Thermodynamic instability of human λ6 light chains: Correlation with fibrillogenicity

Biochemistry

Volumn 38, Issue 42, 1999, Pages 14101-14108

  Wall, Jonathan ^a   Schell, Maria ^a   Murphy, Charles ^a   Hrncic, Rudi ^a   Stevens, Fred J ^b   Solomon, Alan ^a  

^a UNIVERSITY OF TENNESSEE GRADUATE SCHOOL OF MEDICINE   (United States)

^b ARGONNE NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGGLOMERATION; AMINO ACIDS; BIOASSAY; CELLS; CHEMICAL OPERATIONS; CLONING; DEPOSITION; DNA; MOLECULAR STRUCTURE; MOLECULES; THERMODYNAMIC STABILITY;

ALZHEIMER DISEASE; AMYLOID FIBRILS; AMYLOIDOSES; FIBRILLOGENECITY; MYELOMA; RENAL TUBULAR CASTS;

PROTEINS;

IMMUNOGLOBULIN LIGHT CHAIN;

ARTICLE; HUMAN; IMMUNOGLOBULIN STRUCTURE; MOLECULAR STABILITY; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; THERMODYNAMICS;

AMINO ACID SEQUENCE; FEMALE; HUMANS; IMMUNOGLOBULIN LAMBDA-CHAINS; IMMUNOGLOBULIN VARIABLE REGION; MALE; MICROFIBRILS; MIDDLE AGED; MOLECULAR SEQUENCE DATA; PROTEIN DENATURATION; RECOMBINANT PROTEINS; SPECTROMETRY, FLUORESCENCE; THERMODYNAMICS;

EID: 0345426278     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi991131j     Document Type: Article

References (33)

1. Falk, R. H., Comenzo, R. L., and Skinner, M. (1997) N. Engl. J. Med. 337, 898-909.
2. Westermark, P. (1997) Amyloid: Int. J. Exp. Clin. Invest. 4, 216-218.
3. Harper, J. D., and Lansbury, P. T. (1997) Annu. Rev. Biochem. 66, 385-407.
4. Isobe, T., and Osserman, E. F. (1971) N. Engl. J. Med. 290, 473-477.
5. Pascali, E. (1995) Crit. Rev. Oncol. Hematol. 19, 149-181.
6. Solomon, A., Weiss, D. T., and Kattine, A. A. (1991) N. Engl. J. Med. 324, 1845-1851.
7. Hurle, M. R., Helms, L. R., Li, L., Chan, W., and Wetzel, R. (1994) Proc. Natl. Acad. Sci. U.S.A. 91, 5446-5450.
8. Bellotti, V., Stoppini, M., Mangione, P. P., Fornasieri, A., Min, L., Merlini, G., and Fern, G. (1996) Biochim. Biophys. Acta 1317, 161-167.
9. Stevens, P. W., Raffen, R., Hanson, D. K., Deng, Y.-L., Berrios-Hammond, M., Westholm, F. A., Murphy, C., Eulitz, M., Wetzel, R., Schiffer, M., and Stevens, F. J. (1995) Protein Sci. 4, 421-432.
10. Abe, M., Ozaki, S., Wolfenbarger, D., deBram-Hart, M., Weiss, D. T., and Solomon, A. (1994) J. Clin. Lab. Anal. 8, 4-9.
11. Chirgin, J. M., Przybyla, A. E., MacDonald, R. J., and Rutter, W. J. (1979) Biochemistry 18, 5294-5299.
12. Ch'ang, L.-Y., Yen, C.-P., Besl, L., Schell, M., and Solomon, A. (1994) Mol. Immunol. 31, 531-536.
13. Sanger, F., Nicklen, S., and Coulson, A. R. (1977) Proc. Natl. Acad. Sci. U.S.A. 74, 5463-5467.
14. Sambrook, J., Fritsch, E. F., and Maniatis, T. (1989) Molecular Cloning: A Laboratory Manual, 2nd ed., Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
15. Santoro, M. M., and Bolen, D. W. (1988) Biochemistry 27, 8063-8068.
16. Pace, C. N., Shirley, B. A., and Thomson, J. A. (1989) in Protein Structure: a Practical Approach (Creighton, T. E., Ed.) pp 311-330, IRL Press, Oxford.
17. Eftink, M. R. (1995) Methods Enzymol. 259, 487-512.
18. Milardi, D., la Rosa, C., Fasone, S., and Grasso, D. (1997) Biophys. Chem. 69, 43-51.
19. Bishop, M. F., and Ferrone, F. A. (1984) Biophys. J. 46, 631-644.
20. Pokkuluri, P. R., Solomon, A., Weiss, D. T., Stevens, F. J., and Schiffer, M. (1999) Amyloid: Int. J. Exp. Clin. Invest. (submitted for publication).
21. Naiki, H., Higuchi, K., Hosokawa, M., and Takeda, T. (1989) Anal. Biochem. 177, 244-249.
22. Hurle, M. R., Helms, L. R., Li, L., Chan, W., and Wetzel, R. (1994) Proc. Natl. Acad. Sci. U.S.A. 91, 5446-5450.
23. Chan, W., Helms, L. R., Brooks, I., Lee, G., Ngola, S., McNulty, D., Maleeff, B., Hensley, P., and Wetzel, R. (1996) Folding Des. 1, 77-89.
24. Helms, L. R., and Wetzel, R. (1996) J. Mol. Biol. 257, 77-86.
25. Kelly, J. W. (1996) Curr. Opin. Struct. Biol. 6, 11-7.
26. Solomon, A., Frangione, B., and Franklin, E. C. (1982) J. Clin. Invest. 70, 453-460.
27. Ghiso, J., Solomon, A., and Frangione, B. (1986) J. Immunol. 136, 716-719.
28. Wetzel, R. (1997) Adv. Protein Chem. 50, 183-242.
29. Helms, L. R., and Wetzel, R. (1995) Protein Sci. 4, 2073-2081.
30. Zav'yalov, V. P., Troitsky, G. V., Khechinashvili, N. N., and Privalov, P. L. (1977) Biochim. Biophys. Acta 492, 102-111.
31. Piekarska, B., Skowronek, M., Rybarska, J., Stopa, B., Roterman, I., and Konieczny, L. (1996) Biochimie 78, 183-189.
32. Solomon, A., Waldmann, T. A., Fahey, J. L., and McFarlane, A. S. (1964) J. Clin. Invest. 43, 103-117.
33. Kabat, E. A., Wu, T. T., Perry, H. M., Gottesman, K. S., and Foeller, C. (1991) Sequences of proteins of Immunological Interest, Vol. 5th, National Institutes of Health, Bethesda, MD.