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Volumn 108, Issue , 2012, Pages 303-316

Genome-Wide Screens for Gene Products Regulating Lipid Droplet Dynamics

Author keywords

Choline; Fibroblast; Mobilization; Sterol; Storage; Synthesis

Indexed keywords


EID: 84863020848     PISSN: 0091679X     EISSN: None     Source Type: Book Series    
DOI: 10.1016/B978-0-12-386487-1.00014-6     Document Type: Chapter
Times cited : (9)

References (51)
  • 1
    • 0032911957 scopus 로고    scopus 로고
    • Mechanisms of lipid-body formation
    • Murphy D.J., Vance J. Mechanisms of lipid-body formation. Trends Biochem. Sci. 1999, 24:109-115.
    • (1999) Trends Biochem. Sci. , vol.24 , pp. 109-115
    • Murphy, D.J.1    Vance, J.2
  • 2
    • 33646168160 scopus 로고    scopus 로고
    • Lipid droplets: a unified view of a dynamic organelle
    • Martin S., Parton R.G. Lipid droplets: a unified view of a dynamic organelle. Nat. Rev. Mol. Cell Biol. 2006, 7:373-378.
    • (2006) Nat. Rev. Mol. Cell Biol. , vol.7 , pp. 373-378
    • Martin, S.1    Parton, R.G.2
  • 3
    • 34547216748 scopus 로고    scopus 로고
    • A lipid-based model for the creation of an escape hatch from the endoplasmic reticulum
    • Ploegh H.L. A lipid-based model for the creation of an escape hatch from the endoplasmic reticulum. Nature 2007, 448:435-438.
    • (2007) Nature , vol.448 , pp. 435-438
    • Ploegh, H.L.1
  • 4
    • 33751161853 scopus 로고    scopus 로고
    • Adipophilin-enriched domains in the ER membrane are sites of lipid droplet biogenesis
    • Robenek H., Hofnagel O., Buers I., Robenek M.J., Troyer D., Severs N.J. Adipophilin-enriched domains in the ER membrane are sites of lipid droplet biogenesis. J. Cell Sci. 2006, 119:4215-4224.
    • (2006) J. Cell Sci. , vol.119 , pp. 4215-4224
    • Robenek, H.1    Hofnagel, O.2    Buers, I.3    Robenek, M.J.4    Troyer, D.5    Severs, N.J.6
  • 6
    • 67349209504 scopus 로고    scopus 로고
    • Biogenesis of cytoplasmic lipid droplets: from the lipid ester globule in the membrane to the visible structure
    • Ohsaki Y., Cheng J., Suzuki M., Shinohara Y., Fujita A., Fujimoto T. Biogenesis of cytoplasmic lipid droplets: from the lipid ester globule in the membrane to the visible structure. Biochim. Biophys. Acta 2009, 1791:399-407.
    • (2009) Biochim. Biophys. Acta , vol.1791 , pp. 399-407
    • Ohsaki, Y.1    Cheng, J.2    Suzuki, M.3    Shinohara, Y.4    Fujita, A.5    Fujimoto, T.6
  • 11
    • 0016818790 scopus 로고
    • Yeast sterol esters and their relationship to the growth of yeast
    • Bailey R.B., Parks L.W. Yeast sterol esters and their relationship to the growth of yeast. J. Bacteriol. 1975, 124:606-612.
    • (1975) J. Bacteriol. , vol.124 , pp. 606-612
    • Bailey, R.B.1    Parks, L.W.2
  • 12
    • 0018651858 scopus 로고
    • Triaglycerol metabolism in Saccharomyces cerevisiae. Relation to phospholipid synthesis
    • Taylor F.R., Parks L.W. Triaglycerol metabolism in Saccharomyces cerevisiae. Relation to phospholipid synthesis. Biochim. Biophys. Acta 1979, 575:204-214.
    • (1979) Biochim. Biophys. Acta , vol.575 , pp. 204-214
    • Taylor, F.R.1    Parks, L.W.2
  • 13
    • 0018123233 scopus 로고
    • Metabolic interconversion of free sterols and steryl esters in Saccharomyces cerevisiae
    • Taylor F.R., Parks L.W. Metabolic interconversion of free sterols and steryl esters in Saccharomyces cerevisiae. J. Bacteriol. 1978, 136:531-537.
    • (1978) J. Bacteriol. , vol.136 , pp. 531-537
    • Taylor, F.R.1    Parks, L.W.2
  • 14
    • 58149308056 scopus 로고    scopus 로고
    • Cdk1/Cdc28-dependent activation of the major triacylglycerol lipase Tgl4 in yeast links lipolysis to cell-cycle progression
