-
1
-
-
0035941407
-
The complete gene sequence of titin, expression of an unusual approximately 700-kDa titin isoform, and its interaction with obscurin identify a novel Z-line to I-band linking system
-
Bang ML, Centner T, Fornoff F, Geach AJ, Gotthardt M, McNabb M, Witt CC, Labeit D, Gregorio CC, Granzier H, Labeit S,. 2001. The complete gene sequence of titin, expression of an unusual approximately 700-kDa titin isoform, and its interaction with obscurin identify a novel Z-line to I-band linking system. Circ Res 89: 1065-1072.
-
(2001)
Circ Res
, vol.89
, pp. 1065-1072
-
-
Bang, M.L.1
Centner, T.2
Fornoff, F.3
Geach, A.J.4
Gotthardt, M.5
McNabb, M.6
Witt, C.C.7
Labeit, D.8
Gregorio, C.C.9
Granzier, H.10
Labeit, S.11
-
2
-
-
0028895417
-
Exon recognition in vertebrate splicing
-
Berget SM,. 1995. Exon recognition in vertebrate splicing. J Biol Chem 270: 2411-2414.
-
(1995)
J Biol Chem
, vol.270
, pp. 2411-2414
-
-
Berget, S.M.1
-
3
-
-
0035793703
-
Identification of muscle specific ring finger proteins as potential regulators of the titin kinase domain
-
Centner T, Yano J, Kimura E, McElhinny AS, Pelin K, Witt CC, Bang ML, Trombitas K, Granzier H, Gregorio CC, Sorimachi H, Labeit S,. 2001. Identification of muscle specific ring finger proteins as potential regulators of the titin kinase domain. J Mol Biol 306: 717-726.
-
(2001)
J Mol Biol
, vol.306
, pp. 717-726
-
-
Centner, T.1
Yano, J.2
Kimura, E.3
McElhinny, A.S.4
Pelin, K.5
Witt, C.C.6
Bang, M.L.7
Trombitas, K.8
Granzier, H.9
Gregorio, C.C.10
Sorimachi, H.11
Labeit, S.12
-
4
-
-
18544406997
-
Series of exon-skipping events in the elastic spring region of titin as the structural basis for myofibrillar elastic diversity
-
Freiburg A, Trombitas K, Hell W, Cazorla O, Fougerousse F, Centner T, Kolmerer B, Witt C, Beckmann JS, Gregorio CC, Granzier H, Labeit S,. 2000. Series of exon-skipping events in the elastic spring region of titin as the structural basis for myofibrillar elastic diversity. Circ Res 86: 1114-1121.
-
(2000)
Circ Res
, vol.86
, pp. 1114-1121
-
-
Freiburg, A.1
Trombitas, K.2
Hell, W.3
Cazorla, O.4
Fougerousse, F.5
Centner, T.6
Kolmerer, B.7
Witt, C.8
Beckmann, J.S.9
Gregorio, C.C.10
Granzier, H.11
Labeit, S.12
-
5
-
-
0025062549
-
Elastic filaments in skeletal muscle revealed by selective removal of thin filaments with plasma gelsolin
-
Funatsu T, Higuchi H, Ishiwata S,. 1990. Elastic filaments in skeletal muscle revealed by selective removal of thin filaments with plasma gelsolin. J Cell Biol 110: 53-62.
-
(1990)
J Cell Biol
, vol.110
, pp. 53-62
-
-
Funatsu, T.1
Higuchi, H.2
Ishiwata, S.3
-
6
-
-
0023924769
-
The organization of titin filaments in the half-sarcomere revealed by monoclonal antibodies in immunoelectron microscopy: A map of ten nonrepetitive epitopes starting at the Z line extends close to the M line
-
Fürst DO, Osborn M, Nave R, Weber K,. 1988. The organization of titin filaments in the half-sarcomere revealed by monoclonal antibodies in immunoelectron microscopy: A map of ten nonrepetitive epitopes starting at the Z line extends close to the M line. J Cell Biol 106: 1563-1572.
-
(1988)
J Cell Biol
, vol.106
, pp. 1563-1572
-
-
Fürst, D.O.1
Osborn, M.2
Nave, R.3
Weber, K.4
-
7
-
-
0028957373
-
Passive tension in cardiac muscle: Contribution of collagen, titin, microtubules, and intermediate filaments
-
Granzier HL, Irving TC,. 1995. Passive tension in cardiac muscle: Contribution of collagen, titin, microtubules, and intermediate filaments. Biophys J 68: 1027-1044.
