메뉴 건너뛰기




Volumn 18, Issue 6, 2012, Pages 789-798

Apelin in the control of body fluid homeostasis and cardiovascular functions

Author keywords

Apelin; Brain; Cardiovascular system; Signaling; Vasopressin; Water balance

Indexed keywords

APELIN; APELIN RECEPTOR; VASOPRESSIN;

EID: 84863011829     PISSN: 13816128     EISSN: 18734286     Source Type: Journal    
DOI: 10.2174/138161212799277770     Document Type: Review
Times cited : (85)

References (86)
  • 1
    • 0027717002 scopus 로고
    • A human gene that shows identity with the gene encoding the angiotensin receptor is located on chromosome 11
    • O'Dowd BF, Heiber M, Chan A, et al. A human gene that shows identity with the gene encoding the angiotensin receptor is located on chromosome 11. Gene 1993; 136: 355-60.
    • (1993) Gene , vol.136 , pp. 355-360
    • O'Dowd, B.F.1    Heiber, M.2    Chan, A.3
  • 2
    • 0030273124 scopus 로고    scopus 로고
    • Expression of a new G protein-coupled receptor X-msr is associated with an endothelial lineage in Xenopus laevis
    • Devic E, Paquereau L, Vernier P, Knibiehler B, Audigier Y. Expression of a new G protein-coupled receptor X-msr is associated with an endothelial lineage in Xenopus laevis. Mech Dev 1996; 59: 129-40.
    • (1996) Mech Dev , vol.59 , pp. 129-140
    • Devic, E.1    Paquereau, L.2    Vernier, P.3    Knibiehler, B.4    Audigier, Y.5
  • 3
    • 0032811273 scopus 로고    scopus 로고
    • Amino acid sequence and embryonic expression of msr/apj, the mouse homolog of Xenopus X-msr and human APJ
    • Devic E, Rizzoti K, Bodin S, Knibiehler B, Audigier Y. Amino acid sequence and embryonic expression of msr/apj, the mouse homolog of Xenopus X-msr and human APJ. Mech Dev 1999; 84: 199-203.
    • (1999) Mech Dev , vol.84 , pp. 199-203
    • Devic, E.1    Rizzoti, K.2    Bodin, S.3    Knibiehler, B.4    Audigier, Y.5
  • 4
    • 0034517030 scopus 로고    scopus 로고
    • Cloning, pharmacological characterization and brain distribution of the rat apelin receptor
    • De Mota N, Lenkei Z, Llorens-Cortes C. Cloning, pharmacological characterization and brain distribution of the rat apelin receptor. Neuroendocrinology 2000; 72: 400-7.
    • (2000) Neuroendocrinology , vol.72 , pp. 400-407
    • de Mota, N.1    Lenkei, Z.2    Llorens-Cortes, C.3
  • 5
    • 0033985447 scopus 로고    scopus 로고
    • Characterization of apelin, the ligand for the APJ receptor
    • Lee DK, Cheng R, Nguyen T, et al. Characterization of apelin, the ligand for the APJ receptor. J Neurochem 2000; 74: 34-41.
    • (2000) J Neurochem , vol.74 , pp. 34-41
    • Lee, D.K.1    Cheng, R.2    Nguyen, T.3
  • 6
    • 0034697792 scopus 로고    scopus 로고
    • Distribution of mRNA encoding B78/apj, the rat homologue of the human APJ receptor, and its endogenous ligand apelin in brain and peripheral tissues
    • O'Carroll AM, Selby TL, Palkovits M, Lolait SJ. Distribution of mRNA encoding B78/apj, the rat homologue of the human APJ receptor, and its endogenous ligand apelin in brain and peripheral tissues. Biochim Biophys Acta 2000; 1492: 72-80.
    • (2000) Biochim Biophys Acta , vol.1492 , pp. 72-80
    • O'Carroll, A.M.1    Selby, T.L.2    Palkovits, M.3    Lolait, S.J.4
  • 7
    • 0032552988 scopus 로고    scopus 로고
    • Isolation and characterization of a novel endogenous peptide ligand for the human APJ receptor
    • Tatemoto K, Hosoya M, Habata Y, et al. Isolation and characterization of a novel endogenous peptide ligand for the human APJ receptor. Biochem Biophys Res Commun 1998; 251: 471-6.
