Crystal structures of homoserine dehydrogenase suggest a novel catalytic mechanism for oxidoreductases

Nature Structural Biology

Volumn 7, Issue 3, 2000, Pages 238-249

  DeLaBarre, Byron ^a   Thompson, Paul R ^a   Wright, Gerard D ^a   Berghuis, Albert M ^a  

^a MCMASTER UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

HOMOSERINE DEHYDROGENASE; OXIDOREDUCTASE;

ARTICLE; CATALYSIS; CRYSTAL STRUCTURE; DIMERIZATION; ENZYME ACTIVE SITE; ENZYME KINETICS; ENZYME MECHANISM; ENZYME STRUCTURE; PRIORITY JOURNAL; PROTEIN FOLDING; SACCHAROMYCES CEREVISIAE; SITE DIRECTED MUTAGENESIS; STRUCTURE ANALYSIS; X RAY DIFFRACTION;

APOENZYMES; BINDING SITES; CATALYSIS; CATALYTIC DOMAIN; CATIONS; CRYSTALLOGRAPHY, X-RAY; DIMERIZATION; HOLOENZYMES; HOMOSERINE; HOMOSERINE DEHYDROGENASE; HYDROGEN; METALS; MODELS, CHEMICAL; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; NAD; PROTEIN CONFORMATION; PROTEIN FOLDING; SACCHAROMYCES CEREVISIAE; STRUCTURE-ACTIVITY RELATIONSHIP;

SACCHAROMYCES CEREVISIAE;

EID: 0034006028     PISSN: 10728368     EISSN: None     Source Type: Journal    
DOI: 10.1038/73359     Document Type: Article

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