-
(1995)
Biophys J
, vol.68
, pp. 1027-1044
-
-
Granzier, H.L.1
Irving, T.C.2
-
8
-
-
0037907752
-
Species variations in cDNA sequence and exon splicing patterns in the extensible I-band region of cardiac titin: Relation to passive tension
-
Greaser ML, Berri M, Warren CM, Mozdziak PE,. 2002. Species variations in cDNA sequence and exon splicing patterns in the extensible I-band region of cardiac titin: Relation to passive tension. J Muscle Res Cell Motil 23: 473-482.
-
(2002)
J Muscle Res Cell Motil
, vol.23
, pp. 473-482
-
-
Greaser, M.L.1
Berri, M.2
Warren, C.M.3
Mozdziak, P.E.4
-
9
-
-
33745698386
-
Developmental changes in rat cardiac titin/connectin: Transitions in normal animals and in mutants with a delayed pattern of isoform transition
-
Greaser ML, Krzesinski PR, Warren CM, Kirkpatrick B, Campbell KS, Moss RL,. 2005. Developmental changes in rat cardiac titin/connectin: Transitions in normal animals and in mutants with a delayed pattern of isoform transition. J Muscle Res Cell Motil 26: 325-332.
-
(2005)
J Muscle Res Cell Motil
, vol.26
, pp. 325-332
-
-
Greaser, M.L.1
Krzesinski, P.R.2
Warren, C.M.3
Kirkpatrick, B.4
Campbell, K.S.5
Moss, R.L.6
-
10
-
-
44649200448
-
Mutation that dramatically alters rat titin isoform expression and cardiomyocyte passive tension
-
Greaser ML, Warren CM, Esbona K, Guo W, Duan Y, Parrish AM, Krzesinski PR, Norman HS, Dunning S, Fitzsimons DP, Moss RL,. 2008. Mutation that dramatically alters rat titin isoform expression and cardiomyocyte passive tension. J Mol Cell Cardiol 44: 983-991.
-
(2008)
J Mol Cell Cardiol
, vol.44
, pp. 983-991
-
-
Greaser, M.L.1
Warren, C.M.2
Esbona, K.3
Guo, W.4
Duan, Y.5
Parrish, A.M.6
Krzesinski, P.R.7
Norman, H.S.8
Dunning, S.9
Fitzsimons, D.P.10
Moss, R.L.11
-
11
-
-
0032538660
-
2 terminus of titin spans the Z-disc: Its interaction with a novel 19-kD ligand (T-cap) is required for sarcomeric integrity
-
2 terminus of titin spans the Z-disc: Its interaction with a novel 19-kD ligand (T-cap) is required for sarcomeric integrity. J Cell Biol 143: 1013-1027.
-
(1998)
J Cell Biol
, vol.143
, pp. 1013-1027
-
-
Gregorio, C.C.1
Trombitás, K.2
Centner, T.3
Kolmerer, B.4
Stier, G.5
Kunke, K.6
Suzuki, K.7
Obermayr, F.8
Herrmann, B.9
Granzier, H.10
Sorimachi, H.11
Labeit, S.12
-
12
-
-
0033546073
-
Mechanically driven contour-length adjustment in rat cardiac titin's unique N2B sequence: Titin is an adjustable spring
-
Helmes M, Trombitás K, Centner T, Kellermayer M, Labeit S, Linke WA, Granzier H,. 1999. Mechanically driven contour-length adjustment in rat cardiac titin's unique N2B sequence: Titin is an adjustable spring. Circ Res 84: 1339-1352.
-
(1999)
Circ Res
, vol.84
, pp. 1339-1352
-
-
Helmes, M.1
Trombitás, K.2
Centner, T.3
Kellermayer, M.4
Labeit, S.5
Linke, W.A.6
Granzier, H.7
-
13
-
-
0023576830
-
The positional stability of thick filaments in activated skeletal muscle depends on sarcomere length: Evidence for the role of titin filaments
-
Horowits R, Podolsky RJ,. 1987. The positional stability of thick filaments in activated skeletal muscle depends on sarcomere length: Evidence for the role of titin filaments. J Cell Biol 105: 2217-2223.
-
(1987)
J Cell Biol
, vol.105
, pp. 2217-2223
-
-
Horowits, R.1
Podolsky, R.J.2
-
14
-
-
0026582867
-
Towards a molecular understanding of titin
-
Labeit S, Gautel M, Lakey A, Trinick J,. 1992. Towards a molecular understanding of titin. EMBO J 11: 1711-1716.
