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Volumn 40, Issue 4, 2012, Pages 1196-1202

Lewis Y regulates signaling molecules of the transforming growth factor β pathway in ovarian carcinoma-derived RMG-I cells

Author keywords

Lewis Y; P42 44 mitogen activated protein kinase; Phosphoinositide 3 kinase; Smad; Transforming growth factor type I (II) receptor

Indexed keywords

FUCOSYLTRANSFERASE; LEWIS Y; MITOGEN ACTIVATED PROTEIN KINASE; OLIGOSACCHARIDE; PHOSPHATIDYLINOSITOL 3 KINASE; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2; UNCLASSIFIED DRUG;

EID: 84863372049     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2011.1296     Document Type: Article
Times cited : (16)

References (44)
  • 1
    • 33645582453 scopus 로고    scopus 로고
    • Lewis(y) antigen (CD174) and apoptosis in gastric and colorectal carcinomas: Correlations with clinical and prognostic parameters
    • Baldus SE, Mönig SP, Zirbes TK, et al: Lewis(y) antigen (CD174) and apoptosis in gastric and colorectal carcinomas: correlations with clinical and prognostic parameters. Histol Histopathol 21: 503-510, 2006.
    • (2006) Histol Histopathol , vol.21 , pp. 503-510
    • Baldus, S.E.1    Mönig, S.P.2    Zirbes, T.K.3
  • 4
    • 33644874643 scopus 로고    scopus 로고
    • High expression of Lewis y/b antigens is associated with decreased survival in lymph node negative breast carcinomas
    • Madjd Z, Parsons T, Watson NF, Spendlove I, Ellis I and Durrant LG: High expression of Lewis y/b antigens is associated with decreased survival in lymph node negative breast carcinomas. Breast Cancer Res 7: R780-R787, 2005.
    • (2005) Breast Cancer Res , vol.7
    • Madjd, Z.1    Parsons, T.2    Watson, N.F.3    Spendlove, I.4    Ellis, I.5    Durrant, L.G.6
  • 5
    • 14144255432 scopus 로고    scopus 로고
    • Alterations in the glycolipid composition and cellular properties of ovarian carcinoma-derived RMG-1 cells on transfection of the α1,2-fucosyltransferase gene
    • DOI 10.1111/j.1349-7006.2005.00005.x
    • Iwamori M, Tanaka K, Kubushiro K, et al: Alterations in the glycolipid composition and cellular properties of ovarian carcinoma-derived RMG-1 cells on transfection of the α1,2-fucosyltransferase gene. Cancer Sci 96: 26-30, 2005. (Pubitemid 40310021)
    • (2005) Cancer Science , vol.96 , Issue.1 , pp. 26-30
    • Iwamori, M.1    Tanaka, K.2    Kubushiro, K.3    Lin, B.4    Kiguchi, K.5    Ishiwata, I.6    Tsukazaki, K.7    Nozawa, S.8
  • 6
    • 48049109380 scopus 로고    scopus 로고
    • Transfection of α1,2-fucosyltransferase gene increases the antigenic expression of Lewis y in ovarian cancer cell line RMG-I
    • Lin B, Hao YY, Wang DD, Zhu LC, Zhang SL, Saito M and Iwamori M: Transfection of α1,2-fucosyltransferase gene increases the antigenic expression of Lewis y in ovarian cancer cell line RMG-I. Acta Acad Med Sin 30: 284-289, 2008.
    • (2008) Acta Acad Med Sin , vol.30 , pp. 284-289
    • Lin, B.1    Hao, Y.Y.2    Wang, D.D.3    Zhu, L.C.4    Zhang, S.L.5    Saito, M.6    Iwamori, M.7
  • 7
    • 62249215808 scopus 로고    scopus 로고
    • Alpha1,2-fucosyltransferase gene transfection influences on biological behavior of ovarian carcinoma-derived RMG-I cells
    • Hao YY, Lin B, Zhao Y, et al: Alpha1,2-fucosyltransferase gene transfection influences on biological behavior of ovarian carcinoma-derived RMG-I cells. Fen Zi Xi Bao Sheng Wu Xue Bao 41: 435-442, 2008.
