Physiology of Sleep Disordered Breathing

Otolaryngologic Clinics of North America

Volumn 40, Issue 4, 2007, Pages 691-711

  Woodson, B Tucker ^a   Franco, Rose ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AIRWAY DYNAMICS; AIRWAY OBSTRUCTION; AROUSAL; CONSCIOUSNESS; CRANIOFACIAL MALFORMATION; DYNAMICS; ELECTROMYOGRAPHY; HUMAN; LUNG VOLUME; MORPHOLOGY; MUSCLE CONTRACTION; NEUROMUSCULAR FUNCTION; NOSE OBSTRUCTION; PATHOGENESIS; PERIPHERAL NERVOUS SYSTEM; PHARYNX DISEASE; REVIEW; SLEEP APNEA SYNDROME; STARLING LAW; SURFACE TENSION; VASCULARIZATION;

AIRWAY RESISTANCE; CEPHALOMETRY; HUMANS; MOUTH BREATHING; NASAL OBSTRUCTION; OTORHINOLARYNGOLOGIC DISEASES; PALATE, SOFT; PHARYNX; POLYSOMNOGRAPHY; SLEEP APNEA, OBSTRUCTIVE; SLEEP STAGES;

EID: 34250801500     PISSN: 00306665     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.otc.2007.04.002     Document Type: Review

References (59)