-
(1992)
EMBO J
, vol.11
, pp. 1711-1716
-
-
Labeit, S.1
Gautel, M.2
Lakey, A.3
Trinick, J.4
-
15
-
-
0028824480
-
Titins: Giant proteins in charge of muscle ultrastructure and elasticity
-
Labeit S, Kolmerer B,. 1995. Titins: Giant proteins in charge of muscle ultrastructure and elasticity. Science 270: 293-296.
-
(1995)
Science
, vol.270
, pp. 293-296
-
-
Labeit, S.1
Kolmerer, B.2
-
16
-
-
1242281665
-
Developmental control of titin isoform expression and passive stiffness in fetal and neonatal myocardium
-
Lahmers S, Wu Y, Call DR, Labeit S, Granzier H,. 2004. Developmental control of titin isoform expression and passive stiffness in fetal and neonatal myocardium. Circ Res 94: 505-513.
-
(2004)
Circ Res
, vol.94
, pp. 505-513
-
-
Lahmers, S.1
Wu, Y.2
Call, D.R.3
Labeit, S.4
Granzier, H.5
-
17
-
-
0033538859
-
I-band titin in cardiac muscle is a three-element molecular spring and is critical for maintaining thin filament structure
-
Linke WA, Rudy DE, Centner T, Gautel M, Witt C, Labeit S, Gregorio CC,. 1999. I-band titin in cardiac muscle is a three-element molecular spring and is critical for maintaining thin filament structure. J Cell Biol 146: 631-644.
-
(1999)
J Cell Biol
, vol.146
, pp. 631-644
-
-
Linke, W.A.1
Rudy, D.E.2
Centner, T.3
Gautel, M.4
Witt, C.5
Labeit, S.6
Gregorio, C.C.7
-
18
-
-
0017163222
-
Connectin, an elastic protein from myofibrils
-
Maruyama K,. 1976. Connectin, an elastic protein from myofibrils. J Biochem 80: 405-407.
-
(1976)
J Biochem
, vol.80
, pp. 405-407
-
-
Maruyama, K.1
-
19
-
-
0021279759
-
Molecular size and shape of beta-connectin, an elastic protein of striated muscle
-
Maruyama K, Kimura S, Yoshidomi H, Sawada H, Kikuchi M,. 1984. Molecular size and shape of beta-connectin, an elastic protein of striated muscle. J Biochem 95: 1423-1433.
-
(1984)
J Biochem
, vol.95
, pp. 1423-1433
-
-
Maruyama, K.1
Kimura, S.2
Yoshidomi, H.3
Sawada, H.4
Kikuchi, M.5
-
20
-
-
0036544533
-
Muscle-specific RING finger-1 interacts with titin to regulate sarcomeric M-line and thick filament structure and may have nuclear functions via its interaction with glucocorticoid modulatory element binding protein-1
-
McElhinny AS, Kakinuma K, Sorimachi H, Labeit S, Gregorio CC,. 2002. Muscle-specific RING finger-1 interacts with titin to regulate sarcomeric M-line and thick filament structure and may have nuclear functions via its interaction with glucocorticoid modulatory element binding protein-1. J Cell Biol 157: 125-136.
-
(2002)
J Cell Biol
, vol.157
, pp. 125-136
-
-
McElhinny, A.S.1
Kakinuma, K.2
Sorimachi, H.3
Labeit, S.4
Gregorio, C.C.5
-
21
-
-
0036779359
-
Titin-cap associates with, and regulates secretion of myostatin
-
Nicholas G, Thomas M, Langley B, Somers W, Patel K, Kemp CF, Sharma M, Kambadur R,. 2002. Titin-cap associates with, and regulates secretion of myostatin. J Cell Physiol 193: 120-131.
-
(2002)
J Cell Physiol
, vol.193
, pp. 120-131
-
-
Nicholas, G.1
Thomas, M.2
Langley, B.3
Somers, W.4
Patel, K.5
Kemp, C.F.6
Sharma, M.7
Kambadur, R.8
-
22
-
-
0031034775
-
Molecular structure of the sarcomeric M band: Mapping of titin and myosin binding domains in myomesin and the identification of a potential regulatory phosphorylation site in myomesin
-
Obermann WM, Gautel M, Weber K, Fürst DO,. 1997. Molecular structure of the sarcomeric M band: Mapping of titin and myosin binding domains in myomesin and the identification of a potential regulatory phosphorylation site in myomesin. EMBO J 16: 211-220.
