Lycii cortex radicis extract inhibits glioma tumor growth in vitro and in vivo through downregulation of the Akt/ERK pathway

Oncology Reports

Volumn 27, Issue 5, 2012, Pages 1467-1474

  Jeong, Ji Cheon ^a   Kim, Saeng Jae ^a   Kim, Yong Keun ^b   Kwon, Chae Hwa ^b   Kim, Ki Hyung ^b,c  

^a Dongguk University   (South Korea)

^b Pusan National University School of Medicine   (South Korea)

^c Pusan National University School of Medicine   (South Korea)

Author keywords

Akt ERK; Apoptosis; Human glioma cells; Lycii cortex radicis; Reactive oxygen species; Tumor growth

Indexed keywords

ANTINEOPLASTIC AGENT; CASPASE; LYCII CORTEX RADICIS EXTRACT; MITOGEN ACTIVATED PROTEIN KINASE; PLANT EXTRACT; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER INHIBITION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; ENZYME ACTIVATION; GLIOMA; GLIOMA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LYCII CORTEX RADICIS; MALE; MEDICINAL PLANT; MOUSE; NONHUMAN; PRIORITY JOURNAL; TUMOR VOLUME; TUMOR XENOGRAFT;

ANIMALS; CELL DEATH; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GLIOMA; HUMANS; MALE; MICE; MICE, INBRED BALB C; MICE, NUDE; PLANT EXTRACTS; PROTO-ONCOGENE PROTEINS C-AKT; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84863273672     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2012.1637     Document Type: Article

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