Inhibition of fetal bone development through epigenetic down-regulation of HoxA10 in obese rats fed high-fat diet

FASEB Journal

Volumn 26, Issue 3, 2012, Pages 1131-1141

  Chen, Jin Ran ^a,b   Zhang, Jian ^a,b   Lazarenko, Oxana P ^a,b   Kang, Ping ^a   Blackburn, Michael L ^a,b   Ronis, Martin J J ^a,b   Badger, Thomas M ^a,b   Shankar, Kartik ^a,b  

^a U S DEPARTMENT OF AGRICULTURE   (United States)

^b UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

Free fatty acid; Methylation; Osteoblast; Osteogenesis

Indexed keywords

FATTY ACID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; TRANSCRIPTION FACTOR HOXA10;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE DEVELOPMENT; CONTROLLED STUDY; DNA METHYLATION; DOWN REGULATION; EPIGENETICS; FEMALE; FETUS; FETUS DEVELOPMENT; LIPID DIET; MATERNAL DISEASE; NONHUMAN; NUCLEOTIDE SEQUENCE; OBESITY; OSTEOBLAST; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; RAT;

ANIMALS; BLOTTING, WESTERN; BONE DEVELOPMENT; CELL LINE; CELLS, CULTURED; DIETARY FATS; DNA METHYLATION; DOWN-REGULATION; EMBRYO, MAMMALIAN; EPIGENESIS, GENETIC; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HOMEODOMAIN PROTEINS; MALE; OBESITY; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PREGNANCY; PREGNANCY COMPLICATIONS; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SKULL; TIME FACTORS;

RATTUS;

EID: 84863251576     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.11-197822     Document Type: Article

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