Salmonella pathogenesis and processing of secreted effectors by caspase-3

Science

Volumn 330, Issue 6002, 2010, Pages 390-393

  Srikanth, C V ^a,b   Wall, Daniel M ^a,c   Maldonado Contreras, Ana ^b   Shi, Hai Ning ^a   Zhou, Daoguo ^d   Demma, Zachary ^b   Mumy, Karen L ^a,b   McCormick, Beth A ^a,b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF GLASGOW   (United Kingdom)

^d PURDUE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; BACTERIAL PROTEIN SIPA; CASPASE 3; UNCLASSIFIED DRUG; ACTIN BINDING PROTEIN; CASP3 PROTEIN, HUMAN; CASP3 PROTEIN, MOUSE; MUTANT PROTEIN; SIPA PROTEIN, SALMONELLA; VIRULENCE FACTOR;

BACTERIUM; ENZYME ACTIVITY; FOOD POISONING; GASTROENTERITIS; PATHOGEN; PATHOGENICITY; PROTEIN;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; GENE MUTATION; INTESTINE EPITHELIUM CELL; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN CLEAVAGE; SALMONELLA; SALMONELLOSIS; AMINO ACID SEQUENCE; ANIMAL; ANIMAL SALMONELLOSIS; CHEMISTRY; ENZYMOLOGY; GASTROENTERITIS; GENETICS; HUMAN; INTESTINE; INTESTINE MUCOSA; KNOCKOUT MOUSE; METABOLISM; MICROBIOLOGY; MOLECULAR GENETICS; MOUSE; NEUTROPHIL CHEMOTAXIS; PATHOGENICITY; PATHOLOGY; PROTEIN MOTIF; SALMONELLA ENTERICA SUBSP. ENTERICA SEROVAR TYPHIMURIUM; TUMOR CELL LINE;

BACTERIA (MICROORGANISMS); SALMONELLA; SALMONELLA ENTERICA SUBSP. ENTERICA SEROVAR TYPHIMURIUM; SALMONELLA TYPHIMURIUM;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; BACTERIAL PROTEINS; CASPASE 3; CELL LINE, TUMOR; ENZYME ACTIVATION; GASTROENTERITIS; HUMANS; INTESTINAL MUCOSA; INTESTINES; MICE; MICE, KNOCKOUT; MICROFILAMENT PROTEINS; MOLECULAR SEQUENCE DATA; MUTANT PROTEINS; NEUTROPHIL INFILTRATION; SALMONELLA INFECTIONS, ANIMAL; SALMONELLA TYPHIMURIUM; VIRULENCE FACTORS;

EID: 77957956726     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1194598     Document Type: Article

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25. The research was supported by grants from the NIH (DK56754 and DK33506) and the Crohn's and Colitis Foundation of America to B.A.M. Additional grant support was provided by Tenovus Scotland and a Society for General Microbiology travel award to D.M.W. The use of human volunteers in this study was in accordance with appropriate guidelines and was approved by the University of Massachusetts Medical School Review Board for the Protection of Human Subjects (approval no. 13006).