Multiresponse strategies to modulate burst degradation and release from nanoparticles

ACS Nano

Volumn 4, Issue 10, 2010, Pages 5930-5936

  Sankaranarayanan, Jagadis ^a   Mahmoud, Enas A ^a   Kim, Gloria ^a   Morachis, José M ^a   Almutairi, Adah ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

burst release; dual pH response polymers; logic gate; nanoparticles; poly aminoester ketal

Indexed keywords

ACID-CATALYZED HYDROLYSIS; BURST RELEASE; CHEMICAL TRANSFORMATIONS; DIACRYLATES; DISEASED TISSUES; KETAL MOIETY; MULTIRESPONSE; OIL-IN-WATER EMULSIONS; PH RANGE; PH RESPONSE; PH-RESPONSIVE; POLYMERIC NANOPARTICLES; RAPID DEGRADATION; TRIMETHYLENE;

ACIDS; DEGRADATION; EMULSIFICATION; ETHANE; HEXANE; LOGIC GATES; NANOPARTICLES; PH SENSORS; PROPANE;

POLYMERS;

ESTER; NANOPARTICLE; POLYMER; TETRAZOLIUM; THIAZOLE DERIVATIVE; THIAZOLYL BLUE;

ANIMAL; ARTICLE; CELL CULTURE; CELL LINE; CHEMICAL MODEL; CHEMISTRY; INFLAMMATION; LIGHT; MATERIALS TESTING; METHODOLOGY; MOUSE; NANOTECHNOLOGY; PH; RADIATION SCATTERING; SOLUBILITY; SURFACE PROPERTY;

ANIMALS; CELL LINE; CELLS, CULTURED; ESTERS; HYDROGEN-ION CONCENTRATION; INFLAMMATION; LIGHT; MATERIALS TESTING; MICE; MODELS, CHEMICAL; NANOPARTICLES; NANOTECHNOLOGY; POLYMERS; SCATTERING, RADIATION; SOLUBILITY; SURFACE PROPERTIES; TETRAZOLIUM SALTS; THIAZOLES;

EID: 78049326922     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/nn100968e     Document Type: Article

References (40)

