High molecular weight hyaluronan reduces lipopolysaccharide mediated microglial activation

Journal of Neurochemistry

Volumn 122, Issue 2, 2012, Pages 344-355

  Austin, James W ^a,b   Gilchrist, Chris ^a,b   Fehlings, Michael G ^a,b  

^a UNIVERSITY OF TORONTO   (Canada)

^b TORONTO WESTERN HOSPITAL   (Canada)

Author keywords

hyaluronan; inflammation; LPS; microglia; TLR4

Indexed keywords

A20 PROTEIN; ANTIINFLAMMATORY AGENT; HYALURONIC ACID; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; NITRIC OXIDE; PROTEIN KINASE B; REGULATOR PROTEIN; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL ACTIVATION; CELL CULTURE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; FEMALE; GENE; GENE EXPRESSION; IL 1BETA GENE; IL 6 GENE; MICROGLIA; MOLECULAR WEIGHT; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR ALPHA GENE;

ANIMALS; ANTI-INFLAMMATORY AGENTS; BLOTTING, WESTERN; CELLS, CULTURED; DNA; DNA-BINDING PROTEINS; ENZYME-LINKED IMMUNOSORBENT ASSAY; HYALURONIC ACID; IMMUNOHISTOCHEMISTRY; INFLAMMATION; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; MACROPHAGE ACTIVATION; MICROGLIA; MITOGEN-ACTIVATED PROTEIN KINASES; MOLECULAR WEIGHT; NITRIC OXIDE; ONCOGENE PROTEIN V-AKT; PHOSPHORYLATION; RATS; REAL-TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4;

RATTUS;

EID: 84863327960     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2012.07789.x     Document Type: Article

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