Effects of herbal medicinal formulas on suppressing viral replication and modulating immune responses

American Journal of Chinese Medicine

Volumn 38, Issue 1, 2010, Pages 173-190

  Liao, Hui Fen ^a   Lu, Min Chi ^b   Chang, Hon Chou ^b   Wei, Cheng Chung ^b   Kao, Chih Hsiung ^c   Chen, Zong Huei ^a   Huang, Chin Chin ^a   Li, Ching ^a  

^a NATIONAL CHIAYI UNIVERSITY   (Taiwan)

^b CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^c ST MARTIN DE PORRES HOSPITAL   (Taiwan)

Author keywords

Antiviral activity; Chui Uren Chine; Immunomodulation; M todo canova; Radix isatidis; Traditional chinese medicines; Viola yedoensis makino

Indexed keywords

CHUI UREN CHIEN; HERBACEOUS AGENT; IMMUNOGLOBULIN G; ISATIDIS INDIGOTICA EXTRACT; METODO CANOVA; NITRIC OXIDE; UNCLASSIFIED DRUG; VIOLA YEDOENSIS EXTRACT; ANTIVIRUS AGENT; CHEMOKINE; CYTOKINE; IMMUNOLOGIC FACTOR; MATERIA MEDICA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG POTENCY; ENTEROVIRUS 71; HERPES SIMPLEX VIRUS 1; HUMAN; HUMAN CELL; IMMUNE DEFICIENCY; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOMODULATION; ISATIDIS INDIGOTICA; LIVER TOXICITY; MACROPHAGE ACTIVATION; MEDICINAL PLANT; MONOCYTE; MOUSE; NEPHROTOXICITY; NEUROBLASTOMA CELL; NONHUMAN; VIOLA YEDOENSIS; VIRUS IMMUNITY; VIRUS REPLICATION; ANIMAL; BAGG ALBINO MOUSE; BIOSYNTHESIS; BLOOD; ENTEROVIRUS; ENTEROVIRUS INFECTION; HERPES VIRUS INFECTION; MACROPHAGE; MONONUCLEAR CELL; TUMOR CELL LINE;

ANIMALS; ANTIVIRAL AGENTS; CELL LINE, TUMOR; CHEMOKINES; CYTOKINES; DRUGS, CHINESE HERBAL; ENTEROVIRUS A, HUMAN; ENTEROVIRUS INFECTIONS; HERPESVIRIDAE INFECTIONS; HERPESVIRUS 1, HUMAN; HUMANS; IMMUNOGLOBULIN G; IMMUNOLOGIC FACTORS; LEUKOCYTES, MONONUCLEAR; MACROPHAGES; MATERIA MEDICA; MICE; MICE, INBRED BALB C; MONOCYTES; NITRIC OXIDE; VIRUS REPLICATION;

EID: 77951244551     PISSN: 0192415X     EISSN: None     Source Type: Journal    
DOI: 10.1142/S0192415X10007749     Document Type: Article

References (41)

