Opin. Drug Discovery Dev.
, vol.12
, pp. 616-627
-
-
Jones, J.E.1
Causey, C.P.2
Knuckley, B.3
Slack-Noyes, J.L.4
Thompson, P.R.5
-
2
-
-
33751001725
-
Histone citrullination by protein arginine deiminase: Is arginine methylation a green light or a roadblock?
-
Thompson, P. R. and Fast, W. (2006) Histone citrullination by protein arginine deiminase: Is arginine methylation a green light or a roadblock? ACS Chem. Biol. 1, 433-441
-
(2006)
ACS Chem. Biol.
, vol.1
, pp. 433-441
-
-
Thompson, P.R.1
Fast, W.2
-
3
-
-
2942555614
-
Citrullinated proteins: Sparks that may ignite the fire in rheumatoid arthritis
-
Vossenaar, E. R. and Van Venrooij, W. J. (2004) Citrullinated proteins: sparks that may ignite the fire in rheumatoid arthritis Arthritis Res. Ther. 6, 107-111 (Pubitemid 38735665)
-
(2004)
Arthritis Research and Therapy
, vol.6
, Issue.3
, pp. 107-111
-
-
Vossenaar, E.R.1
Van Venrooij, W.J.2
-
4
-
-
0242720407
-
PAD, a growing family of citrullinating enzymes: Genes, features and involvement in disease
-
DOI 10.1002/bies.10357
-
Vossenaar, E. R., Zendman, A. J., van Venrooij, W. J., and Pruijn, G. J. (2003) PAD, a growing family of citrullinating enzymes: genes, features and involvement in disease Bioessays 25, 1106-1118 (Pubitemid 37411770)
-
(2003)
BioEssays
, vol.25
, Issue.11
, pp. 1106-1118
-
-
Vossenaar, E.R.1
Zendman, A.J.W.2
Van Venrooij, W.J.3
Pruijn, G.J.M.4
-
5
-
-
0037147140
-
Nuclear localization of peptidylarginine deiminase V and histone deimination in granulocytes
-
DOI 10.1074/jbc.M208795200
-
Nakashima, K., Hagiwara, T., and Yamada, M. (2002) Nuclear localization of peptidylarginine deiminase V and histone deimination in granulocytes J. Biol. Chem. 277, 49562-49568 (Pubitemid 36014395)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.51
, pp. 49562-49568
-
-
Nakashima, K.1
Hagiwara, T.2
Yamada, M.3
-
6
-
-
0036295234
-
Deimination of arginine residues in nucleophosmin/B23 and histones in HL-60 granulocytes
-
DOI 10.1006/bbrc.2001.6303
-
Hagiwara, T., Nakashima, K., Hirano, H., Senshu, T., and Yamada, M. (2002) Deimination of arginine residues in nucleophosmin/B23 and histones in HL-60 granulocytes Biochem. Biophys. Res. Commun. 290, 979-983 (Pubitemid 34687458)
-
(2002)
Biochemical and Biophysical Research Communications
, vol.290
, Issue.3
, pp. 979-983
-
-
Hagiwara, T.1
Nakashima, K.2
Hirano, H.3
Senshu, T.4
Yamada, M.5
-
7
-
-
0033600723
-
Molecular characterization of peptidylarginine deiminase in HL-60 cells induced by retinoic acid and 1alpha,25-dihydroxyvitamin D(3)
-
Nakashima, K., Hagiwara, T., Ishigami, A., Nagata, S., Asaga, H., Kuramoto, M., Senshu, T., and Yamada, M. (1999) Molecular characterization of peptidylarginine deiminase in HL-60 cells induced by retinoic acid and 1alpha,25-dihydroxyvitamin D(3) J. Biol. Chem. 274, 27786-27792
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 27786-27792
-
-
Nakashima, K.1
Hagiwara, T.2
Ishigami, A.3
Nagata, S.4
Asaga, H.5
Kuramoto, M.6
Senshu, T.7
Yamada, M.8
-
8
-
-
47949123469
-
Regulation of p53 target gene expression by peptidylarginine deiminase 4
-
Li, P., Yao, H., Zhang, Z., Li, M., Luo, Y., Thompson, P. R., Gilmour, D. S., and Wang, Y. (2008) Regulation of p53 target gene expression by peptidylarginine deiminase 4 Mol. Cell. Biol. 28, 4745-4758
-
(2008)
Mol. Cell. Biol.
