Fluorinated colloidal gold immunolabels for imaging select proteins in parallel with lipids using high-resolution secondary ion mass spectrometry

Bioconjugate Chemistry

Volumn 23, Issue 3, 2012, Pages 450-460

  Wilson, Robert L ^a   Frisz, Jessica F ^a   Hanafin, William P ^a   Carpenter, Kevin J ^b   Hutcheon, Ian D ^b   Weber, Peter K ^b   Kraft, Mary L ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b LAWRENCE LIVERMORE NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL MEMBRANES; COLLOIDS; CYTOLOGY; FIBER OPTIC SENSORS; GOLD NANOPARTICLES; ISOTOPES; METAL NANOPARTICLES; PROBES; PROTEINS; SECONDARY ION MASS SPECTROMETRY;

COLLOIDAL GOLD; COLLOIDAL GOLD NANOPARTICLES; FUNCTIONALIZED; HIGH RESOLUTION; LIPID SPECIES; MEMBRANE PROTEINS; NANOSIMS; PROTEIN ACTIVITY; PROTEIN SPECIES; SECONDARY ION-MASS SPECTROMETRY;

LIPIDS;

COLLOIDAL GOLD; FLUORINE; GOLD NANOPARTICLE; MEMBRANE LIPID; MEMBRANE PROTEIN;

ARTICLE; LIPID ANALYSIS; MASS SPECTROMETRY; MOLECULAR IMAGING; PROTEIN ANALYSIS;

EID: 84863393457     PISSN: 10431802     EISSN: 15204812     Source Type: Journal    
DOI: 10.1021/bc200482z     Document Type: Article

References (56)

