A novel naturally occurring salicylic acid analogue acts as an anti-inflammatory agent by inhibiting nuclear factor-kappaB activity in RAW264.7 macrophages

Molecular Pharmaceutics

Volumn 9, Issue 3, 2012, Pages 671-677

  Zhang, Tiantai ^a   Sun, Lan ^a   Liu, Rui ^a   Zhang, Dan ^a   Lan, Xi ^a   Huang, Chao ^a   Xin, Wenyu ^a   Wang, Chao ^a   Zhang, Dongming ^a   Du, Guanhua ^a  

^a INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

anti inflammation; Gaultheria yunnanensis; methyl salicylate 2 O D lactoside, TNF ; NF B signaling pathway

Indexed keywords

CYTOKINE; DL 0309; I KAPPA B ALPHA; I KAPPA B KINASE BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; METHYLSALICYLATE 2 O BETA LACTOSIDE; NITRIC OXIDE; REACTIVE OXYGEN METABOLITE; SALICYLIC ACID DERIVATIVE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG MECHANISM; GAULTHERIA; GAULTHERIA YUNNANENSIS; GEL MOBILITY SHIFT ASSAY; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; WESTERN BLOTTING;

ANIMALS; ANTI-INFLAMMATORY AGENTS; BLOTTING, WESTERN; CELL LINE; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ENZYME-LINKED IMMUNOSORBENT ASSAY; GAULTHERIA; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; NF-KAPPA B; REACTIVE OXYGEN SPECIES; SALICYLIC ACID; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84863262982     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp2003779     Document Type: Article

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