-
1
-
-
0023664609
-
An enzyme(s) that converts glutaminyl-peptides into pyroglutamyl- peptides. Presence in pituitary, brain, adrenal medulla, and lymphocytes
-
Busby, W. H., Quackenbush, G. E., Humm, J., Youngblood, W. W. and Kizer, J. S. (1987) An enzyme(s) that converts glutaminyl-peptides into pyroglutamyl-peptides. Presence in pituitary, brain, adrenal medulla, and lymphocytes. J. Biol. Chem. 262, 8532-8536
-
(1987)
J. Biol. Chem.
, vol.262
, pp. 8532-8536
-
-
Busby, W.H.1
Quackenbush, G.E.2
Humm, J.3
Youngblood, W.W.4
Kizer, J.S.5
-
3
-
-
23244450070
-
Cloning, expression, characterization, and crystallization of a glutaminyl cyclase from human bone marrow: A single zinc metalloenzyme
-
Huang, K. F., Liu, Y. L. and Wang, A. H. (2005) Cloning, expression, characterization, and crystallization of a glutaminyl cyclase from human bone marrow: a single zinc metalloenzyme. Protein Expression Purif. 43, 65-72
-
(2005)
Protein Expression Purif.
, vol.43
, pp. 65-72
-
-
Huang, K.F.1
Liu, Y.L.2
Wang, A.H.3
-
4
-
-
0346728541
-
Substrate specificity of glutaminyl cyclases from plants and animals
-
DOI 10.1515/BC.2003.175
-
Schilling, S., Manhart, S., Hoffmann, T., Ludwig, H. H., Wasternack, C. and Demuth, H. U. (2003) Substrate specificity of glutaminyl cyclases from plants and animals. Biol. Chem. 384, 1583-1592 (Pubitemid 38054881)
-
(2003)
Biological Chemistry
, vol.384
, Issue.12
, pp. 1583-1592
-
-
Schilling, S.1
Manhart, S.2
Hoffmann, T.3
Ludwig, H.-H.4
Wasternack, C.5
Demuth, H.-U.6
-
5
-
-
0017735980
-
Forces and structural limitations of binding of thyrotrophin releasing factor to the thyrotrophin releasing receptor: The pyroglutamic acid moiety
-
Goren, H. J., Bauce, L. G. and Vale, W. (1977) Forces and structural limitations of binding of thyrotrophin-releasing factor to thyrotrophin- releasing receptor: the pyroglutamic acid moiety. Mol. Pharmacol. 13, 606-614 (Pubitemid 8148877)
-
(1977)
Molecular Pharmacology
, vol.13
, Issue.4
, pp. 606-614
-
-
Goren, H.J.1
Bauce, L.G.2
-
6
-
-
0032497366
-
Functional comparison of two human monocyte chemotactic protein-2 isoforms, role of the amino-terminal pyroglutamic acid and processing by CD26/dipeptidyl peptidase IV
-
DOI 10.1021/bi980497d
-
Van Coillie, E., Proost, P., Van Aelst, I., Struyf, S., Polfliet, M., De Meester, I., Harvey, D. J., Van Damme, J. and Opdenakker, G. (1998) Functional comparison of two human monocyte chemotactic protein-2 isoforms, role of the amino-terminal pyroglutamic acid and processing by CD26/dipeptidyl peptidase IV. Biochemistry 37, 12672-12680 (Pubitemid 28427552)
-
(1998)
Biochemistry
, vol.37
, Issue.36
, pp. 12672-12680
-
-
Van Coillie, E.1
Proost, P.2
Van Aelst, I.3
Struyf, S.4
Polfliet, M.5
De Meester, I.6
Harvey, D.J.7
Van Damme, J.8
Opdenakker, G.9
-
7
-
-
44349133269
-
Isolation of an isoenzyme of human glutaminyl cyclase: Retention in the Golgi complex suggests involvement in the protein maturation machinery
-
Cynis, H., Rahfeld, J. U., Stephan, A., Kehlen, A., Koch, B., Wermann, M., Demuth, H. U. and Schilling, S. (2008) Isolation of an isoenzyme of human glutaminyl cyclase: retention in the Golgi complex suggests involvement in the protein maturation machinery. J. Mol. Biol. 379, 966-980
-
(2008)
