Cloning and characterization of the ALG3 gene of Saccharomyces cerevisiae

Glycobiology

Volumn 6, Issue 4, 1996, Pages 439-444

  Aebi, Markus ^a   Gassenhuber, Johann ^b   Domdey, Horst ^b   Te Heesen, Stephan ^a  

^a ETH ZURICH   (Switzerland)

^b UNIVERSITY OF MUNICH   (Germany)

Author keywords

Lipid linked oligosaccharide; N glycosylation; Synthetic lethality

Indexed keywords

MANNOSYLTRANSFERASE; OLIGOSACCHARIDE;

ARTICLE; GLYCOSYLATION; MOLECULAR CLONING; MUTANT; NONHUMAN; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE;

SACCHAROMYCES CEREVISIAE;

EID: 0029778262     PISSN: 09596658     EISSN: None     Source Type: Journal    
DOI: 10.1093/glycob/6.4.439     Document Type: Article

References (45)

1. Altschul, S.F., Gish, W., Miller, W., Myers, E.W. and Lipman, D.J. (1990) Basic local alignment search tool. J. Mol. Biol., 215, 403-410.
2. Camp, L.A., Chauhan, P., Farrar, J.D. and Lehrman, M.A. (1993) Defective rnannosylation of glycosylphosphatidylinositol in Lec35 Chinese hamster ovary cells. J. Biol. Chem., 268, 6721-6728.
3. Chapman, A., Li, E. and Kornfeld, S. (1979) The biosynthesis of the major lipid-linked oligosaccharide of Chinese hamster ovary cells occurs by the ordered addition of mannose residues. J. Biol. Chem., 254, 10243-10249.
4. Chapman, A., Fujimoto, K. and Kornfeld, S. (1980) The primary glycosylation defect in class E Thy-1-negative mutant mouse lymphoma cells is an inability to synthesize dolichol-P-mannose. J. Biol. Chem., 255, 4441-4446.
5. Conzelmann, A., Fankhauser, C., Puoti, A. and Desponds, C. (1991) Biosynthesis of glycophosphoinositol anchors in Saccharomyces cerevisiae. Cell Biol. Int. Rep., 15, 863-873.
6. Cusick, M.E (1994) Sequence of a segment of yeast chromosome II shows two novel genes, one almost entirely hydrophobic and the other extremely asparagine-serine rich. Yeast, 10, 1251-1256.
7. Fankhauser, C. and Conzelmann, A. (1991) Purification, biosynthesis and cellular localization of a major 125-kDa glycophosphatidylinositol anchored membrane glycoprotein. Eur. J Biochem., 195, 439-448.
8. Gaynor, E., te Heesen, S., Graham, T. R., Aebi, M. and Emr, S. (1994) Signal-mediated retrieval of a membrane protein from the golgi to the ER in yeast. J. Cell Biol., 127, 653-665.
9. Hamburger, D., Egerton, M. and Riezman, H. (1995) Yeast Gaa1p is required for attachment of a completed GPI anchor onto proteins. J. Cell Biol., 129, 629-639.
10. Hasilik, A. and Tanner, W. (1978) Carbohydrate moiety of carboxypeptidase Y and perturbation of its biosynthesis. Eur. J. Biochem., 91, 567-575.
11. Herscovics, A. and Orlean, P. (1993) Glycoprotein biosynthesis in yeast. FASEB J., 7, 540-550.
12. Hubbard, S.C. and Ivatt, R.J. (1981) Synthesis and processing of asparagine-linked oligosaccharides. Annu. Rev. Biochem., 50, 555-583.
13. Huffaker, T.C. and Robbins, P.W. (1981) Temperature-sensitive yeast mutants deficient in asparagine-linked glycosylation. J. Biol. Chem., 257, 3203-3210.
14. Huffaker, T.C. and Robbins, P.W. (1983) Yeast mutants deficient in protein glycosylation. Proc. Natl. Acad. Sci. USA, 80, 7466-7470.
15. Immervoll, T., Gentzsch, M. and Tanner, W. (1995) PMT3 and PMT4, two new members of the protein-O-mannosyltransferase gene family of Saccharomyces cerevisiae. Yeast, 11, 1345-1351.
16. Jackson, M.R., Nilsson, T. and Peterson, P.A. (1990) Identification of a consensus motif for retention of transmembrane proteins in the endoplasmic reticulum. EMBO J., 9, 3153-3162.
17. Kornfeld, R. and Kornfeld, S. (1985) Assembly of asparagine-linked oligosaccharides. Annu. Rev. Biochem., 54, 631-64.
18. Kurzik-Dumke, U. and Lohmann, E. (1995) Sequence of the new Drosophila melanogaster small heat-shock-related gene, lethal(2) essential for life [1(2)efl], at locus 59F4.5. Gene, 154, 171-175.
19. Kyte, J and Doolittle, R F (1982) A simple method for displaying the hydropathic character of a protein. J. Mol. Biol., 157, 105-132.
20. Lehrman, M.A. and Zeng, Y. (1989) Pleiotropic resistance to glycoprotein processing inhibitors in Chinese hamster ovary cells. The role of a novel mutation in the asparagine-linked glycosylation pathway. J. Biol. Chem., 264, 1584-93.
