-
2
-
-
15444380849
-
IFN-alpha enhances TLR3-mediated antiviral cytokine expression in human endothelial and epithelial cells by up-regulating TLR3 expression
-
Tissari J, Siren J, Meri S, Julkunen I, Matikainen S. IFN-alpha enhances TLR3-mediated antiviral cytokine expression in human endothelial and epithelial cells by up-regulating TLR3 expression. J Immunol. 2005;174:4289-4294. (Pubitemid 40396010)
-
(2005)
Journal of Immunology
, vol.174
, Issue.7
, pp. 4289-4294
-
-
Tissari, J.1
Siren, J.2
Meri, S.3
Julkunen, I.4
Matikainen, S.5
-
3
-
-
12444341944
-
Toll-like receptors in innate immunity
-
Takeda K, Akira S. Toll-like receptors in innate immunity. Int Immunol. 2005;17:1-14.
-
(2005)
Int Immunol
, vol.17
, pp. 1-14
-
-
Takeda, K.1
Akira, S.2
-
4
-
-
0038393016
-
IKKE and TBKI are essential components of the IRF3 signalling pathway
-
DOI 10.1038/ni921
-
Fitzgerald KA, McWhirter SM, Faia KL, Rowe DC, Latz E, Golenbock DT, et al. IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway. Nat Immunol. 2003;4:491-496. (Pubitemid 36592443)
-
(2003)
Nature Immunology
, vol.4
, Issue.5
, pp. 491-496
-
-
Fitzgerald, K.A.1
McWhirter, S.M.2
Faia, K.L.3
Rowe, D.C.4
Latz, E.5
Golenbock, D.T.6
Coyle, A.J.7
Liao, S.-M.8
Maniatis, T.9
-
5
-
-
2442642691
-
RIP1 is an essential mediator of Toll-like receptor 3-induced NF kappaB activation
-
DOI 10.1038/ni1061
-
Meylan E, Burns K, Hofmann K, Blancheteau V, Martinon F, Kelliher M, et al. RIP1 is an essential mediator of Toll-like receptor 3-induced NF-kappa B activation. Nat Immunol. 2004;5: 503-507. (Pubitemid 38660462)
-
(2004)
Nature Immunology
, vol.5
, Issue.5
, pp. 503-507
-
-
Meylan, E.1
Burns, K.2
Hofmann, K.3
Blancheteau, V.4
Martinon, F.5
Kelliher, M.6
Tschopp, J.7
-
6
-
-
0141923690
-
Toll/IL-1 receptor domain-containing adaptor inducing IFN-beta (TRIF) associates with TNF receptor-associated factor 6 and TANK-binding kinase 1, and activates two distinct transcription factors, NF-kappaB and IFN-regulatory factor-3, in the toll-like receptor signaling
-
Sato S, Sugiyama M, Yamamoto M, Watanabe Y, Kawai T, Takeda K, et al. Toll/IL-1 receptor domain-containing adaptor inducing IFN-beta (TRIF) associates with TNF receptor-associated factor 6 and TANK-binding kinase 1, and activates two distinct transcription factors, NF-kappa B and IFN-regulatory factor- 3, in the Toll-like receptor signaling. J Immunol. 2003; 171:4304-4310. (Pubitemid 37238709)
-
(2003)
Journal of Immunology
, vol.171
, Issue.8
, pp. 4304-4310
-
-
Sato, S.1
Sugiyama, M.2
Yamamoto, M.3
Watanabe, Y.4
Kawai, T.5
Takeda, K.6
Akira, S.7
-
7
-
-
33744526702
-
Inhibition of homodimerization of Toll-like receptor 4 by curcumin
-
DOI 10.1016/j.bcp.2006.03.022, PII S0006295206001936
-
Youn HS, Saitoh SI, Miyake K, Hwang DH. Inhibition of homodimerization of Toll-like receptor 4 by curcumin. Biochem Pharmacol. 2006;72:62-69. (Pubitemid 43810172)
-
(2006)
Biochemical Pharmacology
, vol.72
, Issue.1
, pp. 62-69
-
-
Youn, H.S.1
Saitoh, S.I.2
Miyake, K.3
Hwang, D.H.4
-
8
-
-
0034680145
-
Toll-like receptors in the induction of the innate immune response
-
Aderem A, Ulevitch RJ. Toll-like receptors in the induction of the innate immune response. Nature. 2000;406:782-787.