    • (2008) Fen Zi Xi Bao Sheng Wu Xue Bao , vol.41 , pp. 435-442
    • Hao, Y.Y.1    Lin, B.2    Zhao, Y.3
  • 8
    • 74849108223 scopus 로고    scopus 로고
    • Lewis y antigen promotes the proliferation of ovarian carcinoma-derived RMG-I cells through the PI3K/Akt signaling pathway
    • Liu J, Lin B, Hao Y, et al: Lewis y antigen promotes the proliferation of ovarian carcinoma-derived RMG-I cells through the PI3K/Akt signaling pathway. J Exp Clin Cancer Res 28: 154, 2009.
    • (2009) J Exp Clin Cancer Res , vol.28 , pp. 154
    • Liu, J.1    Lin, B.2    Hao, Y.3
  • 9
    • 77958121205 scopus 로고    scopus 로고
    • Lewis y promotes growth and adhesion of ovarian carcinoma-derived RMG-I cells by upregulating growth factors
    • Li F, Lin B, Hao Y, et al: Lewis y promotes growth and adhesion of ovarian carcinoma-derived RMG-I cells by upregulating growth factors. Int J Mol Sci 11: 3748-3759, 2010.
    • (2010) Int J Mol Sci , vol.11 , pp. 3748-3759
    • Li, F.1    Lin, B.2    Hao, Y.3
  • 11
    • 74849105124 scopus 로고    scopus 로고
    • Impact of α1,2-fucosyltransferase gene transfection on cancer-related gene expression profile of human ovarian cancer cell line RMG-1
    • Zhu LC, Lin B, Hao YY, Li FF, Diao B and Zhang SL: Impact of α1,2-fucosyltransferase gene transfection on cancer-related gene expression profile of human ovarian cancer cell line RMG-1. Ai Zheng 27: 934-941, 2008.
    • (2008) Ai Zheng , vol.27 , pp. 934-941
    • Zhu, L.C.1    Lin, B.2    Hao, Y.Y.3    Li, F.F.4    Diao, B.5    Zhang, S.L.6
  • 12
    • 0023183073 scopus 로고
    • Presence of tumor-associated antigens in epidermal growth factor receptors from different human carcinomas
    • Basu A, Murthy U, Rodeck U, Herlyn M, Mattes L and Das M: Presence of tumor-associated antigens in epidermal growth factor receptors from different human carcinomas. Cancer Res 47: 2531-2536, 1987. (Pubitemid 17083135)
    • (1987) Cancer Research , vol.47 , Issue.10 , pp. 2531-2536
    • Basu, A.1    Murthy, U.2    Rodeck, U.3
  • 14
    • 0021365895 scopus 로고
    • Analysis of Campylobacter jejuni antigens with monoclonal antibodies
    • Kosunen TU, Bång BE and Hurme M: Analysis of Campylobacter jejuni antigens with monoclonal antibodies. J Clin Microbiol 19: 129-133, 1984. (Pubitemid 14183562)
    • (1984) Journal of Clinical Microbiology , vol.19 , Issue.2 , pp. 129-133
    • Kosunen, T.U.1    Bang, B.E.2    Hurme, M.3
  • 15
    • 0019427030 scopus 로고
    • Studies of monoclonal and polyclonal anti-digoxin antibodies for serum digoxin radioimmunoassay
    • Bång BE, Hurme M, Juntunen K and Mäkelä O: Studies of monoclonal and polyclonal anti-digoxin antibodies for serum digoxin radioimmunoassay. Scand J Clin Lab Invest 41: 75-78, 1981.
