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Volumn 18, Issue , 2012, Pages 1238-1246

Downregulation of transforming growth factor-β type II receptor prohibit epithelial-to-mesenchymal transition in lens epithelium

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; FIBRONECTIN; SMALL INTERFERING RNA; TRANSFORMING GROWTH FACTOR; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2;

EID: 84863322013     PISSN: None     EISSN: 10900535     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (16)

References (45)
  • 1
    • 0042622210 scopus 로고    scopus 로고
    • Epithelial transdifferentiation and cataract in the human lens
    • [PMID: 12907166]
    • Marcantonio JM, Syam PP, Liu CS, Duncan G. Epithelial transdifferentiation and cataract in the human lens. Exp Eye Res 2003; 77:339-46. [PMID: 12907166]
    • (2003) Exp Eye Res , vol.77 , pp. 339-346
    • Marcantonio, J.M.1    Syam, P.P.2    Liu, C.S.3    Duncan, G.4
  • 2
    • 67650999875 scopus 로고    scopus 로고
    • The basics of epithelial-mesenchymal transition
    • [PMID: 19487818]
    • Kalluri R, Weinberg RA. The basics of epithelial-mesenchymal transition. J Clin Invest 2009; 119:1420-8. [PMID: 19487818]
    • (2009) J Clin Invest , vol.119 , pp. 1420-1428
    • Kalluri, R.1    Weinberg, R.A.2
  • 4
    • 0032033167 scopus 로고    scopus 로고
    • Immunolocalization of prolyl 4-hydroxylase subunits, alpha-smooth muscle actin, and extracellular matrix components in human lens capsules with lens implants
    • [PMID: 9533856]
    • Saika S, Kawashima Y, Miyamoto T, Okada Y, Tanaka SI, Ohmi S, Minamide A, Yamanaka O, Ohnishi Y, Ooshima A, Yamanaka A. Immunolocalization of prolyl 4-hydroxylase subunits, alpha-smooth muscle actin, and extracellular matrix components in human lens capsules with lens implants. Exp Eye Res 1998; 66:283-94. [PMID: 9533856]
    • (1998) Exp Eye Res , vol.66 , pp. 283-294
    • Saika, S.1    Kawashima, Y.2    Miyamoto, T.3    Okada, Y.4    Tanaka, S.I.5    Ohmi, S.6    Minamide, A.7    Yamanaka, O.8    Ohnishi, Y.9    Ooshima, A.10    Yamanaka, A.11
  • 5
    • 0028567054 scopus 로고
    • TGFbeta 1 induces lens cells to accumulate alpha-smooth muscle actin, a marker for subcapsular cataracts
    • [PMID: 7720396]
    • Hales AM, Schulz MW, Chamberlain CG, McAvoy JW. TGFbeta 1 induces lens cells to accumulate alpha-smooth muscle actin, a marker for subcapsular cataracts. Curr Eye Res 1994; 13:885-90. [PMID: 7720396]
    • (1994) Curr Eye Res , vol.13 , pp. 885-890
    • Hales, A.M.1    Schulz, M.W.2    Chamberlain, C.G.3    McAvoy, J.W.4
  • 6
    • 0031685620 scopus 로고    scopus 로고
    • TGF-beta signal transduction
    • [PMID: 9759503]
    • Massagué J. TGF-beta signal transduction. Annu Rev Biochem 1998; 67:753-91. [PMID: 9759503]
    • (1998) Annu Rev Biochem , vol.67 , pp. 753-791
    • Massagué, J.1
  • 7
    • 0034673972 scopus 로고    scopus 로고
    • Transforming growth factor beta signaling mediators and modulators
    • [PMID: 10831835]
    • Zimmerman CM, Padgett RW. Transforming growth factor beta signaling mediators and modulators. Gene 2000; 249:17-30. [PMID: 10831835]
    • (2000) Gene , vol.249 , pp. 17-30
    • Zimmerman, C.M.1    Padgett, R.W.2
  • 8
    • 0033932667 scopus 로고    scopus 로고
    • TGF-beta signaling by Smad proteins
    • [PMID: 10879283]
    • Miyazono K, ten Dijke P, Heldin CH. TGF-beta signaling by Smad proteins. Adv Immunol 2000; 75:115-57. [PMID: 10879283]
    • (2000) Adv Immunol , vol.75 , pp. 115-157
    • Miyazono, K.1    ten Dijke, P.2    Heldin, C.H.3
  • 9
    • 0029553183 scopus 로고