-
(1997)
EMBO J
, vol.16
, pp. 211-220
-
-
Obermann, W.M.1
Gautel, M.2
Weber, K.3
Fürst, D.O.4
-
23
-
-
0031560933
-
The N-terminal Z repeat 5 of connectin/titin binds to the C-terminal region of alpha-actinin
-
Ohtsuka H, Yajima H, Maruyama K, Kimura S,. 1997. The N-terminal Z repeat 5 of connectin/titin binds to the C-terminal region of alpha-actinin. Biochem Biophys Res Commun 235: 1-3.
-
(1997)
Biochem Biophys Res Commun
, vol.235
, pp. 1-3
-
-
Ohtsuka, H.1
Yajima, H.2
Maruyama, K.3
Kimura, S.4
-
24
-
-
1842830381
-
Developmentally regulated switching of titin size alters myofibrillar stiffness in the perinatal heart
-
Opitz CA, Leake MC, Makarenko I, Benes V, Linke WA,. 2004. Developmentally regulated switching of titin size alters myofibrillar stiffness in the perinatal heart. Circ Res 16 (94): 967-975.
-
(2004)
Circ Res
, vol.16
, Issue.94
, pp. 967-975
-
-
Opitz, C.A.1
Leake, M.C.2
Makarenko, I.3
Benes, V.4
Linke, W.A.5
-
25
-
-
70449124198
-
Tuning passive mechanics through differential splicing of titin during skeletal muscle development
-
Ottenheijm CA, Knottnerus AM, Buck D, Luo X, Greer K, Hoying A, Labeit S, Granzier H,. 2009. Tuning passive mechanics through differential splicing of titin during skeletal muscle development. Biophys J 97: 2277-2286.
-
(2009)
Biophys J
, vol.97
, pp. 2277-2286
-
-
Ottenheijm, C.A.1
Knottnerus, A.M.2
Buck, D.3
Luo, X.4
Greer, K.5
Hoying, A.6
Labeit, S.7
Granzier, H.8
-
26
-
-
27644545054
-
Isoform diversity of giant proteins in relation to passive and active contractile properties of rabbit skeletal muscles
-
Prado LG, Makarenko I, Andresen C, Krüger M, Opitz CA, Linke WA,. 2005. Isoform diversity of giant proteins in relation to passive and active contractile properties of rabbit skeletal muscles. J Gen Physiol 126: 461-480.
-
(2005)
J Gen Physiol
, vol.126
, pp. 461-480
-
-
Prado, L.G.1
Makarenko, I.2
Andresen, C.3
Krüger, M.4
Opitz, C.A.5
Linke, W.A.6
-
27
-
-
12244291970
-
Transient association of titin and myosin with microtubules in nascent myofibrils directed by the MURF2 RING-finger protein
-
Pizon V, Iakovenko A, Van Der Ven PF, Kelly R, Fatu C, Fürst DO, Karsenti E, Gautel M,. 2002. Transient association of titin and myosin with microtubules in nascent myofibrils directed by the MURF2 RING-finger protein. J Cell Sci 115: 4469-4482.
-
(2002)
J Cell Sci
, vol.115
, pp. 4469-4482
-
-
Pizon, V.1
Iakovenko, A.2
Van Der Ven, P.F.3
Kelly, R.4
Fatu, C.5
Fürst, D.O.6
Karsenti, E.7
Gautel, M.8
-
28
-
-
0031213849
-
Tissue-specific expression and alpha-actinin binding properties of the Z-disc titin: Implications for the nature of vertebrate Z-discs
-
Sorimachi H, Freiburg A, Kolmerer B, Ishiura S, Stier G, Gregorio CC, Labeit D, Linke WA, Suzuki K, Labeit S,. 1997. Tissue-specific expression and alpha-actinin binding properties of the Z-disc titin: Implications for the nature of vertebrate Z-discs. J Mol Biol 270: 688-695.
-
(1997)
J Mol Biol
, vol.270
, pp. 688-695
-
-
Sorimachi, H.1
Freiburg, A.2
Kolmerer, B.3
Ishiura, S.4
Stier, G.5
Gregorio, C.C.6
Labeit, D.7
Linke, W.A.8
Suzuki, K.9
Labeit, S.10
-
29
-
-
0021591504
-
Purification and properties of native titin
-
Trinick J, Knight P, Whiting A,. 1984. Purification and properties of native titin. J Mol Biol 180: 331-356.
