PI3K/Akt contributes to increased expression of Toll-like receptor 4 in macrophages exposed to hypoxic stress

Biochemical and Biophysical Research Communications

Volumn 419, Issue 3, 2012, Pages 466-471

  Kim, So Young ^a   Jeong, Eunshil ^a   Joung, Sun Myung ^a   Lee, Joo Young ^a,b  

^a Gwangju Institute of Science and Technology (GIST)   (South Korea)

^b The Catholic University of Korea   (South Korea)

Author keywords

Akt; HIF 1; Hypoxic stress; PI3K; Toll like receptor

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; HYPOXIA INDUCIBLE FACTOR 1; MESSENGER RNA; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SMALL INTERFERING RNA; SULFORAPHANE; TOLL LIKE RECEPTOR 4;

ANIMAL CELL; ARTICLE; CELL HYPOXIA; CELL NUCLEUS; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; GENE SILENCING; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

ANIMALS; CELL HYPOXIA; CELL LINE; CHROMONES; COBALT; GENE KNOCKDOWN TECHNIQUES; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MACROPHAGES; MICE; MORPHOLINES; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RNA, MESSENGER; STRESS, PHYSIOLOGICAL; THIOCYANATES; TOLL-LIKE RECEPTOR 4; TRANSCRIPTION, GENETIC; UP-REGULATION;

EID: 84863254048     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2012.02.015     Document Type: Article

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