    • An overview of epithelio-mesenchymal transformation
    • [PMID: 8714286]
    • Hay ED. An overview of epithelio-mesenchymal transformation. Acta Anat (Basel) 1995; 154:8-20. [PMID: 8714286]
    • (1995) Acta Anat (Basel) , vol.154 , pp. 8-20
    • Hay, E.D.1
  • 10
    • 0034798707 scopus 로고    scopus 로고
    • Leaving the neighborhood: Molecular mechanisms involved during epithelial-mesenchymal transition
    • [PMID: 11598958]
    • Savagner P. Leaving the neighborhood: molecular mechanisms involved during epithelial-mesenchymal transition. Bioessays 2001; 23:912-23. [PMID: 11598958]
    • (2001) Bioessays , vol.23 , pp. 912-923
    • Savagner, P.1
  • 11
    • 0037013742 scopus 로고    scopus 로고
    • Mechanisms of TGF-beta signaling in regulation of cell growth and differentiation
    • [PMID: 12008039]
    • Moustakas A, Pardali K, Gaal A, Heldin CH. Mechanisms of TGF-beta signaling in regulation of cell growth and differentiation. Immunol Lett 2002; 82:85-91. [PMID: 12008039]
    • (2002) Immunol Lett , vol.82 , pp. 85-91
    • Moustakas, A.1    Pardali, K.2    Gaal, A.3    Heldin, C.H.4
  • 12
    • 0025043971 scopus 로고
    • Transforming growth factor-beta in human aqueous humor
    • [PMID: 2276273]
    • Jampel HD, Roche N, Stark WJ, Roberts AB. Transforming growth factor-beta in human aqueous humor. Curr Eye Res 1990; 9:963-9. [PMID: 2276273]
    • (1990) Curr Eye Res , vol.9 , pp. 963-969
    • Jampel, H.D.1    Roche, N.2    Stark, W.J.3    Roberts, A.B.4
  • 14
    • 0032547895 scopus 로고    scopus 로고
    • TGFbeta signaling is necessary for carcinoma cell invasiveness and metastasis
    • [PMID: 9822576]
    • Oft M, Heider KH, Beug H. TGFbeta signaling is necessary for carcinoma cell invasiveness and metastasis. Curr Biol 1998; 8:1243-52. [PMID: 9822576]
    • (1998) Curr Biol , vol.8 , pp. 1243-1252
    • Oft, M.1    Heider, K.H.2    Beug, H.3
  • 15
    • 0028603343 scopus 로고
    • TGF-beta induced transdifferentiation of mammary epithelial cells to mesenchymal cells: Involvement of type I receptors
    • [PMID: 7806579]
    • Miettinen PJ, Ebner R, Lopez AR, Derynck R. TGF-beta induced transdifferentiation of mammary epithelial cells to mesenchymal cells: involvement of type I receptors. J Cell Biol 1994; 127:2021-36. [PMID: 7806579]
    • (1994) J Cell Biol , vol.127 , pp. 2021-2036
    • Miettinen, P.J.1    Ebner, R.2    Lopez, A.R.3    Derynck, R.4
  • 16
    • 0034100613 scopus 로고    scopus 로고
    • Role of cytokines in the pathogenesis of posterior capsule opacification
    • [PMID: 10684849]
    • Meacock WR, Spalton DJ, Stanford MR. Role of cytokines in the pathogenesis of posterior capsule opacification. Br J Ophthalmol 2000; 84:332-6. [PMID: 10684849]
    • (2000) Br J Ophthalmol , vol.84 , pp. 332-336
    • Meacock, W.R.1    Spalton, D.J.2    Stanford, M.R.3
  • 17
    • 0034771382 scopus 로고    scopus 로고
    • Smad translocation and growth suppression in lens epithelial cells by endogenous TGFbeta2 during wound repair
    • [PMID: 11384156]
    • Saika S, Okada Y, Miyamoto T, Ohnishi Y, Ooshima A, McAvoy JW. Smad translocation and growth suppression in lens epithelial cells by endogenous TGFbeta2 during wound repair. Exp Eye Res 2001; 72:679-86. [PMID: 11384156]
    • (2001) Exp Eye Res , vol.72 , pp. 679-686
    • Saika, S.1    Okada, Y.2    Miyamoto, T.3    Ohnishi, Y.4    Ooshima, A.5    McAvoy, J.W.6
  • 20
    • 33747761923 scopus 로고    scopus 로고
    • On the art of identifying effective and specific siRNAs
    • [PMID: 16929310]
