Strong hybrid promoters and integrative expression/secretion vectors for quasi-constitutive expression of heterologous proteins in the yeast Yarrowia lipolytica

Journal of Molecular Microbiology and Biotechnology

Volumn 2, Issue 2, 2000, Pages 207-216

  Madzak, Catherine ^a   Tréton, Brigitte ^a   Blanchin Roland, Sylvie ^a  

^a AGROPARISTECH   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GALACTOSIDASE; CHYMOSIN; PROTEINASE; SUCROSE;

ARTICLE; CELL STRAIN; CLONING VECTOR; ESCHERICHIA COLI; FUNGAL GENETICS; FUNGUS GROWTH; GENE REPLICATION; GENETIC ENGINEERING; HYBRID GENE; NONHUMAN; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN SECRETION; PROTEIN SYNTHESIS; SECRETION; YARROWIA LIPOLYTICA;

ANIMALS; BASE SEQUENCE; BIOTECHNOLOGY; CATTLE; CHYMOSIN; CLONING, MOLECULAR; DNA PRIMERS; ENZYME PRECURSORS; GENE EXPRESSION; GENETIC VECTORS; PLASMIDS; PROMOTER REGIONS (GENETICS); RECOMBINANT PROTEINS; SACCHAROMYCETALES; TATA BOX;

BOVINAE; ESCHERICHIA COLI; FUNGI; YARROWIA LIPOLYTICA;

EID: 0344002683     PISSN: 14641801     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (39)