, vol.28
, pp. 4745-4758
-
-
Li, P.1
Yao, H.2
Zhang, Z.3
Li, M.4
Luo, Y.5
Thompson, P.R.6
Gilmour, D.S.7
Wang, Y.8
-
9
-
-
4444372638
-
Histone deimination antagonizes arginine methylation
-
DOI 10.1016/j.cell.2004.08.020, PII S0092867404007998
-
Cuthbert, G. L., Daujat, S., Snowden, A. W., Erdjument-Bromage, H., Hagiwara, T., Yamada, M., Schneider, R., Gregory, P. D., Tempst, P., Bannister, A. J., and Kouzarides, T. (2004) Histone deimination antagonizes arginine methylation Cell 118, 545-553 (Pubitemid 39179708)
-
(2004)
Cell
, vol.118
, Issue.5
, pp. 545-553
-
-
Cuthbert, G.L.1
Daujat, S.2
Snowden, A.W.3
Erdjument-Bromage, H.4
Hagiwara, T.5
Yamada, M.6
Schneider, R.7
Gregory, P.D.8
Tempst, P.9
Bannister, A.J.10
Kouzarides, T.11
-
10
-
-
5044228483
-
Human PAD4 regulates histone arginine methylation levels via demethylimination
-
DOI 10.1126/science.1101400
-
Wang, Y., Wysocka, J., Sayegh, J., Lee, Y. H., Perlin, J. R., Leonelli, L., Sonbuchner, L. S., McDonald, C. H., Cook, R. G., Dou, Y., Roeder, R. G., Clarke, S., Stallcup, M. R., Allis, C. D., and Coonrod, S. A. (2004) Human PAD4 regulates histone arginine methylation levels via demethylimination Science 306, 279-283 (Pubitemid 39336873)
-
(2004)
Science
, vol.306
, Issue.5694
, pp. 279-283
-
-
Wang, Y.1
Wysocka, J.2
Sayegh, J.3
Lee, Y.-H.4
Pertin, J.R.5
Leonelli, L.6
Sonbuchner, L.S.7
McDonald, C.H.8
Cook, R.G.9
Dou, Y.10
Roeder, R.G.11
Clarke, S.12
Stallcup, M.R.13
Allis, C.D.14
Coonrod, S.A.15
-
11
-
-
17144363594
-
Deimination of histone H2A and H4 at arginine 3 in HL-60 granulocytes
-
DOI 10.1021/bi047505c
-
Hagiwara, T., Hidaka, Y., and Yamada, M. (2005) Deimination of histone H2A and H4 at arginine 3 in HL-60 granulocytes Biochemistry 44, 5827-5834 (Pubitemid 40525119)
-
(2005)
Biochemistry
, vol.44
, Issue.15
, pp. 5827-5834
-
-
Hagiwara, T.1
Hidaka, Y.2
Yamada, M.3
-
12
-
-
3543004695
-
2+-induced activation of human PAD4
-
DOI 10.1038/nsmb799
-
2+-induced activation of human PAD4 Nat. Struct. Mol. Biol. 11, 777-783 (Pubitemid 39014504)
-
(2004)
Nature Structural and Molecular Biology
, vol.11
, Issue.8
, pp. 777-783
-
-
Arita, K.1
Hashimoto, H.2
Shimizu, T.3
Nakashima, K.4
Yamada, M.5
Sato, M.6
-
13
-
-
23244447251
-
Kinetic characterization of protein arginine deiminase 4: A transcriptional corepressor implicated in the onset and progression of rheumatoid arthritis
-
DOI 10.1021/bi050292m
-
Kearney, P. L., Bhatia, M., Jones, N. G., Luo, Y., Glascock, M. C., Catchings, K. L., Yamada, M., and Thompson, P. R. (2005) Kinetic characterization of protein arginine deiminase 4: A transcriptional corepressor implicated in the onset and progression of rheumatoid arthritis Biochemistry 44, 10570-10582 (Pubitemid 41098234)