1. Farokhzad, O. C.; Karp, J. M.; Langer, R. Nanoparticle-Aptamer Bioconjugates for Cancer Targeting Expert Opin. Drug Delivery 2006, 3, 311-324
2. Farokhzad, O. C.; Langer, R. Impact of Nanotechnology on Drug Delivery ACS Nano 2009, 3, 16-20
3. Ferrari, M. Cancer Nanotechnology: Opportunities and Challenges Nat. Rev. Cancer 2005, 5, 161-171
4. Ganta, S.; Devalapally, H.; Shahiwala, A.; Amiji, M. A Review of Stimuli-Responsive Nanocarriers for Drug and Gene Delivery J. Controlled Release 2008, 126, 187-204
5. Langer, R. New Methods of Drug Delivery Science 1990, 249, 1527-1533
6. LaVan, D. A.; McGuire, T.; Langer, R. Small-Scale Systems for in Vivo Drug Delivery Nat. Biotechnol. 2003, 21, 1184-1191
7. Whitesides, G. M. The "Right" Size in Nanobiotechnology Nat. Biotechnol. 2003, 21, 1161-1165
8. Zhang, L.; Gu, F. X.; Chan, J. M.; Wang, A. Z.; Langer, R. S.; Farokhzad, O. C. Nanoparticles in Medicine: Therapeutic Applications and Developments Clin. Pharm. Ther. 2008, 83, 761-769
9. Tewes, F.;; Boury, F.;; Benoit, J. Biodegradable Microspheres: Advances in Production Technology. Microencapsulation: Methods and Industrial Applications
10. Benita, S., Ed.; Taylor and Francis: New York, 2006; pp 1 - 41; (Drugs Pharm. Sci. 2006, 158).
11. Almutairi, A.; Akers, W. J.; Berezin, M. Y.; Achilefu, S.; Frechet, J. M. J. Monitoring the Biodegradation of Dendritic Near-Infrared Nanoprobes by in Vivo Fluorescence Imaging Mol. Pharm. 2008, 5, 1103-1110
12. Lewis, D. H.: Controlled Release of Bioactive Agents from Lactide/Glycolide Polymers. Biodegradable Polymers as Drug Delivery Systems; Drugs and the Pharmaceutical Sciences, Vol. 45, Chasin, M.; Langer, R., Eds.; Marcel Dekker: New York, 1990; pp 1 - 42.
13. Panyam, J.; Labhasetwar, V. Biodegradable Nanoparticles for Drug and Gene Delivery to Cells and Tissue Adv. Drug Delivery. Rev. 2003, 55, 329-347
14. Shenoy, D.; Little, S.; Langer, R.; Amiji, M. Poly(ethylene oxide)-Modified Poly(beta-amino ester) Nanoparticles as a pH-Sensitive System for Tumor-Targeted Delivery of Hydrophobic Drugs: Part 2. In Vivo Distribution and Tumor Localization Studies Pharm. Res. 2005, 22, 2107-2114
15. Vasir, J. K.; Labhasetwar, V. Biodegradable Nanoparticles for Cytosolic Delivery of Therapeutics Adv. Drug Delivery. Rev. 2007, 59, 718-728
16. Mescalchin, A.; Detzer, A.; Wecke, M.; Overhoff, M.; Wuensche, W.; Sczakiel, G. Cellular Uptake and Intracellular Release are Major Obstacles to the Therapeutic Application of siRNA: Novel Options by Phosphorothioate- Stimulated Delivery Expert Opin. Biol. Ther. 2007, 7, 1531-1538
17. Sonawane, N. D.; Szoka, F. C., Jr.; Verkman, A. S. Chloride Accumulation and Swelling in Endosomes Enhances DNA Transfer by Polyamine-DNA Polyplexes J. Biol. Chem. 2003, 278, 44826-44831
18. Hu, Y.; Litwin, T.; Nagaraja, A. R.; Kwong, B.; Katz, J.; Watson, N.; Irvine, D. J. Cytosolic Delivery of Membrane-Impermeable Molecules in Dendritic Cells Using pH-Responsive Core-Shell Nanoparticles Nano Lett. 2007, 7, 3056-3064
19. Cohen, J. L.; Almutairi, A.; Cohen, J. A.; Bernstein, M.; Brody, S. L.; Schuster, D. P.; Frechet, J. M. Enhanced Cell Penetration of Acid-Degradable Particles Functionalized with Cell-Penetrating Peptides Bioconjugate Chem. 2008, 19, 876-881
20. Yang, S. C.; Bhide, M.; Crispe, I. N.; Pierce, R. H.; Murthy, N. Polyketal Copolymers: A New Acid-Sensitive Delivery Vehicle for Treating Acute Inflammatory Diseases Bioconjugate Chem. 2008, 19, 1164-1169
21. Heffernan, M. J.; Kasturi, S. P.; Yang, S. C.; Pulendran, B.; Murthy, N. The Stimulation of CD8+ T Cells by Dendritic Cells Pulsed with Polyketal Microparticles Containing Ion-Paired Protein Antigen and Poly(inosinic acid)-Poly(cytidylic acid) Biomaterials 2009, 30, 910-918