    • Pei Y, Tuschl T. On the art of identifying effective and specific siRNAs. Nat Methods 2006; 3:670-6. [PMID: 16929310]
    • (2006) Nat Methods , vol.3 , pp. 670-676
    • Pei, Y.1    Tuschl, T.2
  • 22
    • 0032821129 scopus 로고    scopus 로고
    • Human anti-transforming growth factor-beta2 antibody: A new glaucoma anti-scarring agent
    • [PMID: 10476787]
    • Cordeiro MF, Gay JA, Khaw PT. Human anti-transforming growth factor-beta2 antibody: a new glaucoma anti-scarring agent. Invest Ophthalmol Vis Sci 1999; 40:2225-34. [PMID: 10476787]
    • (1999) Invest Ophthalmol Vis Sci , vol.40 , pp. 2225-2234
    • Cordeiro, M.F.1    Gay, J.A.2    Khaw, P.T.3
  • 23
    • 0041342109 scopus 로고    scopus 로고
    • Evaluation of anti-TGF-beta2 antibody as a new postoperative anti-scarring agent in glaucoma surgery
    • [PMID: 12882787]
    • Mead AL, Wong TT, Cordeiro MF, Anderson IK, Khaw PT. Evaluation of anti-TGF-beta2 antibody as a new postoperative anti-scarring agent in glaucoma surgery. Invest Ophthalmol Vis Sci 2003; 44:3394-401. [PMID: 12882787]
    • (2003) Invest Ophthalmol Vis Sci , vol.44 , pp. 3394-3401
    • Mead, A.L.1    Wong, T.T.2    Cordeiro, M.F.3    Anderson, I.K.4    Khaw, P.T.5
  • 25
    • 0037123606 scopus 로고    scopus 로고
    • RNA silencing: The genome's immune system
    • [PMID: 12016302]
    • Plasterk RH. RNA silencing: the genome's immune system. Science 2002; 296:1263-5. [PMID: 12016302]
    • (2002) Science , vol.296 , pp. 1263-1265
    • Plasterk, R.H.1
  • 26
    • 0037062951 scopus 로고    scopus 로고
    • RNA interference
    • [PMID: 12110901]
    • Hannon GJ. RNA interference. Nature 2002; 418:244-51. [PMID: 12110901]
    • (2002) Nature , vol.418 , pp. 244-251
    • Hannon, G.J.1
  • 27
    • 0035942736 scopus 로고    scopus 로고
    • Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
    • [PMID: 11373684]
    • Elbashir SM, Harborth J, Lendeckel W, Yalcin A, Weber K, Tuschl T. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 2001; 411:494-8. [PMID: 11373684]
    • (2001) Nature , vol.411 , pp. 494-498
    • Elbashir, S.M.1    Harborth, J.2    Lendeckel, W.3    Yalcin, A.4    Weber, K.5    Tuschl, T.6
  • 28
    • 0031782448 scopus 로고    scopus 로고
    • Effect of cataract surgery on aqueous TGF-beta and lens epithelial cell proliferation
    • [PMID: 9660489]
    • Wallentin N, Wickstrom K, Lundberg C. Effect of cataract surgery on aqueous TGF-beta and lens epithelial cell proliferation. Invest Ophthalmol Vis Sci 1998; 39:1410-8. [PMID: 9660489]
    • (1998) Invest Ophthalmol Vis Sci , vol.39 , pp. 1410-1418
    • Wallentin, N.1    Wickstrom, K.2    Lundberg, C.3
  • 29
    • 0028278794 scopus 로고
    • Induction of cataract-like changes in rat lens epithelial explants by transforming growth factor beta
    • [PMID: 8112986]
    • Liu J, Hales AM, Chamberlain CG, McAvoy JW. Induction of cataract-like changes in rat lens epithelial explants by transforming growth factor beta. Invest Ophthalmol Vis Sci 1994; 35:388-401. [PMID: 8112986]
    • (1994) Invest Ophthalmol Vis Sci , vol.35 , pp. 388-401
    • Liu, J.1    Hales, A.M.2    Chamberlain, C.G.3    McAvoy, J.W.4
  • 31
    • 4043126747 scopus 로고    scopus 로고
    • FGF-2 counteracts loss of TGFbeta affected cells from rat lens explants: Implications for PCO (after cataract)
    • [PMID: 15303087]
    • Mansfield KJ, Cerra A, Chamberlain CG. FGF-2 counteracts loss of TGFbeta affected cells from rat lens explants: implications for PCO (after cataract). Mol Vis 2004; 10:521-32. [PMID: 15303087]
    • (2004) Mol Vis , vol.10 , pp. 521-532
    • Mansfield, K.J.1    Cerra, A.2    Chamberlain, C.G.3
