Neuroprotective labdane diterpenes from Fritillaria ebeiensis

Fitoterapia

Volumn 82, Issue 5, 2011, Pages 772-776

  Xu, Jing ^a   Liu, Cuizhou ^a   Guo, Ping ^a   Guo, Yuanqiang ^a   Jin, Da Qing ^a   Song, Xiaoqiang ^a   Sun, Zhanping ^a   Gui, Liping ^a   Ma, Yonggang ^a  

^a NANKAI UNIVERSITY   (China)

Author keywords

Diterpene; Fritillaria ebeiensis; Labdane; Neuroprotective effect

Indexed keywords

6 ALPHA,7 BETA DIHYDROXY LABDA 8 (17),12,14 TRIENE; 6 OXO 2 ALPHA HYDROXY LABDA 7,12,14 TRIENE; DITERPENE; LABDANE DITERPENE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DOPAMINERGIC ACTIVITY; DRUG ISOLATION; DRUG STRUCTURE; ELECTROSPRAY MASS SPECTROMETRY; FRITILLARIA; FRITILLARIA EBEIENSIS; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; INFRARED SPECTROSCOPY; NERVE CELL NECROSIS; NEUROBLASTOMA; NEUROPROTECTION; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL;

CELL DEATH; CELL LINE, TUMOR; DITERPENES; FRITILLARIA; HUMANS; NEUROPROTECTIVE AGENTS; PLANT EXTRACTS; PLANT ROOTS;

FRITILLARIA EBEIENSIS;

EID: 79957754157     PISSN: 0367326X     EISSN: 0367326X     Source Type: Journal    
DOI: 10.1016/j.fitote.2011.03.009     Document Type: Article

References (21)

1. Pieczenik SR, Neustadt J. Mitochondrial dysfunction and molecular pathways of disease. Exp Mol Pathol 2007;83:84.
2. Szeto HH. Mitochondria-targeted peptide antioxidants: novel neuroprotective agents. AAPS J 2006;8:521.
3. Eberhardt O, Schulz JB. Apoptotic mechanisms and antiapoptotic therapy in the MPTP model of Parkinson's disease. Toxicol Lett 2003;139:135.
4. Li P, Liu LN, Tan Y, Xu GJ. Studies on the constituents of Fritillaria ebeiensis. J China Pharm Univ 1994;25:7.
5. Akhtar MN, Rahman AU, Choudhary MI, Sener B, Erdogan I, Tsuda Y. New class of steroidal alkaloids from Fritillaria imperialis. Phytochemistry 2003;63:115.
6. Qian ZZ, Nohara T. Steroidal alkaloids of Fritillaria maximowiczii. Phytochemistry 1995;40:979.
7. Zhang JX, Lao AN, Xu RS. Steroidal alkaloids from Fritillaria thunbergii var. chekiangensis. Phytochemistry 1993;33:946.
8. Li P, Kitamura Y, Kaneko K, Shiro M, Xu GJ, Chen Y, et al. A steroidal alkaloid from Fritillaria ebeiensis. Phytochemistry 1992;31:2190.
9. Ori K, Mimaki Y, Sashida Y, Nikaido T, Ohmoto T. Steroidal alkaloids from the bulbs of Fritillaria persica. Phytochemistry 1992;31:4337.
10. Ori K, Mimaki Y, Sashida Y, Nikaido T, Ohmoto T. Cerveratrum alkaloids from bulbs of Fritillaria persica. Phytochemistry 1992;31:3605.
11. Shou QY, Tan Q, Shen ZW. A novel sulfur-containing diterpenoid from Fritillaria anhuiensis. Tetrahedron Lett 2009;50:4185.
12. Wu JZ, Morizane C, Iida A, Ueda S, Zhou ZL, Xu M, et al. Structures of three new diterpenoids, fritillebic acid and fritillebins A and B, from bulbs of Fritillaria ebeiensis. Chem Pharm Bull 1995;43:1448.
13. Sun HD, Huang SX, Han QB. Diterpenoids from Isodon species and their biological activities. Nat Prod Rep 2006;23:673.
14. Xu J, Jin D, Shi D, Ma Y, Yang B, Zhao P, et al. Sesquiterpenes from Vladimiria souliei and their inhibitory effects on NO production. Fitoterapia 2011;82:508.
15. Guo YQ, Li YS, Xu J, Watanabe RJ, Oshima Y, Yamakuni T, et al. Bioactive ent-clerodane diterpenoids from the aerial parts of Baccharis gaudichaudiana. J Nat Prod 2006;69:274.
16. Roengsumran S, Petsom A, Kuptiyanuwat N, Vilaivan T, Ngamrojnavanich N, Chaichantipyuth C, et al. Cytotoxic labdane diterpenoids from Croton oblongifolius. Phytochemistry 2001;56:103.
17. Sutthivaiyakit S, Nareeboon P, Ruangrangsi N, Ruchirawat S, Mahidol C. Labdane and pimarane diterpenes from Croton joufra. Phytochemistry 2001;56:811.
18. Gaspar-Marques C, Simões MF, Duarte A, Rodríguez B. Labdane and kaurane diterpenoids from Plectranthus fruticosus. J Nat Prod 2003;66:491.
19. Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 1983;65:55.
20. +/MPTP-induced cytotoxicity in vitro and in vivo. J Ethnopharmacol 2010;131:433.
21. +-induced cytotoxicity in neuroblastoma cells: antagonism and reversal by guanosine. Purinergic Signalling 2007;3:399.