Crystal structure of novel NADP-dependent 3-hydroxyisobutyrate dehydrogenase from Thermus thermophilus HB8

Journal of Molecular Biology

Volumn 352, Issue 4, 2005, Pages 905-917

  Lokanath, Neratur K ^a   Ohshima, Noriyasu ^a   Takio, Koji ^a   Shiromizu, Ikuya ^a,b   Kuroishi, Chizu ^a   Okazaki, Nobuo ^a   Kuramitsu, Seiki ^a   Yokoyama, Shigeyuki ^a   Miyano, Masashi ^a   Kunishima, Naoki ^a  

^a RIKEN HARIMA INSTITUTE   (Japan)

^b MOCHIDA PHARMACEUTICAL CO   (Japan)

Author keywords

3 Hydroxyisobutyrate; 3 Hydroxyisobutyrate dehydrogenase; Crystal structure; Induced fit; Oligomerization

Indexed keywords

3 HYDROXYACID DEHYDROGENASE; 3 HYDROXYISOBUTYRATE DEHYDROGENASE; BACTERIAL ENZYME; ISOENZYME; LYSINE; NICOTINAMIDE; PHOSPHOGLUCONATE DEHYDROGENASE; SULFATE; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL STRAIN; CATALYSIS; CHIRALITY; COMPLEX FORMATION; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME BINDING; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SUBSTRATE; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN FOLDING; STRUCTURAL PROTEOMICS; THERMUS THERMOPHILUS;

BACTERIA (MICROORGANISMS); EUKARYOTA; THERMUS THERMOPHILUS;

EID: 24644525066     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2005.07.068     Document Type: Article

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