  • 32
    • 22144452168 scopus 로고    scopus 로고
    • Transforming growth factor-beta-induced epithelialmesenchymal transition in the lens: A model for cataract formation
    • [PMID: 15942192]
    • de Iongh RU, Wederell E, Lovicu FJ, McAvoy JW. Transforming growth factor-beta-induced epithelialmesenchymal transition in the lens: a model for cataract formation. Cells Tissues Organs 2005; 179:43-55. [PMID: 15942192]
    • (2005) Cells Tissues Organs , vol.179 , pp. 43-55
    • de Iongh, R.U.1    Wederell, E.2    Lovicu, F.J.3    McAvoy, J.W.4
  • 33
    • 0030468424 scopus 로고    scopus 로고
    • Mitomycin against posterior capsular opacification: An experimental study in rabbits
    • [PMID: 9059276]
    • Haus CM, Galand AL. Mitomycin against posterior capsular opacification: an experimental study in rabbits. Br J Ophthalmol 1996; 80:1087-91. [PMID: 9059276]
    • (1996) Br J Ophthalmol , vol.80 , pp. 1087-1091
    • Haus, C.M.1    Galand, A.L.2
  • 34
    • 0029937953 scopus 로고    scopus 로고
    • Prevention of secondary cataract by antimitotic drugs: Experimental study
    • [PMID: 8726679]
    • Ismail MM, Alio JL, Ruiz Moreno JM. Prevention of secondary cataract by antimitotic drugs: experimental study. Ophthalmic Res 1996; 28:64-9. [PMID: 8726679]
    • (1996) Ophthalmic Res , vol.28 , pp. 64-69
    • Ismail, M.M.1    Alio, J.L.2    Ruiz Moreno, J.M.3
  • 35
    • 0027475162 scopus 로고
    • Prolonged localized tissue effects from 5-minute exposures to fluorouracil and mitomycin C
    • [PMID: 8431167]
    • Khaw PT, Doyle JW, Sherwood MB, Grierson I, Schultz G, McGorray S. Prolonged localized tissue effects from 5-minute exposures to fluorouracil and mitomycin C. Arch Ophthalmol 1993; 111:263-7. [PMID: 8431167]
    • (1993) Arch Ophthalmol , vol.111 , pp. 263-267
    • Khaw, P.T.1    Doyle, J.W.2    Sherwood, M.B.3    Grierson, I.4    Schultz, G.5    McGorray, S.6
  • 37
    • 0026475803 scopus 로고
    • Hypotonous maculopathy after trabeculectomy with subconjunctival 5-fluorouracil
    • [PMID: 1309184]
    • Stamper RL, McMenemy MG, Lieberman MF. Hypotonous maculopathy after trabeculectomy with subconjunctival 5-fluorouracil. Am J Ophthalmol 1992; 114:544-53. [PMID: 1309184]
    • (1992) Am J Ophthalmol , vol.114 , pp. 544-553
    • Stamper, R.L.1    McMenemy, M.G.2    Lieberman, M.F.3
  • 38
    • 33744757995 scopus 로고    scopus 로고
    • Role of the proteasome in TGF-beta signaling in lens epithelial cells
    • [PMID: 16639014]
    • Hosler MR, Wang-Su ST, Wagner BJ. Role of the proteasome in TGF-beta signaling in lens epithelial cells. Invest Ophthalmol Vis Sci 2006; 47:2045-52. [PMID: 16639014]
    • (2006) Invest Ophthalmol Vis Sci , vol.47 , pp. 2045-2052
    • Hosler, M.R.1    Wang-Su, S.T.2    Wagner, B.J.3
  • 39
    • 0033588964 scopus 로고    scopus 로고
    • Adenovirus-mediated suicide gene transduction: Feasibility in lens epithelium and in prevention of posterior capsule opacification in rabbits
    • [PMID: 10515456]
    • Malecaze F, Couderc B, de Neuville S, Serres B, Mallet J, Douin-Echinard V, Manenti S, Revah F, Darbon JM. Adenovirus-mediated suicide gene transduction: feasibility in lens epithelium and in prevention of posterior capsule opacification in rabbits. Hum Gene Ther 1999; 10:2365-72. [PMID: 10515456]
    • (1999) Hum Gene Ther , vol.10 , pp. 2365-2372
    • Malecaze, F.1    Couderc, B.2    de Neuville, S.3    Serres, B.4    Mallet, J.5    Douin-Echinard, V.6    Manenti, S.7    Revah, F.8    Darbon, J.M.9
  • 40
    • 0033387946 scopus 로고    scopus 로고
