Glycoengineering of the methylotrophic yeast Hansenula polymorpha for the production of glycoproteins with trimannosyl core N-glycan by blocking core oligosaccharide assembly

Biotechnology Journal

Volumn 3, Issue 5, 2008, Pages 659-668

  Oh, Doo Byoung ^a   Park, Jeong Seok ^a,b   Kim, Moo Woong ^a   Cheon, Seon Ah ^a   Kim, Eun Jung ^a   Moon, Hye Yun ^a   Kwon, Ohsuk ^a   Rhee, Sang Ki ^a   Kang, Hyun Ah ^a  

^a Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^b UNIVERSITY OF ILLINOIS   (United States)

Author keywords

ALG3; Glycoengineering; Hansenula polymorpha; Trimannosyl core N glycan

Indexed keywords

GLYCOENGINEERING; HANSENULA POLYMORPHA; TRIMANNOSYL CORE N-GLYCAN;

OLIGOSACCHARIDES; POLYPEPTIDES; PROTEINS; SYNTHESIS (CHEMICAL); YEAST;

BIOTECHNOLOGY;

DOLICHOL PHOSPHATE MANNOSE; DOLICHOL PHOSPHATE MANNOSE DEPENDENT ALPHA 1,3 MANNOSYLTRANSFERASE; GLYCOPROTEIN; MANNOSE; MANNOSIDASE; MANNOSYLTRANSFERASE; OLIGOSACCHARIDE;

ARTICLE; ASPERGILLUS; ASPERGILLUS SAITOI; CARBOHYDRATE SYNTHESIS; ENDOPLASMIC RETICULUM; FUNGAL GENETICS; FUNGAL METABOLISM; FUNGUS MUTATION; GENE DELETION; GENETIC ENGINEERING; HANSENULA POLYMORPHA; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; STRAIN DIFFERENCE; STRUCTURE ANALYSIS;

GENETIC ENHANCEMENT; GLYCOPROTEINS; MANNOSYLTRANSFERASES; MEMBRANE PROTEINS; OLIGOSACCHARIDES; PICHIA; POLYSACCHARIDES; PROTEIN ENGINEERING; SACCHAROMYCES CEREVISIAE PROTEINS;

ASPERGILLUS SAITOI; PICHIA ANGUSTA;

EID: 44949101441     PISSN: 18606768     EISSN: None     Source Type: Journal    
DOI: 10.1002/biot.200700252     Document Type: Article

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