메뉴 건너뛰기




Volumn 179, Issue 5, 2007, Pages 3362-3370

Natural killer cells in perinatally HIV-1-infected children exhibit less degranulation compared to HIV-1-exposed uninfected children and their expression of KIR2DL3, NKG2C, and NKp46 correlates with disease severity

Author keywords

[No Author keywords available]

Indexed keywords

CD16 ANTIGEN; CD56 ANTIGEN; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR 2DL3; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; NATURAL KILLER CELL RECEPTOR; NATURAL KILLER CELL RECEPTOR 46; NATURAL KILLER CELL RECEPTOR NKG2C; PROTEIN P46; UNCLASSIFIED DRUG; IMMUNOGLOBULIN RECEPTOR; KIR2DL3 PROTEIN, HUMAN; NATURAL KILLER CELL ACTIVATING RECEPTORS; NCR1 PROTEIN, HUMAN;

EID: 38449121925     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.179.5.3362     Document Type: Article
Times cited : (60)

References (73)
  • 1
    • 0024792513 scopus 로고
    • Biology of natural killer cells
    • Trinchieri, G. 1989. Biology of natural killer cells. Adv. Immunol. 47: 187-376.
    • (1989) Adv. Immunol , vol.47 , pp. 187-376
    • Trinchieri, G.1
  • 5
    • 0022616253 scopus 로고
    • Selective rejection of H-2-deficient lymphoma variants suggests alternative immune defence strategy
    • Karre, K., H. G. Ljunggren, G. Piontek, and R. Kiessling. 1986. Selective rejection of H-2-deficient lymphoma variants suggests alternative immune defence strategy. Nature 319: 675-678.
    • (1986) Nature , vol.319 , pp. 675-678
    • Karre, K.1    Ljunggren, H.G.2    Piontek, G.3    Kiessling, R.4
  • 6
    • 0036215134 scopus 로고    scopus 로고
    • KIR: Diverse, rapidly evolving receptors of innate and adaptive immunity
    • Vilches, C., and P. Parham. 2002. KIR: diverse, rapidly evolving receptors of innate and adaptive immunity. Annu. Rev. Immunol. 20: 217-251.
    • (2002) Annu. Rev. Immunol , vol.20 , pp. 217-251
    • Vilches, C.1    Parham, P.2
  • 7
    • 1642473189 scopus 로고    scopus 로고
    • The inhibitory NK cell receptor CD94/NKG2A and the activating receptor CD94/ NKG2C bind the top of HLA-E through mostly shared but partly distinct sets of HLA-E residues
    • Wada, H., N. Matsumoto, K. Maenaka, K. Suzuki, and K. Yamamoto. 2004. The inhibitory NK cell receptor CD94/NKG2A and the activating receptor CD94/ NKG2C bind the top of HLA-E through mostly shared but partly distinct sets of HLA-E residues. Eur. J. Immunol. 34: 81-90.
    • (2004) Eur. J. Immunol , vol.34 , pp. 81-90
    • Wada, H.1    Matsumoto, N.2    Maenaka, K.3    Suzuki, K.4    Yamamoto, K.5
  • 8
    • 0033618504 scopus 로고    scopus 로고
    • Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA
    • Bauer, S., V. Groh, J. Wu, A. Steinle, J. H. Phillips, L. L. Lanier, and T. Spies. 1999. Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA. Science 285: 727-729.
    • (1999) Science , vol.285 , pp. 727-729
    • Bauer, S.1    Groh, V.2    Wu, J.3    Steinle, A.4    Phillips, J.H.5    Lanier, L.L.6    Spies, T.7
  • 10
    • 0035099068 scopus 로고    scopus 로고
    • ULBPs, novel MHC class I-related molecules, bind to CMV glycoprotein UL16 and stimulate NK cytotoxicity through the NKG2D receptor
    • Cosman, D., J. Mullberg, C. L. Sutherland, W. Chin, R. Armitage, W. Fanslow, M. Kubin, and N. J. Chalupny. 2001. ULBPs, novel MHC class I-related molecules, bind to CMV glycoprotein UL16 and stimulate NK cytotoxicity through the NKG2D receptor. Immunity 14: 123-133.
