Clinical outcomes of traditional Chinese medicine compound formula in treating sleep-disordered breathing patients

American Journal of Chinese Medicine

Volumn 40, Issue 1, 2012, Pages 11-24

  Wu, Yi Hong ^a,b   Wei, Yi Chia ^a   Tai, Yu Shan ^a   Chen, Kuan Jen ^a   Li, Hsueh Yu ^a,c  

^a CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^b CHANG GUNG UNIVERSITY   (Taiwan)

^c CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

Author keywords

Excessive Daytime Sleepiness; Herbs; Obstructive Sleep Apnea; Sleep Disordered Breathing; Snoring; Traditional Chinese Medicine

Indexed keywords

ANEMARRHENA EXTRACT; ANGELICA ROOT EXTRACT; ASARI EXTRACT; ATRACTYLODIS MACROCEPHALAE EXTRACT; BUPLEURUM ROOT EXTRACT; CIMICIFUGA RACEMOSA EXTRACT; CITRI RETICULATAE EXTRACT; COPTIS RHIZOME EXTRACT; CURCUMA EXTRACT; FORSYTHIA EXTRACT; GENTIAN EXTRACT; GINSENG EXTRACT; GLYCYRRHIZA EXTRACT; GLYCYRRHIZAE EXTRACT; GLYCYRRHIZAE PREPARATA EXTRACT; JUJUBAE EXTRACT; LAMINARIAE EXTRACT; MAGNOLIA EXTRACT; PAEONIA RADIX; PINELLIA EXTRACT; PINELLIAE EXTRACT; PLANT EXTRACT; PLATYCODI EXTRACT; PORIA EXTRACT; PUERARIA EXTRACT; SCUTELLARIAE RADIX; SPARGANII EXTRACT; TRICHOSANTHES EXTRACT; UNCLASSIFIED DRUG; UNINDEXED DRUG; XANTHII EXTRACT;

ADULT; ARTICLE; CHINESE MEDICINE; CLINICAL EFFECTIVENESS; DRUG SAFETY; DRUG SCREENING; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; NASAL UNBLOCKING HERB; SAN ZHONG KUI JIAN TANG; SLEEP DISORDERED BREATHING; TREATMENT OUTCOME;

ACTIVITIES OF DAILY LIVING; ADULT; DISORDERS OF EXCESSIVE SOMNOLENCE; DRUGS, CHINESE HERBAL; FEMALE; HUMANS; MALE; MEDICINE, CHINESE TRADITIONAL; MIDDLE AGED; PHYTOTHERAPY; QUALITY OF LIFE; RETROSPECTIVE STUDIES; SLEEP; SLEEP APNEA SYNDROMES; SNORING; TAIWAN;

EID: 84863035251     PISSN: 0192415X     EISSN: None     Source Type: Journal    
DOI: 10.1142/S0192415X12500024     Document Type: Article

References (52)