    • (1998) Biochem Biophys Res Commun , vol.251 , pp. 471-476
    • Tatemoto, K.1    Hosoya, M.2    Habata, Y.3
  • 8
    • 0032826034 scopus 로고    scopus 로고
    • Apelin, the natural ligand of the orphan receptor APJ, is abundantly secreted in the colostrum
    • Habata Y, Fujii R, Hosoya M, et al. Apelin, the natural ligand of the orphan receptor APJ, is abundantly secreted in the colostrum. Biochim Biophys Acta 1999; 1452: 25-35.
    • (1999) Biochim Biophys Acta , vol.1452 , pp. 25-35
    • Habata, Y.1    Fujii, R.2    Hosoya, M.3
  • 9
    • 0034647520 scopus 로고    scopus 로고
    • Molecular and functional characteristics of APJ. Tissue distribution of mRNA and interaction with the endogenous ligand apelin
    • Hosoya M, Kawamata Y, Fukusumi S, et al. Molecular and functional characteristics of APJ. Tissue distribution of mRNA and interaction with the endogenous ligand apelin. J Biol Chem 2000; 275: 21061-7.
    • (2000) J Biol Chem , vol.275 , pp. 21061-21067
    • Hosoya, M.1    Kawamata, Y.2    Fukusumi, S.3
  • 10
    • 0035938189 scopus 로고    scopus 로고
    • Molecular properties of apelin: Tissue distribution and receptor binding
    • Kawamata Y, Habata Y, Fukusumi S, et al. Molecular properties of apelin: tissue distribution and receptor binding. Biochim Biophys Acta 2001; 1538: 162-71.
    • (2001) Biochim Biophys Acta , vol.1538 , pp. 162-171
    • Kawamata, Y.1    Habata, Y.2    Fukusumi, S.3
  • 11
    • 44049090382 scopus 로고    scopus 로고
    • Reciprocal regulation of plasma apelin and vasopressin by osmotic stimuli
    • Azizi M, Iturrioz X, Blanchard A, et al. Reciprocal regulation of plasma apelin and vasopressin by osmotic stimuli. J Am Soc Nephrol 2008; 19: 1015-24.
    • (2008) J Am Soc Nephrol , vol.19 , pp. 1015-1024
    • Azizi, M.1    Iturrioz, X.2    Blanchard, A.3
  • 12
    • 3142746678 scopus 로고    scopus 로고
    • Apelin, a potent diuretic neuropeptide counteracting vasopressin actions through inhibition of vasopressin neuron activity and vasopressin release
    • De Mota N, Reaux-Le Goazigo A, El Messari S, et al. Apelin, a potent diuretic neuropeptide counteracting vasopressin actions through inhibition of vasopressin neuron activity and vasopressin release. Proc Natl Acad Sci USA. 2004; 101: 10464-9.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 10464-10469
    • de Mota, N.1    Reaux-Legoazigo, A.2    el Messari, S.3
  • 13
    • 77952296548 scopus 로고    scopus 로고
    • Identification and pharmacological properties of E339-3D6, the first nonpeptidic apelin receptor agonist
    • Iturrioz X, Alvear-Perez R, De Mota N, et al. Identification and pharmacological properties of E339-3D6, the first nonpeptidic apelin receptor agonist. Faseb J 2010; 24: 1506-17.
    • (2010) Faseb J , vol.24 , pp. 1506-1517
    • Iturrioz, X.1    Alvear-Perez, R.2    de Mota, N.3
  • 14
    • 0037341188 scopus 로고    scopus 로고
    • Pharmacological and immunohistochemical characterization of the APJ receptor and its endogenous ligand apelin
    • Medhurst AD, Jennings CA, Robbins MJ, et al. Pharmacological and immunohistochemical characterization of the APJ receptor and its endogenous ligand apelin. J Neurochem 2003; 84: 1162-72.
    • (2003) J Neurochem , vol.84 , pp. 1162-1172
    • Medhurst, A.D.1    Jennings, C.A.2    Robbins, M.J.3
  • 15
    • 4544357878 scopus 로고    scopus 로고
    • Functional dissociation of apelin receptor signaling and endocytosis: Implications for the effects of apelin on arterial blood pressure
    • El Messari S, Iturrioz X, Fassot C, et al. Functional dissociation of apelin receptor signaling and endocytosis: implications for the effects of apelin on arterial blood pressure. J Neurochem 2004; 90: 1290-301.
