Decreased NKp46 and NKG2D and elevated PD-1 are associated with altered NK-cell function in pediatric transplant patients with PTLD

European Journal of Immunology

Volumn 42, Issue 2, 2012, Pages 541-550

  Wiesmayr, Silke ^a   Webber, Steven A ^a,b,c   Macedo, Camila ^a   Popescu, Iulia ^a   Smith, Louise ^b   Luce, Jane ^b   Metes, Diana ^a,c  

^a UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^b CHILDREN S HOSPITAL OF PITTSBURGH   (United States)

^c UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

EBV; NK cells; Pediatric; PTLD; Thoracic organ transplantation

Indexed keywords

CD16 ANTIGEN; CD56 ANTIGEN; GAMMA INTERFERON; NATURAL CYTOTOXICITY TRIGGERING RECEPTOR 1; NATURAL KILLER CELL RECEPTOR NKG2D; PROGRAMMED DEATH 1 RECEPTOR;

ADOLESCENT; ADULT; ARTICLE; CELL FUNCTION; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; CYTOKINE RELEASE; CYTOTOXICITY; DOWN REGULATION; EPSTEIN BARR VIRUS INFECTION; FEMALE; GRAFT RECIPIENT; HUMAN; HUMAN CELL; IMMUNOPATHOGENESIS; LYMPHOPROLIFERATIVE DISEASE; MALE; NATURAL KILLER CELL; PHENOTYPE; POSTTRANSPLANTATION LYMPHOPROLIFERATIVE DISORDER; PRESCHOOL CHILD; PRIORITY JOURNAL; SCHOOL CHILD; SIGNAL TRANSDUCTION; UPREGULATION;

ADOLESCENT; ANTIGENS, CD56; CELL GROWTH PROCESSES; CELLS, CULTURED; CHILD; CHILD, PRESCHOOL; CYTOTOXICITY, IMMUNOLOGIC; EPSTEIN-BARR VIRUS INFECTIONS; FEMALE; GENE EXPRESSION REGULATION; HEART TRANSPLANTATION; HERPESVIRUS 4, HUMAN; HUMANS; IMMUNOSUPPRESSION; INFANT; KILLER CELLS, NATURAL; LUNG TRANSPLANTATION; LYMPHOPROLIFERATIVE DISORDERS; MALE; NATURAL CYTOTOXICITY TRIGGERING RECEPTOR 1; NK CELL LECTIN-LIKE RECEPTOR SUBFAMILY K; POSTOPERATIVE COMPLICATIONS; PROGRAMMED CELL DEATH 1 RECEPTOR;

EID: 84863393455     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201141832     Document Type: Article

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