1. Weitzman E.D., Pollak C.P., Borowiecki B.B., et al. The hypersomnia-sleep apnea syndrome: site and mechanism of upper airway obstruction. In: Guilleminault C., and Dements W.C. (Eds). Sleep apnea syndromes, Kroc Foundation Series vol. 11 (1978), Alan R Liss Inc., New York 235-248
2. Guilleminault C., Hill M., Simmons F.B., et al. Passive constriction of the upper airway during central apneas: fiberoptic and EMG investigations. Respir Physiol 108 (1997) 11-22
3. Remmers J.E., deGroot W.J., Sauerland E.K., et al. Pathogenesis of upper airway occlusion during sleep. J Appl Physiol 44 (1978) 931-938
4. Sauerland E.K., and Harper R.M. The human tongue during sleep: electromyographic activity of the genioglossus muscle. Exp Neurol 51 (1976) 160-170
5. Jordan A., White D.P., et al. Respiratory control stability and upper airway collapsibility in men and women with obstructive sleep apnea. J Appl Physiol 99 (2005) 2020-2027
6. Lieberman D.E., and Mc Carthy R.C. The ontogeny of cranial base angulation in humans and chimpanzees and its implications for reconstructing pharyngeal dimensions. J Hum Evol 36 (1999) 487-517
7. Malhotra A., Pillar G., Fogel R.B., et al. Pharyngeal pressure and flow effects on genioglossus activation in normal subjects. Am J Respir Crit Care Med 165 (2002) 71-77
8. Pae E.K., Lowe A.A., and Fleetham J.A. A role of pharyngeal length in obstructive sleep apnea patients. Am J Orthod Dentofacial Orthop 111 (1997) 12-17
9. Galvin J.R., Rooholamini S.A., and Standford W. Obstructive sleep apnea: diagnosis with ultrafast CT. Radiology 171 (1989) 775-778
10. Isono S., Remmers J., Tanaka A., et al. Anatomy of the pharynx in patients with obstructive sleep apnea and in normal subjects. J Appl Physiol 82 (1997) 1319-1326
11. Dempsy J.A., Skatrud J.B., Jacques A.J., et al. Anatomical determinates of sleep disordered breathing across the spectrum of clinical and non-clinical subjects. Chest 122 (2002) 840-851
12. Do K., Ferreyra H., Healy J., et al. Does tongue size differ between patients with and without sleep-disordered breathing?". Laryngoscope 110 (2000) 1552-1555
13. Lyberg T., Krogstad O., and Djupesland G. Cephalometric analysis in patients with obstructive sleep apnea syndrome: skeletal morphology. J Laryngol Otol 103 (1989) 287-292
14. Will M.J., Ester M.S., Ramirez S.G., et al. Comparison of cephalometric analysis with ethnicity in obstructive sleep apnea syndrome. Sleep 18 (1995) 873-875
15. Aren R., McDonough J.M., Costarino A.T., et al. Magnetic resonance imaging of the upper airway structure of children with obstructive sleep apnea syndrome. Am J Respir Crit Care Med 164 (2001) 698-703
16. Zucconi M., Caprioglio A., Calori G., et al. Craniofacial modifications in children with habitual snoring and obstructive sleep apnoea: a case control study. Eur Respir J 13 (1999) 411-417
17. Bradley T., Brown I., Grossman R., et al. Pharyngeal size in snorers, nonsnorers, and patients with obstructive sleep apnea. N Engl J Med 315 (1986) 1327-1331
18. Kryger M., Felipe L., Holder D., et al. The sleep deprivation syndrome of the obese patient-a problem of periodic nocturnal upper airway obstruction. Am J Med 56 (1974) 531-539
19. Mortimore I., Marshall I., Wraith P., et al. Neck and total body fat deposition in non-obese and obese patients with obstructive sleep apnea compared with that in control subjects. Am J Respir Crit Care Med 157 (1998) 280-283
20. Young T., Finn L., and Kim H. Nasal obstruction as a risk factor for sleep-disordered breathing. Allergy Clin Immunol 99 (1997) 757-762
21. Meurice J., Marc I., Carrier G., et al. Effects of mouth opening on upper airway collapsibility in normal sleeping subjects. Am J Respir Crit Care Med 153 (1996) 255-259
22. Schwab R.J., Gefter W.B., Hoffman E.A., et al. Dynamic upper airway imaging during respiration in normal subjects and patients with sleep disordered breathing. Am Rev Respir Dis 148 (1993) 1385-1400
23. Schwab R.J., Parirstein M., Pierson R., et al. Identification of upper airway anatomic risk factors for obstructive sleep apnea with volumetric MRI. Am J Respir Crit Care Med 167 9 (2003) 1176-1180
24. Redline S., Tishler P.V., Hans M.G., et al. Differences in sleep disordered breathing in African Americans and Caucasians. Am J Respir Crit Care Med 155 (1997) 186-192
25. Rodenstein D.O., Dooms G., Thomas Y., et al. Pharyngeal shape and dimensions in healthy subjects, snorers, and patients with obstructive sleep apnoea. Thorax 45 (1990) 723-727
26. Leiter J.C. Upper airway shape. Is it important in the pathogenesis of obstructive sleep apnea?. Am J Respir Crit Care Med 153 (1996) 894-898
27. Beaumont M., Fodil R., Isabey D., et al. Gravity effects on upper airway area and lung volumes during parabolic flight. J Appl Physiol 84 5 (1998) 1639-1645
28. Schwartz A.R., Smith P.L., Wise R.A., et al. Induction of upper aiway occlusion in sleeping individuals with subatmospheric nasal pressure. J Appl Physiol 64 (1988) 535-542