    • (2001) Immunity , vol.14 , pp. 123-133
    • Cosman, D.1    Mullberg, J.2    Sutherland, C.L.3    Chin, W.4    Armitage, R.5    Fanslow, W.6    Kubin, M.7    Chalupny, N.J.8
  • 12
    • 29144444611 scopus 로고    scopus 로고
    • Cutting edge: Lectin-like transcript-1 is a ligand for the inhibitory human NKR-P1A receptor
    • Rosen, D. B., J. Bettadapura, M. Alsharifi, P. A. Mathew, H. S. Warren, and L. L. Lanier. 2005. Cutting edge: lectin-like transcript-1 is a ligand for the inhibitory human NKR-P1A receptor. J. Immunol. 175: 7796-7799.
    • (2005) J. Immunol , vol.175 , pp. 7796-7799
    • Rosen, D.B.1    Bettadapura, J.2    Alsharifi, M.3    Mathew, P.A.4    Warren, H.S.5    Lanier, L.L.6
  • 13
    • 0032945045 scopus 로고    scopus 로고
    • NKp46 is the major triggering receptor involved in the natural cytotoxicity of fresh or cultured human NK cells: Correlation between surface density of NKp46 and natural cytotoxicity against autologous, allogeneic or xenogeneic target cells
    • Sivori, S., D. Pende, C. Bottino, E. Marcenaro, A. Pessino, R. Biassoni, L. Moretta, and A. Moretta. 1999. NKp46 is the major triggering receptor involved in the natural cytotoxicity of fresh or cultured human NK cells: correlation between surface density of NKp46 and natural cytotoxicity against autologous, allogeneic or xenogeneic target cells. Eur. J. Immunol. 29: 1656-1666.
    • (1999) Eur. J. Immunol , vol.29 , pp. 1656-1666
    • Sivori, S.1    Pende, D.2    Bottino, C.3    Marcenaro, E.4    Pessino, A.5    Biassoni, R.6    Moretta, L.7    Moretta, A.8
  • 16
    • 23344448979 scopus 로고    scopus 로고
    • + T cells during HIV-1 infection: A gp41 peptide induces the expression of an NKp44 ligand
    • + T cells during HIV-1 infection: a gp41 peptide induces the expression of an NKp44 ligand. Proc. Natl. Acad. Sci. USA 102: 10981-10986.
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 10981-10986
    • Vieillard, V.1    Strominger, J.L.2    Debre, P.3
  • 20
    • 0025108226 scopus 로고
    • Development of natural killer cytotoxicity during childhood: Marked increases in number of natural killer cells with adequate cytotoxic abilities during infancy to early childhood
    • Yabuhara, A., H. Kawai, and A. Komiyama. 1990. Development of natural killer cytotoxicity during childhood: marked increases in number of natural killer cells with adequate cytotoxic abilities during infancy to early childhood. Pediatr. Res. 28: 316-322.
    • (1990) Pediatr. Res , vol.28 , pp. 316-322
    • Yabuhara, A.1    Kawai, H.2    Komiyama, A.3
  • 21
    • 0242353358 scopus 로고    scopus 로고
    • Age-related changes in intracellular TH1/TH2 cytokine production, immunoproliferative T lymphocyte response and natural killer cell activity in newborns, children and adults
    • Gasparoni, A., L. Ciardelli, A. Avanzini, A. M. Castellazzi, R. Carini, G. Rondini, and G. Chirico. 2003. Age-related changes in intracellular TH1/TH2 cytokine production, immunoproliferative T lymphocyte response and natural killer cell activity in newborns, children and adults. Biol. Neonate 84: 297-303.
    • (2003) Biol. Neonate , vol.84 , pp. 297-303
    • Gasparoni, A.1    Ciardelli, L.2    Avanzini, A.3    Castellazzi, A.M.4    Carini, R.5    Rondini, G.6    Chirico, G.7
  • 23
    • 0019464224 scopus 로고
    • Interferon induction of natural killer cytotoxicity in human neonates
    • Kohl, S., J. J. Frazier, S. B. Greenberg, L. K. Pickering, and L. S. Loo. 1981. Interferon induction of natural killer cytotoxicity in human neonates. J. Pediatr. 98: 379-384.