22. Heffernan, M. J.; Murthy, N. Polyketal Nanoparticles: A New pH-Sensitive Biodegradable Drug Delivery Vehicle Bioconjugate Chem. 2005, 16, 1340-1342
23. Paramonov, S. E.; Bachelder, E. M.; Beaudette, T. T.; Standley, S. M.; Lee, C. C.; Dashe, J.; Frechet, J. M. J. Fully Acid-Degradable Biocompatible Polyacetal Microparticles for Drug Delivery Bioconjugate Chem. 2008, 19, 911-919
24. Akinc, A.; Anderson, D. G.; Lynn, D. M.; Langer, R. Synthesis of Poly(beta-amino ester)s Optimized for Highly Effective Gene Delivery Bioconjugate Chem. 2003, 14, 979-988
25. Kohane, D. S.; Tse, J. Y.; Yeo, Y.; Padera, R.; Shubina, M.; Langer, R. Biodegradable Polymeric Microspheres and Nanospheres for Drug Delivery in the Peritoneum J. Biomed. Mater. Res., A 2006, 77, 351-361
26. Lynn, D. M.; Amiji, M. M.; Langer, R. pH-Responsive Polymer Microspheres: Rapid Release of Encapsulated Material within the Range of Intracellular pH Angew. Chem., Int. Ed. 2001, 40, 1707-1710
27. Lynn, D. M.; Anderson, D. G.; Putnam, D.; Langer, R. Accelerated Discovery of Synthetic Transfection Vectors: Parallel Synthesis and Screening of a Degradable Polymer Library J. Am. Chem. Soc. 2001, 123, 8155-8156
28. Lynn, D. M.; Langer, R. Degradable Poly(β-amino esters): Synthesis, Characterization, and Self-Assembly with Plasmid DNA J. Am. Chem. Soc. 2000, 122, 10761-10768
29. Anderson, D. G.; Lynn, D. M.; Langer, R. Semi-automated Synthesis and Screening of a Large Library of Degradable Cationic Polymers for Gene Delivery Angew. Chem., Int. Ed. 2003, 42, 3153-3158
30. Hofmann, D.; Entrialgo-Castano, M.; Kratz, K.; Lendlein, A. Knowledge-Based Approach towards Hydrolytic Degradation of Polymer-Based Biomaterials Adv. Mater. 2009, 21, 3237-3245
31. Smith, R. C.; Leung, A.; Kim, B.-S.; Hammond, P. T. Hydrophobic Effects in the Critical Destabilization and Release Dynamics of Degradable Multilayer Films Chem. Mater. 2009, 21, 1108-1115
32. Zhang, J.; Fredin, N. J.; Janz, J. F.; Sun, B.; Lynn, D. M. Structure/Property Relationships in Erodible Multilayered Films: Influence of Polycation Structure on Erosion Profiles and the Release of Anionic Polyelectrolytes Langmuir 2006, 22, 239-245
33. Zhong, Z.; Song, Y.; Engbersen, J. F. J.; Lok, M. C.; Hennink, W. E.; Feijen, J. A Versatile Family of Degradable Non-viral Gene Carriers Based on Hyperbranched Poly(ester amine)s J. Controlled Release 2005, 109, 317-329
34. Broaders Kyle, E.; Cohen Joel, A.; Beaudette Tristan, T.; Bachelder Eric, M.; Frechet Jean, M. J. Acetalated Dextran is a Chemically and Biologically Tunable Material for Particulate Immunotherapy Proc. Natl. Acad. Sci. U.S.A. 2009, 106, 5497-5502
35. Jain, R.; Standley, S. M.; Frechet, J. M. J. Synthesis and Degradation of pH-Sensitive Linear Poly(amidoamine)s Macromolecules 2007, 40, 452-457
36. Kim, M. S.; Hwang, S. J.; Han, J. K.; Choi, E. K.; Park, H. J.; Kim, J. S.; Lee, D. S. pH-Responsive PEG-poly(beta-amino ester) Block Copolymer Micelles with a Sharp Transition Macromol. Rapid Commun. 2006, 27, 447-451
37. Kim, M. S.; Lee, D. S.; Choi, E.-K.; Park, H.-J.; Kim, J.-S. Modulation of Poly(beta-amino ester) pH-Sensitive Polymers by Molecular Weight Control Macromol. Res. 2005, 13, 147-151
38. Reineke, T. M. Poly(glycoamidoamine)s: Cationic Glycopolymers for DNA Delivery J. Polym. Sci., Part A 2006, 44, 6895-6908
39. Heath, W. H.; Palmieri, F.; Adams, J. R.; Long, B. K.; Chute, J.; Holcombe, T. W.; Zieren, S.; Truitt, M. J.; White, J. L.; Willson, C. G. Degradable Crosslinkers and Strippable Imaging Materials for Step-and-Flash Imprint Lithography Macromolecules 2008, 41, 719-726
40. Dalwadi, G.; Benson, H.; Chen, Y. Comparison of Diafiltration and Tangential Flow Filtration for Purification of Nanoparticle Suspensions Pharm. Res. 2005, 22, 2152-2162