Engineering Yarrowia lipolytica to produce glycoproteins homogeneously modified with the universal man3GlcNAc2 N-glycan core

PLoS ONE

Volumn 7, Issue 6, 2012, Pages

  de Pourcq, Karen ^a,b   Tiels, Petra ^a,b   van Hecke, Annelies ^a,b   Geysens, Steven ^a,b,c   Vervecken, Wouter ^a,b,c   Callewaert, Nico ^a,b  

^a DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^b GHENT UNIVERSITY   (Belgium)

^c Oxyrane Belgium   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 1,3 GLUCOSYLTRANSFERASE; ALPHA 1,3 MANNOSYLTRANSFERASE; ALPHA MANNOSIDASE; GLUCOSE; GLUCOSIDASE; GLYCAN; GLYCOPROTEIN; MANNOSYLTRANSFERASE; MANNOTRIOSE N ACETYLGLUCOSAMINE; N ACETYLGLUCOSAMINE; UNCLASSIFIED DRUG;

ALG3 GENE; ALG6 GENE; ARTICLE; ASPERGILLUS NIGER; CARBOHYDRATE ANALYSIS; CARBOHYDRATE SYNTHESIS; ENZYME MODIFICATION; FUNGAL STRAIN; GENE; GENE DISRUPTION; GENE EXPRESSION SYSTEM; GENE OVEREXPRESSION; GENETIC ENGINEERING; GLYCOPROTEIN SYNTHESIS; GLYCOSYLATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN MODIFICATION; YARROWIA LIPOLYTICA;

ALPHA-GLUCOSIDASES; ANIMALS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENDOPLASMIC RETICULUM; GENE KNOCKOUT TECHNIQUES; GENES, FUNGAL; GENETIC ENGINEERING; GLUCOSE; GLYCOPROTEINS; GLYCOSYLATION; HUMANS; LIPASE; MANNOSIDASES; OLIGOSACCHARIDES; POLYSACCHARIDES; RATS; TRYPANOSOMA BRUCEI BRUCEI; YARROWIA;

YARROWIA LIPOLYTICA;

EID: 84863092388     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0039976     Document Type: Article

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