J. Mol. Biol.
, vol.379
, pp. 966-980
-
-
Cynis, H.1
Rahfeld, J.U.2
Stephan, A.3
Kehlen, A.4
Koch, B.5
Wermann, M.6
Demuth, H.U.7
Schilling, S.8
-
8
-
-
79953297940
-
Structures of human Golgi-resident glutaminyl cyclase and its complexes with inhibitors reveal a large loop movement upon inhibitor binding
-
Huang, K. F., Liaw, S. S., Huang, W. L., Chia, C. Y., Lo, Y. C., Chen, Y. L. and Wang, A. H. J. (2011) Structures of human Golgi-resident glutaminyl cyclase and its complexes with inhibitors reveal a large loop movement upon inhibitor binding. J. Biol. Chem. 286, 12439-12449
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 12439-12449
-
-
Huang, K.F.1
Liaw, S.S.2
Huang, W.L.3
Chia, C.Y.4
Lo, Y.C.5
Chen, Y.L.6
Wang, A.H.J.7
-
9
-
-
2542463940
-
Improved determination of bovine glutaminyl cyclase activity using precolumn derivatization and reversed-phase high-performance liquid chromatography with ultraviolet detection
-
DOI 10.1016/j.jchromb.2004.03.040, PII S1570023204002818
-
Chikuma, T., Taguchi, K., Yamaguchi, M., Hojo, H. and Kato, T. (2004) Improved determination of bovine glutaminyl cyclase activity using precolumn derivatization and reversed-phase high-performance liquid chromatography with ultraviolet detection. J. Chromatogr. B Anal. Technol. Biomed. Life Sci. 806, 113-118 (Pubitemid 38686497)
-
(2004)
Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences
, vol.806
, Issue.2
, pp. 113-118
-
-
Chikuma, T.1
Taguchi, K.2
Yamaguchi, M.3
Hojo, H.4
Kato, T.5
-
10
-
-
33845735043
-
Epigenetic silencing of novel tumor suppressors in malignant melanoma
-
DOI 10.1158/0008-5472.CAN-06-1274
-
Muthusamy, V., Duraisamy, S., Bradbury, C. M., Hobbs, C., Curley, D. P., Nelson, B. and Bosenberg, M. (2006) Epigenetic silencing of novel tumor suppressors in malignant melanoma. Cancer Res. 66, 11187-11193 (Pubitemid 46009946)
-
(2006)
Cancer Research
, vol.66
, Issue.23
, pp. 11187-11193
-
-
Muthusamy, V.1
Duraisamy, S.2
Bradbury, C.M.3
Hobbs, C.4
Curley, D.P.5
Nelson, B.6
Bosenberg, M.7
-
11
-
-
53549099647
-
Glutaminyl cyclase inhibition attenuates pyroglutamate Aβ and Alzheimer's disease-like pathology
-
Schilling, S., Zeitschel, U., Hoffmann, T., Heiser, U., Francke, M., Kehlen, A., Holzer, M., Hutter-Paier, B., Prokesch, M., Windisch, M. et al. (2008) Glutaminyl cyclase inhibition attenuates pyroglutamate Aβ and Alzheimer's disease-like pathology. Nat. Med. 14, 1106-1111
-
(2008)
Nat. Med.