1. Asl, M.N. and H. Hosseinzadeh. Review of pharmacological effects of Glycyrrhiza sp and its bio-active compounds. Phytother. Res. 22: 709-724, 2008. (Pubitemid 351955567)
2. Baek, J.A., Y.D. Lee, C.B. Lee, H.K. Go, J.P. Kim, J.J. Seo, Y.K. Rhee, A.M. Kim and D.J. Na. Extracts of Magnoliae flos inhibit inducible nitric oxide synthase via ERK in human respiratory epithelial cells. Nitric Oxide-Biol. Ch. 20: 122-128, 2009.
3. Chen, F.P., T.J. Chen, Y.Y. Kung, Y.C. Chen, L.F. Chou, F.J. Chen and S.J. Hwang. Use frequency of traditional Chinese medicine in Taiwan. BMC Health Serv. Res. 7: 26, 2007.
4. Chen, N.H., M.W. Johns, H.Y. Li, C.C. Chu, S.C. Liang, Y.H. Shu, M.L. Chuang and P.C. Wang. Validation of a Chinese version of the Epworth sleepiness scale. Qual. Life Res. 11: 817-821, 2002a. (Pubitemid 35388178)
5. Chen, N.H., H.Y. Li, R.E. Gliklich, C.C. Chu, S.C. Liang and P.C. Wang. Validation assessment of the Chinese version of the Snore Outcomes Survey. Qual. Life Res. 11: 601-607, 2002b. (Pubitemid 34876134)
6. Chervin, R.D., K.H. Archbold, J.E. Dillon, P. Panahi, K.J. Pituch, R.E. Dahl and C. Guilleminault. Inattention, hyperactivity, and symptoms of sleep-disordered breathing. Pediatrics 109: 449-456, 2002. (Pubitemid 34177508)
7. Chuang, L.P., S.C. Hsu, S.W. Lin, W.S. Ko, N.H. Chen and Y.H. Tsai. Prevalence of snoring and witnessed apnea in Taiwanese adults. Chang Gung Med. J. 31: 175-181, 2008.
8. Cicero, A.F. and S. Ertek. Metabolic and cardiovascular effects of berberine: from preclinical evidences to clinical trial results. Clin. Lipidol. 4: 553-563, 2009.
9. Clarenbach, C.F., M. Kohler, O. Senn, R. Thurnheer and K.E. Bloch. Does nasal decongestion improve obstructive sleep apnea? J. Sleep Res. 17: 444-449, 2008.
10. Cyong, J. and Y. Otsuka. A pharmacological study of the anti-inflammatory activity of Chinese herbs. A review. Acupunct. Electrother. Res. 7: 173-202, 1982. (Pubitemid 13205621)
11. Dai, S.J., Y. Ren, L. Shen and D.W. Zhang. New alkaloids from Forsythia suspensa and their anti-inflammatory activities. Planta Med. 75: 375-377, 2009.
12. Friedman, M., H.C. Lin, B. Gurpinar and N.J. Joseph. Minimally invasive single-stage multilevel treatment for obstructive sleep apnea/hypopnea syndrome. Laryngoscope 117: 1859-1863, 2007. (Pubitemid 47508723)
13. Georgalas, C., The role of the nose in snoring and obstructive sleep apnoea: an update. Eur. Arch. Otorhinolaryngol. 268: 1365-1373, 2011.
14. Giles, T.L., T.J. Lasserson, B.H. Smith, J. White, J. Wright and C.J. Cates. Continuous positive airways pressure for obstructive sleep apnoea in adults. Cochrane Database Syst. Rev. 3: CD001106, 2006.
15. Gliklich, R.E. and P.C. Wang. Validation of the snore outcomes survey for patients with sleep-disordered breathing. Arch. Otolaryngol. Head Neck Surg. 128: 819-824, 2002. (Pubitemid 34755315)
16. Goldbart, A.D., J.L. Goldman, M.C. Veling and D. Gozal. Leukotriene modifier therapy for mild sleep-disordered breathing in children. Am. J. Respir. Crit. Care Med. 172: 364-370, 2005. (Pubitemid 41026148)
17. Han, A.R., H.J. Kim, M. Shin, M. Hong, Y.S. Kim and H. Bae. Constituents of Asarum sieboldii with inhibitory activity on lipopolysaccharide (LPS)-induced NO production in BV-2 microglial cells. Chem. Biodivers. 5: 346-351, 2008.
18. Hao, Y., D. Li and X. Piao. Forsythia suspensa extract alleviates hypersensitivity induced by soybean beta-conglycinin in weaned piglets. J. Ethnopharmacol. 128: 412-418, 2010.
