Structure-function studies of a plant tyrosyl-DNA phosphodiesterase provide novel insights into DNA repair mechanisms of Arabidopsis thaliana

Biochemical Journal

Volumn 443, Issue 1, 2012, Pages 49-56

  Kim, Hoyeun ^a   Na, Sang Hyeon ^a   Lee, So Young ^a   Jeong, Young Min ^a   Hwang, Hyun Ju ^a   Hur, Jae Young ^a   Park, Sang Hyun ^a   Woo, Je Chang ^b   Kim, Sang Gu ^a  

^a Seoul National University   (South Korea)

^b Mokpo National University   (South Korea)

Author keywords

Arabidopsis; Enzyme kinetics; SMAD forkheadassociated domain; Tyrosyl DNA phosphodiesterase (TDP) domain; Tyrosyl DNA phosphodiesterase 1 (TDP1); Vanadate analogue

Indexed keywords

CAMPTOTHECIN; HISTIDINE; LYSINE; PHOSPHOLIPASE D; SINGLE STRANDED DNA; TYROSYL DNA PHOSPHODIESTERASE; UNCLASSIFIED DRUG; VANADIC ACID;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARABIDOPSIS; ARTICLE; CONTROLLED STUDY; DNA REPAIR; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME STRUCTURE; KINETICS; MUTATION; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; PLANT GENE; PLANT GROWTH; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN HYDROLYSIS;

ACTIVE TRANSPORT, CELL NUCLEUS; AMINO ACID MOTIFS; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARABIDOPSIS; ARABIDOPSIS PROTEINS; CAMPTOTHECIN; CATALYTIC DOMAIN; CHLOROPHYLL; DNA REPAIR; KINETICS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; NUCLEAR LOCALIZATION SIGNALS; PHOSPHODIESTERASE INHIBITORS; PHOSPHORIC DIESTER HYDROLASES; PLANT LEAVES; SACCHAROMYCES CEREVISIAE; VANADATES;

ARABIDOPSIS; ARABIDOPSIS THALIANA;

EID: 84863372804     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20111308     Document Type: Article

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