Dehydrodiconiferyl alcohol isolated from Cucurbita moschata shows anti-adipogenic and anti-lipogenic effects in 3T3-L1 cells and primary mouse embryonic fibroblasts

Journal of Biological Chemistry

Volumn 287, Issue 12, 2012, Pages 8839-8851

  Lee, Junghun ^a   Kim, Donghyun ^a,e   Choi, Jonghyun ^a   Choi, Hyounjeong ^a   Ryu, Jae Ha ^b   Jeong, Jinhyun ^c   Park, Eun Jin ^d   Kim, Seon Hee ^d   Kim, Sunyoung ^a  

^a Seoul National University   (South Korea)

^b Sookmyung Women's University   (South Korea)

^c Yonsei University   (South Korea)

^d Viromed Co Ltd   (South Korea)

^e UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPOCYTE DIFFERENTIATION; ADIPOCYTES; ADIPOGENESIS; BIOLOGICAL CHARACTERISTIC; BIOLOGICALLY ACTIVE COMPOUNDS; CCAAT/ENHANCER-BINDING PROTEINS; CELL DIVISIONS; CELL VIABILITY; CLONAL EXPANSION; CUCURBITA MOSCHATA; CYCLIN-DEPENDENT KINASE; DIET-INDUCED OBESITY; DNA BINDING ACTIVITY; DNA SYNTHESISS; FATTY ACID-BINDING PROTEINS; LIPID ACCUMULATIONS; LIPOGENESIS; MARKER GENES; MASS SPECTROMETRY ANALYSIS; MOUSE EMBRYONIC FIBROBLASTS; MOUSE MODELS; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR; PREADIPOCYTES; PRODUCTION LEVEL; SOLVENT FRACTIONATION; STAINING METHOD;

BIOACTIVITY; CELL CULTURE; CELL PROLIFERATION; FIBROBLASTS; GENE EXPRESSION; MAMMALS; MASS SPECTROMETRY; MOLECULAR WEIGHT; NUTRITION; PROTEINS; SOLVENT EXTRACTION; THIN LAYER CHROMATOGRAPHY;

BIOSYNTHESIS;

ACYL COENZYME A DESATURASE; ANTIOBESITY AGENT; CCAAT ENHANCER BINDING PROTEIN BETA; CUCURBITA MOSCHATA EXTRACT; CYCLIN A; CYCLIN DEPENDENT KINASE 2; DEHYDRODICONIFERYL ALCOHOL; PLANT EXTRACT; STEAROYL COENZYME A DESATURASE 1; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; UNCLASSIFIED DRUG;

ADIPOCYTE; ADIPOGENESIS; ANIMAL CELL; ANTIADIPOGENIC ACTIVITY; ANTILIPOGENIC ACTIVITY; ARTICLE; CEBPA GENE; CELL DIVISION; CELL STRAIN 3T3; CELL VIABILITY; CONTROLLED STUDY; CUCURBITA MOSCHATA; DNA BINDING; DNA SYNTHESIS; DRUG ACTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; EMBRYO; FABP4 GENE; FIBROBLAST; GENE EXPRESSION; LIPID STORAGE; LIPOGENESIS; MARKER GENE; MASS SPECTROMETRY; MITOSIS; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PPARG GENE; PRIORITY JOURNAL; PROADIPOCYTE; PROTEIN EXPRESSION; PROTEIN FUNCTION; SCD GENE; SREBP1C GENE;

3T3-L1 CELLS; ADIPOCYTES; ADIPOGENESIS; ANIMALS; CCAAT-ENHANCER-BINDING PROTEIN-ALPHA; CELL DIFFERENTIATION; CELLS, CULTURED; CUCURBITA; FIBROBLASTS; GENE EXPRESSION; HUMANS; LIPOGENESIS; MICE; OBESITY; PHENOLS; PLANT EXTRACTS; PPAR GAMMA;

CUCURBITA MOSCHATA; CYCLINA;

EID: 84863373195     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.263434     Document Type: Article

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