    • (2004) J Neurochem , vol.90 , pp. 1290-1301
    • el Messari, S.1    Iturrioz, X.2    Fassot, C.3
  • 16
    • 18544378161 scopus 로고    scopus 로고
    • Hydrolysis of biological peptides by human angiotensin-converting enzyme-related carboxypeptidase
    • Vickers C, Hales P, Kaushik V, et al. Hydrolysis of biological peptides by human angiotensin-converting enzyme-related carboxypeptidase. J Biol Chem 2002; 277: 14838-43.
    • (2002) J Biol Chem , vol.277 , pp. 14838-14843
    • Vickers, C.1    Hales, P.2    Kaushik, V.3
  • 17
    • 42449150769 scopus 로고    scopus 로고
    • Apelin-13 induces ERK1/2 but not p38 MAPK activation through coupling of the human apelin receptor to the Gi2 pathway
    • Bai B, Tang J, Liu H, et al. Apelin-13 induces ERK1/2 but not p38 MAPK activation through coupling of the human apelin receptor to the Gi2 pathway. Acta Biochim Biophys Sin (Shanghai) 2008; 40: 311-8.
    • (2008) Acta Biochim Biophys Sin (Shanghai) , vol.40 , pp. 311-318
    • Bai, B.1    Tang, J.2    Liu, H.3
  • 18
    • 69249246993 scopus 로고    scopus 로고
    • G protein-coupled receptor APJ and its ligand apelin act downstream of Cripto to specify embryonic stem cells toward the cardiac lineage through extracellular signal-regulated kinase/p70S6 kinase signaling pathway
    • D'Aniello C, Lonardo E, Iaconis S, et al. G protein-coupled receptor APJ and its ligand apelin act downstream of Cripto to specify embryonic stem cells toward the cardiac lineage through extracellular signal-regulated kinase/p70S6 kinase signaling pathway. Circ Res 2009; 105: 231-8.
    • (2009) Circ Res , vol.105 , pp. 231-238
    • D'Aniello, C.1    Lonardo, E.2    Iaconis, S.3
  • 19
    • 54849424539 scopus 로고    scopus 로고
    • Apelin stimulates glucose utilization in normal and obese insulin-resistant mice
    • Dray C, Knauf C, Daviaud D, et al. Apelin stimulates glucose utilization in normal and obese insulin-resistant mice. Cell Metab 2008; 8: 437-45.
    • (2008) Cell Metab , vol.8 , pp. 437-445
    • Dray, C.1    Knauf, C.2    Daviaud, D.3
  • 20
    • 48649095013 scopus 로고    scopus 로고
    • Effect of apelin on glomerular hemodynamic function in the rat kidney
    • Hus-Citharel A, Bouby N, Frugiere A, et al. Effect of apelin on glomerular hemodynamic function in the rat kidney. Kidney Int 2008; 74: 486-94.
    • (2008) Kidney Int , vol.74 , pp. 486-494
    • Hus-Citharel, A.1    Bouby, N.2    Frugiere, A.3
  • 21
    • 42649135532 scopus 로고    scopus 로고
    • Apelin-induced vascular smooth muscle cell proliferation: The regulation of cyclin D1
    • Li F, Li L, Qin X, et al. Apelin-induced vascular smooth muscle cell proliferation: the regulation of cyclin D1. Front Biosci 2008; 13: 3786-92.
    • (2008) Front Biosci , vol.13 , pp. 3786-3792
    • Li, F.1    Li, L.2    Qin, X.3
  • 22
    • 77952993554 scopus 로고    scopus 로고
    • 14-3-3 mediates apelin-13-induced enhancement of adhesion of monocytes to human umbilical vein endothelial cells
    • Li X, Zhang X, Li F, et al. 14-3-3 mediates apelin-13-induced enhancement of adhesion of monocytes to human umbilical vein endothelial cells. Acta Biochim Biophys Sin (Shanghai) 2010; 42: 403-9.
    • (2010) Acta Biochim Biophys Sin (Shanghai) , vol.42 , pp. 403-409
    • Li, X.1    Zhang, X.2    Li, F.3
  • 23
    • 77952967421 scopus 로고    scopus 로고
    • PI3K/Akt signaling transduction pathway is involved in rat vascular smooth muscle cell proliferation induced by apelin-13
    • Liu C, Su T, Li F, et al. PI3K/Akt signaling transduction pathway is involved in rat vascular smooth muscle cell proliferation induced by apelin-13. Acta Biochim Biophys Sin (Shanghai) 2010; 42: 396-402.
