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Volumn 125, Issue 9, 2012, Pages 1586-1593

Role of baicalin in regulating Toll-like receptor 2/4 after ischemic neuronal injury

Author keywords

Baicalin; Cerebral ischemia reperfusion; Neuron; Oxygen glucose deprivation; Toll like receptor 2 4

Indexed keywords

BAICALIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; MYELOID DIFFERENTIATION FACTOR 88; SMALL INTERFERING RNA; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA;

EID: 84863200124     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: 10.3760/cma.j.issn.0366-6999.2012.09.012     Document Type: Article
Times cited : (44)

References (33)
  • 3
    • 59349107204 scopus 로고    scopus 로고
    • NF-kappa B singnaling in cerebral ischemia
    • Ridder DA, Schwaninger M. NF-kappa B singnaling in cerebral ischemia. J Neurosci 2009; 156: 995-1006.
    • (2009) J Neurosci , vol.156 , pp. 995-1006
    • Ridder, D.A.1    Schwaninger, M.2
  • 4
    • 4143132253 scopus 로고    scopus 로고
    • Trypanosoma cruzi and its components as exogenous mediators of inflammation recognized through Toll-like receptors
    • Campos MA, Gazzinelli RT. Trypanosoma cruzi and its components as exogenous mediators of inflammation recognized through Toll-like receptors. Mediators Inflamm 2004; 13: 139-143.
    • (2004) Mediators Inflamm , vol.13 , pp. 139-143
    • Campos, M.A.1    Gazzinelli, R.T.2
  • 5
    • 0035524488 scopus 로고    scopus 로고
    • Toll-like receptors and innate immunity
    • Medhzitov R. Toll-like receptors and innate immunity. Nat Rev Immunol 2001; 1: 135-145.
    • (2001) Nat Rev Immunol , vol.1 , pp. 135-145
    • Medhzitov, R.1
  • 6
    • 59349112140 scopus 로고    scopus 로고
    • Microglial clearance function in health and disease
    • Napoli I, Neumann H. Microglial clearance function in health and disease. J Neurosci 2009; 158: 1030-1038.
    • (2009) J Neurosci , vol.158 , pp. 1030-1038
    • Napoli, I.1    Neumann, H.2
  • 7
    • 71549121038 scopus 로고    scopus 로고
    • A novel anti-neuroinflammatory pyridylimidazole compound KR-31360
    • Ock J, Kim S, Yi KY, Kim NJ, Han HS, Cho JY, et al. A novel anti-neuroinflammatory pyridylimidazole compound KR-31360. Biochem Pharmacol 2010; 79: 596-609.
    • (2010) Biochem Pharmacol , vol.79 , pp. 596-609
    • Ock, J.1    Kim, S.2    Yi, K.Y.3    Kim, N.J.4    Han, H.S.5    Cho, J.Y.6
  • 8
    • 59349100950 scopus 로고    scopus 로고
    • System infection and inflammation in acute CNS injury and chronic neurodegeneration: Underlying mechanisms
    • Teeling JL, Perry VH. System infection and inflammation in acute CNS injury and chronic neurodegeneration: underlying mechanisms. J Neurosci 2009; 158: 1062-1073.
    • (2009) J Neurosci , vol.158 , pp. 1062-1073
    • Teeling, J.L.1    Perry, V.H.2
  • 9
    • 49349097868 scopus 로고    scopus 로고
    • Toll-like receptor-4 mediates neuronal apoptosis induced by amyloid β-peptide and the membrane lipid peroxidation product 4-hydroxynonenal
    • Tang SC, Lathia JD, Selvaraj PK, Jo DG, Mughal MR, Cheng AW, et al, Toll-like receptor-4 mediates neuronal apoptosis induced by amyloid β-peptide and the membrane lipid peroxidation product 4-hydroxynonenal. Exp Neurol 2008; 213: 114-121.
    • (2008) Exp Neurol , vol.213 , pp. 114-121
    • Tang, S.C.1    Lathia, J.D.2    Selvaraj, P.K.3    Jo, D.G.4    Mughal, M.R.5    Cheng, A.W.6
  • 10
    • 78049302588 scopus 로고    scopus 로고