21. Obermaier, B., Gassenhuber, J., Piravandi, E. and Domdey, H. (1995) Sequence analysis of a 78.6 kb segment of the left end of Saccharomyces cerevisiae chromosome II. Yeast. 11, 1103-1112.
22. Orlean, P. (1990) Dolichol phosphate mannose synthase is required in vivo for glycosyl phosphatidylinositol membrane anchoring, O mannosylation, and N glycosylation of protein in Saccharomyces cerevisiae. Mol. Cell Biol., 10, 5796-5805.
23. Orlean, P. (1994). DPM1. In Rothblatt, J., Novick, P. and Stevens, T. (eds), Guidebook to the Secretory Pathway. Oxford University Press, Oxford, pp. 54-56.
24. Rosenwald, A.G. and Krag, S.S. (1990) Lec9 CHO glycosylation mutants are defective in the synthesis of dolichol. J Lipid Res. 31, 523-33.
25. Rosenwald, A.G., Stanley, P., McLachlan, K.R. and Krag, S.S. (1993) Mutants in dolichol synthesis: conversion of polyprenol to dolichol appears to be a rate-limiting step in dolichol synthesis. Glycobiology, 3, 481-8.
26. Rost, B., Casadio, R., Fariselli, P. and Sander, C. (1995) Transmembrane helices predicted at 95% accuracy. Protein Sci., 4, 521-533.
27. Runge, K.W. and Robbins, P.W. (1986) A new yeast mutation in the glucosylation steps of the asparagine-linked glycosylation pathway. J. Biol. Chem., 261, 15582-90.
28. Runge, K.W., Huffaker, T.C. and Robbins, P.W. (1984) Two yeast mutations in glucosylation steps of the asparagine glycosylation pathway. J. Biol. Chem., 259, 412-417.
29. Sathe, G.M., O'Brien, S, McLaughlin, M.M., Watson, F. and Livi, G.P (1991) Use of polymerase chain reaction for rapid detection of gene insertions in whole yeast cells. Nucleic Acids Res., 19, 4775
30. 2-PP-dolichol mannosyltransferase. Biochemistry, 29, 8901-8907.
31. Sherman, F. (1991). Getting started with yeast. In Guthrie, C. and Fink, G.R. (eds.), Guide to Yeast Genetics and Molecular Biology. Methods in Enzymology. Academic Press, San Diego, pp. 3-21.
32. Sherman, F. and Hicke, J. (1991). Micromanipulation and dissection of asci. In Guthrie, C. and Fink, G. (eds.), Guide to Yeast Genetics and Molecular Biology. Methods in Enzymology. Academic Press, San Diego, pp. 21-37.
33. Shin, J., Dunbrack, R.L., Lee, S. and Strominger, J.L. (1991) Signals for retention of transmembrane proteins in the endoplasmic reticulum studied with CD4 truncation mutants. Proc. Natl. Acad. Sci. USA, 88, 1918-1922.
34. Snider, M.D. and Rogers, O.C. (1984) Transmembrane movement of oligosaccharide-lipids during glycoprotein synthesis. Cell, 36, 753-761.
35. Stagljar, I., te Heesen, S. and Aebi, M. (1994) New phenotype of mutations deficient in the glycosylation of the lipid-linked oligosaccharide: the cloning of the ALG8 locus. Proc Natl. Acad. Sci. USA, 91, 5977-5981.
36. Staneloni, R.J., Ugalde, R.A. and Leloir, L.F. (1980) Addition of glucose to dolichyl diphosphate oligosaccharide and transfer to protein. Eur. J. Biochem., 105, 275-8.
37. Tanner, W. and Lehle, L. (1987) Protein glycosylation in yeast. Biochim. Biophys. Acta. 906, 81-99
38. te Heesen, S., Janetzky, B., Lehle, L. and Aebi, M. (1992) The yeast WBPI is essential for oligosaccharyltransferase activity in vivo and in vitro. EMBO J., 11, 2071-2075.
39. Verostek, M.F., Atkinson, P.H. and Trimble, R.B. (1991) Structure of Saccharomyces cerevisiae alg3,sec18 mutant oligosaccharides. J. Biol. Chem., 266, 5547-5551.
40. Verostek, M.F., Atkinson, P.H. and Trimble, R.B. (1993a) Glycoprotein biosynthesis in the alg3 Saccharomyces cerevisiae mutant. 1. Role of glucose in the initial glycosylation of invertase in the endoplasmic reticulum. J. Biol. Chem., 268, 12095-12103.
41. 2 processing intermediates on secreted invertase. J. Biol. Chem., 268, 12104-12115.
42. Vijayraghavan, U., Company, M. and Abelson, J. (1989) Isolation and characterization of pre-mRNA splicing mutants of Saccharomyces cerevisiae. Genes Dev., 3, 1206-16.
43. von Heijne, G. (1986) A new method for predicting signal sequence cleavage sites. Nucleic Acids Res., 14, 4683-4690.
44. 2-pyrophosphoryldolichol in intact but not disrupted castanospermine and swainsonine-resistant Chinese hamster ovary cells. J. Biol. Chem. 265, 2296-305.
45. Zufferey, R., Knauer, R., Burda, P, Stagljar, I., te Heesen, S., Lehle, L. and Aebi, M. (1995) STT3, a highly conserved protein required for yeast oligosaccharyl transferase activity in vitro. EMBO J., 14, 4949-4960.