    • Kurat C.F., Wolinski H., Petschnigg J., Kaluarachchi S., Andrews B., Natter K., Kohlwein S.D. Cdk1/Cdc28-dependent activation of the major triacylglycerol lipase Tgl4 in yeast links lipolysis to cell-cycle progression. Mol. Cell 2009, 33:53-63.
    • (2009) Mol. Cell , vol.33 , pp. 53-63
    • Kurat, C.F.1    Wolinski, H.2    Petschnigg, J.3    Kaluarachchi, S.4    Andrews, B.5    Natter, K.6    Kohlwein, S.D.7
  • 15
    • 71449102613 scopus 로고    scopus 로고
    • Good fat, essential cellular requirements for triacylglycerol synthesis to maintain membrane homeostasis in yeast
    • Petschnigg J., Wolinski H., Kolb D., Zellnig G., Kurat C.F., Natter K., Kohlwein S.D. Good fat, essential cellular requirements for triacylglycerol synthesis to maintain membrane homeostasis in yeast. J. Biol. Chem. 2009, 284:30981-30993.
    • (2009) J. Biol. Chem. , vol.284 , pp. 30981-30993
    • Petschnigg, J.1    Wolinski, H.2    Kolb, D.3    Zellnig, G.4    Kurat, C.F.5    Natter, K.6    Kohlwein, S.D.7
  • 17
    • 0030957823 scopus 로고    scopus 로고
    • Molecular basis for membrane phospholipid diversity:why are there so many lipids?
    • Dowhan W. Molecular basis for membrane phospholipid diversity:why are there so many lipids?. Ann. Rev. Biochem. 1997, 66:199-232.
    • (1997) Ann. Rev. Biochem. , vol.66 , pp. 199-232
    • Dowhan, W.1
  • 18
    • 0021770019 scopus 로고
    • Regulatory role of phosphatidate phosphatase in triacylglycerol synthesis of Saccharomyces cerevisiae
    • Hosaka K., Yamashita S. Regulatory role of phosphatidate phosphatase in triacylglycerol synthesis of Saccharomyces cerevisiae. Biochim. Biophys. Acta 1984, 796:110-117.
    • (1984) Biochim. Biophys. Acta , vol.796 , pp. 110-117
    • Hosaka, K.1    Yamashita, S.2
  • 19
    • 0033214479 scopus 로고    scopus 로고
    • Characterization and function in vivo of two novel phospholipases B/lysophospholipases from Saccharomyces cerevisiae
    • Merkel O., Fido M., Mayr J.A., Pruger H., Raab F., Zandonella G., Kohlwein S.D., Paltauf F. Characterization and function in vivo of two novel phospholipases B/lysophospholipases from Saccharomyces cerevisiae. J. Biol. Chem. 1999, 274:28121-28127.
    • (1999) J. Biol. Chem. , vol.274 , pp. 28121-28127
    • Merkel, O.1    Fido, M.2    Mayr, J.A.3    Pruger, H.4    Raab, F.5    Zandonella, G.6    Kohlwein, S.D.7    Paltauf, F.8
  • 20
    • 33947200308 scopus 로고    scopus 로고
    • Phosphatidylcholine synthesis and its catabolism by yeast neuropathy target esterase 1
    • Fernandez-Murray J.P., McMaster C.R. Phosphatidylcholine synthesis and its catabolism by yeast neuropathy target esterase 1. Biochim. Biophys. Acta 2007, 1771:331-336.
    • (2007) Biochim. Biophys. Acta , vol.1771 , pp. 331-336
    • Fernandez-Murray, J.P.1    McMaster, C.R.2
  • 22
    • 78651385047 scopus 로고    scopus 로고
    • DGK1-encoded diacylglycerol kinase activity is required for phospholipid synthesis during growth resumption from stationary phase in Saccharomyces cerevisiae
    • Fakas S., Konstantinou C., Carman G.M. DGK1-encoded diacylglycerol kinase activity is required for phospholipid synthesis during growth resumption from stationary phase in Saccharomyces cerevisiae. J. Biol. Chem. 2011, 286:1464-1474.
    • (2011) J. Biol. Chem. , vol.286 , pp. 1464-1474
    • Fakas, S.1    Konstantinou, C.2    Carman, G.M.3
  • 23
    • 0027231368 scopus 로고
    • Sterol composition of yeast organelle membranes and subcellular distribution of enzymes involved in sterol metabolism
    • Zinser E., Paltauf F., Daum G. Sterol composition of yeast organelle membranes and subcellular distribution of enzymes involved in sterol metabolism. J. Bacteriol. 1993, 175:2853-2858.