-
(2005)
Biochemistry
, vol.44
, Issue.31
, pp. 10570-10582
-
-
Kearney, P.L.1
Bhatia, M.2
Jones, N.G.3
Yuan, L.4
Glascock, M.C.5
Catchings, K.L.6
Yamada, M.7
Thompson, P.R.8
-
14
-
-
34249877154
-
Protein arginine deiminase 4: Evidence for a reverse protonation mechanism
-
DOI 10.1021/bi700095s
-
Knuckley, B., Bhatia, M., and Thompson, P. R. (2007) Protein arginine deiminase 4: Evidence for a reverse protonation mechanism Biochemistry 46, 6578-6587 (Pubitemid 46870123)
-
(2007)
Biochemistry
, vol.46
, Issue.22
, pp. 6578-6587
-
-
Knuckley, B.1
Bhatia, M.2
Thompson, P.R.3
-
15
-
-
24344505085
-
The peptidylarginine deiminases expressed in human epidermis differ in their substrate specificities and subcellular locations
-
DOI 10.1007/s00018-005-5196-y
-
Mechin, M. C., Enji, M., Nachat, R., Chavanas, S., Charveron, M., Ishida-Yamamoto, A., Serre, G., Takahara, H., and Simon, M. (2005) The peptidylarginine deiminases expressed in human epidermis differ in their substrate specificities and subcellular locations Cell. Mol. Life Sci. 62, 1984-1995 (Pubitemid 41261845)
-
(2005)
Cellular and Molecular Life Sciences
, vol.62
, Issue.17
, pp. 1984-1995
-
-
Mechin, M.C.1
Enji, M.2
Nachat, R.3
Chavanas, S.4
Charveron, M.5
Ishida-Yamamoto, A.6
Serre, G.7
Takahara, H.8
Simon, M.9
-
16
-
-
19944417554
-
Comparison of enzymatic properties between hPADI2 and hPADI4
-
DOI 10.1016/j.bbrc.2004.11.152, PII S0006291X0402755X
-
Nakayama-Hamada, M., Suzuki, A., Kubota, K., Takazawa, T., Ohsaka, M., Kawaida, R., Ono, M., Kasuya, A., Furukawa, H., Yamada, R., and Yamamoto, K. (2005) Comparison of enzymatic properties between hPADI2 and hPADI4 Biochem. Biophys. Res. Commun. 327, 192-200 (Pubitemid 40051370)
-
(2005)
Biochemical and Biophysical Research Communications
, vol.327
, Issue.1
, pp. 192-200
-
-
Nakayama-Hamada, M.1
Suzuki, A.2
Kubota, K.3
Takazawa, T.4
Ohsaka, M.5
Kawaida, R.6
Ono, M.7
Kasuya, A.8
Furukawa, H.9
Yamada, R.10
Yamamoto, K.11
-
17
-
-
54249134964
-
Kinetics of human peptidylarginine deiminase 2 (hPAD2)-reduction of Ca2+ dependence by phospholipids and assessment of proposed inhibition by paclitaxel side chains
-
Musse, A. A., Polverini, E., Raijmakers, R., and Harauz, G. (2008) Kinetics of human peptidylarginine deiminase 2 (hPAD2)-reduction of Ca2+ dependence by phospholipids and assessment of proposed inhibition by paclitaxel side chains Biochem. Cell Biol. 86, 437-447
-
(2008)
Biochem. Cell Biol.
