Structural basis for differential insertion kinetics of dNMPs opposite a difluorotoluene nucleotide residue

Biochemistry

Volumn 51, Issue 7, 2012, Pages 1476-1485

  Xia, Shuangluo ^a   Eom, Soo Hyun ^b   Konigsberg, William H ^a   Wang, Jimin ^a  

^a YALE UNIVERSITY   (United States)

^b Gwangju Institute of Science and Technology (GIST)   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE; BASE PAIRS; BASE SELECTIVITY; CHEMICAL FEATURES; DNA DUPLEXES; DNA POLYMERASE; ISOSTERIC; NON-POLAR; ORDERED WATER; STRUCTURAL BASIS; TEMPLATING; TERNARY COMPLEX; WILD TYPES;

HYDROGEN BONDS; NUCLEOTIDES;

KINETICS;

2,4 DIFLUOROTOLUENE; DNA POLYMERASE; HYDROGEN; NUCLEOTIDE; TOLUENE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CATALYSIS; CHEMICAL STRUCTURE; HYDROGEN BOND; KINETICS; PRIORITY JOURNAL;

CATALYSIS; CATALYTIC DOMAIN; CRYSTALLIZATION; DINUCLEOSIDE PHOSPHATES; DNA; DNA-DIRECTED DNA POLYMERASE; ESCHERICHIA COLI; HYDROGEN BONDING; KINETICS; MOLECULAR CONFORMATION; NUCLEOTIDES; TOLUENE; X-RAY DIFFRACTION;

EID: 84863115780     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi2016487     Document Type: Article

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