A functional variant (-1304T>G) in the MKK4 promoter contributes to a decreased risk of lung cancer by increasing the promoter activity

Carcinogenesis

Volumn 31, Issue 8, 2010, Pages 1405-1411

  Liu, Bin ^a   Chen, Dianke ^b   Yang, Lei ^a   Li, Yinyan ^a   Ling, Xiaoxuan ^a   Liu, Lin ^a   Ji, Weidong ^a   Wei, Yisheng ^a,b   Wang, Jianping ^b   Wei, Qingyi ^c   Wang, Lei ^b   Lu, Jiachun ^a  

^a GUANGZHOU MEDICAL UNIVERSITY   (China)

^b SUN YAT SEN UNIVERSITY   (China)

^c UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LUCIFERASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4;

APOPTOSIS; ARTICLE; BODY MASS; CANCER SUSCEPTIBILITY; CANCER TISSUE; CONTROLLED STUDY; FEMALE; GENE; GENETIC POLYMORPHISM; GENETIC TRANSCRIPTION; GENETIC VARIABILITY; GENOTYPE; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; INFLAMMATION; LUNG CANCER; LUNG CARCINOGENESIS; MAJOR CLINICAL STUDY; MALE; MKK4 GENE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; REGULATORY MECHANISM; RISK REDUCTION; SIGNAL TRANSDUCTION;

AGED; CARRIER STATE; CELL LINE, TUMOR; FEMALE; GENES, REPORTER; GENETIC VARIATION; GENOTYPE; HUMANS; LINKAGE DISEQUILIBRIUM; LUCIFERASES; LUNG NEOPLASMS; MALE; MAP KINASE KINASE 4; MIDDLE AGED; PLASMIDS; POLYMORPHISM, GENETIC; POLYMORPHISM, SINGLE NUCLEOTIDE; PROMOTER REGIONS, GENETIC; REFERENCE VALUES; RISK FACTORS; TRANSFECTION;

EID: 77955353888     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgq126     Document Type: Article

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