, vol.14
, pp. 1106-1111
-
-
Schilling, S.1
Zeitschel, U.2
Hoffmann, T.3
Heiser, U.4
Francke, M.5
Kehlen, A.6
Holzer, M.7
Hutter-Paier, B.8
Prokesch, M.9
Windisch, M.10
-
12
-
-
16644383500
-
Association of multiple nucleotide variations in the pituitary glutaminyl cyclase gene (QPCT) with low radial BMD in adult women
-
DOI 10.1359/JBMR.040324
-
Ezura, Y., Kajita, M., Ishida, R., Yoshida, S., Yoshida, H., Suzuki, T., Hosoi, T., Inoue, S., Shiraki, M., Orimo, H. and Emi, M. (2004) Association of multiple nucleotide variations in the pituitary glutaminyl cyclase gene (QPCT) with low radial BMD in adult women. J. Bone Miner. Res. 19, 1296-1301 (Pubitemid 41094371)
-
(2004)
Journal of Bone and Mineral Research
, vol.19
, Issue.8
, pp. 1296-1301
-
-
Ezura, Y.1
Kajita, M.2
Ishida, R.3
Yoshida, S.4
Yoshida, H.5
Suzuki, T.6
Hosoi, T.7
Inoue, S.8
Shiraki, M.9
Orimo, H.10
Emi, M.11
-
13
-
-
30744449552
-
Peripheral blood gene expression profiling in rheumatoid arthritis
-
DOI 10.1038/sj.gene.6364209, PII 6364209
-
Batliwalla, F. M., Baechler, E. C., Xiao, X., Li, W., Balasubramanian, S., Khalili, H., Damle, A., Ortmann, W., Perrone, A., Kantor, A. B. et al. (2005) Peripheral blood gene expression profiling in rheumatoid arthritis. Genes Immun. 6, 388-397 (Pubitemid 43090514)
-
(2005)
Genes and Immunity
, vol.6
, Issue.5
, pp. 388-397
-
-
Batliwalla, F.M.1
Baechler, E.C.2
Xiao, X.3
Li, W.4
Balasubramanian, S.5
Khalili, H.6
Damle, A.7
Ortmann, W.A.8
Perrone, A.9
Kantor, A.B.10
Gulko, P.S.11
Kern, M.12
Furie, R.13
Behrens, T.W.14
Gregersen, P.K.15
-
14
-
-
0028855851
-
N3(pE), in senile plaques
-
N3(pE), in senile plaques. Neuron 14, 457-466
-
(1995)
Neuron
, vol.14
, pp. 457-466
-
-
Saido, T.C.1
Iwatsubo, T.2
Mann, D.M.3
Shimada, H.4
Ihara, Y.5
Kawashima, S.6
-
15
-
-
0034710784
-
Amyloid β protein starting pyroglutamate at position 3 is a major component of the amyloid deposits in the Alzheimer's disease brain
-
Harigaya, Y., Saido, T. C., Eckman, C. B., Prada, C. M., Shoji, M. and Younkin, S. G. (2000) Amyloid β protein starting pyroglutamate at position 3 is a major component of the amyloid deposits in the Alzheimer's disease brain. Biochem. Biophys. Res. Commun. 276, 422-427
-
(2000)
Biochem. Biophys. Res. Commun.
, vol.276
, pp. 422-427
-
-
Harigaya, Y.1
Saido, T.C.2
Eckman, C.B.3
Prada, C.M.4
Shoji, M.5
Younkin, S.G.6
-
16
-
-
48249145775
-
Inhibition of glutaminyl cyclase prevents pGlu-Aβ formation after intracortical/hippocampal microinjection in vivo/in situ
-
Schilling, S., Appl, T., Hoffmann, T., Cynis, H., Schulz, K., Jagla, W., Friedrich, D., Wermann, M., Buchholz, M., Heiser, U. et al. (2008) Inhibition of glutaminyl cyclase prevents pGlu-Aβ formation after intracortical/ hippocampal microinjection in vivo/in situ. J. Neurochem. 106, 1225-1236
-
(2008)