    • Comprehensive study of baicalin down-regulating NOD2 receptor expression of neurons with oxygen-glucose deprivation in vitro and cerebral ischemia-reperfusion in vivo
    • Li HY, Hu J, Ma L, Yuan ZY, Wang YG, Wang XK, et al. Comprehensive study of baicalin down-regulating NOD2 receptor expression of neurons with oxygen-glucose deprivation in vitro and cerebral ischemia-reperfusion in vivo. Eur J Pharmacol 2010; 649: 92-99.
    • (2010) Eur J Pharmacol , vol.649 , pp. 92-99
    • Li, H.Y.1    Hu, J.2    Ma, L.3    Yuan, Z.Y.4    Wang, Y.G.5    Wang, X.K.6
  • 11
    • 33846938772 scopus 로고    scopus 로고
    • The flavonoid baicalin protects against cerebrovascular dysfunction and brain inflammation in experimental heatstroke
    • Chang CP, Huang WT, Cheng BC, Hsu CC, Lin MT. The flavonoid baicalin protects against cerebrovascular dysfunction and brain inflammation in experimental heatstroke. Neuropharmacology 2007; 52: 1024-1033.
    • (2007) Neuropharmacology , vol.52 , pp. 1024-1033
    • Chang, C.P.1    Huang, W.T.2    Cheng, B.C.3    Hsu, C.C.4    Lin, M.T.5
  • 12
    • 33751292170 scopus 로고    scopus 로고
    • A comparative study on the individual and combined effects of baicalin and jasminoidin on focal cerebral ischemiareperfusion injury
    • Zhang ZJ, Li P, Wang Z, Li PT, Zhang WS, Sun ZH, et al. A comparative study on the individual and combined effects of baicalin and jasminoidin on focal cerebral ischemiareperfusion injury. Brain Res 2006; 1123: 188-195.
    • (2006) Brain Res , vol.1123 , pp. 188-195
    • Zhang, Z.J.1    Li, P.2    Wang, Z.3    Li, P.T.4    Zhang, W.S.5    Sun, Z.H.6
  • 13
    • 33749235315 scopus 로고    scopus 로고
    • Baicalein inhibition of oxidative-stress-induced apoptosis via modulation of ERKs activation and induction of HO-1 gene expression in rat glioma cells C6
    • Chen YC, Chow JM, Lin CW, Wu CY, Shen SC. Baicalein inhibition of oxidative-stress-induced apoptosis via modulation of ERKs activation and induction of HO-1 gene expression in rat glioma cells C6. Toxicol Appl Pharmcol 2006; 216: 263-273.
    • (2006) Toxicol Appl Pharmcol , vol.216 , pp. 263-273
    • Chen, Y.C.1    Chow, J.M.2    Lin, C.W.3    Wu, C.Y.4    Shen, S.C.5
  • 14
    • 0142122137 scopus 로고    scopus 로고
    • Differential effects of natural polyphenols on neuronal survival in primary cultured central neurons against glutamate-and glucose deprivation-induced neuronal death
    • Lee HH, Yang LL, Wang CC, Hu SY, Chang SF, Lee YH. Differential effects of natural polyphenols on neuronal survival in primary cultured central neurons against glutamate-and glucose deprivation-induced neuronal death. Brain Res 2003; 986: 103-113.
    • (2003) Brain Res , vol.986 , pp. 103-113
    • Lee, H.H.1    Yang, L.L.2    Wang, C.C.3    Hu, S.Y.4    Chang, S.F.5    Lee, Y.H.6
  • 15
    • 0033829034 scopus 로고    scopus 로고
    • The flavonoid baicalin exhibits anti-inflammatory activity by binding to chemokines
    • Li BQ, Fu T, Gong WH, Dunlop N, Kung HF, Yan YD, et al. The flavonoid baicalin exhibits anti-inflammatory activity by binding to chemokines. Immunopharmacology 2000; 49: 295-306.
    • (2000) Immunopharmacology , vol.49 , pp. 295-306
    • Li, B.Q.1    Fu, T.2    Gong, W.H.3    Dunlop, N.4    Kung, H.F.5    Yan, Y.D.6
  • 16
    • 61849088960 scopus 로고    scopus 로고
    • Differential roles of TLR2 and TLR4 in acute focal cerebral ischemia/reperfusion injury in mice