1. Radhakrishnan, K., Halasz, A., Vlachos, D., and Edwards, J. S. (2010) Quantitative understanding of cell signaling: the importance of membrane organization Curr. Opin. Biotechnol. 21, 677-682
2. Metha, S. and Zhang, J. (2011) Reporting from the Field: Genetically Encoded Fluorescent Reporters Uncover Signaling Dynamics in Living Biological Systems Annu. Rev. Biochem. 80, 375-401
3. Shu, X., Lev-Ram, V., Deerinck, T. J., Qi, Y., Ramko, E. B., Davidson, M. W., Jin, Y., WEllisman, M. H., and Tsien, R. Y. (2011) A Genetically Encoded Tag for Correlated Light and Electron Microscopy of Intact Cells, Tissues, and Organisms PLoS Biol. 9, e1001041
4. Donaldson, J. G. (2002) Immunofluorescence Staining, in Current Protocols in Immunology pp 21.3.1-21.3.6, John Wiley & Sons, Inc.
5. Schwartzbach, S. D. D. and Osafune, T. (2010) in Methods in Molecular Biology (Walker, J. M., Ed.) Humana Press, New York.
6. Takeda, M., Leser, G. P., Russell, C. J., and Lamb, R. A. (2003) Influenza virus hemagglutinin concentrates in lipid raft microdomains for efficient viral fusion Proc. Natl. Acad. Sci. U.S.A. 100, 14610-14617 (Pubitemid 37521285)
7. Wilson, B. S., Steinberg, S. L., Liederman, K., Pfeiffer, J. R., Surviladze, Z., Zhang, J., Samelson, L. E., Yang, L., Kotula, P. G., and Oliver, J. M. (2004) Markers for detergent-resistant lipid rafts occupy distinct and dynamic domains in native membranes Mol. Biol. Cell 15, 2570-2592
8. Zheng, H., Chu, J., Qiu, Y., Loh, H. H., and Law, P. (2008) Agonist-selective signaling is determined by the receptor location within the domains Proc. Natl. Acad. Sci. U.S.A. 105, 9421-9426
9. Paila, Y. D., Ganguly, S., and Chattopadhyay, A. (2010) Metabolic Depletion of Sphingolipids Impairs Ligand Binding and Signaling of Human Serotonin1A Receptors Biochemistry 49, 2389-2397
10. 7(a) receptors in HeLa cells Acta Physiologica 190, 47-53 (Pubitemid 46570170)
11. Dowhan, W. and Bogdanov, M. (2011) Lipid-protein interactions as determinants of membrane protein structure and function Biochem. Soc. Trans. 39, 767-774
12. Zhao, J., Wu, J., Shao, H., Kong, F., Jain, N., Hunt, G., and Feigenson, G. W. (2007) Phase studies of model biomembranes: Macroscopic coexistence of Lα + Lβ with light-induced co-existence of Lα + Lo phases Biochim. Biophys. Acta 1768, 2777-2786 (Pubitemid 350060871)
13. Devaux, P. F., Fellmann, P., and Herve, P. (2002) Investigation on lipid asymmetry using lipid probes: Comparison between spin-labeled lipids and fluorescent lipids Chem. Phys. Lipids 116, 115-134 (Pubitemid 34686990)
14. Maier, O., Oberle, V., and Hoekstra, D. (2002) Fluorescent lipid probes: some properties and applications (a review) Chem. Phys. Lipids 116, 3-18 (Pubitemid 34686984)
15. Walker, A. V. (2008) Why is SIMS Underused in Chemical and Biological Analysis? Challenges and Opportunities Anal. Chem. 80, 8864-8870
16. Ostrowski, S. G., Van Bell, C. T., Winograd, N., and Ewing, A. G. (2004) Mass spectrometric imaging of highly curved membranes during tetrahymena mating Science 305, 71-73 (Pubitemid 38869371)
17. Piehowski, P. D., Davey, A. M., Kurczy, M. E., Sheets, E. D., Winograd, N., Ewing, A. G., and Heien, M. L. (2009) Time-of-Flight Secondary Ion Mass Spectrometry Imaging of Subcellular Lipid Heterogeneity: Poisson Counting and Spatial Resolution Anal. Chem. 81, 5593-5602
18. Kurczy, M. E., Piehowski, P. D., Van Bell, C. T., Heien, M. L., Winograd, N., and Ewing, A. G. (2010) Mass spectroscopy imaging of mating Tetrahymena show that changes in cell morphology relate to lipid domain formation Proc. Nat. Acad. Sci. U.S.A. 107, 2751-2756
19. Lockyer, N. P. and Vickerman, J. C. (2004) Progress in cellular analysis using ToF-SIMS Appl. Surface Sci. 212-232, 377-384
20. Guerquin-Kern, J.-L., Wu, T.-D., Quintana, C., and Croisy, A. (2005) Progress in analytical imaging of the cell by dynamic secondary ion mass spectrometry (SIMS microscopy) Biochim. Biophys. Acta 1724, 228-238 (Pubitemid 41080032)