    • (1981) Scand J Clin Lab Invest , vol.41 , pp. 75-78
    • Bång, B.E.1    Hurme, M.2    Juntunen, K.3    Mäkelä, O.4
  • 16
    • 0037155138 scopus 로고    scopus 로고
    • Y expression by H. pylori lipopolysaccharides
    • DOI 10.1074/jbc.M108574200
    • Moran AP, Knirel YA, Senchenkova SN, Widmalm G, Hynes SO and Jansson PE: Phenotypic variation in molecular mimicry between Helicobacter pylori lipopolysaccharides and human gastric epithelial cell surface glycoforms. Acid-induced phase variation in Lewisx and Lewisy expression by H. pylori lipopolysaccharides. J Biol Chem 277: 5785-5795, 2002. (Pubitemid 34968356)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.8 , pp. 5785-5795
    • Moran, A.P.1    Knirel, Y.A.2    Senchenkova, S.N.3    Widmalm, G.4    Hynes, S.O.5    Jansson, P.-E.6
  • 17
    • 0035710746 scopus 로고    scopus 로고
    • -ΔΔCT method
    • DOI 10.1006/meth.2001.1262
    • Livak KJ and Schmittgen TD: Analysis of relative gene expression data using real-time quantitative PCR and the 2-ΔΔCT method. Methods 25: 402-408, 2001. (Pubitemid 34164012)
    • (2001) Methods , vol.25 , Issue.4 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 18
    • 0037099745 scopus 로고    scopus 로고
    • TGF-β receptor-activated p38 MAP kinase mediates smad-independent TGF-β responses
    • DOI 10.1093/emboj/cdf366
    • Yu L, Hebert MC and Zhang YE: TGF-β receptor-activated p38 MAP kinase mediates Smad-independent TGF-β responses. EMBO J 21: 3749-3759, 2002. (Pubitemid 34787048)
    • (2002) EMBO Journal , vol.21 , Issue.14 , pp. 3749-3759
    • Yu, L.1    Hebert, M.C.2    Zhang, Y.E.3
  • 19
    • 0142104985 scopus 로고    scopus 로고
    • Smad-dependent and Smad-independent pathways in TGF-β family signalling
    • DOI 10.1038/nature02006
    • Derynck R and Zhang YE: Smad-dependent and Smad-independent pathways in TGF-β family signaling. Nature 425: 577-584, 2003. (Pubitemid 37280136)
    • (2003) Nature , vol.425 , Issue.6958 , pp. 577-584
    • Derynck, R.1    Zhang, Y.E.2
  • 20
    • 28544450380 scopus 로고    scopus 로고
    • Transforming growth factor-β activation of phosphatidylinositol 3-kinase is independent of Smad2 and Smad3 and regulates fibroblast responses via p21-activated kinase-2
    • Wilkes MC, Mitchell H, Penheiter SG, et al: Transforming growth factor-β activation of phosphatidylinositol 3-kinase is independent of Smad2 and Smad3 and regulates fibroblast responses via p21-activated kinase-2. Cancer Res 65: 10431.-10440, 2005.
    • (2005) Cancer Res , vol.65
    • Wilkes, M.C.1    Mitchell, H.2    Penheiter, S.G.3
  • 21
    • 58149213801 scopus 로고    scopus 로고
    • Non-Smad pathways in TGF-β signaling
    • Zhang YE: Non-Smad pathways in TGF-β signaling. Cell Res 19: 128-139, 2009.
    • (2009) Cell Res , vol.19 , pp. 128-139
    • Zhang, Y.E.1
  • 22
    • 0035153463 scopus 로고    scopus 로고
    • Role of transforming growth factor beta in cancer
    • Pasche B: Role of transforming growth factor beta in cancer. J Cell Physiol 186: 153-168, 2001.