    • Retrovirus-mediated transfer of a suicide gene into lens epithelial cells in vitro and in an experimental model of posterior capsule opacification
    • [PMID: 10550788]
    • Couderc BC, de Neuville S, Douin-Echinard V, Serres B, Manenti S, Darbon JM, Malecaze F. Retrovirus-mediated transfer of a suicide gene into lens epithelial cells in vitro and in an experimental model of posterior capsule opacification. Curr Eye Res 1999; 19:472-82. [PMID: 10550788]
    • (1999) Curr Eye Res , vol.19 , pp. 472-482
    • Couderc, B.C.1    de Neuville, S.2    Douin-Echinard, V.3    Serres, B.4    Manenti, S.5    Darbon, J.M.6    Malecaze, F.7
  • 41
    • 3142615372 scopus 로고    scopus 로고
    • The RNAi revolution
    • [PMID: 15241403]
    • Novina CD, Sharp PA. The RNAi revolution. Nature 2004; 430:161-4. [PMID: 15241403]
    • (2004) Nature , vol.430 , pp. 161-164
    • Novina, C.D.1    Sharp, P.A.2
  • 42
    • 0038748037 scopus 로고    scopus 로고
    • Small interfering RNA (siRNA) targeting VEGF effectively inhibits ocular neovascularization in a mouse model
    • [PMID: 12789138]
    • Reich SJ, Fosnot J, Kuroki A, Tang W, Yang X, Maguire AM, Bennett J, Tolentino MJ. Small interfering RNA (siRNA) targeting VEGF effectively inhibits ocular neovascularization in a mouse model. Mol Vis 2003; 9:210-6. [PMID: 12789138]
    • (2003) Mol Vis , vol.9 , pp. 210-216
    • Reich, S.J.1    Fosnot, J.2    Kuroki, A.3    Tang, W.4    Yang, X.5    Maguire, A.M.6    Bennett, J.7    Tolentino, M.J.8
  • 43
    • 14544297836 scopus 로고    scopus 로고
    • RNA interference targeting transforming growth factor-beta type II receptor suppresses ocular inflammation and fibrosis
    • [PMID: 15475878]
    • Nakamura H, Siddiqui SS, Shen X, Malik AB, Pulido JS, Kumar NM, Yue BY. RNA interference targeting transforming growth factor-beta type II receptor suppresses ocular inflammation and fibrosis. Mol Vis 2004; 10:703-11. [PMID: 15475878]
    • (2004) Mol Vis , vol.10 , pp. 703-711
    • Nakamura, H.1    Siddiqui, S.S.2    Shen, X.3    Malik, A.B.4    Pulido, J.S.5    Kumar, N.M.6    Yue, B.Y.7
  • 44
    • 0035004208 scopus 로고    scopus 로고
    • Specific inhibition of transforming growth factor-beta2 expression in human osteoblast cells by antisense phosphorothioate oligonucleotides
    • [PMID: 11298751]
    • Shen ZJ, Kim SK, Kwon OS, Lee YS, Moon BJ. Specific inhibition of transforming growth factor-beta2 expression in human osteoblast cells by antisense phosphorothioate oligonucleotides. Eur J Biochem 2001; 268:2331-7. [PMID: 11298751]
    • (2001) Eur J Biochem , vol.268 , pp. 2331-2337
    • Shen, Z.J.1    Kim, S.K.2    Kwon, O.S.3    Lee, Y.S.4    Moon, B.J.5
  • 45
    • 0034641666 scopus 로고    scopus 로고
    • Ribozyme oligonucleotides against transforming growth factor-beta inhibited neointimal formation after vascular injury in rat model: Potential application of ribozyme strategy to treat cardiovascular disease
    • [PMID: 10982548]
    • Yamamoto K, Morishita R, Tomita N, Shimozato T, Nakagami H, Kikuchi A, Aoki M, Higaki J, Kaneda Y, Ogihara T. Ribozyme oligonucleotides against transforming growth factor-beta inhibited neointimal formation after vascular injury in rat model: potential application of ribozyme strategy to treat cardiovascular disease. Circulation 2000; 102:1308-14. [PMID: 10982548]
    • (2000) Circulation , vol.102 , pp. 1308-1314
    • Yamamoto, K.1    Morishita, R.2    Tomita, N.3    Shimozato, T.4    Nakagami, H.5    Kikuchi, A.6    Aoki, M.7    Higaki, J.8    Kaneda, Y.9    Ogihara, T.10


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