1. Barth, G, and Gaillardin, C 1996 Yarrowia lipolytica In Nonconventional yeasts in biotechnology, a handbook K Wolf, ed Springer-Verlag, Berlin-Heidelberg p 313-388
2. Bassel, J, and Mortimer, R 1973 Genetic analysis of mating type and alkane utilisation in Saccharomycopsis lipolytica. J Bacteriol 114 894-896
3. Blanchin-Roland, S, Cordero Otero, R, and Gaillardin, C 1994 Two upstream activation sequences control the expression of the XPR2 gene in the yeast Yarrowia lipolytica Mol Cell Biol 14 327-338
4. Boyer, H W, and Roulland-Dussoix, D 1969 A complementation analysis of the restriction and modification of DNA in Escherichia coli. J Mol Biol 41 459-472
5. Buckholz, R G, and Gleeson, MAG 1991 Yeast systems for the commercial production of heterologous proteins Bio/Technology 9 1067-1072
6. Cordero Otero, R, and Gaillardin, C. 1996 Dominant mutations affecting expression of pH-regulated genes in Yarrowia lipolytica Mol Gen Genet 252 311-319
7. Davidow, L S, Franke, A E., and De Zeeuw, J R 1986 Expression and secretion of heterologous proteins by Yarrowia lipolytica transformants European Patent Application EP 0 220 864 A1
8. Davidow, L S, O'Donnell, M M, Kaczmarek, F S, Pereira, D A., De Zeeuw, J R, and Franke, A E 1987 Cloning and sequencing of the alkaline extracellular protease gene of Yarrowia lipolytica J Bacteriol 169 4621-4629
9. Dominguez, A, Ferminan, E., Sanchez, M, Gonzalez, FJ, Pérez-Campo, F M, Garcia, S, Herrero, A B, San Vicente, A, Cabello, J, Prado, M, Iglesias, F J., Choupina, A, Burguillo, FJ, Fernandez-Lago, L, and Lopez, M C 1998 Non-conventional yeasts as hosts for heterologous protein production Internatl Microbiol 1 131-142
10. Fabre, E, Nicaud, J-M, Lopez, M-C, and Gaillardin, C 1991 Role of the proregion in the production and secretion of the Yarrowia lipolytica alkaline extracellular protease J Biol Chem 266 3782-3790
11. Fabre, E, Tharaud, C, and Gaillardin, C 1992. Intracellular transit of a yeast protease is rescued by trans-complementation with its prodomain J Biol Chem. 267 15049-15055
12. Franke, A E, Kaczmarek, F.S, Eisenhard, M.E, Geoghegan, K F, Danley, D E, De Zeeuw, J.R, O'Donnell, M M, Gollaher, M G Jr, and Davidow, LS 1988 Expression and secretion of bovine prochymosin in Yarrowia lipolytica In Dev in Ind Microbiol G Pierce, ed Elsevier, Amsterdam vol 29. p 43-57
13. Fournier, P, Guyaneux, L, Chasles, M, and Gaillardin, C 1991 Scarcity of ARS sequences isolated in a morphogenesis mutants of the yeast Yarrowia lipolytica. Yeast 7. 25-36
14. Fournier, P, Abbas, A, Chasles, M, Kudla, B, Ogrydziak, D M, Yaver, D, Xuan, J W, Peito, A, Ribet, A -M, Feynerol, C, He, F, and Gaillardin, C 1993 Colocalization of centromeric and replicative functions on autonomously replicating sequences isolated from the yeast Yarrowia lipolytica Proc Natl Acad Sc 90. 4912-4916
15. Hanahan, D 1985 Technics for transformation of Escherichia coli. In DNA cloning, a practical approach D M Glover, ed IRL Press, Oxford vol I p 109-135
16. Hamsa, P.V, and Chattoo, BB 1994 Cloning and growth-regulated expression of the gene encoding the hepatitis B virus middle surface antigen in Yarrowia lipolytica Gene 143. 165-170
17. Hoffman, C S, and Winston, F 1987 A ten-minute DNA preparation from yeast efficiently releases autonomous plasmids for transformation of Escherichia coli Gene 57 267-272
18. Klug, M J, and Markovetz, A J 1967 Degradation of hydrocarbons by members of the genus Candida II Oxydation of n-alkanes and 1-alkenes by Candida lipolytica J Bacteriol 93 1847-1851
19. Le Dall, M -T, Nicaud, J -M, and Gaillardin, C 1994. Multiple-copy integration in the yeast Yarrowia lipolytica Curr. Genet 26 38-44
20. Madzak, C, Blanchin-Roland, S, Cordero Otero, R, and Gaillardin, C 1999 Functional analysis of upstream regulating regions from the Yarrowia lipolytica XPR2 promoter Microbiol 145 75-87
21. Muller, S, Sandal, T, Kamp-Hansen, P, and Dalboge, H 1998 Comparison of expression systems in the yeasts Saccharomyces cerevisiae, Hansenula polymorpha, Kluyveromyces lactis, Schizosaccharomyces pombe and Yarrowia lipolytica Cloning of two novel promoters from Yarrowia lipolytica Yeast 14 1267-1283
22. Nicaud, J -M, Fabre, E, and Gaillardin, C 1989a Expression of invertase activity in Yarrowia lipolytica and its use as a selective marker Curr Genet 16 253-260
23. Nicaud, J -M, Fabre, E, Beckerich, J -M, Fournier, P, and Gaillardin, C 1989b Cloning, sequencing and amplification of the alkaline extracellular protease (XPR2) gene of the yeast Yarrowia lipolytica J Biotechnol 12 285-298
24. Nicaud, J -M, Fournier, P, La Bonnardière, C, Chasles, M, and Gaillardin, C 1991. Use of ars18 based vectors to increase protein production in Yarrowia lipolytica J Biotech. 19 259-270
25. Ogrydziak, D M, Demain, A L, and Tannenbaum, S R 1977 Regulation of extracellular protease production in Candida lipolytica Biochim Biophys Acta 497 525-538
26. Park, C S, Chang, C C, Kim J -Y, Ogrydziak, D M, and Ryu, D D Y 1997 Expression, secretion and processing of rice α-amylase in the yeast Yarrowia lipolytica J. Biol Chem 272 6876-6881
27. Raleigh, E A, Lech, K, and Brent, R 1989 Current Protocols in Molecular Biology, FM Ausubel et al., eds Publishing Associates and Wiley Interscience, New York
28. Sambrook, J, Fritsch, E F, and Maniatis, T 1989 Molecular cloning a laboratory manual, 2nd ed Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York
29. Scherer, S, and Davis, R W 1979 Replacement of chromosomes segments with altered DNA sequences constructed in vitro Proc Natl Acad Sc. 76 4951-4955
30. Sherman, F, Fink, G R, and Hicks, J 1986 Methods in yeast genetics Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York
31. Tharaud, C, Ribet, A -M, Costes, C, and Gaillardin, C 1992 Secretion of human blood coagulation factor XIIIa by the yeast Yarrowia lipolytica Gene 121 111-119
32. Tobe, S, Takami, T, Ikeda, S., and Mitsugi, K 1976. Production and some enzymatic properties of alkaline protease of Candida lipolytica Agric Biol Chem 40 1087-1092
33. Tréton, B, Le Dall, M -T, and Gaillardin, C. 1992 Complementation of Saccharomyces cerevisiae acid phosphatase mutation by a genomic sequence from the yeast Yarrowia lipolytica identifies a new phosphatase Curr. Genet. 22 345-355
34. Vernis, L., Abbas, A, Chasles, M, Gaillardin, C, Brun, C., Huberman, J A, and Fournier P 1997. An origin of replication and a centromere are both needed to establish a replicative plasmid in the yeast Yarrowia lipolytica Mol. Cell Biol 17 1995-2004
35. + transformants in sucrose media Pol J Food Nutr Sei 6/ 47 49-54
36. Xuan, J-W, Fournier, P, and Gaillardin, C 1988 Cloning of the LYS5 gene encoding saccharopine dehydrogenase from the yeast Yarrowia lipolytica by target integration Curr Genet. 14 15-21
37. Xuan, J-W, Fournier, P, Declerck, N, Chasles, M, and Gaillardin, C 1990 Overlapping reading frames at the LYS5 locus in the yeast Yarrowia lipolytica Mol Cell Biol. 10 4795-4806
38. Yamada, T, and Ogrydziak, D 1983 Extracellular acid protease produced by Saccharomycopsis lipolytica J Bacteriol 154 23-31
39. Yon, J, and Fried, M 1989 Precise gene fusion by PCR. Nuc. Acids Res 17 4895