An extracellular MRI polymeric contrast agent that degrades at physiological pH

Molecular Pharmaceutics

Volumn 9, Issue 7, 2012, Pages 1911-1918

  Schopf, Eric ^a,c   Sankaranarayanan, Jagadis ^a   Chan, Minnie ^b   Mattrey, Robert ^b   Almutairi, Adah ^a,b  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c Librede Inc   (United States)

Author keywords

bioresponsive; contrast agents; extracellular degradation; Gd(III) complexes; polyketal

Indexed keywords

CONTRAST MEDIUM; GADOLINIUM; GADOLINIUM PENTETATE; POLYMER;

ARTICLE; BIODEGRADATION; CHELATION; CONCENTRATION (PARAMETERS); CONTRAST ENHANCEMENT; FRAGMENTATION REACTION; HYDROLYSIS; IN VITRO STUDY; KIDNEY CLEARANCE; MOLECULAR WEIGHT; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PH; PRIORITY JOURNAL; SYNTHESIS;

ANIMALS; CONTRAST MEDIA; FEMALE; GADOLINIUM; GADOLINIUM DTPA; HYDROGEN-ION CONCENTRATION; HYDROLYSIS; MAGNETIC RESONANCE IMAGING; MICE; MOLECULAR WEIGHT; POLYMERS;

EID: 84863330661     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp2005998     Document Type: Article

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