    • (1981) J. Pediatr , vol.98 , pp. 379-384
    • Kohl, S.1    Frazier, J.J.2    Greenberg, S.B.3    Pickering, L.K.4    Loo, L.S.5
  • 24
    • 0023933434 scopus 로고
    • Defects in interleukin-2 stimulation of neonatal natural killer cytotoxicity to herpes simplex virus-infected cells
    • Kohl, S., M. S. West, and L. S. Loo. 1988. Defects in interleukin-2 stimulation of neonatal natural killer cytotoxicity to herpes simplex virus-infected cells. J. Pediatr. 112: 976-981.
    • (1988) J. Pediatr , vol.112 , pp. 976-981
    • Kohl, S.1    West, M.S.2    Loo, L.S.3
  • 25
    • 0022649701 scopus 로고
    • Immunologic basis for increased susceptibility of the neonate to infection
    • Wilson, C. B. 1986. Immunologic basis for increased susceptibility of the neonate to infection. J. Pediatr. 108: 1-12.
    • (1986) J. Pediatr , vol.108 , pp. 1-12
    • Wilson, C.B.1
  • 27
    • 0027133666 scopus 로고
    • Functional and phenotypic assessment of neonatal human leucocytes expressing natural killer cell-associated antigens
    • Bradstock, K. F., C. Luxford, and P. G. Grimsley. 1993. Functional and phenotypic assessment of neonatal human leucocytes expressing natural killer cell-associated antigens. Immunol. Cell. Biol. 71: 535-542.
    • (1993) Immunol. Cell. Biol , vol.71 , pp. 535-542
    • Bradstock, K.F.1    Luxford, C.2    Grimsley, P.G.3
  • 28
    • 0026703569 scopus 로고
    • Characterization of lymphocyte subpopulations in cord blood
    • Rabian-Herzog, C., S. Lesage, and E. Gluckman. 1992. Characterization of lymphocyte subpopulations in cord blood. Bone Marrow Transplant. 9(Suppl. 1): 64-67.
    • (1992) Bone Marrow Transplant , vol.9 , Issue.SUPPL. 1 , pp. 64-67
    • Rabian-Herzog, C.1    Lesage, S.2    Gluckman, E.3
  • 30
    • 0021815642 scopus 로고
    • + granular lymphocytes with a natural killer-sensitive tumor cell, K562
    • + granular lymphocytes with a natural killer-sensitive tumor cell, K562. J. Exp. Med. 161: 1464-1482.
    • (1985) J. Exp. Med , vol.161 , pp. 1464-1482
    • Phillips, J.H.1    Lanier, L.L.2
  • 32
    • 0141650530 scopus 로고    scopus 로고
    • The impaired NK cell cytolytic function in viremic HIV-1 infection is associated with a reduced surface expression of natural cytotoxicity receptors (NKp46, NKp30 and NKp44)
    • De Maria, A., M. Fogli, P. Costa, G. Murdaca, F. Puppo, D. Mavilio, A. Moretta, and L. Moretta. 2003. The impaired NK cell cytolytic function in viremic HIV-1 infection is associated with a reduced surface expression of natural cytotoxicity receptors (NKp46, NKp30 and NKp44). Eur. J. Immunol. 33: 2410-2418.
    • (2003) Eur. J. Immunol , vol.33 , pp. 2410-2418
    • De Maria, A.1    Fogli, M.2    Costa, P.3    Murdaca, G.4    Puppo, F.5    Mavilio, D.6    Moretta, A.7    Moretta, L.8
  • 34
    • 34247612099 scopus 로고    scopus 로고
    • Synergy or independence? Deciphering the interaction of HLA class I and NK cell KIR alleles in early HIV-1 disease progression
    • Barbour, J. D., U. Sriram, S. J. Caillier, J. A. Levy, F. M. Hecht, and J. R. Oksenberg. 2007. Synergy or independence? Deciphering the interaction of HLA class I and NK cell KIR alleles in early HIV-1 disease progression. PLoS Pathog. 3: E43.
