n - 3 polyunsaturated fatty acids suppress phosphatidylinositol 4,5-bisphosphate-dependent actin remodelling during CD4 + T-cell activation

Biochemical Journal

Volumn 443, Issue 1, 2012, Pages 27-37

  Hou, Tim Y ^a   Monk, Jennifer M ^a   Fan, Yang Yi ^a   Barhoumi, Rola ^a,b   Chen, Yong Q ^c   Rivera, Gonzalo M ^b   Mcmurray, David N ^a,b   Chapkin, Robert S ^a,b  

^a TEXAS A AND M UNIVERSITY   (United States)

^b TEXAS A AND M UNIVERSITY   (United States)

^c WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

Actin remodelling; Immunological synapse; N 3 polyunsaturated fatty acid; PtdIns(4,5)P 2; T cell activation; Wiskott Aldrich syndrome protein

Indexed keywords

4 METHOXYAMPHETAMINE; ACTIN; CD3 ANTIBODY; DOCOSAHEXAENOIC ACID; IONOMYCIN; MONOCLONAL ANTIBODY CD28; NEURAL WISKOTT ALDRICH SYNDROME PROTEIN; OMEGA 3 FATTY ACID; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; TRIACYLGLYCEROL;

ACTIN POLYMERIZATION; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CD4+ T LYMPHOCYTE; CELL ISOLATION; CELL MEMBRANE; CELL STIMULATION; CONTROLLED STUDY; DIET; FEEDING; GENE REPRESSION; IMMUNOLOGICAL SYNAPSE; INCUBATION TIME; LIPID RAFT; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN METABOLISM; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION; TRANSGENIC ANIMAL;

ACTIN CYTOSKELETON; ANIMALS; ANTI-INFLAMMATORY AGENTS; CADHERINS; CD4-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; FATTY ACIDS, OMEGA-3; IMMUNOLOGICAL SYNAPSES; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; PHOSPHATIDYLINOSITOL 4,5-DIPHOSPHATE; PROTEIN TRANSPORT; SPLEEN; WISKOTT-ALDRICH SYNDROME PROTEIN;

MUS; MUS MUSCULUS;

EID: 84863338140     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20111589     Document Type: Article

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