Glucocorticoid-dependent phosphorylation of the transcriptional coregulator GRIP1

Molecular and Cellular Biology

Volumn 32, Issue 4, 2012, Pages 730-739

  Dobrovolna, Jana ^a   Chinenov, Yurii ^a   Kennedy, Megan A ^a   Liu, Bill ^a   Rogatsky, Inez ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASEIN KINASE II; CYCLIN DEPENDENT KINASE 9; GLUCOCORTICOID; NUCLEAR RECEPTOR COACTIVATOR 2;

ARTICLE; CELL SPECIFICITY; CONTROLLED STUDY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOPRECIPITATION; IN VIVO STUDY; MUTAGENESIS; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BINDING SITES; CASEIN KINASE II; CELL LINE; CYCLIN-DEPENDENT KINASE 9; DNA PRIMERS; GLUCOCORTICOIDS; HUMANS; MICE; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; NUCLEAR RECEPTOR COACTIVATOR 2; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; RATS; RECEPTORS, GLUCOCORTICOID; SEQUENCE HOMOLOGY, AMINO ACID; TRANSCRIPTIONAL ACTIVATION;

EID: 84863032295     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.06473-11     Document Type: Article

References (44)

1. Amazit L, et al. 2007. Regulation of SRC-3 intercompartmental dynamics by estrogen receptor and phosphorylation. Mol. Cell. Biol. 27:6913- 6932.
2. Barnes PJ. 2010. Mechanisms and resistance in glucocorticoid control of inflammation. J. Steroid Biochem. Mol. Biol. 120:76-85.
3. Baumann CT, et al. 2001. The glucocorticoid receptor interacting protein 1 (GRIP1) localizes in discrete nuclear foci that associate with ND10 bodies and are enriched in components of the 26S proteasome. Mol. Endocrinol. 15:485-500.
4. Belandia B, Orford RL, Hurst HC, Parker MG. 2002. Targeting of SWI/SNF chromatin remodelling complexes to estrogen-responsive genes. EMBO J. 21:4094-4103.
5. Bhandare R, et al. 2010. Glucocorticoid receptor interacting protein-1 restores glucocorticoid responsiveness in steroid-resistant airway structural cells. Am. J. Respir. Cell Mol. Biol. 42:9 -15.
6. Bledsoe RK, et al. 2002. Crystal structure of the glucocorticoid receptor ligand binding domain reveals a novel mode of receptor dimerization and coactivator recognition. Cell 110:93-105.
7. Chen D, et al. 1999. Regulation of transcription by a protein methyltransferase. Science 284:2174 -2177.
8. Chen W, Rogatsky I, Garabedian MJ. 2006. MED14 and MED1 differentially regulate target-specific gene activation by the glucocorticoid receptor. Mol. Endocrinol. 20:560 -572.
9. Chen YH, Kim JH, Stallcup MR. 2005. GAC63, a GRIP1-dependent nuclear receptor coactivator. Mol. Cell. Biol. 25:5965-5972.
10. Darimont BD, et al. 1998. Structure and specificity of nuclear receptorcoactivator interactions. Genes Dev. 12:3343-3356.
11. Flammer JR, et al. 2010. The type I interferon signaling pathway is a target for glucocorticoid inhibition. Mol. Cell. Biol. 30:4564-4574.
12. Frigo DE, et al. 2006. p38 mitogen-activated protein kinase stimulates estrogen-mediated transcription and proliferation through the phosphorylation and potentiation of the p160 coactivator glucocorticoid receptorinteracting protein 1. Mol. Endocrinol. 20:971-983.
13. Gregory CW, et al. 2004. Epidermal growth factor increases coactivation of the androgen receptor in recurrent prostate cancer. J. Biol. Chem. 279: 7119-7130.
14. Gronemeyer H, Gustafsson JA, Laudet V. 2004. Principles for modulation of the nuclear receptor superfamily. Nat. Rev. Drug Discov. 3:950- 964.
15. Heery DM, Kalkhoven E, Hoare S, Parker MG. 1997. A signature motif in transcriptional co-activators mediates binding to nuclear receptors. Nature 387:733-736.
16. Hittelman AB, Burakov D, Iniguez-Lluhi JA, Freedman LP, Garabedian MJ. 1999. Differential regulation of glucocorticoid receptor transcriptional activation via AF-1-associated proteins. EMBO J. 18:5380 -5388.
17. Hoang T, et al. 2004. cAMP-dependent protein kinase regulates ubiquitin-proteasome-mediated degradation and subcellular localization of the nuclear receptor coactivator GRIP1. J. Biol. Chem. 279:49120- 49130.
18. Hong H, Kohli K, Garabedian MJ, Stallcup MR. 1997. GRIP1, a transcriptional coactivator for the AF-2 transactivation domain of steroid, thyroid, retinoid, and vitamin D receptors. Mol. Cell. Biol. 17:2735-2744.
19. Jeong JW, et al. 2006. The genomic analysis of the impact of steroid receptor coactivators ablation on hepatic metabolism. Mol. Endocrinol. 20:1138 -1152.