    • (2007) PLoS Pathog , vol.3
    • Barbour, J.D.1    Sriram, U.2    Caillier, S.J.3    Levy, J.A.4    Hecht, F.M.5    Oksenberg, J.R.6
  • 35
    • 28544441628 scopus 로고    scopus 로고
    • Killer immunoglobulin-like receptors and HLA act both independently and synergistically to modify HIV disease progression
    • Gaudieri, S., D. DeSantis, E. McKinnon, C. Moore, D. Nolan, C. S. Witt, S. A. Mallal, and F. T. Christiansen. 2005. Killer immunoglobulin-like receptors and HLA act both independently and synergistically to modify HIV disease progression. Genes Immun. 6: 683-690.
    • (2005) Genes Immun , vol.6 , pp. 683-690
    • Gaudieri, S.1    DeSantis, D.2    McKinnon, E.3    Moore, C.4    Nolan, D.5    Witt, C.S.6    Mallal, S.A.7    Christiansen, F.T.8
  • 36
    • 33846200446 scopus 로고    scopus 로고
    • Cutting edge: KIR3DS1, a gene implicated in resistance to progression to AIDS, encodes a DAP12-associated receptor expressed on NK cells that triggers NK cell activation
    • Carr, W. H., D. B. Rosen, H. Arase, D. F. Nixon, J. Michaelsson, and L. L. Lanier. 2007. Cutting edge: KIR3DS1, a gene implicated in resistance to progression to AIDS, encodes a DAP12-associated receptor expressed on NK cells that triggers NK cell activation. J. Immunol. 178: 647-651.
    • (2007) J. Immunol , vol.178 , pp. 647-651
    • Carr, W.H.1    Rosen, D.B.2    Arase, H.3    Nixon, D.F.4    Michaelsson, J.5    Lanier, L.L.6
  • 37
    • 33750802673 scopus 로고    scopus 로고
    • Cutting edge: Resistance to HIV-1 infection among African female sex workers is associated with inhibitory KIR in the absence of their HLA ligands
    • Jennes, W., S. Verheyden, C. Demanet, C. A. Adje-Toure, B. Vuylsteke, J. N. Nkengasong, and L. Kestens. 2006. Cutting edge: resistance to HIV-1 infection among African female sex workers is associated with inhibitory KIR in the absence of their HLA ligands. J. Immunol. 177: 6588-6592.
    • (2006) J. Immunol , vol.177 , pp. 6588-6592
    • Jennes, W.1    Verheyden, S.2    Demanet, C.3    Adje-Toure, C.A.4    Vuylsteke, B.5    Nkengasong, J.N.6    Kestens, L.7
  • 38
    • 0036604132 scopus 로고    scopus 로고
    • Sustained impairment of IFN-γ secretion in suppressed HIV-infected patients despite mature NK cell recovery: Evidence for a defective reconstitution of innate immunity
    • Azzoni, L., E. Papasavvas, J. Chehimi, J. R. Kostman, K. Mounzer, J. Ondercin, B. Perussia, and L. J. Montaner. 2002. Sustained impairment of IFN-γ secretion in suppressed HIV-infected patients despite mature NK cell recovery: evidence for a defective reconstitution of innate immunity. J. Immunol. 168: 5764-5770.
    • (2002) J. Immunol , vol.168 , pp. 5764-5770
    • Azzoni, L.1    Papasavvas, E.2    Chehimi, J.3    Kostman, J.R.4    Mounzer, K.5    Ondercin, J.6    Perussia, B.7    Montaner, L.J.8
  • 39
  • 42
    • 0029084614 scopus 로고
    • Defective natural immunity: An early manifestation of human immunodeficiency virus infection
    • Ullum, H., P. C. Gotzsche, J. Victor, E. Dickmeiss, P. Skinhoj, and B. K. Pedersen. 1995. Defective natural immunity: an early manifestation of human immunodeficiency virus infection. J. Exp. Med. 182: 789-799.
