Local gene silencing of Monocyte chemoattractant protein-1 prevents vulnerable plaque disruption in apolipoprotein E-knockout mice

PLoS ONE

Volumn 7, Issue 3, 2012, Pages

  Liu, Xiao Ling ^a   Zhang, Peng Fei ^a   Ding, Shi Fang ^a   Wang, Yan ^a   Zhang, Mei ^a   Zhao, Yu Xia ^a   Ni, Mei ^a   Zhang, Yun ^a  

^a SHANDONG UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; APOLIPOPROTEIN E; COLLAGEN; ENHANCED GREEN FLUORESCENT PROTEIN; GELATINASE A; GELATINASE B; INTERLEUKIN 6; LIPID; LIPOPOLYSACCHARIDE; MACROPHAGE ELASTASE; MONOCYTE CHEMOTACTIC PROTEIN 1; SHORT HAIRPIN RNA; SODIUM CHLORIDE; TUMOR NECROSIS FACTOR ALPHA; CYTOKINE; GREEN FLUORESCENT PROTEIN; MATRIX METALLOPROTEINASE; SMALL INTERFERING RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATHEROSCLEROTIC PLAQUE; CAROTID ARTERY; CAROTID ATHEROSCLEROSIS; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; ENZYME ACTIVITY; GENE SILENCING; HISTOPATHOLOGY; KNOCKOUT MOUSE; LIPID DIET; MACROPHAGE; MALE; MOUSE; NONHUMAN; PHENOTYPE; PROTEIN EXPRESSION; PROTEIN SYNTHESIS INHIBITION; PROTEIN TARGETING; RNA INTERFERENCE; SMOOTH MUSCLE FIBER; STRESS; VIRAL GENE DELIVERY SYSTEM; VIRAL GENE THERAPY; ACUTE CORONARY SYNDROME; ANIMAL; CASE CONTROL STUDY; GENETICS; METABOLISM; MOUSE MUTANT; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ADENOVIRIDAE; MUS;

ACUTE CORONARY SYNDROME; ANIMALS; APOLIPOPROTEINS E; BLOTTING, WESTERN; CASE-CONTROL STUDIES; CHEMOKINE CCL2; CYTOKINES; GREEN FLUORESCENT PROTEINS; MALE; MATRIX METALLOPROTEINASES; MICE; MICE, KNOCKOUT; PLAQUE, ATHEROSCLEROTIC; REAL-TIME POLYMERASE CHAIN REACTION; RNA INTERFERENCE; RNA, SMALL INTERFERING;

EID: 84863297431     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0033497     Document Type: Article

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