20. Johnson PR, et al. 2001. Airway smooth muscle cell proliferation is increased in asthma. Am. J. Respir. Crit. Care Med. 164:474-477.
21. Kim JH, Li H, Stallcup MR. 2003. CoCoA, a nuclear receptor coactivator which acts through an N-terminal activation domain of p160 coactivators. Mol. Cell 12:1537-1549.
22. Lee YH, Campbell HD, Stallcup MR. 2004. Developmentally essential protein flightless I is a nuclear receptor coactivator with actin binding activity. Mol. Cell. Biol. 24:2103-2117.
23. Lee YH, Coonrod SA, Kraus WL, Jelinek MA, Stallcup MR. 2005. Regulation of coactivator complex assembly and function by protein arginine methylation and demethylimination. Proc. Natl. Acad. Sci. U. S. A. 102:3611-3616.
24. Lee YH, Koh SS, Zhang X, Cheng X, Stallcup MR. 2002. Synergy among nuclear receptor coactivators: selective requirement for protein methyltransferase and acetyltransferase activities. Mol. Cell. Biol. 22:3621-3632.
25. Lefstin JA, Yamamoto KR. 1998. Allosteric effects of DNA on transcriptional regulators. Nature 392:885- 888.
26. Li C, et al. 2007. Specific amino acid residues in the basic helix-loop-helix domain of SRC-3 are essential for its nuclear localization and proteasomedependent turnover. Mol. Cell. Biol. 27:1296 -1308.
27. Lopez GN, Turck CW, Schaufele F, Stallcup MR, Kushner PJ. 2001. Growth factors signal to steroid receptors through mitogen-activated protein kinase regulation of p160 coactivator activity. J. Biol. Chem. 276: 22177-22182.
28. McKenna NJ, et al. 2009. Minireview: evolution of NURSA, the Nuclear Receptor Signaling Atlas. Mol. Endocrinol. 23:740 -746.
29. Nolte RT, et al. 1998. Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-g. Nature 395:137-143.
30. Reddy TE, et al. 2009. Genomic determination of the glucocorticoid response reveals unexpected mechanisms of gene regulation. Genome Res. 19:2163-2171.
31. Reily MM, Pantoja C, Hu X, Chinenov Y, Rogatsky I. 2006. The GRIP1:IRF3 interaction as a target for glucocorticoid receptor-mediated immunosuppression. EMBO J. 25:108 -117.
32. Rogatsky I, Luecke HF, Leitman DC, Yamamoto KR. 2002. Alternate surfaces of transcriptional coregulator GRIP1 function in different glucocorticoid receptor activation and repression contexts. Proc. Natl. Acad. Sci. U. S. A. 99:16701-16706.
33. Rogatsky I, Trowbridge JM, Garabedian MJ. 1997. Glucocorticoid receptor-mediated cell cycle arrest is achieved through distinct cellspecific transcriptional regulatory mechanisms. Mol. Cell. Biol. 17:3181- 3193.
34. Rogatsky I, et al. 2003. Target-specific utilization of transcriptional regulatory surfaces by the glucocorticoid receptor. Proc. Natl. Acad. Sci. U. S. A. 100:13845-13850.
35. Rogatsky I, Zarember KA, Yamamoto KR. 2001. Factor recruitment and TIF2/GRIP1 corepressor activity at a collagenase-3 response element that mediates regulation by phorbol esters and hormones. EMBO J. 20:6071- 6083.
36. So AY, Chaivorapol C, Bolton EC, Li H, Yamamoto KR. 2007. Determinants of cell- and gene-specific transcriptional regulation by the glucocorticoid receptor. PLoS Genet. 3:e94.
37. Surjit M, et al. 2011. Widespread negative response elements mediate direct repression by agonist-liganded glucocorticoid receptor. Cell 145: 224-241.
38. Tsai MJ, O'Malley BW. 1994. Molecular mechanisms of action of steroid/thyroid receptor superfamily members. Annu. Rev. Biochem. 63:451- 486.
39. Vaquerizas JM, Kummerfeld SK, Teichmann SA, Luscombe NM. 2009. A census of human transcription factors: function, expression and evolution. Nat. Rev. Genet. 10:252-263.
40. Voegel JJ, et al. 1998. The coactivator TIF2 contains three nuclear receptor-binding motifs and mediates transactivation through CBP binding-dependent and -independent pathways. EMBO J. 17:507-519.
41. Wang JC, et al. 2004. Chromatin immunoprecipitation (ChIP) scanning identifies primary glucocorticoid receptor target genes. Proc. Natl. Acad. Sci. U. S. A. 101:15603-15608.
42. Wu RC, Feng Q, Lonard DM, O'Malley BW. 2007. SRC-3 coactivator functional lifetime is regulated by a phospho-dependent ubiquitin time clock. Cell 129:1125-1140.
43. Xu J, Wu RC, O'Malley BW. 2009. Normal and cancer-related functions of the p160 steroid receptor co-activator (SRC) family. Nat. Rev. Cancer 9:615- 630.
44. Yan F, Gao X, Lonard DM, Nawaz Z. 2003. Specific ubiquitinconjugating enzymes promote degradation of specific nuclear receptor coactivators. Mol. Endocrinol. 17:1315-1331.