    • (1995) J. Exp. Med , vol.182 , pp. 789-799
    • Ullum, H.1    Gotzsche, P.C.2    Victor, J.3    Dickmeiss, E.4    Skinhoj, P.5    Pedersen, B.K.6
  • 43
    • 0029987168 scopus 로고    scopus 로고
    • Antibody-dependent cellular cytotoxicity in HIV infections
    • Ahmad, A., and J. Menezes. 1996. Antibody-dependent cellular cytotoxicity in HIV infections. FASEB J. 10: 258-266.
    • (1996) FASEB J , vol.10 , pp. 258-266
    • Ahmad, A.1    Menezes, J.2
  • 45
    • 0024542789 scopus 로고
    • Natural and antibody-dependent cytotoxicity in different clinical stages of human immunodeficiency virus type 1 infection
    • Ljunggren, K., A. Karlson, E. M. Fenyo, and M. Jondal. 1989. Natural and antibody-dependent cytotoxicity in different clinical stages of human immunodeficiency virus type 1 infection. Clin. Exp. Immunol. 75: 184-189.
    • (1989) Clin. Exp. Immunol , vol.75 , pp. 184-189
    • Ljunggren, K.1    Karlson, A.2    Fenyo, E.M.3    Jondal, M.4
  • 48
    • 0027222946 scopus 로고
    • Natural killer cytotoxicity and antibody-dependent cellular cytotoxicity of human immunodeficiency virus-infected cells by leukocytes from human neonates and adults
    • Jenkins, M., J. Mills, and S. Kohl. 1993. Natural killer cytotoxicity and antibody-dependent cellular cytotoxicity of human immunodeficiency virus-infected cells by leukocytes from human neonates and adults. Pediatr. Res. 33: 469-474.
    • (1993) Pediatr. Res , vol.33 , pp. 469-474
    • Jenkins, M.1    Mills, J.2    Kohl, S.3
  • 50
    • 9344222211 scopus 로고    scopus 로고
    • Neonatal natural killer cells produce chemokines and suppress HIV replication in vitro
    • Bernstein, H. B., A. L. Kinter, R. Jackson, and A. S. Fauci. 2004. Neonatal natural killer cells produce chemokines and suppress HIV replication in vitro. AIDS Res. Hum. Retroviruses 20: 1189-1195.
    • (2004) AIDS Res. Hum. Retroviruses , vol.20 , pp. 1189-1195
    • Bernstein, H.B.1    Kinter, A.L.2    Jackson, R.3    Fauci, A.S.4
  • 52
    • 10344255635 scopus 로고    scopus 로고
    • CD107a as a functional marker for the identification of natural killer cell activity
    • Alter, G., J. M. Malenfant, and M. Altfeld. 2004. CD107a as a functional marker for the identification of natural killer cell activity. J. Immunol. Methods 294: 15-22.
    • (2004) J. Immunol. Methods , vol.294 , pp. 15-22
    • Alter, G.1    Malenfant, J.M.2    Altfeld, M.3
  • 53
    • 16644378159 scopus 로고    scopus 로고
    • Detection of T-cell degranulation: CD107a and b
    • Betts, M. R., and R. A. Koup. 2004. Detection of T-cell degranulation: CD107a and b. Methods Cell. Biol. 75: 497-512.
    • (2004) Methods Cell. Biol , vol.75 , pp. 497-512
    • Betts, M.R.1    Koup, R.A.2
  • 54
    • 0034699507 scopus 로고    scopus 로고
    • A practical approach to multicolor flow cytometry for immunophenotyping
    • Baumgarth, N., and M. Roederer. 2000. A practical approach to multicolor flow cytometry for immunophenotyping. J. Immunol. Methods 243: 77-97.
    • (2000) J. Immunol. Methods , vol.243 , pp. 77-97
    • Baumgarth, N.1    Roederer, M.2
  • 55
    • 3543069879 scopus 로고    scopus 로고
    • Seventeen-colour flow cytometry: Unravelling the immune system
    • Perfetto, S. P., P. K. Chattopadhyay, and M. Roederer. 2004. Seventeen-colour flow cytometry: unravelling the immune system. Nat. Rev. Immunol. 4: 648-655.
