Monoallelic silencing and haploinsufficiency in early murine intestinal neoplasms

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 6, 2012, Pages 2060-2065

  Amos Landgraf, James M ^a   Irving, Amy A ^a,b   Hartman, Cory ^a   Hunter, Anthony ^a   Laube, Brianna ^a   Chen, Xiaodi ^a   Clipson, Linda ^a   Newton, Michael A ^c,d   Dove, William F ^a,b  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

^c University of Wisconsin Madison   (United States)

^d UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

Author keywords

Epigenetics; Genomic stability; Loss of imprinting; X inactivation

Indexed keywords

APC PROTEIN; BETA CATENIN; GENOMIC DNA; MESSENGER RNA; RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL NUCLEUS; CHROMOSOME 18; COLON POLYPOSIS; COLON TUMOR; CONTROLLED STUDY; CYTOPLASM; EPIGENETICS; GENE SEQUENCE; GENE SILENCING; GENETIC POLYMORPHISM; HAPLOINSUFFICIENCY; HETEROZYGOSITY; HETEROZYGOSITY LOSS; HISTOPATHOLOGY; INTESTINE TUMOR; MOUSE; NONHUMAN; NONSENSE MUTATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

ALLELES; ALTERNATIVE SPLICING; ANIMALS; BASE SEQUENCE; DNA, COMPLEMENTARY; EPIGENESIS, GENETIC; GENE DOSAGE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE SILENCING; GENES, APC; GENETIC LOCI; GENOME; HAPLOINSUFFICIENCY; HETEROZYGOTE; HUMANS; IMMUNOHISTOCHEMISTRY; INTESTINAL NEOPLASMS; MICE; MICE, INBRED C57BL; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; MUTATION; RATS; REPRODUCIBILITY OF RESULTS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

MURINAE; RATTUS;

EID: 84863116256     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1120753109     Document Type: Article

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