A functional polymorphism at microRNA-629-binding site in the 3'-untranslated region of nbs1 gene confers an increased risk of lung cancer in southern and eastern chinese population

Carcinogenesis

Volumn 33, Issue 2, 2012, Pages 338-347

  Yang, Lei ^a   Li, Yinyan ^a   Cheng, Mei ^a   Huang, Dongsheng ^a   Zheng, Jian ^b   Liu, Bin ^a   Ling, Xiaoxuan ^a   Li, Qingchu ^a   Zhang, Xin ^a   Ji, Weidong ^a   Zhou, Yifeng ^b   Lu, Jiachun ^a  

^a GUANGZHOU MEDICAL UNIVERSITY   (China)

^b MEDICAL COLLEGE OF SOOCHOW UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

LUCIFERASE; MESSENGER RNA; MICRORNA; MICRORNA 629; NIBRIN; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; ADULT; AGE; ALLELE; ARTICLE; CANCER RISK; CANCER TISSUE; CASE CONTROL STUDY; CHINESE; CHROMATID; CHROMOSOME BREAKAGE; CONTROLLED STUDY; DRINKING BEHAVIOR; FAMILY HISTORY; FEMALE; GENE EXPRESSION REGULATION; GENETIC ASSOCIATION; GENETIC MODEL; GENETIC RISK; GENOTYPE; HETEROZYGOTE; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IONIZING RADIATION; LUNG CANCER; LYMPHOCYTE; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; POPULATION GENETICS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADIATION EXPOSURE; REPORTER GENE; RISK ASSESSMENT; SEX DIFFERENCE; SINGLE NUCLEOTIDE POLYMORPHISM; SMOKING; TRANSCRIPTION REGULATION; WESTERN BLOTTING; X RAY;

EID: 84863070560     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgr272     Document Type: Article

References (47)