    • (2010) Acta Biochim Biophys Sin (Shanghai) , vol.42 , pp. 396-402
    • Liu, C.1    Su, T.2    Li, F.3
  • 24
    • 0036289790 scopus 로고    scopus 로고
    • Apelin (65-77) activates extracellular signal-regulated kinases via a PTXsensitive G protein
    • Masri B, Lahlou H, Mazarguil H, Knibiehler B, Audigier Y. Apelin (65-77) activates extracellular signal-regulated kinases via a PTXsensitive G protein. Biochem Biophys Res Commun 2002; 290: 539-45.
    • (2002) Biochem Biophys Res Commun , vol.290 , pp. 539-545
    • Masri, B.1    Lahlou, H.2    Mazarguil, H.3    Knibiehler, B.4    Audigier, Y.5
  • 25
    • 10044296019 scopus 로고    scopus 로고
    • Apelin (65-77) activates p70 S6 kinase and is mitogenic for umbilical endothelial cells
    • Masri B, Morin N, Cornu M, Knibiehler B, Audigier Y. Apelin (65-77) activates p70 S6 kinase and is mitogenic for umbilical endothelial cells. Faseb J 2004; 18: 1909-11.
    • (2004) Faseb J , vol.18 , pp. 1909-1911
    • Masri, B.1    Morin, N.2    Cornu, M.3    Knibiehler, B.4    Audigier, Y.5
  • 26
    • 33745865147 scopus 로고    scopus 로고
    • The apelin receptor is coupled to Gi1 or Gi2 protein and is differentially desensitized by apelin fragments
    • Masri B, Morin N, Pedebernade L, Knibiehler B, Audigier Y. The apelin receptor is coupled to Gi1 or Gi2 protein and is differentially desensitized by apelin fragments. J Biol Chem 2006; 281: 18317-26.
    • (2006) J Biol Chem , vol.281 , pp. 18317-18326
    • Masri, B.1    Morin, N.2    Pedebernade, L.3    Knibiehler, B.4    Audigier, Y.5
  • 27
    • 0037032005 scopus 로고    scopus 로고
    • Apelin, the novel endogenous ligand of the orphan receptor APJ, regulates cardiac contractility
    • Szokodi I, Tavi P, Foldes G, et al. Apelin, the novel endogenous ligand of the orphan receptor APJ, regulates cardiac contractility. Circ Res 2002; 91: 434-40.
    • (2002) Circ Res , vol.91 , pp. 434-440
    • Szokodi, I.1    Tavi, P.2    Foldes, G.3
  • 28
    • 33846805814 scopus 로고    scopus 로고
    • Apelin stimulates proliferation and suppresses apoptosis of mouse osteoblastic cell line MC3T3- E1 via JNK and PI3-K/Akt signaling pathways
    • Tang SY, Xie H, Yuan LQ, et al. Apelin stimulates proliferation and suppresses apoptosis of mouse osteoblastic cell line MC3T3- E1 via JNK and PI3-K/Akt signaling pathways. Peptides 2007; 28: 708-18.
    • (2007) Peptides , vol.28 , pp. 708-718
    • Tang, S.Y.1    Xie, H.2    Yuan, L.Q.3
  • 29
    • 59249087073 scopus 로고    scopus 로고
    • Structural insight into G-protein coupled receptor binding by apelin
    • Langelaan DN, Bebbington EM, Reddy T, Rainey JK. Structural insight into G-protein coupled receptor binding by apelin. Biochemistry 2009; 48: 537-48.
    • (2009) Biochemistry , vol.48 , pp. 537-548
    • Langelaan, D.N.1    Bebbington, E.M.2    Reddy, T.3    Rainey, J.K.4
  • 30
    • 0034036766 scopus 로고    scopus 로고
    • Functional expression of the seven-transmembrane HIV-1 co-receptor APJ in neural cells
    • Choe W, Albright A, Sulcove J, et al. Functional expression of the seven-transmembrane HIV-1 co-receptor APJ in neural cells. J Neurovirol 2000; 6: S61-9.
    • (2000) J Neurovirol , vol.6
    • Choe, W.1    Albright, A.2    Sulcove, J.3
  • 31
    • 0344837395 scopus 로고    scopus 로고
    • Cell-cell fusion and internalization of the CNS-based, HIV-1 co-receptor, APJ
    • Zhou N, Fan X, Mukhtar M, et al. Cell-cell fusion and internalization of the CNS-based, HIV-1 co-receptor, APJ. Virology 2003; 307: 22-36.