19. Hong, S.H., H.J. Jeong and H.M. Kim. Inhibitory effects of Xanthii fructus extract on mast cellmediated allergic reaction in murine model. J. Ethnopharmacol. 88: 229-234, 2003.
20. Jiang, R.W., K.M. Lau, H.M. Lam, W.S. Yam, L.K. Leung, K.L. Choi, M.M. Waye, T.C. Mak, K.S. Woo and K.P. Fung. A comparative study on aqueous root extracts of Pueraria thomsonii and Pueraria lobata by antioxidant assay and HPLC fingerprint analysis. J. Ethnopharmacol. 96: 133-138, 2005. (Pubitemid 39575042)
21. Johns, M.W., A new method for measuring daytime sleepiness: the Epworth sleepiness scale. Sleep 14: 540-545, 1991.
22. Kang, O.H., H.S. Chae, Y.C. Oh, J.G. Choi, Y.S. Lee, H.J. Jang, J.H. Kim, Y.C. Kim, D.H. Sohn, H. Park and D.Y. Kwon. Anti-nociceptive and anti-inflammatory effects of Angelicae dahuricae radix through inhibition of the expression of inducible nitric oxide synthase and NO production. Am. J. Chin. Med. 36: 913-928, 2008.
23. Kheirandish-Gozal, L. and D. Gozal. Intranasal budesonide treatment for children with mild obstructive sleep apnea syndrome. Pediatrics 122: e149-155, 2008.
24. Koskenvuo, M., J. Kaprio, M. Partinen, H. Langinvainio, S. Sarna and K. Heikkila. Snoring as a risk factor for hypertension and angina pectoris. Lancet 1: 893-896, 1985. (Pubitemid 15009181)
25. Koskenvuo, M., J. Kaprio, T. Telakivi, M. Partinen, K. Heikkila and S. Sarna. Snoring as a risk factor for ischaemic heart disease and stroke in men. Br. Med. J. (Clin. Res. Ed.) 294: 16-19, 1987. (Pubitemid 17224631)
26. Kwon, K.B., E.K. Kim, M.J. Han, B.C. Shin, Y.K. Park, K.S. Kim, Y.R. Lee, J.W. Park, B.H. Park and D.G. Ryu. Induction of apoptosis by Radix Paeoniae Alba extract through cytochrome c release and the activations of caspase-9 and caspase-3 in HL-60 cells. Biol. Pharm. Bull. 29: 1082-1086, 2006. (Pubitemid 43845464)
27. Li, G. Secret Records of the Orchid Chamber (Lan Shi Mi Cang). People's Medical Publishing House, Beijing, China, 1957.
28. Li, H.Y., L.A. Lee, P.C. Wang, N.H. Chen, Y. Lin and T.J. Fang. Nasal surgery for snoring in patients with obstructive sleep apnea. Laryngoscope 118: 354-359, 2008. (Pubitemid 351640216)
29. Liao, H.F., M.C. Lu, H.C. Chang, C.C. Wei, C.H. Kao, Z.H. Chen, C.C. Huang and C. Li, Effects of herbal medicinal formulas on suppressing viral replication and modulating immune responses. Am. J. Chin. Med. 38: 173-190, 2010.
30. Lim, J., T.J. Lasserson, J. Fleetham and J. Wright. Oral appliances for obstructive sleep apnoea. Cochrane Database Syst. Rev. 1: CD004435, 2006.
31. Lu, J.F., H.M. Tseng and Y.J. Tsai. Assessment of health-related quality of life in Taiwan (I): development and psychometric testing of SF-36 Taiwan version. Taiwan J. Public Health 22: 501-511, 2003.
32. Lu, T., X.L. Piao, Q. Zhang, D. Wang, X.S. Piao and S.W. Kim. Protective effects of Forsythia suspensa extract against oxidative stress induced by diquat in rats. Food Chem. Toxicol. 48: 764-770, 2010.
33. Magalang, U.J. and M.J. Mador, Behavioral and pharmacologic therapy of obstructive sleep apnea. Clin. Chest Med. 24: 343-353, 2003. (Pubitemid 36617637)
34. Matsukawa, K., M. Ogata, T. Hikage, H. Minami, Y. Shimotai, Y. Saitoh, T. Yamashita, A. Ouchi, R. Tsutsumi, T. Fujioka and K.I. Tsutsumi. Antiproliferative activity of root extract from gentian plant (Gentiana triflora) on cultured and implanted tumor cells. Biosci. Biotechnol. Biochem. 70: 1046-1048, 2006.
35. McNicholas, W.T. The nose and OSA: variable nasal obstruction may be more important in pathophysiology than fixed obstruction. Eur. Respir. J. 32: 3-8, 2008.
