Activation of calpain, cathepsin-b and caspase-3 during transient focal cerebral ischemia in rat model

Neurochemical Research

Volumn 33, Issue 11, 2008, Pages 2178-2186

  Chaitanya, Ganta Vijay ^a   Babu, Phanithi Prakash ^a  

^a UNIVERSITY OF HYDERABAD   (India)

Author keywords

Active caspase 3; Apoptosis; Calpain; Cathepsin b; Focal cerebral ischemia; Middle cerebral artery occlusion; Necrosis; PSD 95; Spectrin

Indexed keywords

CALPAIN; CASPASE 3; CATHEPSIN B; POSTSYNAPTIC DENSITY PROTEIN 95; SPECTRIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN ISCHEMIA; CELL DEATH; CONTROLLED STUDY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NECROSIS; NONHUMAN; PRIORITY JOURNAL; RAT; REPERFUSION; WESTERN BLOTTING;

ANIMALS; BEHAVIOR, ANIMAL; BLOTTING, WESTERN; BRAIN ISCHEMIA; CALPAIN; CASPASE 3; CATHEPSIN B; ENZYME ACTIVATION; IMMUNOHISTOCHEMISTRY; MALE; RATS; RATS, WISTAR;

RATTUS; RATTUS NORVEGICUS;

EID: 52549100837     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11064-007-9567-7     Document Type: Article

References (25)

1. DJ Mc Conkey 1998 Biochemical determinants of apoptosis and necrosis Toxicol Lett 99 157 168
2. A Haunstetter S Izumo 1998 Apoptosis: basic mechanisms and implications for cardiovascular disease Circ Res 82 111 1129
3. P Syntichaki N Tavernarakis 2003 The biochemistry of neuronal necrosis: rogue biology? Nat Rev Neurosci 4 672 684
4. P Nicotera M Leist E Ferrando-may 1998 Intracellular ATP, a switch in the decision between apoptosis and necrosis. Toxicol lett 102-103 139 142
5. RM Sapolsky J Trafton GC Tombaugh 1996 Excitotoxic neuron death, acidotic endangerment, and the paradox of acidotic protection Adv Neurol 71 237 244
6. P Syntichaki C Samara N Tavernarakis 2005 The vacuolar H+ ATPase mediates intracellular acidification required for neurodegeneration in C. elegans Curr Biol 15 1249 1254
7. L Xiuli T van Vleet RG Schnellmann 2004 The role of Calpain in oncotic cell death Annu Rev Pharmacol Toxicol 44 349 70
8. A-S Marta C Samara P Syntichki N Tavernarakis 2006 Lysosomal biogenesis and function is critical for necrotic cell death in Caenorhabditis elegans The journal of Cell Biology 173 231 239
9. T Yamashima AB Tonchev T Tsukada TC Saido S Imajoh-Ohmi T Momoi E Kominami 2003 Sustained calpain activation is associated with lysosomal rupture executes necrosis of the post-ischemic CA1 neurons in primates Hippocampus 13 791 800
10. KK Wang 2000 Calpain and caspase: can you tell the difference? Trends Neurosci 23 20 26
11. K Lomgren C Zhu X Wang JO Karlsson AL Leverin BA Bahr C Mallard H Hagberg 2001 Synergistic activation of caspase-3 by m-calpain after neonatal hypoxia-ischemia: A mechanism of "pathologic apoptosis" J Biol Chem 276 10191 10198
12. M Kato T Nonaka M Maki H Kikuchi S Imajoh-Ohmi 2000 Caspases cleaves the amino-terminal calpain inhibitory unit of calpastatin during apoptosis in human jurkat T cells J Biochem 127 297 305
13. EZ Longa PR Weinstein S Carlson R Cummins 1989 Reversible middle cerebral artery occlusion without craniectomy in rats Stroke 20 84 91
14. L Zhang T Schallert ZG Zhang 2002 A test for detecting long-term sensorimotor dysfunction in the mouse after focal cerebral ischemia J Neurosci Meth 117 207 214
15. Cheng Du Rong Hu CA Csernansky CY Hsu DW Choi 1996 Very Delayed Infarction After Mild Focal Cerebral Ischemia: A Role for Apoptosis? Journal of Cerebral Blood Flow & Metabolism 16 195 201
16. S Lankiewicz LC Marc BN Truc AJ Krohn M Poppe GM Cole TC Saido JH Prehn 2000 Activation of calpain I converts excitotoxic neuron death into a caspase-independent cell death J Biol Chem 275 17064 17071
17. L Xiuli T van Vleet RG Schnellmann 2004 The role of Calpain in oncotic cell death Annu Rev Pharmacol Toxicol 44 349 70
18. JR Stefan Y Shi 2004 Molecular mechanisms of Caspases during apoptosis Nature Reviews Molecular Cell biology 5 897 907
19. C Charriaut-Marlangue I Margaill A Represa T Popovici M Plotkine Y Ben-Ari 1996 Apoptosis and necrosis after reversible focal ischemia: an in situ DNA fragmentation analysis J Cereb Blood Flow Metab 16 186 194
20. C Unal T Dalkara 2003 Intravenously administered propidium iodide labels necrotic cells in the intact mouse brain after injury Cell Death and Differentiation 10 928 929
21. I Unal-Çevik K Munire A Can Y Gürsoy-Özdemir T Dalkara 2004 Apoptotic and Necrotic death mechanisms are concomitantly activated in the same cell after Cerebral Ischemia Stroke 35 2189 2194
22. S Gobeil CC Boucher D Nadeau GG Poirier 2001 Characterization of the necrotic cleavage of poly (ADP-ribose) polymerase (PARP-1): implication of lysosomal proteases Cell Death Differ 8 588 94
23. YL Xiao Y Rong M Baudry 2000 Calpain-mediated degradation of PSD-95 in developing and adult rat brain Neuroscience Letters 286 149 153
24. T Yamashima 2000 Implication of cysteine proteases calpain, cathepsin and caspase in ischemic neuronal death of primates Prog Neurobiol 62 273 295
25. WN Robert A Xu H Gada RP Guttmann R Siman 2003 Cross talk between Calpain and Caspase proteolytic systems during neuronal apoptosis J Biol Chem 16 1462 1467