1. Hoeijmakers, J.H. (2001) Genome maintenance mechanisms for preventing cancer. Nature, 411, 366-374.
2. Khanna, K.K. et al. (2001) DNA double-strand breaks: signaling, repair and the cancer connection. Nat. Genet., 27, 247-254.
3. Goodarzi, A.A. et al. (2008) ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin. Mol. Cell, 31, 167-177.
4. Marczynski, B. et al. (2011) DNA adducts and strand breaks in workers exposed to vapours and aerosols of bitumen: associations between exposure and effect. Arch. Toxicol., 85 (suppl. 1), S53-S64.
5. Asaithamby, A. et al. (2010) Mechanism of cluster DNA damage repair in response to high-atomic number and energy particles radiation. Mutat. Res., 711, 87-99.
6. Harper, J.V. et al. (2010) Radiation induced DNA DSBs: contribution from stalled replication forks? DNA Repair (Amst), 9, 907-913.
7. Nikolova, T. et al. (2010) Homologous recombination protects mammalian cells from replication-associated DNA double-strand breaks arising in response to methyl methanesulfonate. DNA Repair (Amst), 9, 1050-1063.
8. Hodgson, A. et al. (2011) Mre11 and Exo1 contribute to the initiation and processivity of resection at meiotic double-strand breaks made independently of Spo11. DNA Repair (Amst), 10, 138-148.
9. Yin, B. et al. (2008) The sticky business of histone H2AX in V(D)J recombination, maintenance of genomic stability, and suppression of lymphoma. Immunol. Res., 42, 29-40.
10. Lins, S. et al. (2009) Clinical variability and expression of the NBN c.657del5 allele in Nijmegen Breakage Syndrome. Gene, 447, 12-17.
11. Hu, Y. et al. (2011) RAP80-directed tuning of BRCA1 homologous recombination function at ionizing radiation-induced nuclear foci. Genes Dev., 25, 685-700.
12. Mahaney, B.L. et al. (2009) Repair of ionizing radiation-induced DNA double-strand breaks by non-homologous end-joining. Biochem. J., 417, 639-650.
13. Shen, M. et al. (2006) Polymorphisms in genes involved in DNA doublestrand break repair pathway and susceptibility to benzene-induced hematotoxicity. Carcinogenesis, 27, 2083-2089.
14. Qian, B. et al. (2010) Association of genetic polymorphisms in DNA repair pathway genes with non-small cell lung cancer risk. Lung Cancer, 73, 138-146.
15. Lu, J. et al. (2006) Polymorphisms and haplotypes of the NBS1 gene are associated with risk of sporadic breast cancer in non-Hispanic white women,or555 years. Carcinogenesis, 27, 2209-2216.
16. Margulis, V. et al. (2008) Genetic susceptibility to renal cell carcinoma: the role of DNA double-strand break repair pathway. Cancer Epidemiol. Biomarkers Prev., 17, 2366-2373.
17. Jelonek, K. et al. (2010) Association between single-nucleotide polymorphisms of selected genes involved in the response to DNA damage and risk of colon, head and neck, and breast cancers in a Polish population. J. Appl. Genet., 51, 343-352.
18. Ruan, Y. et al. (2011) Genetic polymorphisms in AURKA and BRCA1 are associated with breast cancer susceptibility in a Chinese Han population. J. Pathol., 225, 535-543.
19. Jackson, S.P. (2002) Sensing and repairing DNA double-strand breaks. Carcinogenesis, 23, 687-696.
20. Celeste, A. et al. (2002) Genomic instability in mice lacking histone H2AX. Science, 296, 922-927.
21. Williams, R.S. et al. (2009) Nbs1 flexibly tethers Ctp1 and Mre11-Rad50 to coordinate DNA double-strand break processing and repair. Cell, 139, 87-99.
22. Zhang, Y. et al. (2006) The role of NBS1 in DNA double strand break repair, telomere stability, and cell cycle checkpoint control. Cell Res., 16, 45-54.
23. Kim, S.T. et al. (2002) Involvement of the cohesin protein, Smc1, in Atmdependent and independent responses to DNA damage. Genes Dev., 16, 560-570.
24. Yazdi, P.T. et al. (2002) SMC1 is a downstream effector in the ATM/NBS1 branch of the human S-phase checkpoint. Genes Dev., 16, 571-582.
25. Nakanishi, K. et al. (2002) Interaction of FANCD2 and NBS1 in the DNA damage response. Nat. Cell Biol., 4, 913-920.
26. Iijima, K. et al. (2008) NBS1 regulates a novel apoptotic pathway through Bax activation. DNA Repair (Amst), 7, 1705-1716.
27. Digweed, M. et al. (2004) Nijmegen breakage syndrome: clinical manifestation of defective response to DNA double-strand breaks. DNA Repair (Amst), 3, 1207-1217.
28. Pardini, B. et al. (2009) NBN 657del5 heterozygous mutations and colorectal cancer risk in the Czech Republic. Mutat. Res., 666, 64-67.
29. Lu, M. et al. (2009) Association between the NBS1 E185Q polymorphism and cancer risk: a meta-analysis. BMC Cancer, 9, 124.
30. Park, S.L. et al. (2010) Associations between NBS1 polymorphisms, haplotypes and smoking-related cancers. Carcinogenesis, 31, 1264-1271.
31. Schuetz, J.M. et al. (2009) Genetic variation in the NBS1, MRE11, RAD50 and BLM genes and susceptibility to non-Hodgkin lymphoma. BMC Med. Genet., 10, 117.
32. Liu, B. et al. (2010) A functional variant (-1304T.G) in the MKK4 promoter contributes to a decreased risk of lung cancer by increasing the promoter activity. Carcinogenesis, 31, 1405-1411.
33. Lu, J. et al. (2011) The polymorphism and haplotypes of PIN1 gene are associated with the risk of lung cancer in southern and eastern Chinese populations. Hum. Mutat., 32, 1299-1308.
34. Yang, L. et al. (2011) A common genetic variant (97906C.A) of DAB2IP/ AIP1 is associated with an increased risk and early onset of lung cancer in Chinese males. PLoS One, 6, e26944.
35. Lu, J. et al. (2007) 172G.T variant in the 5' untranslated region of DNA repair gene RAD51 reduces risk of squamous cell carcinoma of the head and neck and interacts with a P53 codon 72 variant. Carcinogenesis, 28, 988-994.
36. Ernestos, B. et al. (2010) Increased chromosomal radiosensitivity in women carrying BRCA1/BRCA2 mutations assessed with the G2 assay. Int. J. Radiat. Oncol. Biol. Phys., 76, 1199-1205.
37. Bolzan, A.D. et al. (2008) Analysis of spontaneous and bleomycin-induced chromosome damage in peripheral lymphocytes of long-haul aircrew members from Argentina. Mutat. Res., 639, 64-79.
38. Uh, H.W. et al. (2007) Model selection based on logistic regression in a highly correlated candidate gene region. BMC Proc, 1 (suppl. 1), S114.
39. O'Gorman, T.W. et al. (1990) Statistical analysis of K 2 x 2 tables: a comparative study of estimators/test statistics for association and homogeneity. Environ. Health Perspect., 87, 103-107.
40. Knol, M.J. et al. (2007) Estimating interaction on an additive scale between continuous determinants in a logistic regression model. Int. J. Epidemiol., 36, 1111-1118.
41. Jiang, L. et al. (2011) Functional polymorphisms in the NBS1 gene and acute lymphoblastic leukemia susceptibility in a Chinese population. Eur. J. Haematol., 86, 199-205.
42. Zheng, J. et al. (2011) Functional NBS1 polymorphism is associated with occurrence and advanced disease status of nasopharyngeal carcinoma. Mol. Carcinog., 50, 689-696.
43. Choudhury, A. et al. (2008) Analysis of variants in DNA damage signalling genes in bladder cancer. BMC Med. Genet., 9, 69.
44. Meyer, P. et al. (2007) Molecular genetic analysis of NBS1 in German melanoma patients. Melanoma Res., 17, 109-116.
45. Fan, L.H. et al. (2010) [Study on the association between DNA double-strand break repair gene NBS1 polymorphisms and susceptibility on lung cancer.]. Zhonghua Liu Xing Bing Xue Za Zhi, 31, 213-217.
46. Navon, R. et al. (2009) Novel rank-based statistical methods reveal micro-RNAs with differential expression in multiple cancer types. PLoS One, 4, e8003.
47. Xu, Z. et al. (2009) SNPinfo: integrating GWAS and candidate gene information into functional SNP selection for genetic association studies. Nucleic Acids Res., 37, W600-W605.