36. Mulgrew, A.T., C.F. Ryan, J.A. Fleetham, R. Cheema, N. Fox, M. Koehoorn, J.M. Fitzgerald, C. Marra and N.T. Ayas. The impact of obstructive sleep apnea and daytime sleepiness on work limitation. Sleep Med. 9: 42-53, 2007. (Pubitemid 350192902)
37. Powell, N.B., K.B. Schechtman, R.W. Riley, C. Guilleminault, R.P.Y. Chiang and E.M. Weaver. Sleepy driver near-misses may predict accident risks. Sleep 30: 331-342, 2007. (Pubitemid 46494409)
38. Rojas, A., M. Bah, J.I. Rojas and D.M. Gutierrez. Smooth muscle relaxing activity of gentiopicroside isolated from Gentiana spathacea. Planta Med. 66: 765-767, 2000. (Pubitemid 32038938)
39. Ryan, S., C.T. Taylor and W.T. McNicholas. Systemic inflammation: a key factor in the pathogenesis of cardiovascular complications in obstructive sleep apnoea syndrome? Thorax 64: 631-636, 2009.
40. Shen, Y., E.C.K. Pang, C.C.L. Xue, Z.Z. Zhao, J.G. Lin and C.G. Li. Inhibitions of mast cell-derived histamine release by different Flos Magnoliae species in rat peritoneal mast cells. Phytome-dicine 15: 808-814, 2008.
41. Smith, I., T.J. Lasserson and J. Wright. Drug therapy for obstructive sleep apnoea in adults. Cochrane Database Syst. Rev. CD003002, 2006.
42. Sundaram, S., S.A. Bridgman, J. Lim and T.J. Lasserson. Surgery for obstructive sleep apnoea. Cochrane Database Syst. Rev. CD001004, 2005.
43. Tohda, C., N. Nakayama, F. Hatanaka and K. Komatsu. Comparison of anti-inflammatory activities of six Curcuma rhizomes: a possible curcuminoid-independent pathway mediated by Curcuma phaeocaulis extract. Evid Based Complement. Alternat. 3: 255-260, 2006.
44. Tseng, H.M., J.F. Lu and Y.J. Tsai. Assessment of health-related quality of life in Taiwan (II): norming and validation of SF-36 Taiwan version. Taiwan J. Public Health 22: 512-518, 2003.
45. Vgontzas, A.N., E. Zoumakis, H.M. Lin, E.O. Bixler, G. Trakada and G.P. Chrousos. Marked decrease in sleepiness in patients with sleep apnea by etanercept, a tumor necrosis factor-alpha antagonist. J. Clin. Endocrinol. Metab. 89: 4409-4413, 2004. (Pubitemid 39244447)
46. Ware, J.E. Jr. and C.D. Sherbourne. The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection. Med. Care 30: 473-483, 1992.
47. Woodson, B.T. and R. Franco. Physiology of sleep disordered breathing. Otolaryngol. Clin. North Am. 40: 691-711, 2007. (Pubitemid 46990406)
48. World Health Organization, Regional Office for the Western Pacific. WHO International Standard Terminologies on Traditional Medicine in the Western Pacific Region. World Health Organization Regional Office for the Western Pacific, Manila, 2007.
49. Young, T., M. Palta, J. Dempsey, J. Skatrud, S. Weber and S. Badr. The occurrence of sleep-disordered breathing among middle-aged adults. N. Engl. J. Med. 328: 1230-1235, 1993. (Pubitemid 23115702)
50. Young, T., L. Finn, P.E. Peppard, M. Szklo-Coxe, D. Austin, F.J. Nieto, R. Stubbs and K.M. Hla. Sleep disordered breathing and mortality: eighteen-year follow-up of the Wisconsin sleep cohort. Sleep 31: 1071-1078, 2008.
51. Zhang, J.Y., M.Y. Zhang, K. Sugahara, Y. Sagara, Z.Z. Meng, S.X. Xu and H. Kodama. Effect of steroidal saponins of Anemarrhenae rhizoma on superoxide generation in human neutrophils. Biochem. Biophys. Res. Commun. 259: 636-639, 1999. (Pubitemid 29335585)
52. Zhou, X.R., N. Yang, L.M. Lu, Q. Ding, Z.J. Jiao, Y. Zhou and K.Y. Chou. Up-regulation of IL-10 expression in dendritic cells is involved in Trichosanthin-induced immunosuppression. Immunol. Lett. 110: 74-81, 2007. (Pubitemid 46678231)