-
(2000)
Nature
, vol.406
, pp. 782-787
-
-
Aderem, A.1
Ulevitch, R.J.2
-
9
-
-
38649136299
-
LPS-induced IL-6, IL-8, VCAM-1, and ICAM-1 expression in human lymphatic endothelium
-
DOI 10.1369/jhc.7A7299.2007
-
Sawa Y, Ueki T, Hata M, Iwasawa K, Tsuruga E, Kojima H, et al. LPS-induced IL-6, IL-8, VCAM-1, and ICAM-1 expression in human lymphatic endothelium. J Histochem Cytochem. 2008;56:97-109. (Pubitemid 351170963)
-
(2008)
Journal of Histochemistry and Cytochemistry
, vol.56
, Issue.2
, pp. 97-109
-
-
Sawa, Y.1
Ueki, T.2
Hata, M.3
Iwasawa, K.4
Tsuruga, E.5
Kojima, H.6
Ishikawa, H.7
Yoshida, S.8
-
10
-
-
0035909372
-
Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3
-
DOI 10.1038/35099560
-
Alexopoulou L, Holt AC, Medzhitov R, Flavell RA. Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3. Nature. 2001;413:732-738. (Pubitemid 33009951)
-
(2001)
Nature
, vol.413
, Issue.6857
, pp. 732-738
-
-
Alexopoulou, L.1
Holt, A.C.2
Medzhitov, R.3
Flavell, R.A.4
-
11
-
-
0022411888
-
Passive immunization against cachectin/tumor necrosis factor protects mice from lethal effect of endotoxin
-
Beutler B, Milsark IW, Cerami AC. Passive immunization against cachectin/tumor necrosis factor protects mice from lethal effect of endotoxin. Science. 1985;229:869-871. (Pubitemid 16246587)
-
(1985)
Science
, vol.229
, Issue.4716
, pp. 869-871
-
-
Beutler, B.1
Milsark, I.W.2
Cerami, A.C.3
-
12
-
-
3242728901
-
Reduced atherosclerosis in MyD88-null mice links elevated serum cholesterol levels to activation of innate immunity signaling pathways
-
DOI 10.1038/nm1008
-
Bjorkbacka H, Kunjathoor VV, Moore KJ, Koehn S, Ordija CM, Lee MA, et al. Reduced atherosclerosis in MyD88-null mice links elevated serum cholesterol levels to activation of innate immunity signaling pathways. Nat Med. 2004;10:416-421. (Pubitemid 38508522)
-
(2004)
Nature Medicine
, vol.10
, Issue.4
, pp. 416-421
-
-
Bjorkbacka, H.1
Kunjathoor, V.V.2
Moore, K.J.3
Koehn, S.4
Ordija, C.M.5
Lee, M.A.6
Means, T.7
Halmen, K.8
Luster, A.D.9
Golenbock, D.T.10
Freeman, M.W.11
-
13
-
-
0025970427
-
Endotoxemia in human septic shock
-
Danner RL, Elin RJ, Hosseini JM, Wesley RA, Reilly JM, Parillo JE. Endotoxemia in human septic shock. Chest. 1991;99:169-175.
-
(1991)
Chest
, vol.99
, pp. 169-175
-
-
Danner, R.L.1
Elin, R.J.2
Hosseini, J.M.3
Wesley, R.A.4
Reilly, J.M.5
Parillo, J.E.6
-
14
-
-
10844295809
-
TLR activation synergizes with Kilham rat virus infection to induce diabetes in BBDR rats
-
Zipris D, Lien E, Xie JX, Greiner DL, Mordes JP, Rossini AA. TLR activation synergizes with Kilham rat virus infection to induce diabetes in BBDR rats. J Immunol. 2005;174:131-142. (Pubitemid 40007399)
-
(2005)
Journal of Immunology
, vol.174
, Issue.1
, pp. 131-142
-
-
Zipris, D.1
Lien, E.2
Xie, J.X.3
Greiner, D.L.4
Mordes, J.P.5
Rossini, A.A.6
-
15
-
-
0142166328
-
Cancer chemoprevention with dietary phytochemicals
-
Surh YJ. Cancer chemoprevention with dietary phytochemicals. Nat Rev Cancer. 2003;3:768-780.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 768-780
-
-
Surh, Y.J.1
-
16
-
-
33751011612
-
Auranofin, as an anti-rheumatic gold compound, suppresses LPS-induced homodimerization of TLR4
-
DOI 10.1016/j.bbrc.2006.09.097, PII S0006291X06021462
-
Youn HS, Lee JY, Saitoh SI, Miyake K, Hwang DH. Auranofin, as an anti-rheumatic gold compound, suppresses LPS-induced homodimerization of TLR4. Biochem Biophys Res Commun. 2006;350:866-871. (Pubitemid 44739925)
-
(2006)
Biochemical and Biophysical Research Communications
, vol.350
, Issue.4
, pp. 866-871
-
-
Youn, H.S.1
Lee, J.Y.2
Saitoh, S.I.3
Miyake, K.4
Hwang, D.H.5
-
17
-
-
55549114046
-
Low density lipoprotein (LDL)-antioxidant flavonoids from roots of Sophora flavescens
-
Jeong TS, Ryu YB, Kim HY, Curtis-Long MJ, An SJ, Lee JH, et al. Low density lipoprotein (LDL)-antioxidant flavonoids from roots of Sophora flavescens. Biol Pharm Bull. 2008;31:2097-2102.
