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Volumn 36, Issue 1, 2012, Pages 2006-2016

Doxycycline treatment in a neonatal rat model of hypoxia-ischemia reduces cerebral tissue and white matter injury: A longitudinal magnetic resonance imaging study

Author keywords

Brain injury; Diffusion tensor imaging; Inflammation; Manganese enhanced magnetic resonance imaging; Microglia

Indexed keywords

DOXYCYCLINE; DOXYFERM; UNCLASSIFIED DRUG;

EID: 84863217835     PISSN: 0953816X     EISSN: 14609568     Source Type: Journal    
DOI: 10.1111/j.1460-9568.2012.08114.x     Document Type: Article
Times cited : (19)

References (37)
  • 1
    • 0036289498 scopus 로고    scopus 로고
    • Minocycline markedly protects the neonatal brain against hypoxic-ischemic injury
    • Arvin, K.L., Han, B.H., Du, Y., Lin, S.Z., Paul, S.M. & Holtzman, D.M. (2002) Minocycline markedly protects the neonatal brain against hypoxic-ischemic injury. Ann. Neurol., 52, 54-61.
    • (2002) Ann. Neurol , vol.52 , pp. 54-61
    • Arvin, K.L.1    Han, B.H.2    Du, Y.3    Lin, S.Z.4    Paul, S.M.5    Holtzman, D.M.6
  • 4
    • 62849106987 scopus 로고    scopus 로고
    • Minocycline: a neuroprotective agent for hypoxic-ischemic brain injury in the neonate?
    • Buller, K.M., Carty, M.L., Reinebrant, H.E. & Wixey, J.A. (2009) Minocycline: a neuroprotective agent for hypoxic-ischemic brain injury in the neonate? J. Neurosci. Res., 87, 599-608.
    • (2009) J. Neurosci. Res. , vol.87 , pp. 599-608
    • Buller, K.M.1    Carty, M.L.2    Reinebrant, H.E.3    Wixey, J.A.4
  • 5
    • 29744434032 scopus 로고    scopus 로고
    • Minocycline alleviates hypoxic-ischemic injury to developing oligodendrocytes in the neonatal rat brain
    • Cai, Z., Lin, S., Fan, L.W., Pang, Y. & Rhodes, P.G. (2006) Minocycline alleviates hypoxic-ischemic injury to developing oligodendrocytes in the neonatal rat brain. Neuroscience, 137, 425-435.
    • (2006) Neuroscience , vol.137 , pp. 425-435
    • Cai, Z.1    Lin, S.2    Fan, L.W.3    Pang, Y.4    Rhodes, P.G.5
  • 6
    • 43049181767 scopus 로고    scopus 로고
    • Post-insult minocycline treatment attenuates hypoxia-ischemia-induced neuroinflammation and white matter injury in the neonatal rat: a comparison of two different dose regimens
    • Carty, M.L., Wixey, J.A., Colditz, P.B. & Buller, K.M. (2008) Post-insult minocycline treatment attenuates hypoxia-ischemia-induced neuroinflammation and white matter injury in the neonatal rat: a comparison of two different dose regimens. Int. J. Dev. Neurosci., 26, 477-485.
    • (2008) Int. J. Dev. Neurosci. , vol.26 , pp. 477-485
    • Carty, M.L.1    Wixey, J.A.2    Colditz, P.B.3    Buller, K.M.4
  • 7
    • 0028278413 scopus 로고
    • Reduction of central nervous system reperfusion injury in rabbits using doxycycline treatment
    • discussion 1416
    • Clark, W.M., Calcagno, F.A., Gabler, W.L., Smith, J.R. & Coull, B.M. (1994) Reduction of central nervous system reperfusion injury in rabbits using doxycycline treatment, Stroke, 25, 1411-1415; discussion 1416.
    • (1994) Stroke , vol.25 , pp. 1411-1415
    • Clark, W.M.1    Calcagno, F.A.2    Gabler, W.L.3    Smith, J.R.4    Coull, B.M.5
  • 8
    • 33746254939 scopus 로고    scopus 로고
    • Minocycline attenuates hypoxia-ischemia-induced neurological dysfunction and brain injury in the juvenile rat
    • Fan, L.W., Lin, S., Pang, Y., Rhodes, P.G. & Cai, Z. (2006) Minocycline attenuates hypoxia-ischemia-induced neurological dysfunction and brain injury in the juvenile rat. Eur. J. Neurosci., 24, 341-350.