J. Neurochem.
, vol.106
, pp. 1225-1236
-
-
Schilling, S.1
Appl, T.2
Hoffmann, T.3
Cynis, H.4
Schulz, K.5
Jagla, W.6
Friedrich, D.7
Wermann, M.8
Buchholz, M.9
Heiser, U.10
-
17
-
-
0348010383
-
Identification of human glutaminyl cyclase as a metalloenzyme: Potent inhibition by imidazole derivatives and heterocyclic chelators
-
DOI 10.1074/jbc.M309077200
-
Schilling, S., Niestroj, A. J., Rahfeld, J. U., Hoffmann, T., Wermann, M., Zunkel, K., Wasternack, C. and Demuth, H. U. (2003) Identification of human glutaminyl cyclase as a metalloenzyme. Potent inhibition by imidazole derivatives and heterocyclic chelators. J. Biol. Chem. 278, 49773-49779 (Pubitemid 37548810)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.50
, pp. 49773-49779
-
-
Schilling, S.1
Niestroj, A.J.2
Rahfeld, J.-U.3
Hoffmann, T.4
Wermann, M.5
Zunkel, K.6
Wasternack, C.7
Demuth, H.-U.8
-
18
-
-
31544474368
-
The first potent inhibitors for human glutaminyl cyclase: Synthesis and structure-activity relationship
-
DOI 10.1021/jm050756e
-
Buchholz, M., Heiser, U., Schilling, S., Niestroj, A. J., Zunkel, K. and Demuth, H. U. (2006) The first potent inhibitors for human glutaminyl cyclase: synthesis and structure - activity relationship. J. Med. Chem. 49, 664-677 (Pubitemid 43157496)
-
(2006)
Journal of Medicinal Chemistry
, vol.49
, Issue.2
, pp. 664-677
-
-
Buchholz, M.1
Heiser, U.2
Schilling, S.3
Niestroj, A.J.4
Zunkel, K.5
Demuth, H.-U.6
-
19
-
-
33749615367
-
Inhibition of glutaminyl cyclase alters pyroglutamate formation in mammalian cells
-
DOI 10.1016/j.bbapap.2006.08.003, PII S1570963906002755
-
Cynis, H., Schilling, S., Bodnar, M., Hoffmann, T., Heiser, U., Saido, T. C. and Demuth, H. U. (2006) Inhibition of glutaminyl cyclase alters pyroglutamate formation in mammalian cells. Biochim. Biophys. Acta 1764, 1618-1625 (Pubitemid 44548538)
-
(2006)
Biochimica et Biophysica Acta - Proteins and Proteomics
, vol.1764
, Issue.10
, pp. 1618-1625
-
-
Cynis, H.1
Schilling, S.2
Bodnar, M.3
Hoffmann, T.4
Heiser, U.5
Saido, T.C.6
Demuth, H.-U.7
-
20
-
-
0029740137
-
Chemokines: A superfamily of chemotactic cytokines
-
Sozzani, S., Locati, M., Allavena, P., Van Damme, J. and Mantovani, A. (1996) Chemokines: a superfamily of chemotactic cytokines. Int. J. Clin. Lab. Res. 26, 69-82 (Pubitemid 26310342)
-
(1996)
International Journal of Clinical and Laboratory Research
, vol.26
, Issue.2
, pp. 69-82
-
-
Sozzani, S.1
Locati, M.2
Allavena, P.3
Van Damme, J.4
Mantovani, A.5
-
21
-
-
53149136171
-
Chemotaxis, chemokine receptors and human disease
-
Jin, T., Xu, X. H. and Hereld, D. (2008) Chemotaxis, chemokine receptors and human disease. Cytokine 44, 1-8
-
(2008)
Cytokine
, vol.44
, pp. 1-8
-
-
Jin, T.1
Xu, X.H.2
Hereld, D.3
-
22
-
-
0030061595
-
Human monocyte chemotactic proteins-2 and -3: Structural and functional comparison with MCP-1
-
Proost, P., Wuyts, A. and VanDamme, J. (1996) Human monocyte chemotactic proteins-2 and -3: structural and functional comparison with MCP-1. J. Leukocyte Biol. 59, 67-74 (Pubitemid 26054592)
-
(1996)
Journal of Leukocyte Biology
, vol.59
, Issue.1
, pp. 67-74
-
-
Proost, P.1
Wuyts, A.2
Van Damme, J.3
-
23
-
-
0028952523
-
Antagonists of monocyte chemoattractant protein-1 identified by modification of functionally critical Nh2-terminal residues
-
Gong, J. H. and Clark-Lewis, I. (1995) Antagonists of monocyte chemoattractant protein-1 identified by modification of functionally critical Nh2-terminal residues. J. Exp. Med. 181, 631-640
-
(1995)
