Biochemical and structural studies of uncharacterized protein PA0743 from Pseudomonas aeruginosa revealed NAD +-dependent L-Serine dehydrogenase

Journal of Biological Chemistry

Volumn 287, Issue 3, 2012, Pages 1874-1883

  Tchigvintsev, Anatoli ^a   Singer, Alexander ^a   Brown, Greg ^a   Flick, Robert ^a   Evdokimova, Elena ^a   Tan, Kemin ^b   Gonzalez, Claudio F ^c   Savchenko, Alexei ^a   Yakunin, Alexander F ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b ARGONNE NATIONAL LABORATORY   (United States)

^c UNIVERSITY OF FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYTIC RESIDUE; COFACTORS; ENZYME ACTIVE SITES; FOUR AMINO ACIDS; GLUTARATE; HYDROXY ACIDS; INTER-DOMAIN; L-SERINE; MOLECULAR MECHANISM; N-TERMINALS; PSEUDOMONAS AERUGINOSA; ROSSMANN FOLD; SITE DIRECTED MUTAGENESIS; STRUCTURAL STUDIES; SUBSTRATE SELECTIVITY; SUBSTRATE-BINDING SITES;

BACTERIA; BINDING SITES; CARBOXYLIC ACIDS; CATALYSIS; ENZYMES; METHANOL; SUBSTRATES;

AMINO ACIDS;

2 HYDROXYGLUTARIC ACID; 3 HYDROXY 2 METHYLPROPIONIC ACID; AMINO ACID; BACTERIAL PROTEIN; HYDROXYACID; NICOTINAMIDE ADENINE DINUCLEOTIDE; OXIDOREDUCTASE; PA0743 PROTEIN; SERINE; UBIQUITIN; UNCLASSIFIED DRUG;

AFFINITY CHROMATOGRAPHY; ALPHA HELIX; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CATABOLISM; CATALYSIS; CONTROLLED STUDY; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; MOLECULAR CLONING; MOLECULAR MECHANICS; MUTATIONAL ANALYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN PURIFICATION; PROTEIN STRUCTURE; PSEUDOMONAS AERUGINOSA; SITE DIRECTED MUTAGENESIS;

BACTERIAL PROTEINS; CATALYSIS; CRYSTALLOGRAPHY, X-RAY; MUTAGENESIS, SITE-DIRECTED; NAD; OXIDATION-REDUCTION; OXIDOREDUCTASES; PROTEIN STRUCTURE, TERTIARY; PSEUDOMONAS AERUGINOSA; SERINE; SUBSTRATE SPECIFICITY;

PSEUDOMONAS AERUGINOSA;

EID: 84863398742     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.294561     Document Type: Article

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