-
(2008)
Biol Pharm Bull
, vol.31
, pp. 2097-2102
-
-
Jeong, T.S.1
Ryu, Y.B.2
Kim, H.Y.3
Curtis-Long, M.J.4
An, S.J.5
Lee, J.H.6
-
18
-
-
32044439599
-
Glycosidase inhibitory flavonoids from Sophora flavescens
-
DOI 10.1109/TCOMM.2005.863731
-
Kim JH, Ryu YB, Kang NS, Lee BW, Heo JS, Jeong IY, et al. Glycosidase inhibitory flavonoids from Sophora flavescens. Biol Pharm Bull. 2006;29:302-305. (Pubitemid 43200901)
-
(2006)
Biological and Pharmaceutical Bulletin
, vol.29
, Issue.2
, pp. 302-305
-
-
Kim, J.H.1
Ryu, Y.B.2
Kang, N.S.3
Lee, B.W.4
Heo, J.S.5
Jeong, I.-Y.6
Park, K.H.7
-
19
-
-
0033451463
-
Antibacterial and antiandrogen flavonoids from Sophora flavescens
-
DOI 10.1021/np990051d
-
Kuroyanagi M, Arakawa T, Hirayama Y, Hayashi T. Antibacterial and antiandrogen flavonoids from Sophora flavescens. J Nat Prod. 1999;62:1595-1599. (Pubitemid 30030595)
-
(1999)
Journal of Natural Products
, vol.62
, Issue.12
, pp. 1595-1599
-
-
Kuroyanagi, M.1
Arakawa, T.2
Hirayama, Y.3
Hayashi, T.4
-
20
-
-
55749115412
-
Pterocarpans and flavanones from Sophora flavescens displaying potent neuraminidase inhibition
-
Ryu YB, Curtis-Long MJ, Kim JH, Jeong SH, Yang MS, Lee KW, et al. Pterocarpans and flavanones from Sophora flavescens displaying potent neuraminidase inhibition. Bioorg Med Chem Lett. 2008;18:6046-6049.
-
(2008)
Bioorg Med Chem Lett
, vol.18
, pp. 6046-6049
-
-
Ryu, Y.B.1
Curtis-Long, M.J.2
Kim, J.H.3
Jeong, S.H.4
Yang, M.S.5
Lee, K.W.6
-
21
-
-
0037826011
-
Prenylated flavonoids from the roots of Sophora flavescens with tyrosinase inhibitory activity
-
DOI 10.1055/s-2003-40643
-
Son JK, Park JS, Kim JA, Kim Y, Chung SR, Lee SH. Prenylated flavonoids from the roots of Sophora flavescens with tyrosinase inhibitory activity. Planta Med. 2003;69:559-561. (Pubitemid 36870635)
-
(2003)
Planta Medica
, vol.69
, Issue.6
, pp. 559-561
-
-
Son, J.K.1
Park, J.S.2
Kim, J.A.3
Kim, Y.4
Chung, S.R.5
Lee, S.H.6
-
22
-
-
0030939013
-
Potent inhibition of respiratory syncytial virus by polyoxometalates of several structural classes
-
DOI 10.1016/S0166-3542(96)01019-4, PII S0166354296010194
-
Barnard DL, Hill CL, Gage T, Matheson JE, Huffman JH, Sidwell RW, et al. Potent inhibition of respiratory syncytial virus by polyoxometalates of several structural classes. Antiviral Res. 1997;34:27-37. (Pubitemid 27132855)
-
(1997)
Antiviral Research
, vol.34
, Issue.1
, pp. 27-37
-
-
Barnard, D.L.1
Hill, C.L.2
Gage, T.3
Matheson, J.E.4
Huffman, J.H.5
Sidwell, R.W.6
Otto, M.I.7
Schinazi, R.F.8
-
23
-
-
0035710746
-
-DeltaDeltaCT method
-
DOI 10.1006/meth.2001.1262