    • (1993) J. Bacteriol. , vol.175 , pp. 2853-2858
    • Zinser, E.1    Paltauf, F.2    Daum, G.3
  • 24
    • 59049107663 scopus 로고    scopus 로고
    • Mobilization of steryl esters from lipid particles of the yeast Saccharomyces cerevisiae
    • Wagner A., Grillitsch K., Leitner E., Daum G. Mobilization of steryl esters from lipid particles of the yeast Saccharomyces cerevisiae. Biochim. Biophys. Acta 2009, 1791:118-124.
    • (2009) Biochim. Biophys. Acta , vol.1791 , pp. 118-124
    • Wagner, A.1    Grillitsch, K.2    Leitner, E.3    Daum, G.4
  • 26
    • 0029835340 scopus 로고    scopus 로고
    • Molecular cloning and characterization of two isoforms of Saccharomyces cerevisiae acyl-CoA:sterol acyltransferase
    • Yu C., Kennedy N.J., Chang C.C., Rothblatt J.A. Molecular cloning and characterization of two isoforms of Saccharomyces cerevisiae acyl-CoA:sterol acyltransferase. J. Biol. Chem. 1996, 271:24157-24163.
    • (1996) J. Biol. Chem. , vol.271 , pp. 24157-24163
    • Yu, C.1    Kennedy, N.J.2    Chang, C.C.3    Rothblatt, J.A.4
  • 27
    • 0034612345 scopus 로고    scopus 로고
    • Phospholipid:diacylglycerol acyltransferase: an enzyme that catalyzes the acyl-CoA-independent formation of triacylglycerol in yeast and plants
    • Dahlqvist A., Stahl U., Lenman M., Banas A., Lee M., Sandager L., Ronne H., Stymne S. Phospholipid:diacylglycerol acyltransferase: an enzyme that catalyzes the acyl-CoA-independent formation of triacylglycerol in yeast and plants. Proc. Natl. Acad. Sci. U. S. A. 2000, 97:6487-6492.
    • (2000) Proc. Natl. Acad. Sci. U. S. A. , vol.97 , pp. 6487-6492
    • Dahlqvist, A.1    Stahl, U.2    Lenman, M.3    Banas, A.4    Lee, M.5    Sandager, L.6    Ronne, H.7    Stymne, S.8
  • 28
    • 0036135597 scopus 로고    scopus 로고
    • Synthesis of triacylglycerols by the acyl-coenzyme A:diacyl-glycerol acyltransferase Dga1p in lipid particles of the yeast Saccharomyces cerevisiae
    • Sorger D., Daum G. Synthesis of triacylglycerols by the acyl-coenzyme A:diacyl-glycerol acyltransferase Dga1p in lipid particles of the yeast Saccharomyces cerevisiae. J. Bacteriol. 2002, 184:519-524.
    • (2002) J. Bacteriol. , vol.184 , pp. 519-524
    • Sorger, D.1    Daum, G.2
  • 29
  • 30
    • 0033974053 scopus 로고    scopus 로고
    • Contribution of Are1p and Are2p to steryl ester synthesis in the yeast Saccharomyces cerevisiae
    • Zweytick D., Leitner E., Kohlwein S.D., Yu C., Rothblatt J., Daum G. Contribution of Are1p and Are2p to steryl ester synthesis in the yeast Saccharomyces cerevisiae. Eur. J. Biochem. 2000, 267:1075-1082.
    • (2000) Eur. J. Biochem. , vol.267 , pp. 1075-1082
    • Zweytick, D.1    Leitner, E.2    Kohlwein, S.D.3    Yu, C.4    Rothblatt, J.5    Daum, G.6
  • 31
    • 0038182336 scopus 로고    scopus 로고
    • Triacylglycerol biosynthesis in yeast
    • Sorger D., Daum G. Triacylglycerol biosynthesis in yeast. Appl Microbiol. Biotechnol. 2003, 61:289-299.
    • (2003) Appl Microbiol. Biotechnol. , vol.61 , pp. 289-299
    • Sorger, D.1    Daum, G.2
  • 32
    • 0037931415 scopus 로고    scopus 로고
    • YMR313c/TGL3 encodes a novel triacylglycerol lipase located in lipid particles of Saccharomyces cerevisiae
    • Athenstaedt K., Daum G. YMR313c/TGL3 encodes a novel triacylglycerol lipase located in lipid particles of Saccharomyces cerevisiae. J. Biol. Chem. 2003, 278:23317-23323.
    • (2003) J. Biol. Chem. , vol.278 , pp. 23317-23323
    • Athenstaedt, K.1    Daum, G.2
  • 33
    • 27844486104 scopus 로고    scopus 로고