    • (2001) J Cell Physiol , vol.186 , pp. 153-168
    • Pasche, B.1
  • 23
    • 15744372725 scopus 로고    scopus 로고
    • Role of transforming growth factor beta in human cancer
    • DOI 10.1200/JCO.2005.02.047
    • Elliott RL and Blobe GC: Role of transforming growth factor beta in human cancer. J Clin Oncol 23: 2078-2093, 2005. (Pubitemid 46211385)
    • (2005) Journal of Clinical Oncology , vol.23 , Issue.9 , pp. 2078-2093
    • Elliott, R.L.1    Blobe, G.C.2
  • 24
    • 66349135076 scopus 로고    scopus 로고
    • The TGF-β paradox in human cancer: An update
    • Tian M and Schiemann WP: The TGF-β paradox in human cancer: an update. Future Oncol 5: 259-271, 2009.
    • (2009) Future Oncol , vol.5 , pp. 259-271
    • Tian, M.1    Schiemann, W.P.2
  • 25
    • 0027421280 scopus 로고
    • Resistance to inhibition of cell growth by transforming growth factor-beta and its role in oncogenesis
    • Fynan TM and Reiss M: Resistance to inhibition of cell growth by transforming growth factor-beta and its role in oncogenesis. Crit Rev Oncol 4: 493-540, 1993.
    • (1993) Crit Rev Oncol , vol.4 , pp. 493-540
    • Fynan, T.M.1    Reiss, M.2
  • 26
    • 0034644472 scopus 로고    scopus 로고
    • TGFβ signaling in growth control, cancer, and heritable disorders
    • Massague J, Blain SW and Lo RS: TGFβ signaling in growth control, cancer, and heritable disorders. Cell 103: 295-309, 2000.
    • (2000) Cell , vol.103 , pp. 295-309
    • Massague, J.1    Blain, S.W.2    Lo, R.S.3
  • 27
    • 0032848011 scopus 로고    scopus 로고
    • Ovarian carcinoma cell cultures are resistant to TGF-β1-mediated growth inhibition despite expression of functional receptors
    • Yamada SD, Baldwin RL and Karlan BY: Ovarian carcinoma cell cultures are resistant to TGF-β1-mediated growth inhibition despite expression of functional receptors. Gynecol Oncol 75: 72.-77, 1999.
    • (1999) Gynecol Oncol , vol.75
    • Yamada, S.D.1    Baldwin, R.L.2    Karlan, B.Y.3
  • 28
    • 0034009725 scopus 로고    scopus 로고
    • Anomalies of the TGF-beta postreceptor signaling pathway in ovarian cancer cell lines
    • Hu W, Wu W, Nash MA, Freedman RS, Kavanagh JJ and Verschraegen CF: Anomalies of the TGF-beta postreceptor signaling pathway in ovarian cancer cell lines. Anticancer Res 20: 729-733, 2000. (Pubitemid 30240626)
    • (2000) Anticancer Research , vol.20 , Issue.2 A , pp. 729-733
    • Hu, W.1    Wu, W.2    Nash, M.A.3    Freedman, R.S.4    Kavanagh, J.J.5    Verschraegen, C.F.6
  • 29
    • 0030793369 scopus 로고    scopus 로고
    • Expression of transforming growth factor β type II receptor reduces tumorigenicity in human gastric cancer cells
    • Chang J, Park K, Bang YJ, Kim WS, Kim D and Kim SJ: Expression of transforming growth factor β type II receptor reduces tumorigenicity in human gastric cancer cells. Cancer Res 57: 2856-2859, 1997. (Pubitemid 27315027)
    • (1997) Cancer Research , vol.57 , Issue.14 , pp. 2856-2859
    • Chang, J.1    Park, K.2    Bang, Y.-J.3    Kim, W.S.4    Kim, D.5    Kim, S.-J.6
  • 30
    • 0032527902 scopus 로고    scopus 로고
    • Mutation of the type II transforming growth factor-β receptor is coincident with the transformation of human colon adenomas to malignant carcinomas
    • Grady WM, Rajput A, Myeroff L, Liu DF, Kwon K, Willis J and Markowitz S: Mutation of the type II transforming growth factor-β receptor is coincident with the transformation of human colon adenomas to malignant carcinomas. Cancer Res 58: 3101.-3104, 1998.