-
Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods. 2001;25:402-408. (Pubitemid 34164012)
-
(2001)
Methods
, vol.25
, Issue.4
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
24
-
-
0038714270
-
Poly(dI-dC)-induced Toll-like receptor 3 (TLR3)-mediated activation of NFkappaB and MAP kinase is through an interleukin-1 receptor-associated kinase (IRAK)-independent pathway employing the signaling components TLR3-TRAF6-TAK1-TAB2-PKR
-
DOI 10.1074/jbc.M300562200
-
Jiang Z, Zamanian-Daryoush M, Nie H, Silva AM, Williams BR, Li X. Poly(I-C)-induced Toll-like receptor 3 (TLR3)-mediated activation of NFkappa B and MAP kinase is through an interleukin- 1 receptor-associated kinase (IRAK)-independent pathway employing the signaling components TLR3-TRAF6-TAK1-TAB2-PKR. J Biol Chem. 2003;278:16713-16719. (Pubitemid 36799536)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.19
, pp. 16713-16719
-
-
Jiang, Z.1
Zamanian-Daryoush, M.2
Nie, H.3
Silva, A.M.4
Williams, B.R.G.5
Li, X.6
-
26
-
-
0344825775
-
Cytokines as Mediators for or Effectors against Rotavirus Disease in Children
-
DOI 10.1128/CDLI.10.6.995-1001.2003
-
Jiang B, Snipes-Magaldi L, Dennehy P, Keyserling H, Holman RC, Bresee J, et al. Cytokines as mediators for or effectors against rotavirus disease in children. Clin Diagn Lab Immunol. 2003;10:995-1001. (Pubitemid 37444264)
-
(2003)
Clinical and Diagnostic Laboratory Immunology
, vol.10
, Issue.6
, pp. 995-1001
-
-
Jiang, B.1
Snipes-Magaldi, L.2
Dennehy, P.3
Keyserling, H.4
Holman, R.C.5
Bresee, J.6
Gentsch, J.7
Glass, R.I.8
-
28
-
-
0041331693
-
Subcellular localization of toll-like receptor 3 in human dendritic cells
-
Matsumoto M, Funami K, Tanabe M, Oshiumi H, Shingai M, Seto Y, et al. Subcellular localization of Toll-like receptor 3 in human dendritic cells. J Immunol. 2003;171:3154-3162. (Pubitemid 37093540)
-
(2003)
Journal of Immunology
, vol.171
, Issue.6
, pp. 3154-3162
-
-
Matsumoto, M.1
Funami, K.2
Tanabe, M.3
Oshiumi, H.4
Shingai, M.5
Seto, Y.6
Yamamoto, A.7
Seya, T.8
-
29
-
-
4544264420
-
Pathogenesis of intestinal and systemic rotavirus infection
-
DOI 10.1128/JVI.78.19.10213-10220.2004
-
Ramig RF. Pathogenesis of intestinal and systemic rotavirus infection. J Virol. 2004;78:10213-10220. (Pubitemid 39258345)
-
(2004)
Journal of Virology
, vol.78
, Issue.19
, pp. 10213-10220
-
-
Ramig, R.F.1
-
30
-
-
1542317550
-
Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA
-
Diebold SS, Kaisho T, Hemmi H, Akira S, Reis e Sousa C. Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA. Science. 2004;303:1529-1531.