    • Hua F, Ma J, Ha TZ, Kelley JL, Kao RL, Schweitzer JB, et al. Differential roles of TLR2 and TLR4 in acute focal cerebral ischemia/reperfusion injury in mice. Brain Res 2009; 1262: 100-108.
    • (2009) Brain Res , vol.1262 , pp. 100-108
    • Hua, F.1    Ma, J.2    Ha, T.Z.3    Kelley, J.L.4    Kao, R.L.5    Schweitzer, J.B.6
  • 17
    • 78049266766 scopus 로고    scopus 로고
    • The roles of TNF in brain dysfunction and disease
    • Clark IA, Alleva LM, Vissel B. The roles of TNF in brain dysfunction and disease. Pharmacol Ther 2010; 128: 519-548.
    • (2010) Pharmacol Ther , vol.128 , pp. 519-548
    • Clark, I.A.1    Alleva, L.M.2    Vissel, B.3
  • 18
    • 52049088941 scopus 로고    scopus 로고
    • A beta (1-42) reduces synapse number and inhibits neurite outgrowth in primary cortical and hippocampal neurons: A quantitative analysis
    • Evans NA, Facci L, Owen DE, Soden PE, Burbidge SA, Prinjha RK, et al. A beta (1-42) reduces synapse number and inhibits neurite outgrowth in primary cortical and hippocampal neurons: a quantitative analysis. J Neurosci Meth 2008; 175: 96-103.
    • (2008) J Neurosci Meth , vol.175 , pp. 96-103
    • Evans, N.A.1    Facci, L.2    Owen, D.E.3    Soden, P.E.4    Burbidge, S.A.5    Prinjha, R.K.6
  • 19
    • 67651089814 scopus 로고    scopus 로고
    • Long-term exposure to high corticosterone levels inducing a decrease of adenylate kinase 1 activity
    • Zhao YN, Shen J, Su H, Huang YF, Xing DM, Du LJ. Long-term exposure to high corticosterone levels inducing a decrease of adenylate kinase 1 activity. Tsinghua Sci Tech 2009; 14: 519-527.
    • (2009) Tsinghua Sci Tech , vol.14 , pp. 519-527
    • Zhao, Y.N.1    Shen, J.2    Su, H.3    Huang, Y.F.4    Xing, D.M.5    Du, L.J.6
  • 20
    • 0030793965 scopus 로고    scopus 로고
    • Miningeal blood flow by incomplete reansient cerebral ischemia reperfusion and the effect of nimodipine in mice
    • Du LJ, Yu L, Ma LY, Sun SM, Jin W. Miningeal blood flow by incomplete reansient cerebral ischemia reperfusion and the effect of nimodipine in mice. Chin Pharmacol Bull 1997; 13: 223-226.
    • (1997) Chin Pharmacol Bull , vol.13 , pp. 223-226
    • Du, L.J.1    Yu, L.2    Ma, L.Y.3    Sun, S.M.4    Jin, W.5
  • 22
    • 39149117362 scopus 로고    scopus 로고
    • Immunosuppression after traumatic or ischemic CNS damage: It is neuroprotective and illuminates the role of microglial cells
    • Hailer NP. Immunosuppression after traumatic or ischemic CNS damage: it is neuroprotective and illuminates the role of microglial cells. Prog Neurobiol 2008; 84: 211-233.
    • (2008) Prog Neurobiol , vol.84 , pp. 211-233
    • Hailer, N.P.1
  • 25
    • 68549132270 scopus 로고    scopus 로고
    • TLR4-independent and PKR-dependent interleukin 1 receptor antagonist expression upon LPS stimulation
    • Na HY, Mazumdar K, Moon HJ, Chang S, Seong SY. TLR4-independent and PKR-dependent interleukin 1 receptor antagonist expression upon LPS stimulation. Cell Immunol 2009; 259: 33-40.
    • (2009) Cell Immunol , vol.259 , pp. 33-40
    • Na, H.Y.1    Mazumdar, K.2    Moon, H.J.3    Chang, S.4    Seong, S.Y.5
  • 26
    • 27944438159 scopus 로고    scopus 로고
    • Kinetic difference of baicalin in rat blood and cerebral nuclei after intravenous administration of Scutellariae Radix extract
    • Zhang L, Xing DM, Wang W, Wang R, Du LJ. Kinetic difference of baicalin in rat blood and cerebral nuclei after intravenous administration of Scutellariae Radix extract. J Ethnopharmacol 2006; 103: 120-125.