    • (1998) Cancer Res , vol.58
    • Grady, W.M.1    Rajput, A.2    Myeroff, L.3    Liu, D.F.4    Kwon, K.5    Willis, J.6    Markowitz, S.7
  • 31
    • 0030593038 scopus 로고    scopus 로고
    • DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1
    • Hahn SA, Schutte M, Hoque AT, et al: DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1. Science 271: 350-353, 1996.
    • (1996) Science , vol.271 , pp. 350-353
    • Hahn, S.A.1    Schutte, M.2    Hoque, A.T.3
  • 33
    • 16044369574 scopus 로고    scopus 로고
    • MADR2 maps to 18q21 and encodes a TGFβ-regulated MAD-related protein that is functionally mutated in colorectal carcinoma
    • Eppert K, Scherer SW, Ozcelik H, et al: MADR2 maps to 18q21 and encodes a TGFβ-regulated MAD-related protein that is functionally mutated in colorectal carcinoma. Cell 86: 543.-552, 1996.
    • (1996) Cell , vol.86
    • Eppert, K.1    Scherer, S.W.2    Ozcelik, H.3
  • 34
    • 0033227597 scopus 로고    scopus 로고
    • Mutation analysis of the smad3 gene in human ovarian cancers
    • Wang D, Kanuma T, Takama F, et al: Mutation analysis of the smad3 gene in human ovarian cancers. Int J Oncol 15: 949.-953, 1999.
    • (1999) Int J Oncol , vol.15
    • Wang, D.1    Kanuma, T.2    Takama, F.3
  • 35
    • 0030849060 scopus 로고    scopus 로고
    • Mutation analysis of the transforming growth factor-β type II receptor in human cell lines resistant to growth inhibition by transforming growth factor-β
    • Vincent F, Nagashima M, Takenoshita S, Khan MA, Gemma A, Hagiwara K and Bennett WP: Mutation analysis of the transforming growth factor-β type II receptor in human cell lines resistant to growth inhibition by transforming growth factor-β. Oncogene 15: 117-122, 1997. (Pubitemid 27348103)
    • (1997) Oncogene , vol.15 , Issue.1 , pp. 117-122
    • Vincent, F.1    Nagashima, M.2    Takenoshita, S.3    Khan, M.A.4    Gemma, A.5    Hagiwara, K.6    Bennett, W.P.7
  • 36
    • 0034544259 scopus 로고    scopus 로고
    • Mutation analysis of the Smad6 and Smad7 gene in human ovarian cancers
    • Wang D, Kanuma T, Mizumuma H, Ibuki Y and Takenoshita S: Mutation analysis of the Smad6 and Smad7 gene in human ovarian cancers. Int J Oncol 17: 1087-1091, 2000.
    • (2000) Int J Oncol , vol.17 , pp. 1087-1091
    • Wang, D.1    Kanuma, T.2    Mizumuma, H.3    Ibuki, Y.4    Takenoshita, S.5
  • 37
    • 0033779764 scopus 로고    scopus 로고
    • Activation-dependent expression of the blood group-related lewis Y antigen on peripheral blood granulocytes
    • Dettke M, Palfi G and Loibner H: Activation-dependent expression of the blood group-related lewis Y antigen on peripheral blood granulocytes. J Leukoc Biol 68: 511-514, 2000.
    • (2000) J Leukoc Biol , vol.68 , pp. 511-514
    • Dettke, M.1    Palfi, G.2    Loibner, H.3
  • 38
    • 33751165070 scopus 로고    scopus 로고
    • Inhibition of xenograft tumor growth and down-regulation of ErbB receptors by an antibody directed against Lewis Y antigen
    • Farhan H, Schuster C, Klinger M, et al: Inhibition of xenograft tumor growth and down-regulation of ErbB receptors by an antibody directed against Lewis Y antigen. J Pharmacol Exp Ther 319: 1459-1466, 2006.