29. Fogel R., Malhotra A., Pillar G., et al. Genioglossal activation in patients with obstructive sleep apnea versus control subjects-mechanisms of muscle control. Am J Respir Crit Care Med 164 (2001) 2025-2030
30. Jokic R., Klimaszewski A., Mink J., et al. Surface tension forces in sleep apnea: the role of a soft tissue lubricant-a randomized double-blind, placebo-controlled trial. Am J Respir Crit Care Med 157 (1998) 1522-1525
31. Shepard J., Pevernagie D., Stanson A., et al. Effects of changes in central venous pressure on upper airway size in patients with obstructive sleep apnea. Am J Respir Crit Care Med 153 (1996) 250-254
32. Stanescu D., Kostinavev S., Sonna A., et al. Expiratory flow limitation during sleep in heavy snorers and obstructive sleep apnea patients. Eur Respir J 9 (1996) 2116-2121
33. Kimoff R.J., Cheong T.H., Olha A.E., et al. Mechanisms of apnea termination in obstructive sleep apnea: role of chemoreceptor and mechanoreceptor stimuli. Am J Respir Crit Care Med 149 (1994) 707-714
34. Tuck S., and Remmers J. Mechanical properties of the passive pharynx in Vietnamese pot-bellied pigs. II. Dynamics. J Appl Physiol 92 (2002) 2236-2244
35. Van de Graaff W. Thoracic traction on the trachea: mechanisms and magnitude. J Appl Physiol 70 3 (1991) 1328-1336
36. Lofasa F., Lorino A.M., Fodil R., et al. Heavy snoring with upper airway resistance syndrome may induce positive end-expiratory pressure. J Appl Physiol 85 (1998) 860-866
37. Badr S.M., Dawak A., Skatrud J.B., et al. Effect of induced hypocapnic hypopnea on upper airway patency in humans during NREM sleep. Respir Physiol 110 (1997) 33-45
38. Rowley J.A., Sannders C.S., Zahn B.R., et al. Effect of REM sleep on retroglossal cross-sectional area and compliance in normal subjects. J Appl Physiol 91 1 (2001) 239-248
39. Woodson B.T. Expiratory pharyngeal airway obstruction during sleep: a multiple element model. Laryngoscope 113 (2003) 1450-1459
40. Morrell M.J., Arabi Y., Zahn B., et al. Progressive retropalatal narrowing preceding obstructive apnea. Am J Respir Crit Care Med 158 (1998) 1974-1981
41. Series F. Upper airway muscles awake and asleep. Sleep Med Rev 6 (2002) 195-212
42. Van Lunteren E. Muscles of the pharynx: structural and contractile properties. Ear Nose Throat J 72 (1993) 27-29
43. Horner R. Impact of brainstem sleep mechanisms on pharyngeal motor control. Respir Physiol 119 (2000) 113-121
44. Strohl K.P., Hensley M.J., Hallet M., et al. Activation of upper airway muscles before onset of inspiration in normal humans. J Appl Physiol 53 (1983) 87-98
45. Malhotra A., Huang Y., Gogel R., et al. The male predisposition to pharyngeal collapse: importance of airway length. Am J Respir Crit Care Med 166 (2002) 13888-13895
46. Martin S., Marshall I., and Douglas N. The effect of posture on airway caliber with the sleep-apnea/hypopnea syndrome. Am J Respir Crit Care Med 152 (1995) 721-724
47. Mezzanote W.S., Tangle D.J., and White D.P. Influence of sleep onset on upper-airway muscle activity in apnea patients versus normal controls. Am Rev Respir Crit Care Med 153 (1996) 1880-1887
48. Mezzanote W.S., Tangle D.J., and White D.P. Waking genioglossal electromyogram in sleep apnea patients versus normala controls (a neuromuscular compensation mechanism). J Clin Invest 89 (1992) 1571-1579
49. Schwab R.J., Gupta K.B., Gefter W.B., et al. Upper airway and soft tissue anatomy in normal subjects and patients with sleep-disordered breathing. significance of the lateral pharyngeal walls. Am J Respir Crit Care Med 152 (1995) 1673-1689
50. Kuna S.T., Deepak G.B., and Ryckman C. Effect of nasal airway positive pressure on upper airway size and configuration. Am Rev Respir Dis 138 (1988) 969-975
51. Van der Touw T., Crawford A.B.H., and Wheatley J.R. Effects of a synthetic lung surfactant on pharyngeal patency in awake human subjects. J Appl Physiol 79 (1997) 78-85
52. Dempsey J., Smith C., Harms C., et al. Sleep and breathing state of the art review: sleep-induced breathing instability. Sleep 19 3 (1996) 236-247
53. Deegan P.C., Nolan P., Carey M., et al. Effects of positive airway pressure on upper airway dilator muscle activity and ventilatory timing. J Appl Physiol 81 1 (1996) 470-479
54. Liistro G., Stanescu D., Veriter C., et al. Upper airway anesthesia induces airflow limitation in awake humans. Am Rev Respir Dis 146 (1992) 581-585
55. Friberg D. Heavy snorer's disease: a progressive local neuropathy. Acta Otolaryngol 119 8 (1999) 925-933
56. Petrof B.J., Pack A.I., Kelly A.M., et al. Pharyngeal myopathy of loaded upper airway in dogs with sleep apnea. J Appl Physiol 76 4 (1994) 1746-1752
57. Woodson B.T., Garancis J.C., and Toohill R.J. Histopathologic changes in snoring and obstructive sleep apnea syndrome. Laryngoscope 1010 (1991) 1318-1322
58. Sériès F., Cote C., and St. Pierre S. Dysfunctional mechanical coupling of upper airway tissues in sleep apnea syndrome. Am J Respir Crit Care Med 159 (1999) 1551-1555
59. Series F., and Marc I. Influence of lung volume dependence of upper airway resistance during continuous negative airway pressure. J Appl Physiol 77 (1994) 840-844