    • (2006) Eur. J. Neurosci. , vol.24 , pp. 341-350
    • Fan, L.W.1    Lin, S.2    Pang, Y.3    Rhodes, P.G.4    Cai, Z.5
  • 9
    • 7444267966 scopus 로고    scopus 로고
    • Neonatal brain injury
    • Ferriero, D.M. (2004) Neonatal brain injury. N. Engl. J. Med., 351, 1985-1995.
    • (2004) N. Engl. J. Med. , vol.351 , pp. 1985-1995
    • Ferriero, D.M.1
  • 11
    • 0035340273 scopus 로고    scopus 로고
    • Acute and chronic changes of the apparent diffusion coefficient in neurological disorders - biophysical mechanisms and possible underlying histopathology
    • Gass, A., Niendorf, T. & Hirsch, J.G. (2001) Acute and chronic changes of the apparent diffusion coefficient in neurological disorders - biophysical mechanisms and possible underlying histopathology. J. Neurol. Sci., 186(Suppl 1), S15-23.
    • (2001) J. Neurol. Sci. , vol.186 , Issue.SUPPL. 1
    • Gass, A.1    Niendorf, T.2    Hirsch, J.G.3
  • 12
    • 0035743242 scopus 로고    scopus 로고
    • Delayed cerebral atrophy following moderate hypoxia-ischemia in the immature rat
    • Geddes, R., Vannucci, R.C. & Vannucci, S.J. (2001) Delayed cerebral atrophy following moderate hypoxia-ischemia in the immature rat. Dev. Neurosci., 23, 180-185.
    • (2001) Dev. Neurosci. , vol.23 , pp. 180-185
    • Geddes, R.1    Vannucci, R.C.2    Vannucci, S.J.3
  • 13
    • 70450200545 scopus 로고    scopus 로고
    • Neuroprotection in the newborn infant
    • Gonzalez, F.F. & Ferriero, D.M. (2009) Neuroprotection in the newborn infant. Clin. Perinatol., 36, 859-880.
    • (2009) Clin. Perinatol. , vol.36 , pp. 859-880
    • Gonzalez, F.F.1    Ferriero, D.M.2
  • 14
    • 75449108143 scopus 로고    scopus 로고
    • Doxycycline inhibits proinflammatory cytokines but not acute cerebral cytogenesis after hypoxia-ischemia in neonatal rats
    • Jantzie, L.L. & Todd, K.G. (2010) Doxycycline inhibits proinflammatory cytokines but not acute cerebral cytogenesis after hypoxia-ischemia in neonatal rats. J. Psychiatry Neurosci., 35, 20-32.
    • (2010) J. Psychiatry Neurosci. , vol.35 , pp. 20-32
    • Jantzie, L.L.1    Todd, K.G.2
  • 15
    • 14644437067 scopus 로고    scopus 로고
    • Doxycycline reduces cleaved caspase-3 and microglial activation in an animal model of neonatal hypoxia-ischemia
    • Jantzie, L.L., Cheung, P.Y. & Todd, K.G. (2005) Doxycycline reduces cleaved caspase-3 and microglial activation in an animal model of neonatal hypoxia-ischemia. J. Cereb. Blood Flow Metab., 25, 314-324.
    • (2005) J. Cereb. Blood Flow Metab. , vol.25 , pp. 314-324
    • Jantzie, L.L.1    Cheung, P.Y.2    Todd, K.G.3
  • 16
    • 33751050878 scopus 로고    scopus 로고
    • The effects of doxycycline administration on amino acid neurotransmitters in an animal model of neonatal hypoxia-ischemia
    • Jantzie, L.L., Rauw, G.A. & Todd, K.G. (2006) The effects of doxycycline administration on amino acid neurotransmitters in an animal model of neonatal hypoxia-ischemia. Neurochem. Int., 49, 717-728.
    • (2006) Neurochem. Int. , vol.49 , pp. 717-728
    • Jantzie, L.L.1    Rauw, G.A.2    Todd, K.G.3
  • 17
    • 41449091346 scopus 로고    scopus 로고
    • Pathogenesis of cerebral white matter injury of prematurity
    • Khwaja, O. & Volpe, J.J. (2008) Pathogenesis of cerebral white matter injury of prematurity. Arch. Dis. Child. Fetal Neonatal Ed., 93, F153-161.
    • (2008) Arch. Dis. Child. Fetal Neonatal Ed. , vol.93
    • Khwaja, O.1    Volpe, J.J.2
  • 18
    • 34547640300 scopus 로고    scopus 로고
    • Minocycline modulates chemokine receptors but not interleukin-10 mRNA expression in hypoxic-ischemic neonatal rat brain