    • (2006) J Pharmacol Exp Ther , vol.319 , pp. 1459-1466
    • Farhan, H.1    Schuster, C.2    Klinger, M.3
  • 39
    • 33846027447 scopus 로고    scopus 로고
    • Alpha 1,3-fucosyltransferase-VII regulates the signaling molecules of the insulin receptor pathway
    • DOI 10.1111/j.1742-4658.2006.05599.x
    • Wang QY, Zhang Y, Chen HJ, Shen ZH and Chen HL: Alpha 1,3-fucosyltransferase-VII regulates the signaling molecules of the insulin receptor pathway. FEBS J 274: 526-538, 2007. (Pubitemid 46046660)
    • (2007) FEBS Journal , vol.274 , Issue.2 , pp. 526-538
    • Wang, Q.-Y.1    Zhang, Y.2    Chen, H.-J.3    Shen, Z.-H.4    Chen, H.-L.5
  • 40
    • 0242497921 scopus 로고    scopus 로고
    • HER2/Neu- and TAK1-mediated Up-regulation of the Transforming Growth Factor β Inhibitor Smad7 via the ETS Protein ER81
    • DOI 10.1074/jbc.M307202200
    • Dowdy SC, Mariani A and Janknecht R: HER2/Neu- and TAK1-mediated up-regulation of the transforming growth factor β inhibitor Smad7 via the ETS protein ER81. J Biol Chem 278: 44377-44384, 2003. (Pubitemid 37377186)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.45 , pp. 44377-44384
    • Dowdy, S.C.1    Mariani, A.2    Janknecht, R.3
  • 42
    • 0037326526 scopus 로고    scopus 로고
    • Transforming growth factor-β1 (TGF-β)-induced apoptosis of prostate cancer cells involves Smad7-dependent activation of p38 by TGF-β-activated kinase 1 and mitogen-activated protein kinase kinase 3
    • DOI 10.1091/mbc.02-03-0037
    • Edlund S, Bu S, Schuster N, et al: Transforming growth factor-β1 (TGF-β)-induced apoptosis of prostate cancer cells involves Smad7-dependent activation of p38 by TGF-β-activated kinase 1 and mitogen-activated protein kinase kinase 3. Mol Biol Cell 14: 529-544, 2003. (Pubitemid 36237014)
    • (2003) Molecular Biology of the Cell , vol.14 , Issue.2 , pp. 529-544
    • Edlund, S.1    Bu, S.2    Schuster, N.3    Aspenstrom, P.4    Heuchel, R.5    Heldin, N.-E.6    Ten, D.P.7    Heldin, C.-H.8    Landstrom, M.9
  • 43
    • 55249108036 scopus 로고    scopus 로고
    • Smad7 inhibits chondrocyte differentiation at multiple steps during endochondral bone formation and down-regulates p38 MAPK pathways
    • Iwai T, Murai J, Yoshikawa H and Tsumaki N: Smad7 inhibits chondrocyte differentiation at multiple steps during endochondral bone formation and down-regulates p38 MAPK pathways. J Biol Chem 283: 27154-27164, 2008.
    • (2008) J Biol Chem , vol.283 , pp. 27154-27164
    • Iwai, T.1    Murai, J.2    Yoshikawa, H.3    Tsumaki, N.4
  • 44
    • 0035965344 scopus 로고    scopus 로고
    • Evidence for a role of the JNK cascade in Smad7-mediated apoptosis
    • Mazars A, Lallemand F, Prunier C, et al: Evidence for a role of the JNK cascade in Smad7-mediated apoptosis. J Biol Chem 276: 36797-36803, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 36797-36803
    • Mazars, A.1    Lallemand, F.2    Prunier, C.3


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