    • (2004) Nat. Rev. Immunol , vol.4 , pp. 648-655
    • Perfetto, S.P.1    Chattopadhyay, P.K.2    Roederer, M.3
  • 56
    • 0035503984 scopus 로고    scopus 로고
    • Spectral compensation for flow cytometry: Visualization artifacts, limitations, and caveats
    • Roederer, M. 2001. Spectral compensation for flow cytometry: visualization artifacts, limitations, and caveats. Cytometry 45: 194-205.
    • (2001) Cytometry , vol.45 , pp. 194-205
    • Roederer, M.1
  • 57
    • 0027184018 scopus 로고
    • The role of natural killer cells in innate resistance to infection
    • Bancroft, G. J. 1993. The role of natural killer cells in innate resistance to infection. Curr. Opin. Immunol. 5: 503-510.
    • (1993) Curr. Opin. Immunol , vol.5 , pp. 503-510
    • Bancroft, G.J.1
  • 58
    • 0035496603 scopus 로고    scopus 로고
    • Natural killer cells, viruses and cancer
    • Cerwenka, A., and L. L. Lanier. 2001. Natural killer cells, viruses and cancer. Nat. Rev. Immunol. 1: 41-49.
    • (2001) Nat. Rev. Immunol , vol.1 , pp. 41-49
    • Cerwenka, A.1    Lanier, L.L.2
  • 59
    • 0037290831 scopus 로고    scopus 로고
    • Natural killer cells and viral infections
    • French, A. R., and W. M. Yokoyama. 2003. Natural killer cells and viral infections. Curr. Opin. Immunol. 15: 45-51.
    • (2003) Curr. Opin. Immunol , vol.15 , pp. 45-51
    • French, A.R.1    Yokoyama, W.M.2
  • 60
    • 0022525467 scopus 로고
    • Deficiency of natural killer activity, but not of natural killer binding, in patients with lymphoadenopathy syndrome positive for antibodies to HTLV-III
    • Fontana, L., M. C. Sirianni, G. de Sanctis, M. Carbonari, B. Ensoli, and F. Aiuti. 1986. Deficiency of natural killer activity, but not of natural killer binding, in patients with lymphoadenopathy syndrome positive for antibodies to HTLV-III. Immunobiology 171: 425-435.
    • (1986) Immunobiology , vol.171 , pp. 425-435
    • Fontana, L.1    Sirianni, M.C.2    de Sanctis, G.3    Carbonari, M.4    Ensoli, B.5    Aiuti, F.6
  • 61
    • 0347382282 scopus 로고    scopus 로고
    • Loss of the CD56hiCD16- NK cell subset and NK cell interferon-γ production during antiretroviral therapy for HIV-1: Partial recovery by human growth hormone
    • Goodier, M. R., N. Imami, G. Moyle, B. Gazzard, and F. Gotch. 2003. Loss of the CD56hiCD16- NK cell subset and NK cell interferon-γ production during antiretroviral therapy for HIV-1: partial recovery by human growth hormone. Clin. Exp. Immunol. 134: 470-476.
    • (2003) Clin. Exp. Immunol , vol.134 , pp. 470-476
    • Goodier, M.R.1    Imami, N.2    Moyle, G.3    Gazzard, B.4    Gotch, F.5
  • 64
    • 0345714615 scopus 로고    scopus 로고
    • Short-term risk of disease progression in HIV-1-infected children receiving no antiretroviral therapy or zidovudine monotherapy: A meta-analysis
    • Dunn, D. 2003. Short-term risk of disease progression in HIV-1-infected children receiving no antiretroviral therapy or zidovudine monotherapy: a meta-analysis. Lancet 362: 1605-1611.