    • Kremlev, S.G., Roberts, R.L. & Palmer, C. (2007) Minocycline modulates chemokine receptors but not interleukin-10 mRNA expression in hypoxic-ischemic neonatal rat brain. J. Neurosci. Res., 85, 2450-2459.
    • (2007) J. Neurosci. Res. , vol.85 , pp. 2450-2459
    • Kremlev, S.G.1    Roberts, R.L.2    Palmer, C.3
  • 19
    • 79961072233 scopus 로고    scopus 로고
    • Diffusion characteristics associated with neuronal injury and glial activation following hypoxia-ischemia in the immature brain
    • Lodygensky, G.A., West, T., Moravec, M.D., Back, S.A., Dikranian, K., Holtzman, D.M. & Neil, J.J. (2011) Diffusion characteristics associated with neuronal injury and glial activation following hypoxia-ischemia in the immature brain. Magn. Reson. Med., 66, 839-845.
    • (2011) Magn. Reson. Med. , vol.66 , pp. 839-845
    • Lodygensky, G.A.1    West, T.2    Moravec, M.D.3    Back, S.A.4    Dikranian, K.5    Holtzman, D.M.6    Neil, J.J.7
  • 20
    • 0028854649 scopus 로고
    • Microglia activation after neonatal hypoxic-ischemia
    • Mcrae, A., Gilland, E., Bona, E. & Hagberg, H. (1995) Microglia activation after neonatal hypoxic-ischemia. Dev. Brain Res., 84, 245-252.
    • (1995) Dev. Brain Res. , vol.84 , pp. 245-252
    • Mcrae, A.1    Gilland, E.2    Bona, E.3    Hagberg, H.4
  • 21
    • 33748047806 scopus 로고    scopus 로고
    • Principles of diffusion tensor imaging and its applications to basic neuroscience research
    • Mori, S. & Zhang, J. (2006) Principles of diffusion tensor imaging and its applications to basic neuroscience research. Neuron, 51, 527-539.
    • (2006) Neuron , vol.51 , pp. 527-539
    • Mori, S.1    Zhang, J.2
  • 22
    • 0035052738 scopus 로고    scopus 로고
    • Relation of apparent diffusion coefficient changes and metabolic disturbances after 1hour of focal cerebral ischemia and at different reperfusion phases in rats
    • Olah, L., Wecker, S. & Hoehn, M. (2001) Relation of apparent diffusion coefficient changes and metabolic disturbances after 1hour of focal cerebral ischemia and at different reperfusion phases in rats. J. Cereb. Blood Flow Metab., 21, 430-439.
    • (2001) J. Cereb. Blood Flow Metab. , vol.21 , pp. 430-439
    • Olah, L.1    Wecker, S.2    Hoehn, M.3
  • 24
    • 0019366919 scopus 로고
    • The influence of immaturity on hypoxic-ischemic brain damage in the rat
    • Rice, J.E., 3rd, Vannucci, R.C. & Brierley, J.B. (1981) The influence of immaturity on hypoxic-ischemic brain damage in the rat. Neurol, Ann, 9, 131-141.
    • (1981) Neurol, Ann , vol.9 , pp. 131-141
    • Rice 3rd, J.E.1    Vannucci, R.C.2    Brierley, J.B.3
  • 26
    • 0036430645 scopus 로고    scopus 로고
    • Dysmyelination revealed through MRI as increased radial (but unchanged axial) diffusion of water
    • Song, S.K., Sun, S.W., Ramsbottom, M.J., Chang, C., Russell, J. & Cross, A.H. (2002) Dysmyelination revealed through MRI as increased radial (but unchanged axial) diffusion of water. Neuroimage, 17, 1429-1436.
    • (2002) Neuroimage , vol.17 , pp. 1429-1436
    • Song, S.K.1    Sun, S.W.2    Ramsbottom, M.J.3    Chang, C.4    Russell, J.5    Cross, A.H.6
  • 28
    • 4644236077 scopus 로고    scopus 로고
    • Hypoxia-ischemia in the immature brain
    • Vannucci, S.J. & Hagberg, H. (2004) Hypoxia-ischemia in the immature brain. J. Exp. Biol., 207, 3149-3154.
    • (2004) J. Exp. Biol. , vol.207 , pp. 3149-3154
    • Vannucci, S.J.1    Hagberg, H.2
  • 29
    • 23244434256 scopus 로고    scopus 로고
    • Perinatal hypoxic-ischemic brain damage: evolution of an animal model