21. Boxer, S. G., Kraft, M. L., and Weber, P. K. (2009) Advances in Imaging Secondary Ion Mass Spectrometry for Biological Samples Annu. Rev. Biophys. 38, 53-74
22. Anderton, C. R., Vaezian, B., Lou, K., Frisz, J. F., and Kraft, M. L. (2012) Identification of a Lipid-Related Peak Set to Enhance the Interpretation of TOF-SIMS Data from Model and Cellular Membranes Surf. Interface Anal. 44, 322-333
23. Anderton, C. R., Weber, P. K., Lou, K., Hutcheon, I. D., and Kraft, M. L. (2011) Correlated AFM and NanoSIMS imaging to probe cholesterol-induced changes in phase behavior and non-ideal mixing in ternary lipid membranes Biochim. Biophys. Acta 1808, 307-315
24. Vaezian, B., Anderton, C. R., and Kraft, M. L. (2010) Discriminating and Imaging Different Phosphatidylcholine Species within Phase-Separated Model Membranes by Principal Component Analysis of TOF-SIMS Images Anal. Chem. 82, 10006-10014
25. Sjovall, P., Lausmaa, J., and Johansson, B. (2004) Mass Spectrometric Imaging of Lipids in Brain Tissue Anal. Chem. 76, 4271-4278 (Pubitemid 39013993)
26. Malm, J., Giannaras, D., Riehle, M. O., Gadegaard, N., and Sjovall, P. (2009) Fixation and Drying Protocols for the Preparation of Cell Samples for Time-of-Flight Secondary Ion Mass Spectrometry Analysis Anal. Chem. 81, 7197-7205
27. Touboul, D., Halgand, F., Brunelle, A., Kersting, R., Tallarek, E., Hagenhoff, B., and Laprevote, O. (2004) Tissue Molecular Ion Imaging by Gold Cluster Ion Bombardment Anal. Chem. 76, 1550-1559 (Pubitemid 38338397)
28. Galli Marxer, C., Kraft, M. L., Weber, P. K., Hutcheon, I. D., and Boxer, S. G. (2005) Supported membrane composition analysis by secondary ion mass spectrometry with high lateral resolution Biophys. J. 88, 2965-2975 (Pubitemid 40983845)
29. Kraft, M. L., Weber, P. K., Longo, M. L., Hutcheon, I. D., and Boxer, S. G. (2006) Phase Separation of Lipid Membranes Analyzed with High-Resolution Secondary Ion Mass Spectrometry Science 313, 1948-1951 (Pubitemid 44497999)
30. Kraft, M. L., Fishel, S. F., Galli Marxer, C., Weber, P. K., Hutcheon, I. D., and Boxer, S. G. (2006) Quantitative analysis of supported membrane composition using the NanoSIMS Appl. Sur. Sci. 252, 6950-6956
31. Campbell, S., Gaus, K., Bittman, R., Jessup, W., Crowe, S., and Mak, J. (2004) The raft-promoting property of virion-associated cholesterol, but not the presence of virion-associated Brij 98 rafts, is a determinant of human immunodeficiency virus type 1 infectivity J. Virol. 78, 10556-10565 (Pubitemid 39258381)
32. Chigorno, V., Riva, C., Valsecchi, M., Nicolini, M., Brocca, P., and Sonnino, S. (1997) Metabolic processing of gangliosides by human fibroblasts in culture. Formation and recycling of separate pools of ganglioside Eur. J. Biochem. 250, 661-669 (Pubitemid 28022482)
33. Schwarzmann, G., Hoffmann-Bleihauer, P., Schubert, J., Sandhoff, K., and Marsh, D. (1983) Incorporation of ganglioside analogues into fibroblast cell membranes. A spin-label study Biochemistry 22, 5041-5048 (Pubitemid 14240699)
34. Wang, L. and Schultz, P. G. (2005) Expanding the Genetic Code Angew. Chem., Int. Ed. 44, 34-66 (Pubitemid 40069845)
35. Garg, P. K., Garg, S., and Zalutsky, M. R. (1991) Fluorine-18 labeling of monoclonal antibodies and fragments with preservation of immunoreactivity Bioconjugate Chem. 2, 44-49
36. Vaidyanathan, G. and Zalutsky, M. R. (1994) Improved synthesis of N-succinimidyl 4-[18F]fluorobenzoate and its application to the labeling of a monoclonal antibody fragment Bioconjugate Chem. 5, 352-356
37. Hess, S. T., Kumar, M., Verma, A., Farrington, J., Kenworthy, A., and Zimmerberg, J. (2005) Quantitative electron microscopy and fluorescence spectroscopy of the membrane distribution of influenza hemagglutinin J. Cell Bio. 169, 965-976 (Pubitemid 41002872)