, vol.86
, pp. 437-447
-
-
Musse, A.A.1
Polverini, E.2
Raijmakers, R.3
Harauz, G.4
-
18
-
-
1942522084
-
Profiling enzyme activities in vivo using click chemistry methods
-
DOI 10.1016/j.chembiol.2004.03.012, PII S1074552104000961
-
Speers, A. E. and Cravatt, B. F. (2004) Profiling enzyme activities in vivo using click chemistry methods Chem. Biol. 11, 535-546 (Pubitemid 38511759)
-
(2004)
Chemistry and Biology
, vol.11
, Issue.4
, pp. 535-546
-
-
Speers, A.E.1
Cravatt, B.F.2
-
19
-
-
1042287130
-
The development and application of methods for activity-based protein profiling
-
DOI 10.1016/j.cbpa.2003.11.004
-
Jessani, N. and Cravatt, B. F. (2004) The development and application of methods for activity-based protein profiling Curr. Opin. Chem. Biol. 8, 54-59 (Pubitemid 38201478)
-
(2004)
Current Opinion in Chemical Biology
, vol.8
, Issue.1
, pp. 54-59
-
-
Jessani, N.1
Cravatt, B.F.2
-
20
-
-
0347087452
-
Chemical Strategies for Activity-Based Proteomics
-
DOI 10.1002/cbic.200300721
-
Speers, A. E. and Cravatt, B. F. (2004) Chemical strategies for activity-based proteomics ChemBioChem 5, 41-47 (Pubitemid 38095018)
-
(2004)
ChemBioChem
, vol.5
, Issue.1
, pp. 41-47
-
-
Speers, A.E.1
Cravatt, B.F.2
-
21
-
-
31944448153
-
A fluoroacetamidine-based inactivator of protein arginine deiminase 4: Design, synthesis, and in vitro and in vivo evaluation
-
DOI 10.1021/ja0576233
-
Luo, Y., Knuckley, B., Lee, Y. H., Stallcup, M. R., and Thompson, P. R. (2006) A fluoro-acetamidine based inactivator of protein arginine deiminase 4 (PAD4): Design, synthesis, and in vitro and in vivo evaluation J. Am. Chem. Soc. 128, 1092-1093 (Pubitemid 43190618)
-
(2006)
Journal of the American Chemical Society
, vol.128
, Issue.4
, pp. 1092-1093
-
-
Luo, Y.1
Knuckley, B.2
Lee, Y.-H.3
Stallcup, M.R.4
Thompson, P.R.5
-
22
-
-
33749359452
-
Inhibitors and inactivators of protein arginine deiminase 4: Functional and structural characterization
-
DOI 10.1021/bi061180d
-
Luo, Y., Arita, K., Bhatia, M., Knuckley, B., Lee, Y. H., Stallcup, M. R., and Thompson, P. R. (2006) Inhibitors and inactivators of protein arginine deiminase 4: Functional and structural characterization Biochemistry 45, 11727-11736 (Pubitemid 44497800)
-
(2006)
Biochemistry
, vol.45
, Issue.39
, pp. 11727-11736
-
-
Luo, Y.1
Arita, K.2
Bhatia, M.3
Knuckley, B.4
Lee, Y.-H.5
Stallcup, M.R.6
Sato, M.7
Thompson, P.R.8
-
23
-
-
27144463085
-
Inactivation of two diverse enzymes in the amidinotransferase superfamily by 2-chloroacetamidine: Dimethylargininase and peptidylarginine deiminase
-
DOI 10.1021/bi051341y
-
Stone, E. M., Schaller, T. H., Bianchi, H., Person, M. D., and Fast, W. (2005) Inactivation of two diverse enzymes in the amidinotransferase superfamily by 2-chloroacetamidine: Dimethylargininase and peptidylarginine deiminase Biochemistry 44, 13744-13752 (Pubitemid 41507455)
-
(2005)