J. Exp. Med.
, vol.181
, pp. 631-640
-
-
Gong, J.H.1
Clark-Lewis, I.2
-
24
-
-
0032522660
-
Posttranslational modifications affect the activity of the human monocyte chemotactic proteins MCP-1 and MCP-2: Identification of MCP-2(6-76) as a natural chemokine inhibitor
-
Proost, P., Struyf, S., Couvreur, M., Lenaerts, J. P., Conings, R., Menten, P., Verhaert, P., Wuyts, A. and Van Damme, J. (1998) Posttranslational modifications affect the activity of the human monocyte chemotactic proteins MCP-1 and MCP-2: identification of MCP-2(6-76) as a natural chemokine inhibitor. J. Immunol. 160, 4034-4041 (Pubitemid 28176113)
-
(1998)
Journal of Immunology
, vol.160
, Issue.8
, pp. 4034-4041
-
-
Proost, P.1
Struyf, S.2
Couvreur, M.3
Lenaerts, J.-P.4
Conings, R.5
Menten, P.6
Verhaert, P.7
Wuyts, A.8
Van Damme, J.9
-
25
-
-
0029131699
-
A dominant-negative inhibitor indicates that monocyte chemoattractant protein-1 functions as a dimer
-
Zhang, Y. J. and Rollins, B. J. (1995) A dominant-negative inhibitor indicates that monocyte chemoattractant protein-1 functions as a dimer. Mol. Cell. Biol. 15, 4851-4855
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 4851-4855
-
-
Zhang, Y.J.1
Rollins, B.J.2
-
26
-
-
0036535456
-
Continuous spectrometric assays for glutaminyl cyclase activity
-
DOI 10.1006/abio.2001.5560
-
Schilling, S., Hoffmann, T., Wermann, M., Heiser, U., Wasternack, C. and Demuth, H. U. (2002) Continuous spectrometric assays for glutaminyl cyclase activity. Anal. Biochem. 303, 49-56 (Pubitemid 34271104)
-
(2002)
Analytical Biochemistry
, vol.303
, Issue.1
, pp. 49-56
-
-
Schilling, S.1
Hoffmann, T.2
Wermann, M.3
Heiser, U.4
Wasternack, C.5
Demuth, H.-U.6
-
27
-
-
3543012707
-
Crystallography & NMR system: A new software suite for macromolecular structure determination
-
Brunger, A. T., Adams, P. D., Clore, G. M., DeLano, W. L., Gros, P., Grosse-Kunstleve, R. W., Jiang, J. S., Kuszewski, J., Nilges, M., Pannu, N. S. et al. (1998) Crystallography & NMR system: a new software suite for macromolecular structure determination. Acta Crystallogr. Sect. D Biol. Crystallogr. 54, 905-921
-
(1998)
Acta Crystallogr. Sect. D Biol. Crystallogr.
, vol.54
, pp. 905-921
-
-
Brunger, A.T.1
Adams, P.D.2
Clore, G.M.3
DeLano, W.L.4
Gros, P.5
Grosse-Kunstleve, R.W.6
Jiang, J.S.7
Kuszewski, J.8
Nilges, M.9
Pannu, N.S.10
-
28
-
-
0026610767
-
Assessment of protein models with three-dimensional profiles
-
Luthy, R., Bowie, J. U. and Eisenberg, D. (1992) Assessment of protein models with three-dimensional profiles. Nature 356, 83-85
-
(1992)
Nature
, vol.356
, pp. 83-85
-
-
Luthy, R.1
Bowie, J.U.2
Eisenberg, D.3
-
29
-
-
0027169515
-
Main-chain bond lengths and bond angles in protein structures
-
DOI 10.1006/jmbi.1993.1351
-
Laskowski, R. A., Moss, D. S. and Thornton, J. M. (1993) Main-chain bond lengths and bond angles in protein structures. J. Mol. Biol. 231, 1049-1067 (Pubitemid 23209879)
-
(1993)
Journal of Molecular Biology
, vol.231
, Issue.4
, pp. 1049-1067
-
-
Laskowski, R.A.1
Moss, D.S.2
Thornton, J.M.3
-
30
-
-
24944521480
-
Crystal structures of human glutaminyl cyclase, an enzyme responsible for protein N-terminal pyroglutamate formation
-
Huang, K. F., Liu, Y. L., Cheng, W. J., Ko, T. P. and Wang, A. H. (2005) Crystal structures of human glutaminyl cyclase, an enzyme responsible for protein N-terminal pyroglutamate formation. Proc. Natl. Acad. Sci. U.S.A. 102, 13117-13122
-
(2005)
Proc. Natl. Acad. Sci. U.S.A.