-
(1984)
J Mol Biol
, vol.180
, pp. 331-356
-
-
Trinick, J.1
Knight, P.2
Whiting, A.3
-
30
-
-
0032785903
-
Molecular dissection of N2B cardiac titin's extensibility
-
Trombitás K, Freiburg A, Centner T, Labeit S, Granzier H,. 1999. Molecular dissection of N2B cardiac titin's extensibility. Biophys J 77: 3189-3196.
-
(1999)
Biophys J
, vol.77
, pp. 3189-3196
-
-
Trombitás, K.1
Freiburg, A.2
Centner, T.3
Labeit, S.4
Granzier, H.5
-
32
-
-
0011450535
-
Titin: Major myofibrillar components of striated muscle
-
Wang K, McClure J, Tu A,. 1979. Titin: Major myofibrillar components of striated muscle. Proc Natl Acad Sci USA 76: 3698-3702.
-
(1979)
Proc Natl Acad Sci USA
, vol.76
, pp. 3698-3702
-
-
Wang, K.1
McClure, J.2
Tu, A.3
-
33
-
-
0021452202
-
Titin is an extraordinarily long, flexible, and slender myofibrillar protein
-
Wang K, Ramirez-Mitchell R, Palter D,. 1984. Titin is an extraordinarily long, flexible, and slender myofibrillar protein. Proc Natl Acad Sci USA 81: 3685-3689.
-
(1984)
Proc Natl Acad Sci USA
, vol.81
, pp. 3685-3689
-
-
Wang, K.1
Ramirez-Mitchell, R.2
Palter, D.3
-
34
-
-
0025816649
-
Regulation of skeletal muscle stiffness and elasticity by titin isoforms: A test of the segmental extension model of resting tension
-
Wang K, McCarter R, Wright J, Beverly J, Ramirez-Mitchell R,. 1991. Regulation of skeletal muscle stiffness and elasticity by titin isoforms: A test of the segmental extension model of resting tension. Proc Natl Acad Sci USA 88: 7101-7105.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 7101-7105
-
-
Wang, K.1
McCarter, R.2
Wright, J.3
Beverly, J.4
Ramirez-Mitchell, R.5
-
35
-
-
0038219368
-
Vertical agarose gel electrophoresis and electroblotting of high-molecular-weight proteins
-
Warren CM, Krzesinski PR, Greaser ML,. 2003. Vertical agarose gel electrophoresis and electroblotting of high-molecular-weight proteins. Electrophoresis 24: 1695-1702.
-
(2003)
Electrophoresis
, vol.24
, pp. 1695-1702
-
-
Warren, C.M.1
Krzesinski, P.R.2
Greaser, M.L.3
-
36
-
-
5344277512
-
Titin isoform changes in rat myocardium during development
-
Warren CM, Krzesinski PR, Campbell KS, Moss RL, Greaser ML,. 2004. Titin isoform changes in rat myocardium during development. Mech Dev 121: 1301-1312.
-
(2004)
Mech Dev
, vol.121
, pp. 1301-1312
-
-
Warren, C.M.1
Krzesinski, P.R.2
Campbell, K.S.3
Moss, R.L.4
Greaser, M.L.5
-
37
-
-
0037192845
-
Molecular mechanics of cardiac titin's PEVK and N2B spring elements
-
Watanabe K, Nair P, Labeit D, Kellermayer MS, Greaser M, Labeit S, Granzier H,. 2002. Molecular mechanics of cardiac titin's PEVK and N2B spring elements. J Biol Chem 277: 11549-11558.
-
(2002)
J Biol Chem
, vol.277
, pp. 11549-11558
-
-
Watanabe, K.1
Nair, P.2
Labeit, D.3
Kellermayer, M.S.4
Greaser, M.5
Labeit, S.6
Granzier, H.7
-
38
-
-
0033576591
-
Both subunits of U2AF recognize the 3' splice site in Caenorhabditis elegans
-
Zorio DA, Blumenthal T,. 1999. Both subunits of U2AF recognize the 3' splice site in Caenorhabditis elegans. Nature 402: 835-838.
-
(1999)
Nature
, vol.402
, pp. 835-838
-
-
Zorio, D.A.1
Blumenthal, T.2
|