Biochemistry
, vol.44
, Issue.42
, pp. 13744-13752
-
-
Stone, E.M.1
Schaller, T.H.2
Bianchi, H.3
Person, M.D.4
Fast, W.5
-
24
-
-
76649086666
-
Haloacetamidine-based inactivators of protein arginine deiminase 4 (PAD4): Evidence that general acid catalysis promotes efficient inactivation
-
Knuckley, B., Causey, C. P., Pellechia, P. J., Cook, P. F., and Thompson, P. R. (2010) Haloacetamidine-based inactivators of protein arginine deiminase 4 (PAD4): evidence that general acid catalysis promotes efficient inactivation ChemBioChem 11, 161-165
-
(2010)
ChemBioChem
, vol.11
, pp. 161-165
-
-
Knuckley, B.1
Causey, C.P.2
Pellechia, P.J.3
Cook, P.F.4
Thompson, P.R.5
-
25
-
-
34250746414
-
Tandem orthogonal proteolysis-activity-based protein profiling (TOP-ABPP) - A general method for mapping sites of probe modification in proteomes
-
DOI 10.1038/nprot.2007.194, PII NPROT.2007.194
-
Weerapana, E., Speers, A. E., and Cravatt, B. F. (2007) Tandem orthogonal proteolysis-activity-based protein profiling (TOP-ABPP)-a general method for mapping sites of probe modification in proteomes Nat. Protoc. 2, 1414-1425 (Pubitemid 46952321)
-
(2007)
Nature Protocols
, vol.2
, Issue.6
, pp. 1414-1425
-
-
Weerapana, E.1
Speers, A.E.2
Cravatt, B.F.3
-
26
-
-
70350307216
-
A click chemistry mediated in vivo activity probe for dimethylarginine dimethylaminohydrolase
-
Wang, Y., Hu, S., and Fast, W. (2009) A click chemistry mediated in vivo activity probe for dimethylarginine dimethylaminohydrolase J. Am. Chem. Soc. 131, 15096-15097
-
(2009)
J. Am. Chem. Soc.
, vol.131
, pp. 15096-15097
-
-
Wang, Y.1
Hu, S.2
Fast, W.3
-
27
-
-
0037462106
-
Activity-based protein profiling in vivo using a copper(I)-catalyzed azide-alkyne [3 + 2] cycloaddition
-
DOI 10.1021/ja034490h
-
Speers, A. E., Adam, G. C., and Cravatt, B. F. (2003) Activity-based protein profiling in vivo using a copper(i)-catalyzed azide-alkyne [3 + 2] cycloaddition J. Am. Chem. Soc. 125, 4686-4687 (Pubitemid 36505343)
-
(2003)
Journal of the American Chemical Society
, vol.125
, Issue.16
, pp. 4686-4687
-
-
Speers, A.E.1
Adam, G.C.2
Cravatt, B.F.3
-
28
-
-
0037099395
-
A stepwise huisgen cycloaddition process: Copper(I)-catalyzed regioselective 'ligation' of azides and terminal alkynes
-
DOI 10.1002/1521-3773(20020715)41:14<2596::AID-ANIE2596>3.0.CO;2-4
-
Rostovtsev, V. V., Green, L. G., Fokin, V. V., and Sharpless, K. B. (2002) A stepwise huisgen cycloaddition process: copper(I)-catalyzed regioselective "ligation" of azides and terminal alkynes Angew. Chem., Int. Ed. 41, 2596-2599 (Pubitemid 34803480)
-
(2002)
Angewandte Chemie - International Edition
, vol.41
, Issue.14
, pp. 2596-2599
-
-
Rostovtsev, V.V.1
Green, L.G.2
Fokin, V.V.3
Sharpless, K.B.4
-
29
-
-
0037012920
-
Peptidotriazoles on solid phase: [1,2,3]-Triazoles by regiospecific copper(I)-catalyzed 1,3-dipolar cycloadditions of terminal alkynes to azides