, vol.102
, pp. 13117-13122
-
-
Huang, K.F.1
Liu, Y.L.2
Cheng, W.J.3
Ko, T.P.4
Wang, A.H.5
-
31
-
-
0032833999
-
Identification of residues in the monocyte chemotactic protein-1 that contact the MCP-1 receptor, CCR2
-
Hemmerich, S., Paavola, C., Bloom, A., Bhakta, S., Freedman, R., Grunberger, D., Krstenansky, J., Lee, S., McCarley, D., Mulkins, M. et al. (1999) Identification of residues in the monocyte chemotactic protein-1 that contact the MCP-1 receptor, CCR2. Biochemistry 38, 13013-13025
-
(1999)
Biochemistry
, vol.38
, pp. 13013-13025
-
-
Hemmerich, S.1
Paavola, C.2
Bloom, A.3
Bhakta, S.4
Freedman, R.5
Grunberger, D.6
Krstenansky, J.7
Lee, S.8
McCarley, D.9
Mulkins, M.10
-
32
-
-
42949171833
-
Signalling, inflammation and arthritis: NF-κB and its relevance to arthritis and inflammation
-
DOI 10.1093/rheumatology/kem298
-
Simmonds, R. E. and Foxwell, B. M. (2008) Signalling, inflammation and arthritis: NF-κB and its relevance to arthritis and inflammation. Rheumatology 47, 584-590 (Pubitemid 351619194)
-
(2008)
Rheumatology
, vol.47
, Issue.5
, pp. 584-590
-
-
Simmonds, R.E.1
Foxwell, B.M.2
-
33
-
-
0028359960
-
Induction of monocyte chemotactic proteins MCP-1 and MCP-2 in human fibroblasts and leukocytes by cytokines and cytokine inducers: Chemical synthesis of MCP-2 and development of a specific RIA
-
Van Damme, J., Proost, P., Put, W., Arens, S., Lenaerts, J. P., Conings, R., Opdenakker, G., Heremans, H. and Billiau, A. (1994) Induction of monocyte chemotactic proteins MCP-1 and MCP-2 in human fibroblasts and leukocytes by cytokines and cytokine inducers. Chemical synthesis of MCP-2 and development of a specific RIA. J. Immunol. 152, 5495-5502 (Pubitemid 24152999)
-
(1994)
Journal of Immunology
, vol.152
, Issue.11
, pp. 5495-5502
-
-
Van Damme, J.1
Proost, P.2
Put, W.3
Arens, S.4
Lenaerts, J.-P.5
Conings, R.6
Opdenakker, G.7
Heremans, H.8
Billiau, A.9
-
34
-
-
28044433451
-
Protein posttranslational modifications: The chemistry of proteome diversifications
-
DOI 10.1002/anie.200501023
-
Walsh, C. T., Garneau-Tsodikova, S. and Gatto, G. J. (2005) Protein posttranslational modifications: the chemistry of proteome diversifications. Angew. Chem. Int. Ed. 44, 7342-7372 (Pubitemid 41689988)
-
(2005)
Angewandte Chemie - International Edition
, vol.44
, Issue.45
, pp. 7342-7372
-
-
Walsh, C.T.1
Garneau-Tsodikova, S.2
Gatto Jr., G.J.3
-
35
-
-
0014666196
-
Identity of chemical and hormonal properties of thyrotropin releasing hormone and pyroglutamyl-histidyl-proline amide
-
Boler, J., Enzmann, F., Folkers, K., Bowers, C. Y. and Schally, A. V. (1969) Identity of chemical and hormonal properties of thyrotropin releasing hormone and pyroglutamyl-histidyl-proline amide. Biochem. Biophys. Res. Commun. 37, 705-710
-
(1969)
Biochem. Biophys. Res. Commun.