    • (2003) Lancet , vol.362 , pp. 1605-1611
    • Dunn, D.1
  • 65
    • 27544500878 scopus 로고    scopus 로고
    • Switch from inhibitory to activating NKG2 receptor expression in HIV-1 infection: Lack of reversion with highly active antiretroviral therapy
    • Mela, C. M., C. T. Burton, N. Imami, M. Nelson, A. Steel, B. G. Gazzard, F. M. Gotch, and M. R. Goodier. 2005. Switch from inhibitory to activating NKG2 receptor expression in HIV-1 infection: lack of reversion with highly active antiretroviral therapy. AIDS 19: 1761-1769.
    • (2005) AIDS , vol.19 , pp. 1761-1769
    • Mela, C.M.1    Burton, C.T.2    Imami, N.3    Nelson, M.4    Steel, A.5    Gazzard, B.G.6    Gotch, F.M.7    Goodier, M.R.8
  • 66
    • 33745211470 scopus 로고    scopus 로고
    • Human cytomegalovirus infection is associated with increased proportions of NK cells that express the CD94/NKG2C receptor in aviremic HIV-1-positive patients
    • Guma, M., C. Cabrera, I. Erkizia, M. Bofill, B. Clotet, L. Ruiz, and M. Lopez-Botet. 2006. Human cytomegalovirus infection is associated with increased proportions of NK cells that express the CD94/NKG2C receptor in aviremic HIV-1-positive patients. J. Infect. Dis. 194: 38-41.
    • (2006) J. Infect. Dis , vol.194 , pp. 38-41
    • Guma, M.1    Cabrera, C.2    Erkizia, I.3    Bofill, M.4    Clotet, B.5    Ruiz, L.6    Lopez-Botet, M.7
  • 67
    • 4644279778 scopus 로고    scopus 로고
    • Killing of human immunodeficiency virus-infected primary T-cell blasts by autologous natural killer cells is dependent on the ability of the virus to alter the expression of major histocompatibility complex class I molecules
    • Bonaparte, M. I., and E. Barker. 2004. Killing of human immunodeficiency virus-infected primary T-cell blasts by autologous natural killer cells is dependent on the ability of the virus to alter the expression of major histocompatibility complex class I molecules. Blood 104: 2087-2094.
    • (2004) Blood , vol.104 , pp. 2087-2094
    • Bonaparte, M.I.1    Barker, E.2
  • 68
    • 0037423824 scopus 로고    scopus 로고
    • Inability of natural killer cells to destroy autologous HIV-infected T lymphocytes
    • Bonaparte, M. I., and E. Barker. 2003. Inability of natural killer cells to destroy autologous HIV-infected T lymphocytes. AIDS 17: 487-494.
    • (2003) AIDS , vol.17 , pp. 487-494
    • Bonaparte, M.I.1    Barker, E.2
  • 69
    • 33746255665 scopus 로고    scopus 로고
    • Low perforin and elevated SHIP-1 expression is associated with functional anergy of natural killer cells in chronic HIV-1 infection
    • Alter, G., T. J. Suscovich, M. Kleyman, N. Teigen, H. Streeck, M. T. Zaman, A. Meier, and M. Altfeld. 2006. Low perforin and elevated SHIP-1 expression is associated with functional anergy of natural killer cells in chronic HIV-1 infection. AIDS 20: 1549-1551.
    • (2006) AIDS , vol.20 , pp. 1549-1551
    • Alter, G.1    Suscovich, T.J.2    Kleyman, M.3    Teigen, N.4    Streeck, H.5    Zaman, M.T.6    Meier, A.7    Altfeld, M.8
  • 70
    • 33745924387 scopus 로고    scopus 로고
    • Differential expression of perforin in cytotoxic lymphocyte in HIV/AIDS patients of China
    • Qi, W., J. Yongjun, W. Yanan, Z. Zining, H. Xiaoxu, L. Jing, and S. Hong. 2006. Differential expression of perforin in cytotoxic lymphocyte in HIV/AIDS patients of China. J. Clin. Immunol. 26: 339-346.
    • (2006) J. Clin. Immunol , vol.26 , pp. 339-346
    • Qi, W.1    Yongjun, J.2    Yanan, W.3    Zining, Z.4    Xiaoxu, H.5    Jing, L.6    Hong, S.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.