Pluripotency factor-mediated expression of the leptin receptor (OB-R) links obesity to oncogenesis through tumor-initiating stem cells

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 3, 2012, Pages 829-834

  Feldman, Douglas Edmund ^a   Chen, Chialin ^a   Punj, Vasu ^a,b   Tsukamoto, Hidekazu ^b,c   Machida, Keigo ^a,b  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LEPTIN; LEPTIN RECEPTOR; LEUKEMIA INHIBITORY FACTOR; MESSENGER RNA; OCTAMER TRANSCRIPTION FACTOR 4; STAT3 PROTEIN; TRANSCRIPTION FACTOR SOX2;

ANIMAL CELL; ARTICLE; CANCER GROWTH; CANCER STEM CELL; CELL EXPANSION; CONTROLLED STUDY; EMBRYO; EMBRYONIC STEM CELL; GENE EXPRESSION REGULATION; HORMONE SYNTHESIS; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; OBESITY; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; TRANSCRIPTION INITIATION; TUMOR INITIATING STEM CELL;

ANIMALS; ANTIGENS, CD; CELL LINE, TUMOR; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; GLYCOPROTEINS; HUMANS; LEPTIN; MICE; MICE, INBRED C57BL; NEOPLASTIC STEM CELLS; OBESITY; OCTAMER TRANSCRIPTION FACTOR-3; PEPTIDES; PLURIPOTENT STEM CELLS; RECEPTORS, LEPTIN; SOXB1 TRANSCRIPTION FACTORS;

MUS;

EID: 84863042920     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1114438109     Document Type: Article

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