, vol.37
, pp. 705-710
-
-
Boler, J.1
Enzmann, F.2
Folkers, K.3
Bowers, C.Y.4
Schally, A.V.5
-
36
-
-
0028785040
-
Pro-thyrotropin-releasing hormone processing by recombinant Pc1
-
Nillni, E. A., Friedman, T. C., Todd, R. B., Birch, N. P., Loh, Y. P. and Jackson, I. M. D. (1995) Pro-thyrotropin-releasing hormone processing by recombinant Pc1. J. Neurochem. 65, 2462-2472
-
(1995)
J. Neurochem.
, vol.65
, pp. 2462-2472
-
-
Nillni, E.A.1
Friedman, T.C.2
Todd, R.B.3
Birch, N.P.4
Loh, Y.P.5
Jackson, I.M.D.6
-
37
-
-
0034700312
-
Complete crystal structure of monocyte chemotactic protein-2, a CC chemokine that interacts with multiple receptors
-
Blaszczyk, J., Van Coillie, E., Proost, P., Van Damme, J., Opdenakker, G., Bujacz, G. D., Wang, J. M. and Ji, X. (2000) Complete crystal structure of monocyte chemotactic protein-2, a CC chemokine that interacts with multiple receptors. Biochemistry 39, 14075-14081
-
(2000)
Biochemistry
, vol.39
, pp. 14075-14081
-
-
Blaszczyk, J.1
Van Coillie, E.2
Proost, P.3
Van Damme, J.4
Opdenakker, G.5
Bujacz, G.D.6
Wang, J.M.7
Ji, X.8
-
38
-
-
0019784255
-
Pyroglutamic acid. Non-metabolic formation, function in proteins and peptides, and characteristics of the enzymes effecting its removal
-
Abraham, G. N. and Podell, D. N. (1981) Pyroglutamic acid. Non-metabolic formation, function in proteins and peptides, and characteristics of the enzymes effecting its removal. Mol. Cell. Biochem. 38, 181-190 (Pubitemid 12250053)
-
(1981)
Molecular and Cellular Biochemistry
, vol.38
, Issue.1
, pp. 181-190
-
-
Abraham, G.N.1
Podell, D.M.2
-
39
-
-
0031026207
-
The structure of MCP-1 in two crystal forms provides a rare example of variable quaternary interactions
-
DOI 10.1038/nsb0197-64
-
Lubkowski, J., Bujacz, G., Boque, L., Domaille, P. J., Handel, T. M. and Wlodawer, A. (1997) The structure of MCP-1 in two crystal forms provides a rare example of variable quaternary interactions. Nat. Struct. Biol. 4, 64-69 (Pubitemid 27020927)
-
(1997)
Nature Structural Biology
, vol.4
, Issue.1
, pp. 64-69
-
-
Lubkowski, J.1
Bujacz, G.2
Boque, L.3
Domaille, P.J.4
Handel, T.M.5
Wlodawer, A.6
-
40
-
-
0030993344
-
1H two-dimensional NMR spectroscopy
-
DOI 10.1021/bi9627929
-
Meunier, S., Bernassau, J. M., Guillemot, J. C., Ferrara, P. and Darbon, H. (1997) Determination of the three-dimensional structure of CC chemokine monocyte chemoattractant protein 3 by 1H two-dimensional NMR spectroscopy. Biochemistry 36, 4412-4422 (Pubitemid 27180287)
-
(1997)
Biochemistry
, vol.36
, Issue.15
, pp. 4412-4422
-
-
Meunier, S.1
Bernassau, J.-M.2
Guillemot, J.-C.3
Ferrara, P.4
Darbon, H.5
-
41
-
-
40449126150
-
Structure of human monocyte chemoattractant protein 4 (MCP-4/CCL13)
-
DOI 10.1107/S0907444907066164, PII S0907444907066164
-
Barinka, C., Prahl, A. and Lubkowski, J. (2008) Structure of human monocyte chemoattractant protein 4 (MCP-4/CCL13). Acta Crystallogr. Sect. D Biol. Crystallogr. 64, 273-278 (Pubitemid 351348053)
-
(2008)
Acta Crystallographica Section D: Biological Crystallography
, vol.64
, Issue.3
, pp. 273-278
-
-
Barinka, C.1
Prahl, A.2
Lubkowski, J.3
-
42
-
-
0029010408
-
Structure-activity relationships of chemokines
-
Clark-Lewis, I., Kim, K. S., Rajarathnam, K., Gong, J. H., Dewald, B., Moser, B., Baggiolini, M. and Sykes, B. D. (1995) Structure-activity relationships of chemokines. J. Leukocyte Biol. 57, 703-711
-
(1995)