-
(2004)
Science
, vol.303
, pp. 1529-1531
-
-
Diebold, S.S.1
Kaisho, T.2
Hemmi, H.3
Akira, S.4
Reis E Sousa, C.5
-
31
-
-
1542317578
-
Species-Specific Recognition of Single-Stranded RNA via Till-like Receptor 7 and 8
-
DOI 10.1126/science.1093620
-
Heil F, Hemmi H, Hochrein H, Ampenberger F, Kirschning C, Akira S, et al. Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8. Science. 2004;303:1526-1529. (Pubitemid 38314424)
-
(2004)
Science
, vol.303
, Issue.5663
, pp. 1526-1529
-
-
Heil, F.1
Hemmi, H.2
Hochrein, H.3
Ampenberger, F.4
Kirschning, C.5
Akira, S.6
Lipford, G.7
Wagner, H.8
Bauer, S.9
-
32
-
-
1842631428
-
Recognition of single-stranded RNA viruses by Toll-like receptor 7
-
DOI 10.1073/pnas.0400937101
-
Lund JM, Alexopoulou L, Sato A, Karow M, Adams NC, Gale NW, et al. Recognition of single-stranded RNA viruses by Toll-like receptor 7. Proc Natl Acad Sci U S A. 2004;101:5598-5603. (Pubitemid 38481202)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.15
, pp. 5598-5603
-
-
Lund, J.M.1
Alexopoulou, L.2
Sato, A.3
Karow, M.4
Adams, N.C.5
Gale, N.W.6
Iwasaki, A.7
Flavell, R.A.8
-
33
-
-
69949090343
-
Impact of matrine on inflammation related factors in rat intestinal microvascular endothelial cells
-
Suo Z, Liu Y, Ferreri M, Zhang T, Liu Z, Mu X, et al. Impact of matrine on inflammation related factors in rat intestinal microvascular endothelial cells. J Ethnopharmacol. 2009;125:404-409.
-
(2009)
J Ethnopharmacol
, vol.125
, pp. 404-409
-
-
Suo, Z.1
Liu, Y.2
Ferreri, M.3
Zhang, T.4
Liu, Z.5
Mu, X.6
-
34
-
-
70349741080
-
Baculovirus transduction of mesenchymal stem cells triggers the toll-like receptor 3 pathway
-
Chen GY, Shiah HC, Su HJ, Chen CY, Chuang YJ, Lo WH, et al. Baculovirus transduction of mesenchymal stem cells triggers the toll-like receptor 3 pathway. J Virol. 2009;83:10548-10556.
-
(2009)
J Virol
, vol.83
, pp. 10548-10556
-
-
Chen, G.Y.1
Shiah, H.C.2
Su, H.J.3
Chen, C.Y.4
Chuang, Y.J.5
Lo, W.H.6
-
35
-
-
77953306075
-
Rotavirus nonstructural protein 1 suppresses virus-induced cellular apoptosis to facilitate viral growth by activating the cell survival pathways during early stages of infection
-
Bagchi P, Dutta D, Chattopadhyay S, Mukherjee A, Halder UC, Sarkar S, et al. Rotavirus nonstructural protein 1 suppresses virus-induced cellular apoptosis to facilitate viral growth by activating the cell survival pathways during early stages of infection. J Virol. 2010;84:6834-6845.
-
(2010)
J Virol
, vol.84
, pp. 6834-6845
-
-
Bagchi, P.1
Dutta, D.2
Chattopadhyay, S.3
Mukherjee, A.4
Halder, U.C.5
Sarkar, S.6
-
36
-
-
20444442721
-
Distinct poly(I-C) and virus-activated signaling pathways leading to interferon-beta production in hepatocytes
-
DOI 10.1074/jbc.M414139200
-
Li K, Chen Z, Kato N, Gale M Jr, Lemon SM. Distinct poly(I-C) and virus-activated signaling pathways leading to interferon-beta production in hepatocytes. J Biol Chem. 2005;280:16739-16747. (Pubitemid 41389131)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.17
, pp. 16739-16747
-
-
Li, K.1
Chen, Z.2
Kato, N.3
Gale Jr., M.4
Lemon, S.M.5
-
37
-
-
2442512030
-
The antiviral effect of interferon-beta against SARS-Coronavirus is not mediated by MxA protein
-
DOI 10.1016/j.jcv.2003.11.013, PII S1386653203003251
-
Spiegel M, Pichlmair A, Muhlberger E, Haller O, Weber F. The antiviral effect of interferon-beta against SARS-coronavirus is not mediated by MxA protein. J Clin Virol. 2004;30:211-213. (Pubitemid 38622001)
-
(2004)
Journal of Clinical Virology
, vol.30
, Issue.3
, pp. 211-213
-
-
Spiegel, M.1
Pichlmair, A.2
Muhlberger, E.3
Haller, O.4
Weber, F.5
-
38
-
-
27944449008
-
IFN-beta in rheumatoid arthritis
-
Tak PP. IFN-beta in rheumatoid arthritis. Front Biosci. 2004; 9:3242-3247.
-
(2004)
Front Biosci
, vol.9
, pp. 3242-3247
-
-
Tak, P.P.1
|