-
DOI 10.1021/jo011148j
-
Tornoe, C. W., Christensen, C., and Meldal, M. (2002) Peptidotriazoles on solid phase: [1,2,3]-triazoles by regiospecific copper(i)-catalyzed 1,3-dipolar cycloadditions of terminal alkynes to azides J. Org. Chem. 67, 3057-3064 (Pubitemid 34457265)
-
(2002)
Journal of Organic Chemistry
, vol.67
, Issue.9
, pp. 3057-3064
-
-
Tornoe, C.W.1
Christensen, C.2
Meldal, M.3
-
30
-
-
33751010478
-
Activity-based protein profiling reagents for protein arginine deiminase 4 (PAD4): Synthesis and in vitro evaluation of a fluorescently labeled probe
-
DOI 10.1021/ja0656907
-
Luo, Y., Knuckley, B., Bhatia, M., and Thompson, P. R. (2006) Activity based protein profiling reagents for protein arginine deiminase 4 (PAD4): Synthesis and in vitro evaluation of a fluorescently-labeled probe J. Am. Chem. Soc. 128, 14468-14469 (Pubitemid 44749840)
-
(2006)
Journal of the American Chemical Society
, vol.128
, Issue.45
, pp. 14468-14469
-
-
Luo, Y.1
Knuckley, B.2
Bhatia, M.3
Pellechia, P.J.4
Thompson, P.R.5
-
31
-
-
22244445882
-
A tandem orthogonal proteolysis strategy for high-content chemical proteomics
-
DOI 10.1021/ja0532842
-
Speers, A. E. and Cravatt, B. F. (2005) A tandem orthogonal proteolysis strategy for high-content chemical proteomics J. Am. Chem. Soc. 127, 10018-10019 (Pubitemid 40995443)
-
(2005)
Journal of the American Chemical Society
, vol.127
, Issue.28
, pp. 10018-10019
-
-
Speers, A.E.1
Cravatt, B.F.2
-
32
-
-
79951578893
-
Protein arginine deiminase 4: A target for an epigenetic cancer therapy
-
Slack, J. L., Causey, C. P., and Thompson, P. R. (2010) Protein arginine deiminase 4: a target for an epigenetic cancer therapy Cell. Mol. Life Sci. 68, 709-720
-
(2010)
Cell. Mol. Life Sci.
, vol.68
, pp. 709-720
-
-
Slack, J.L.1
Causey, C.P.2
Thompson, P.R.3
-
33
-
-
70249133329
-
Functional connection between deimination and deacetylation of histones
-
Denis, H., Deplus, R., Putmans, P., Yamada, M., Metivier, R., and Fuks, F. (2009) Functional connection between deimination and deacetylation of histones Mol. Cell. Biol. 29, 4982-4993
-
(2009)
Mol. Cell. Biol.
, vol.29
, pp. 4982-4993
-
-
Denis, H.1
Deplus, R.2
Putmans, P.3
Yamada, M.4
Metivier, R.5
Fuks, F.6
-
34
-
-
68949118945
-
-
6.0 ed., Erithacus Software Limited, Horley, U.K.
-
Leatherbarrow, R. J. (2007) GraFit Version 6, 6.0 ed., Erithacus Software Limited, Horley, U.K.
-
(2007)
GraFit Version 6
-
-
Leatherbarrow, R.J.1
-
35
-
-
34548178909
-
In-gel digestion for mass spectrometric characterization of proteins and proteomes
-
Shevchenko, A., Tomas, H., Havlis, J., Olsen, J. V., and Mann, M. (2006) In-gel digestion for mass spectrometric characterization of proteins and proteomes Nat. Protoc. 1, 2856-2860
-
(2006)
Nat. Protoc.
, vol.1
, pp. 2856-2860
-
-
Shevchenko, A.1
Tomas, H.2
Havlis, J.3
Olsen, J.V.4
Mann, M.5
|