J. Leukocyte Biol.
, vol.57
, pp. 703-711
-
-
Clark-Lewis, I.1
Kim, K.S.2
Rajarathnam, K.3
Gong, J.H.4
Dewald, B.5
Moser, B.6
Baggiolini, M.7
Sykes, B.D.8
-
43
-
-
79954572883
-
Glutaminyl cyclase knock-out mice exhibit slight hypothyroidism but no hypogonadism: Implications for enzyme function and drug development
-
Schilling, S., Kohlmann, S., Bäuscher, C., Sedlmeier, R., Koch, B., Eichentopf, R., Becker, A., Cynis, H., Hoffmann, T., Berg, S. et al. (2011) Glutaminyl cyclase knock-out mice exhibit slight hypothyroidism but no hypogonadism: implications for enzyme function and drug development. J. Biol. Chem. 286, 14199-14208
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 14199-14208
-
-
Schilling, S.1
Kohlmann, S.2
Bäuscher, C.3
Sedlmeier, R.4
Koch, B.5
Eichentopf, R.6
Becker, A.7
Cynis, H.8
Hoffmann, T.9
Berg, S.10
-
44
-
-
80052288497
-
The isoenzyme of glutaminyl cyclase is an important regulator of monocyte infiltration under inflammatory conditions
-
Cynis, H., Hoffmann, T., Friedrich, D., Kehlen, A., Gans, K., Kleinschmidt, M., Rahfeld, J. U., Wolf, R., Wermann, M., Stephan, A. et al. (2011) The isoenzyme of glutaminyl cyclase is an important regulator of monocyte infiltration under inflammatory conditions. EMBO Mol. Med. 3, 545-558
-
(2011)
EMBO Mol. Med.
, vol.3
, pp. 545-558
-
-
Cynis, H.1
Hoffmann, T.2
Friedrich, D.3
Kehlen, A.4
Gans, K.5
Kleinschmidt, M.6
Rahfeld, J.U.7
Wolf, R.8
Wermann, M.9
Stephan, A.10
-
45
-
-
33646078924
-
Therapeutic potential of cytokine and chemokine antagonists in cancer therapy
-
Yan, L., Anderson, G. M., DeWitte, M. and Nakada, M. T. (2006) Therapeutic potential of cytokine and chemokine antagonists in cancer therapy. Eur. J. Cancer 42, 793-802
-
(2006)
Eur. J. Cancer
, vol.42
, pp. 793-802
-
-
Yan, L.1
Anderson, G.M.2
DeWitte, M.3
Nakada, M.T.4
-
46
-
-
68449085753
-
III. Angiogenesis: Complexity of tumor vasculature and microenvironment
-
Furuya, M., Yonemitsu, Y. and Aoki, I. (2009) III. Angiogenesis: complexity of tumor vasculature and microenvironment. Curr. Pharm. Des. 15, 1854-1867
-
(2009)
Curr. Pharm. Des.
, vol.15
, pp. 1854-1867
-
-
Furuya, M.1
Yonemitsu, Y.2
Aoki, I.3
-
47
-
-
0029802605
-
Chemokines and HIV-1 second receptors. Confluence of two fields generates optimism in AIDS research
-
DOI 10.1038/nm1296-1293
-
D'Souza, M. P. and Harden, V. A. (1996) Chemokines and HIV-1 second receptors. Confluence of two fields generates optimism in AIDS research. Nat. Med. 2, 1293-1300 (Pubitemid 26401723)
-
(1996)
Nature Medicine
, vol.2
, Issue.12
, pp. 1293-1300
-
-
D'Souza, M.P.1
Harden, V.A.2
-
48
-
-
27144465704
-
HIV chemokine receptor inhibitors as novel anti-HIV drugs
-
DOI 10.1016/j.cytogfr.2005.05.009, PII S1359610105000717, Chemokines
-
Princen, K. and Schols, D. (2005) HIV chemokine receptor inhibitors as novel anti-HIV drugs. Cytokine Growth Factor Rev. 16, 659-677 (Pubitemid 41505522)
-
(2005)
Cytokine and Growth Factor Reviews
, vol.16
, Issue.6
, pp. 659-677
-
-
Princen, K.1
Schols, D.2
|