In vitro aggregation behavior of a non-amyloidogenic λ light chain dimer deriving from U266 multiple myeloma cells

PLoS ONE

Volumn 7, Issue 3, 2012, Pages

  Arosio, Paolo ^a   Owczarz, Marta ^a   Müller Späth, Thomas ^a   Rognoni, Paola ^c   Beeg, Marten ^a   Wu, Hua ^a   Salmona, Mario ^b   Morbidelli, Massimo ^a  

^a ETH ZURICH   (Switzerland)

^b MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

^c UNIVERSITY OF PAVIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN LAMBDA CHAIN; OLIGOMER; 8 ANILINO 1 NAPHTHALENESULFONIC ACID; 8-ANILINO-1-NAPHTHALENESULFONIC ACID; AMYLOID; IMMUNOGLOBULIN LIGHT CHAIN;

ACIDITY; AMYLOIDOSIS; ARTICLE; BETA SHEET; CONTROLLED STUDY; DENATURATION; HUMAN; HUMAN CELL; MULTIPLE MYELOMA; MYELOMA CELL; PH; PROTEIN AGGREGATION; PROTEIN FUNCTION; PROTEIN SECONDARY STRUCTURE; PROTEIN STABILITY; TEMPERATURE; CHEMISTRY; CIRCULAR DICHROISM; INFRARED SPECTROSCOPY; KINETICS; LIGHT; METABOLISM; MIDDLE AGED; PROTEIN DENATURATION; PROTEIN MULTIMERIZATION; PROTEIN QUATERNARY STRUCTURE; RADIATION SCATTERING; SOLUTION AND SOLUBILITY; TUMOR CELL LINE;

MAMMALIA;

AMYLOID; ANILINO NAPHTHALENESULFONATES; CELL LINE, TUMOR; CIRCULAR DICHROISM; HUMANS; HYDROGEN-ION CONCENTRATION; IMMUNOGLOBULIN LIGHT CHAINS; KINETICS; LIGHT; MIDDLE AGED; MULTIPLE MYELOMA; PROTEIN DENATURATION; PROTEIN MULTIMERIZATION; PROTEIN STABILITY; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, SECONDARY; SCATTERING, RADIATION; SOLUTIONS; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; TEMPERATURE;

EID: 84863269470     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0033372     Document Type: Article

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