    • Tgl4p and Tgl5p, two triacylglycerol lipases of the yeast Saccharomyces cerevisiae are localized to lipid particles
    • Athenstaedt K., Daum G. Tgl4p and Tgl5p, two triacylglycerol lipases of the yeast Saccharomyces cerevisiae are localized to lipid particles. J. Biol. Chem. 2005, 280:37301-37309.
    • (2005) J. Biol. Chem. , vol.280 , pp. 37301-37309
    • Athenstaedt, K.1    Daum, G.2
  • 35
    • 14044272811 scopus 로고    scopus 로고
    • The Saccharomyces cerevisiae YLL012/YEH1, YLR020/YEH2, and TGL1 genes encode a novel family of membrane-anchored lipases that are required for steryl ester hydrolysis
    • Koffel R., Tiwari R., Falquet L., Schneiter R. The Saccharomyces cerevisiae YLL012/YEH1, YLR020/YEH2, and TGL1 genes encode a novel family of membrane-anchored lipases that are required for steryl ester hydrolysis. Mol. Cell Biol. 2005, 25:1655-1668.
    • (2005) Mol. Cell Biol. , vol.25 , pp. 1655-1668
    • Koffel, R.1    Tiwari, R.2    Falquet, L.3    Schneiter, R.4
  • 36
    • 17144404154 scopus 로고    scopus 로고
    • YEH2/YLR020c encodes a novel steryl ester hydrolase of the yeast Saccharomyces cerevisiae
    • Mullner H., Deutsch G., Leitner E., Ingolic E., Daum G. YEH2/YLR020c encodes a novel steryl ester hydrolase of the yeast Saccharomyces cerevisiae. J. Biol. Chem. 2005, 280:13321-13328.
    • (2005) J. Biol. Chem. , vol.280 , pp. 13321-13328
    • Mullner, H.1    Deutsch, G.2    Leitner, E.3    Ingolic, E.4    Daum, G.5
  • 40
    • 79958817996 scopus 로고    scopus 로고
    • Seipin, adipogenesis and lipid droplets
    • Fei W., Du X., Yang H. Seipin, adipogenesis and lipid droplets. Trends Endocrinol. Metab. 2011, 22:204-210.
    • (2011) Trends Endocrinol. Metab. , vol.22 , pp. 204-210
    • Fei, W.1    Du, X.2    Yang, H.3
  • 41
    • 79955629359 scopus 로고    scopus 로고
    • Tissue-Autonomous Function of Drosophila Seipin in Preventing Ectopic Lipid Droplet Formation
    • Tian Y., Bi J., Shui G., Liu Z., Xiang Y., Liu Y., Wenk M.R., Yang H., Huang X. Tissue-Autonomous Function of Drosophila Seipin in Preventing Ectopic Lipid Droplet Formation. PLoS Genet. 2011, 7:e1001364.
    • (2011) PLoS Genet. , vol.7
    • Tian, Y.1    Bi, J.2    Shui, G.3    Liu, Z.4    Xiang, Y.5    Liu, Y.6    Wenk, M.R.7    Yang, H.8    Huang, X.9
  • 45
    • 70350700684 scopus 로고    scopus 로고
    • Conditions of endoplasmic reticulum stress stimulate lipid droplet formation in Saccharomyces cerevisiae
    • Fei W., Wang H., Fu X., Bielby C., Yang H. Conditions of endoplasmic reticulum stress stimulate lipid droplet formation in Saccharomyces cerevisiae. Biochem. J. 2009, 424:61-67.
    • (2009) Biochem. J. , vol.424 , pp. 61-67
    • Fei, W.1    Wang, H.2    Fu, X.3    Bielby, C.4    Yang, H.5
  • 46
    • 54449092523 scopus 로고    scopus 로고
    • A block in endoplasmic reticulum-to-Golgi trafficking inhibits phospholipid synthesis and induces neutral lipid accumulation
    • Gaspar M.L., Jesch S.A., Viswanatha R., Antosh A.L., Brown W.J., Kohlwein S.D., Henry S.A. A block in endoplasmic reticulum-to-Golgi trafficking inhibits phospholipid synthesis and induces neutral lipid accumulation. J. Biol. Chem. 2008, 283:25735-25751.
    • (2008) J. Biol. Chem. , vol.283 , pp. 25735-25751
    • Gaspar, M.L.1    Jesch, S.A.2    Viswanatha, R.3    Antosh, A.L.4    Brown, W.J.5    Kohlwein, S.D.6    Henry, S.A.7
  • 51
    • 70449769682 scopus 로고    scopus 로고
    • Lipid droplets finally get a little R-E-S-P-E-C-T
    • Farese R.V., Walther T.C. Lipid droplets finally get a little R-E-S-P-E-C-T. Cell 2009, 139:855-860.
    • (2009) Cell , vol.139 , pp. 855-860
    • Farese, R.V.1    Walther, T.C.2


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