1. Ansel, K.M., R.B.S. Harris and J.G. Cyster. CXCL 13 is required for B1 cell homing, natural antibody production, and body cavity immunity. Immunity 16: 67-76, 2002.
2. Bogdan, C., M. Rollinghoff and A. Diefenbach. Reactive oxygen and reactive nitrogen intermediates in innate and specific immunity. Curr. Opin. Immunol. 12: 64-76, 2000.
3. Burbano, R.R., M.F. Leal, J.B. da Costa, O. Bahia Mde, P.D. de Lima, A.S. Khayat, I.C. Selig-man, P.P. de Assumpção, D.F. Buchi and A. Smith Mde. Lymphocyte proliferation stimulated by activated human macrophages treated with Canova. Homeopathy 98: 45-48, 2009.
4. Chen, S.H., H.W. Yao, I.T. Chen, B. Shieh, C. Li and S.H. Chen. Suppression of transcription factor early growth response 1 reduces herpes simplex virus lethality in mice. J. Clin. Invest. 118: 3470-3477, 2008a.
5. Chen, Y.J., C.D. Kuo, Y.M. Tsai, C.C. Yu, G.S. Wang and H.F. Liao. Norcantharidin induces anoikis through Jun-N-terminal kinase activation in CT26 colorectal cancer cells. Anti-Cancer Drug 19: 55-64, 2008b.
6. Chen, Y.Y. and H.M. Chang. Antiproliferative and differentiating effects of polysaccharide fraction from fuling (Poria cocos) on human leukemic U937 and HL-60 cells. Food Chem. Toxicol. 42: 759-769, 2004.
7. Cheng, A., F. Wan, J. Wang, Z. Jin and X. Xu. Macrophage immunomodulatory activity of polysac-charides isolated from Glycyrrhiza uralensis Fish. Int. Immunopharmacol. 8: 43-50, 2008.
8. Cho, W.C. and K.N. Leung. in vitro and in vivo anti-tumor effects of Astragalus membranaceus. Cancer Lett. 252: 43-54, 2007.
9. Chung, W.T., S.H. Lee, J.D. Kim, N.S. Sung, B. Hwang, S.Y. Lee, C.Y. Yu and H.Y. Lee. Effect of the extracts from Glycyrrhiza uralensis Fisch on the growth characteristics of human cell lines: anti-tumor and immune activation activities. Cytotechnology 37: 55-64, 2001.
10. Claek, M.R. IgG effector mechanisms. Chem. Immunol. 65: 88-110, 1997.
11. de Oliveira, C.C., S.M. de Oliveira, V.M. Goes, C.M. Probst, M.A. Krieger and D.F. Buchi. Gene expression profiling of macrophages following mice treatment with an immunomodulator medication. J. Cell. Biochem. 104: 1364-1377, 2008.
12. Du, X.F., C.Z. Jiang, C.F. Wu, E.K. Won and S.Y. Choung. Synergistic immunostimulatory effect of pidotimod and red ginseng acidic polysaccharide on humoral immunity of immunosuppressed mice. Pharmazie 63: 904-908, 2008.
13. Hornebeck, W. Down-regulation of tissue inhibitor of matrix metalloprotease-1 (TIMP-1) in aged human skin contributes to matrix degradation and impaired cell growth and survival. Pathol. Biol. 51: 569-573, 2004.
14. Iida, N. and G.R. Grotendorst. Cloning and sequencing of a new gro transcript from activated human monocytes: expression in leukocytes and wound tissue. Mol. Cell. Biol. 10: 5596-5599, 1990.
15. Kim, S.H., H.N. Jung, K.Y. Lee, J. Kim, J.C. Lee and Y.S. Jang. Suppression of Th2-type immune response-mediated allergic diarrhea following oral administration of traditional Korean medicine: Atractylodes macrocephala Koidz. Immunopharmacol. Immunotoxicol. 27: 331-343, 2005.
16. Ko, H.C., BL. Wei and W.F. Chiou. The effect of medicinal plants used in Chinese folk medicine on RANTES secretion by virus-infected human epithelial cells. J. Ethnopharmacol. 107: 205-210, 2006.
17. Kong, W., Y. Zhao, L. Shan, X. Xiao and W. Guo. Thermochemical studies on the quantity-antibacterial effect relationship of four organic acids from Radix Isatidis on Escherichia coli growth. Biol. Pharm. Bull. 31: 1301-1305, 2008. (Pubitemid 351930636)
18. Kuo, K.K., J.S. Chang, K.C. Wang and L.C. Chiang. Water extract of Glycyrrhiza uralensis inhibited enterovirus 71 in a human foreskin fibroblast cell line. Am. J. Chin. Med. 37: 383-394, 2009.
19. Lee, J.C., K.Y. Lee, YO. Son, K.C. Choi, J. Kim, S.H. Kim, G.H. Chung and Y.S. Jang. Stimulating effects on mouse splenocytes of glycoproteins from the herbal medicine Atractylodes macrocephala Koidz. Phytomedicine 14: 390-395, 2007.
20. Lee, J.H., J.S. Shim, M.S. Chung, S.T. Lim and K.H. Kim. Inhibition of pathogen adhesion to host cells by polysaccharides from Panax ginseng. Biosci. Biotechnol. Biochem. 73: 209-212, 2009.
