A role for ethanol-induced oxidative stress in controlling lineage commitment of mesenchymal stromal cells through inhibition of Wnt/β-catenin signaling

Journal of Bone and Mineral Research

Volumn 25, Issue 5, 2010, Pages 1117-1127

  Chen, Jin Ran ^a,b   Lazarenko, Oxana P ^a,b   Shankar, Kartik ^a,b   Blackburn, Michael L ^a,b   Badger, Thomas M ^a,b   Ronis, Martin J ^a,b  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^b U S DEPARTMENT OF AGRICULTURE   (United States)

Author keywords

catenin; Ethanol; N acetylcysteine; Osteoblast; WNT

Indexed keywords

ACETYLCYSTEINE; ALCOHOL; ALKALINE PHOSPHATASE; BETA CATENIN; BIOLOGICAL MARKER; GLYCOGEN SYNTHASE KINASE 3BETA; OSTEOCALCIN; WNT PROTEIN;

ADIPOGENESIS; ALCOHOL CONSUMPTION; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BONE DENSITY; BONE TISSUE; CELL LINEAGE; COMPETITIVE INHIBITION; CONTROLLED STUDY; DEPHOSPHORYLATION; DOWN REGULATION; FEMALE; GENE EXPRESSION; GENETIC TRANSCRIPTION; LACTATION; MALE; MESENCHYMAL STEM CELL; NONHUMAN; OSSIFICATION; OSTEOBLAST; OSTEOLYSIS; OXIDATIVE STRESS; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; RNA ISOLATION; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT; STROMA CELL; UPREGULATION; WEANING;

ACETYLCYSTEINE; ADIPOGENESIS; ANIMALS; BETA CATENIN; BONE DENSITY; CELL DIFFERENTIATION; CELL LINEAGE; DOWN-REGULATION; ETHANOL; FEMALE; GLYCOGEN SYNTHASE KINASE 3; LACTATION; MESENCHYMAL STEM CELLS; OSTEOGENESIS; OXIDATIVE STRESS; PREGNANCY; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; TCF TRANSCRIPTION FACTORS; WNT PROTEINS;

EID: 77953483918     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1002/jbmr.7     Document Type: Article

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