    • (2006) J Ethnopharmacol , vol.103 , pp. 120-125
    • Zhang, L.1    Xing, D.M.2    Wang, W.3    Wang, R.4    Du, L.J.5
  • 27
    • 33749152085 scopus 로고    scopus 로고
    • Toll-like receptors: From the discovery of NF-κB to new insights into transcriptional regulations in innate immunity
    • Doyle SL, O'Neill LA. Toll-like receptors: From the discovery of NF-κB to new insights into transcriptional regulations in innate immunity. Biochem Pharmacol 2006; 72: 1102-1113.
    • (2006) Biochem Pharmacol , vol.72 , pp. 1102-1113
    • Doyle, S.L.1    O'Neill, L.A.2
  • 28
    • 68649111238 scopus 로고    scopus 로고
    • TLR4-mediated MyD88-dependent signaling pathway is activated by cerebral ischemia-reperfusion in cortex in mice
    • Gao Y, Fang XB, Tong Y, Liu YL, Zhang BH. TLR4-mediated MyD88-dependent signaling pathway is activated by cerebral ischemia-reperfusion in cortex in mice. Biomed Pharmacother 2009; 63: 442-450.
    • (2009) Biomed Pharmacother , vol.63 , pp. 442-450
    • Gao, Y.1    Fang, X.B.2    Tong, Y.3    Liu, Y.L.4    Zhang, B.H.5
  • 29
    • 0035524488 scopus 로고    scopus 로고
    • Toll-like receptors and innate immunity
    • Ruslan M. Toll-like receptors and innate immunity. Nat Rev Immunol 2001; 1:135-145.
    • (2001) Nat Rev Immunol , vol.1 , pp. 135-145
    • Ruslan, M.1
  • 30
    • 0036467357 scopus 로고    scopus 로고
    • In vivo expression of toll-like receptor 2 and 4 by renal epithelial cells: IFN-γ and TNF-α, ediated up-regulation during inflammation
    • Wolfs TG, Buurman WA, van Schadewijk A, de Vries B, Daemen MA, Hiemstra PS, et al. In vivo expression of toll-like receptor 2 and 4 by renal epithelial cells: IFN-γ and TNF-α, ediated up-regulation during inflammation. J Immunol 2002; 168: 1286-1293.
    • (2002) J Immunol , vol.168 , pp. 1286-1293
    • Wolfs, T.G.1    Buurman, W.A.2    van Schadewijk, A.3    de Vries, B.4    Daemen, M.A.5    Hiemstra, P.S.6
  • 31
    • 77955472748 scopus 로고    scopus 로고
    • Baicalin attenuates inflammation by inhibiting NF-kB activation in cigarette smoke induced inflammatory models
    • Zeng LX, Dong JC, Yu WQ, Huang JH, Liu BJ, Feng XT. Baicalin attenuates inflammation by inhibiting NF-kB activation in cigarette smoke induced inflammatory models. Pulm Pharmacol Ther 2010; 23: 411-419.
    • (2010) Pulm Pharmacol Ther , vol.23 , pp. 411-419
    • Zeng, L.X.1    Dong, J.C.2    Yu, W.Q.3    Huang, J.H.4    Liu, B.J.5    Feng, X.T.6
  • 32
    • 60949108812 scopus 로고    scopus 로고
    • Differential regulation of toll-like receptor mRNAs in amyloid plaque-associated brain tissue of aged APP23 transgenic mice
    • Frank S, Copanaki E, Burbach GJ, Müller UC, Deller T. Differential regulation of toll-like receptor mRNAs in amyloid plaque-associated brain tissue of aged APP23 transgenic mice. Neurosci Lett 2009; 453: 41-44.
    • (2009) Neurosci Lett , vol.453 , pp. 41-44
    • Frank, S.1    Copanaki, E.2    Burbach, G.J.3    Müller, U.C.4    Deller, T.5
  • 33
    • 84872430603 scopus 로고    scopus 로고
    • Screening of innate immune receptors in neurodegenerative diseases: A similar pattern
    • Letiembre M, Liu Y, Walter S, Hao W, Pfander T, Wrede A, et al. Screening of innate immune receptors in neurodegenerative diseases: a similar pattern. Neurochem 2010; 114: 462-474.
    • (2010) Neurochem , vol.114 , pp. 462-474
    • Letiembre, M.1    Liu, Y.2    Walter, S.3    Hao, W.4    Pfander, T.5    Wrede, A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.