Rab25 increases cellular ATP and glycogen stores protecting cancer cells from bioenergetic stress

EMBO Molecular Medicine

Volumn 4, Issue 2, 2012, Pages 125-141

  Cheng, Kwai Wa ^a   Agarwal, Roshan ^a,b   Mitra, Shreya ^a   Lee, Ju Seog ^a   Carey, Mark ^a,c   Gray, Joe W ^d   Mills, Gordon B ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^d LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

Author keywords

AKT; Bioenergetic; Cell death; Glycogen; Rab25

Indexed keywords

ADENOSINE TRIPHOSPHATE; GLUCOSE; GLYCOGEN; GUANOSINE TRIPHOSPHATASE; PROTEIN KINASE B; RAB25 PROTEIN; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; AUTOPHAGY; CANCER CELL; CANCER CELL CULTURE; CELL LEVEL; CELL PROTECTION; CELL SURVIVAL; CELLULAR STRESS RESPONSE; CONTROLLED STUDY; DIET RESTRICTION; ENZYME ACTIVATION; ENZYME BINDING; EPITHELIUM CELL; FEMALE; GENE EXPRESSION PROFILING; GLUCOSE TRANSPORT; GLYCOGEN METABOLISM; HUMAN; HUMAN CELL; NUTRIENT AVAILABILITY; OVARY CANCER; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION;

ADENOSINE TRIPHOSPHATE; APOPTOSIS; AUTOPHAGY; CELL DEATH; ENERGY METABOLISM; GLYCOGEN; HUMANS; NEOPLASMS; RAB GTP-BINDING PROTEINS; TUMOR CELLS, CULTURED;

EID: 84863033816     PISSN: 17574676     EISSN: 17574684     Source Type: Journal    
DOI: 10.1002/emmm.201100193     Document Type: Article

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