    • Vannucci, R.C. & Vannucci, S.J. (2005) Perinatal hypoxic-ischemic brain damage: evolution of an animal model. Dev. Neurosci., 27, 81-86.
    • (2005) Dev. Neurosci. , vol.27 , pp. 81-86
    • Vannucci, R.C.1    Vannucci, S.J.2
  • 30
    • 57149118216 scopus 로고    scopus 로고
    • Brain injury in premature infants: a complex amalgam of destructive and developmental disturbances
    • Volpe, J.J. (2009) Brain injury in premature infants: a complex amalgam of destructive and developmental disturbances. Lancet Neurol, 8, 110-124.
    • (2009) Lancet Neurol , vol.8 , pp. 110-124
    • Volpe, J.J.1
  • 31
    • 33644868837 scopus 로고    scopus 로고
    • Hypoxic-ischemic brain injury in the neonatal rat model: relationship between lesion size at early MR imaging and irreversible infarction
    • Wang, Y., Cheung, P.T., Shen, G.X., Wu, E.X., Cao, G., Bart, I., Wong, W.H. & Khong, P.L. (2006) Hypoxic-ischemic brain injury in the neonatal rat model: relationship between lesion size at early MR imaging and irreversible infarction. AJNR Am. J. Neuroradiol., 27, 51-54.
    • (2006) AJNR Am. J. Neuroradiol. , vol.27 , pp. 51-54
    • Wang, Y.1    Cheung, P.T.2    Shen, G.X.3    Wu, E.X.4    Cao, G.5    Bart, I.6    Wong, W.H.7    Khong, P.L.8
  • 32
    • 46249093716 scopus 로고    scopus 로고
    • Early diffusion-weighted MRI as a predictor of caspase-3 activation after hypoxic-ischemic insult in neonatal rodents
    • Wendland, M.F., Faustino, J., West, T., Manabat, C., Holtzman, D.M. & Vexler, Z.S. (2008) Early diffusion-weighted MRI as a predictor of caspase-3 activation after hypoxic-ischemic insult in neonatal rodents. Stroke, 39, 1862-1868.
    • (2008) Stroke , vol.39 , pp. 1862-1868
    • Wendland, M.F.1    Faustino, J.2    West, T.3    Manabat, C.4    Holtzman, D.M.5    Vexler, Z.S.6
  • 34
    • 79960695147 scopus 로고    scopus 로고
    • Longitudinal manganese-enhanced magnetic resonance imaging of delayed brain damage after hypoxic-ischemic injury in the neonatal rat
    • Wideroe, M., Brekken, C., Kavelaars, A., Pedersen, T.B., Goa, P.E., Heijnen, C., Skranes, J. & Brubakk, A.M. (2011) Longitudinal manganese-enhanced magnetic resonance imaging of delayed brain damage after hypoxic-ischemic injury in the neonatal rat. Neonatology, 100, 363-372.
    • (2011) Neonatology , vol.100 , pp. 363-372
    • Wideroe, M.1    Brekken, C.2    Kavelaars, A.3    Pedersen, T.B.4    Goa, P.E.5    Heijnen, C.6    Skranes, J.7    Brubakk, A.M.8
  • 35
    • 79955473599 scopus 로고    scopus 로고
    • Efficacy of post-insult minocycline administration to alter long-term hypoxia-ischemia-induced damage to the serotonergic system in the immature rat brain
    • Wixey, J.A., Reinebrant, H.E., Spencer, S.J. & Buller, K.M. (2011) Efficacy of post-insult minocycline administration to alter long-term hypoxia-ischemia-induced damage to the serotonergic system in the immature rat brain. Neuroscience, 182, 184-192.
    • (2011) Neuroscience , vol.182 , pp. 184-192
    • Wixey, J.A.1    Reinebrant, H.E.2    Spencer, S.J.3    Buller, K.M.4
  • 37
    • 0034745001 scopus 로고    scopus 로고
    • Segmentation of brain MR images through a hidden Markov random field model and the expectation-maximization algorithm
    • Zhang, Y., Brady, M. & Smith, S. (2001) Segmentation of brain MR images through a hidden Markov random field model and the expectation-maximization algorithm. IEEE Trans. Med. Imaging, 20, 45-57.
    • (2001) IEEE Trans. Med. Imaging , vol.20 , pp. 45-57
    • Zhang, Y.1    Brady, M.2    Smith, S.3


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