Protective effects of curcumin against human immunodeficiency virus 1 gp120 V3 loop-induced neuronal injury in rats

Neural Regeneration Research

Volumn 7, Issue 3, 2012, Pages 171-175

  Gong, Zheng ^a,b   Yang, Lijuan ^a,b   Tang, Hongmei ^a,b   Pan, Rui ^a   Xie, Sai ^a,b   Guo, Luyan ^a,b   Wang, Junbin ^a,b   Deng, Qinyin ^a,b   Xiong, Guoyin ^a,b   Xing, Yanyan ^a,b   Dong, Jun ^a,b  

^a MEDICAL COLLEGE OF JINAN UNIVERSITY   (China)

^b JINAN UNIVERSITY   (China)

Author keywords

Caspase 3; Curcumin; gp120 V3 loop; Hippocampal neurons; Human immunodeficiency virus associated neurocognitive function; Mitochondrial membrane potential; Neural regeneration

Indexed keywords

CASPASE 3; CURCUMIN; MESSENGER RNA;

ANIMAL CELL; APOPTOSIS; ARTICLE; CASPASE 3 GENE; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; DRUG STRUCTURE; ENZYME ACTIVATION; GENE; GENE EXPRESSION REGULATION; IN VITRO STUDY; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL TOXICITY; NERVE CELL LESION; NEUROPROTECTION; NEWBORN; NONHUMAN; RAT;

EID: 84863017453     PISSN: 16735374     EISSN: 18767958     Source Type: Journal    
DOI: 10.3969/j.issn.1673-5374.2012.03.002     Document Type: Article

References (28)

1. Buckner CM, Calderon TM, Willams DW, et al. Characterization of monocyte maturation/differentiation that facilitates their transmigration across the blood-brain barrier and infection by HIV: implications for NeuroAIDS. Cell Immunol. 2011;267(2):109-123.
2. Woods SP, Moore DJ, Weber E, et al. Cognitive neuropsychology of HIV-associated neurocognitive disorders. Neuropsychol Rev. 2009;19(2):152-168.
3. Nath A. Human immunodeficiency virus (HIV) proteins in neuropathogenesis of HIV dementia. J Infect Dis. 2002;186 Suppl 2:S193-198.
4. Albright AV, Soldan SS, Gonzalez-Scarano F. Pathogenesis of human immunodeficiency virus-induced neurological disease. J Neurovirol. 2003;9(2):222-227.
5. Alirezaei M, Watry DD, Flynn CF, et al. Human immunodeficiency virus-1/surface glycoprotein 120 induces apoptosis through RNA-activated protein kinase signaling in neurons. J Neurosci. 2007;27(41):11047-11055.
6. Bhaskaran K, Mussini C, Antinori A, et al. Changes in the incidence and predictors of human immunodeficiency virus-associated dementia in the era of highly active antiretroviral therapy. Ann Neurol. 2008;63(2):213-221.
7. Moulignier A. Dementia complex due to HIV disease and aging. Psychol Neuropsychiatr Vieil. 2007;5(3):193-207.
8. Sandur SK, Pandey MK, Sung B, et al. Curcumin, demethoxycurcumin, bisdemethoxycurcumin, tetrahydrocurcumin and turmerones differentially regulate anti-inflammatory and anti-proliferative responses through a ROS-independent mechanism. Carcinogenesis. 2007;28(8):1765-1773.
9. Naik SR, Thakare VN, Patil SR. Protective effect of curcumin on experimentally induced inflammation, hepatotoxicity and cardiotoxicity in rats: evidence of its antioxidant property. Exp Toxicol Pathol. 2011;63(5):419-431.
10. Manikandan P, Sumitra M, Aishwarya S, et al. Curcumin modulates free radical quenching in myocardial ischaemia in rats. Int J Biochem Cell Biol. 2004;36(10):1967-1980.
11. Tang H, Lu D, Pan R, et al. Curcumin improves spatial memory impairment induced by human immunodeficiency virus type 1 glycoprotein 120 V3 loop peptide in rats. Life Sci. 2009;85(1-2): 1-10.
12. Lin MT, Beal MF. Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases. Nature. 2006;443(7113):787-795.
13. Lindl KA, Marks DR, Kolson DL, et al. HIV-associated neurocognitive disorder: pathogenesis and therapeutic opportunities. J Neuroimmune Pharmacol. 2010;5(3):294-309.
14. Lauritzen KH, Moldestad O, Eide L, et al. Mitochondrial DNA toxicity in forebrain neurons causes apoptosis, neurodegeneration, and impaired behavior. Mol Cell Biol. 2010;30(6):1357-1367.
15. Srikanth CV, Wall DM, Maldonado-Contreras A, et al. Salmonella pathogenesis and processing of secreted effectors by caspase-3. Science. 2010;330(6002):390-393.
16. Carroll RE, Benya RV, Turgeon DK, et al. Phase IIa clinical trial of curcumin for the prevention of colorectal neoplasia. Cancer Prev Res (Phila).2011;4(3):354-364.
17. Saha RN, Pahan K. Differential regulation of Mn-superoxide dismutase in neurons and astroglia by HIV-1 gp120: Implications for HIV-associated dementia. Free Radic Biol Med. 2007;42(12): 1866-1878.
18. Qi S N, Yoshida A, Ueda T. Activation of caspases-3/7 is dispensable for idarubicin-induced apoptotic DNA fragmentation in human leukemia cells. Int J Oncol. 2003;22(5):1123-1128.
19. Tyas L, Brophy VA, Pope A, et al. Rapid caspase-3 activation during apoptosis revealed using fluorescence-resonance energy transfer. EMBO Rep. 2000;1(3):266-270.
20. Castedo M, Perfettini JL, Andreau K, et al. Mitochondrial apoptosis induced by the HIV-1 envelope. Ann N Y Acad Sci. 2003;1010:19-28.
21. Garden GA, Budd SL, Tsai E, et al. Caspase cascades in human immunodeficiency virus-associated neurodegeneration. J Neurosci. 2002;22(10):4015-4024.
22. Yao H, Allen JE, Zhu X, et al. Cocaine and human immunodeficiency virus type 1 gp120 mediate neurotoxicity through overlapping signaling pathways. J Neurovirol. 2009;15(2): 164-175.
23. Friedlander RM, Gagliardini V, Hara H, et al. Expression of a dominant negative mutant of interleukin-1 beta converting enzyme in transgenic mice prevents neuronal cell death induced by trophic factor withdrawal and ischemic brain injury. J Exp Med. 1997;185(5):933-940.
24. Vicario-Abejon C. Long-term culture of hippocampal neurons. Curr Protoc Neurosci. 2004;Chapter 3:2-3.
25. Hoeck JD, Jandke A, Blake SM, et al. Fbw7 controls neural stem cell differentiation and progenitor apoptosis via Notch and c-Jun. Nat Neurosci. 2010;13(11):1365-1372.
26. Sims JT, Plattner R. MTT assays cannot be utilized to study the effects of STI571/Gleevec on the viability of solid tumor cell lines. Cancer Chemother Pharmacol. 2009;64(3):629-633.
27. Yin ST, Tang ML, Su L, et al. Effects of Epigallocatechin-3-gallate on lead-induced oxidative damage. Toxicology. 2008;249(1): 45-54.
28. Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T) Method. Methods. 2001;25(4):402-408.