38. Hess, S. T., Gould, T. J., Gudheti, M. V., Maas, S. A., Mills, K. D., and Zimmerberg, J. (2007) Dynamic clustered distribution of hemagglutinin resolved at 40 nm in living cell membranes discriminates between raft theories Proc. Natl. Acad. Sci. U.S.A. 104, 17370-17375 (Pubitemid 350219826)
39. Weisbecker, C. S., Merritt, M. V., and Whitesides, G. M. (1996) Molecular Self-Assembly of Aliphatic Thiols on Gold Colloids Langmuir 12, 3763-3772 (Pubitemid 126531338)
40. Kumar, S., Aaron, J., and Sokolov, K. (2008) Directional conjugation of antibodies to nanoparticles for synthesis of multiplexed optical contrast agents with both delivery and targeting moieties Nat. Protocols 3, 314-320 (Pubitemid 351266515)
41. Gosling, J. P. (2005) in A Practical Approach Series, Oxford University Press, Inc., New York.
42. Blight, E. G. and Dyer, W. J. (1959) A rapid method of total lipid extraction and purification Can. J. Biochem. Physiol. 37, 911-917
43. Ghosal, S., Fallon, S. J., Leighton, T. J., Wheeler, K. E., Kristo, M. J., Hutcheon, I. D., and Weber, P. K. (2008) Imaging and 3D Elemental Characterization of Intact Bacterial Spores by High-Resolution Secondary Ion Mass Spectrometry Anal. Chem. 80, 5986-5992
44. Lechene, C. P., Luyten, Y., McMahon, G., and Distel, D. L. (2007) Quantitative imaging of nitrogen fixation within animal cells Science 317, 1563-1566 (Pubitemid 47417438)
45. Johnson, S. R., Evans, S. D., and Brydson, R. (1998) Influence of a Terminal Functionality on the Physical Properties of Surfactant-Stabilized Gold Nanoparticles Langmuir 14, 6639-6647 (Pubitemid 128579138)
46. Selvakannan, P. R., Mandal, S., Phadtare, S., Pasricha, R., and Sastry, M. (2003) Capping of Gold Nanoparticles by the Amino Acid Lysine Renders Them Water-Dispersible Langmuir 19, 3545-3549
47. Templeton, A. C., Hostetler, M. J., Warmoth, E. K., Chen, S., Hartshorn, C. M., Krishnamurthy, V. M., Forbes, M. D. E., and Murray, R. W. (1998) Gateway Reactions to Diverse, Polyfunctional Monolayer-Protected Gold Clusters J. Am. Chem. Soc. 120, 4845-4849 (Pubitemid 28282738)
48. 2 Using Fluorinated Ligands J. Am. Chem. Soc. 122, 4245-4246 (Pubitemid 30304873)
49. Hiramatsu, H. and Osterloh, F. E. (2004) A Simple Large-Scale Synthesis of Nearly Monodisperse Gold and Silver Nanoparticles with Adjustable Sizes and with Exchangeable Surfactants Chem. Mater. 16, 2509-2511
50. Bergen en Henegouwen, P. M. P. and Leunissen, J. L. M. (1986) Controlled growth of colloidal gold particles and implications for labelling efficiency Histochem. Cell Biol. 85, 81-87
51. Kulp, K. S., Berman, E. S. F., Kinze, M. G., Shattuck, D. L., Nelson, E. J., Wu, L., Montgomery, J. L., Felton, J. S., and Wu, K. J. (2006) Chemical and biological differentiation of three human breast cancer cell types using time-of-flight secondary ion mass spectrometry Anal. Chem. 78, 3651-3658 (Pubitemid 43848958)
52. Oran, U., Unveren, E., Wirth, T., and Unger, W. E. S. (2004) Poly-dimethyl-siloxame (PDMS) contamination of polystyrene (PS) oligomers samples: a comparison of time-of-flight static secondary ion mass spectrometry (TOF-SSIMS) and X-ray photoelectron spectroscopy (XPS) results Appl. Surf. Sci. 227, 318-324
53. Jones, E. A., Lockyer, N. P., Kordys, J., and Vickerman, J. C. (2007) Suppression and Enhancement of Secondary Ion Formation Due to the Chemical Environment in Static-Secondary Ion Mass Spectrometry J. Am. Soc. Mass Spectrom. 18, 1559-1567 (Pubitemid 47096798)
54. Zhu, L., Johnson, C., and Bakovic, M. (2008) Stimulation of the human CTP: phosphatidylethanolamine cytidylyktransferase gene by early growth response protein 1 J. Lipid Res. 49, 2197-2211
55. Fujita, A., Cheng, J., and Fujimoto, T. (2009) Segregation of GM1 and GM3 clusters in the cell membrane depends on the intact actin cytoskeleton Biochim. Biophys. Acta 1791, 388-396
56. Brust, M., Walker, M., Bethell, D., Schiffrin, D. J., and Whyman, R. (1994) Synthesis of Thiol-derivatised Gold Nanoparticles in a Two-phase Liquid-Liquid System Chem. Commun. 7, 801-802