Methyl-1-hydroxy-2-naphthoate, a novel naphthol derivative, inhibits lipopolysaccharide-induced inflammatory response in macrophages via suppression of NF-κB, JNK and p38 MAPK pathways

Inflammation Research

Volumn 60, Issue 9, 2011, Pages 851-859

  Zhang, Jun Yan ^a   Jin, Hong ^a   Wang, Guang Fa ^a   Yu, Peng Jiu ^a   Wu, Shao Yu ^a   Zhu, Zheng Guang ^a   Li, Zhong Huang ^a   Tian, Yuan Xin ^a   Xu, Wei ^a   Zhang, Jia Jie ^a   Wu, Shu Guang ^a  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

Author keywords

Inflammatory mediators; Macrophage; Methyl 1 hydroxy 2 naphthoate; Naphthol; NF B

Indexed keywords

1 NAPHTHOL DERIVATIVE; CYCLOOXYGENASE 2; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; INTERLEUKIN 6; JANUS KINASE; LIPOPOLYSACCHARIDE; MESSENGER RNA; METHYL 1 HYDROXY 2 NAPHTHOATE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; NITRIC OXIDE; PROSTAGLANDIN E2; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; DNA BINDING; DOSE RESPONSE; DRUG STRUCTURE; ENZYME ACTIVATION; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME PHOSPHORYLATION; ENZYME REPRESSION; GEL MOBILITY SHIFT ASSAY; INFLAMMATION; MACROPHAGE; NUCLEOTIDE SEQUENCE; PROTEIN DEGRADATION; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REPORTER GENE; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ANIMALS; CELL LINE; CYCLOOXYGENASE 2; HUMANS; I-KAPPA B PROTEINS; INFLAMMATION; INTERLEUKIN-1BETA; INTERLEUKIN-6; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; MOLECULAR STRUCTURE; NAPHTHOLS; NF-KAPPA B; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; P38 MITOGEN-ACTIVATED PROTEIN KINASES; SIGNAL TRANSDUCTION;

EID: 80052040989     PISSN: 10233830     EISSN: 1420908X     Source Type: Journal    
DOI: 10.1007/s00011-011-0345-2     Document Type: Article

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