21. Li, JX. and ZY. Yu. Cimicifugae rhizoma: from origins, bioactive constituents to clinical outcomes. Curr Med. Chem. 13: 2927-2951, 2006.
22. Li, R.J., S.D. Qiu, HX. Chen, H. Tian and HX. Wang. The immunotherapeutic effects of Astragalus polysaccharide in type 1 diabetic mice. Biol. Pharm. Bull. 30: 470-476, 2007.
23. Lim, H.W., D. He, S. Esquenazi-Behar, K.B. Yancey and N.A. Soter. C5a, cutaneous mast cells, and inflammation: in vitro and in vivo studies in a murine model. J. Invest. Dermatol. 97: 305-311, 1991.
24. Lin, T.Y., YC. Liu, J.R. Jheng, H.P. Tsai, J.T. Jan, W.R. Wong and J.T. Horng. Anti-enterovirus 71 activity screening of chinese herbs with anti-infection and inflammation activities. Am. J. Chin. Med. 37: 143-158, 2009.
25. Lopes, L., L.M.F. Godoy, C.C. de Oliveira, J. Gabardo, R. J.G. Schadeck and D.F. Buchi. Phagocytosis, endosomal/lysosomal system and other cellular aspects of macrophage activation by Canova medication. Micron 37: 277-287, 2006.
26. Luster, A.D. The role of chemokines in linking innate and adaptive immunity. Curr. Opin. Immunol. 14: 129-135, 2002.
27. Mariotti, S., V. Sargentini, C. Marcantonio, E. Todero, R. Teloni, M.C. Gagliardi, A.R. Ciccaglione and R. Nisini. T-cell-mediated and antigen-dependent differentiation of human monocyte into different dendritic cell subsets: a feedback control of Th1/Th2 responses. FASEB J. 22: 3370-3379, 2008.
28. Mendez, M.P., S.B. Morris, S. Wilcoxen, E. Greeson, B. Moore and R. Paine 3rd. Shedding of soluble ICAM-1 into the alveolar space in murine models of acute lung injury. Am. J. Physiol. Lung Cell Mol. Physiol. 290: L962-970, 2006.
29. Metcalf, D. The granulocyte-macrophage colony-stimulating factors. Science 229: 16-22, 1985.
30. Pelus, L.M. and S. Fukuda. Peripheral blood stem cell mobilization: the CXCR2 ligand GRObeta rapidly mobilizes hematopoietic stem cells with enhanced engraftment properties. Exp. Hematol 34: 1010-1020, 2006.
31. Piemonte, M.R. and D.F. Buchi. Analysis of IL-2, INF-γ and TNF-α production, α5β1 integrins and actin filaments distribution in peritoneal mouse macrophages treated with homeopathic medicament. J. Submicrosc. Cytol. Pathol. 34: 255-263, 2002.
32. Re, F. and J.L. Strominger. Toll-like receptor 2 (TLR2) and TLR4 differentially activate human dendritic cells. J. Biol. Chem. 276: 37692-37699, 2001.
33. Rollins, B.J., A. Walz and M. Baggiolini. Recombinant human MCP-1/JE induces chemotaxis, calcium flux, and the respiratory burst in human monocytes. Blood 78: 1112-1116, 1991.
34. Seligmann, I.C., P.D. Lima, P.C. Cardoso, A.S. Khayat, M.O. Bahia, F. Buchi Dde, I.R. Cabral and R.R. Burbano. The anticancer homeopathic composite "Canova Method" is not genotoxic for human lymphocytes in vitro. Genet. Mol. Res. 2: 223-228, 2003.
35. Sweet, M.J. and D.A. Hume. CSF-1 as a regulator of macrophage activation and immune responses. Arch. Immunol. Ther. Exp. (Warsz.) 51: 169-177, 2004.
36. Takahachi, G., M.L.F. Maluf, T.I.E. Svidzinski, M.M.O. Dalalio, C.A. Bersani-Amado and R.K.N. Cuman. In vivo and in vitro effects of the Canova medicine on experimental infection with Paracoccidioides brasiliensis in mice. Indian J. Pharmacol. 38: 350-354, 2006.
37. Wang, C.K., M.L. Colgrave, K.R. Gustafson, D.C. Ireland, U. Goransson and D.J. Craik. Anti-HIV cyclotides from the Chinese medicinal herb Viola yedoensis. J. Nat. Prod. 71: 47-52, 2008.
38. Wen, Y.Y., T.Y. Chang, S.T. Chen, C. Li and H.S. Liu. Comparative study of enterovirus 71 infection of human cell line. J. Med. Virol. 70: 109-118, 2003.
39. Xie, C., T. Kokubun, P.J. Houghton and M.S. Simmonds. Antibacterial activity of the Chinese traditional medicine, Zi-Hua-Di-Ding. Phytother. Res. 18: 497-500, 2004.
40. Xue, J., Y. Xu, L. Jin, G. Liu, Y. Sun, S. Li and J. Zhang. Effects of traditional Chinese medicine on immune responses in abalone, Haliotis discus hannai Ino. Fish Shellfish Immunol. 24: 752-758, 2008.
41. Zhao, Y.L., J.B. Wang, L.M. Shan, C. Jin, L. Ma and X.H. Xiao. Effect of Radix isatidis polysaccharides on immunological function and expression of immune related cytokines in mice. Chin. J. Integr. Med. 14: 207-211, 2008.