    • (2003) Virology , vol.307 , pp. 22-36
    • Zhou, N.1    Fan, X.2    Mukhtar, M.3
  • 32
    • 0347627799 scopus 로고    scopus 로고
    • The N-terminal domain of APJ, a CNS-based coreceptor for HIV-1, is essential for its receptor function and coreceptor activity
    • Zhou N, Zhang X, Fan X, et al. The N-terminal domain of APJ, a CNS-based coreceptor for HIV-1, is essential for its receptor function and coreceptor activity. Virology 2003; 317: 84-94.
    • (2003) Virology , vol.317 , pp. 84-94
    • Zhou, N.1    Zhang, X.2    Fan, X.3
  • 33
    • 50949099615 scopus 로고    scopus 로고
    • Hypoxia-induced apelin expression regulates endothelial cell proliferation and regenerative angiogenesis
    • Eyries M, Siegfried G, Ciumas M, et al. Hypoxia-induced apelin expression regulates endothelial cell proliferation and regenerative angiogenesis. Circ Res 2008; 103: 432-40.
    • (2008) Circ Res , vol.103 , pp. 432-440
    • Eyries, M.1    Siegfried, G.2    Ciumas, M.3
  • 34
    • 2942711581 scopus 로고    scopus 로고
    • Regulatory roles for APJ, a seven-transmembrane receptor related to angiotensin-type 1 receptor in blood pressure in vivo
    • Ishida J, Hashimoto T, Hashimoto Y, et al. Regulatory roles for APJ, a seven-transmembrane receptor related to angiotensin-type 1 receptor in blood pressure in vivo. J Biol Chem 2004; 279: 26274-9.
    • (2004) J Biol Chem , vol.279 , pp. 26274-26279
    • Ishida, J.1    Hashimoto, T.2    Hashimoto, Y.3
  • 35
    • 50349086725 scopus 로고    scopus 로고
    • Vascular effects of apelin in vivo in man
    • Japp AG, Cruden NL, Amer DA, et al. Vascular effects of apelin in vivo in man. J Am Coll Cardiol 2008; 52: 908-13.
    • (2008) J Am Coll Cardiol , vol.52 , pp. 908-913
    • Japp, A.G.1    Cruden, N.L.2    Amer, D.A.3
  • 36
    • 34548696619 scopus 로고    scopus 로고
    • Apelin activates L-arginine/nitric oxide synthase/nitric oxide pathway in rat aortas
    • Jia YX, Lu ZF, Zhang J, et al. Apelin activates L-arginine/nitric oxide synthase/nitric oxide pathway in rat aortas. Peptides 2007; 28: 2023-9.
    • (2007) Peptides , vol.28 , pp. 2023-2029
    • Jia, Y.X.1    Lu, Z.F.2    Zhang, J.3
  • 37
    • 0035876612 scopus 로고    scopus 로고
    • The novel peptide apelin lowers blood pressure via a nitric oxide-dependent mechanism
    • Tatemoto K, Takayama K, Zou MX, et al. The novel peptide apelin lowers blood pressure via a nitric oxide-dependent mechanism. Regul Pept 2001; 99: 87-92.
    • (2001) Regul Pept , vol.99 , pp. 87-92
    • Tatemoto, K.1    Takayama, K.2    Zou, M.X.3
  • 38
    • 34247876193 scopus 로고    scopus 로고
    • Apelin modulates aortic vascular tone via endothelial nitric oxide synthase phosphorylation pathway in diabetic mice
    • Zhong JC, Yu XY, Huang Y, et al. Apelin modulates aortic vascular tone via endothelial nitric oxide synthase phosphorylation pathway in diabetic mice. Cardiovasc Res 2007; 74: 388-95.
    • (2007) Cardiovasc Res , vol.74 , pp. 388-395
    • Zhong, J.C.1    Yu, X.Y.2    Huang, Y.3
  • 39
    • 79961191336 scopus 로고    scopus 로고
    • Central Apelin Controls Glucose Homeostasis via a Nitric Oxide-Dependent Pathway in Mice
    • Duparc T, Colom A, Cani PD, et al. Central Apelin Controls Glucose Homeostasis via a Nitric Oxide-Dependent Pathway in Mice. Antioxid Redox Signal 2011; 15: 1477-96.
    • (2011) Antioxid Redox Signal , vol.15 , pp. 1477-1496
    • Duparc, T.1    Colom, A.2    Cani, P.D.3
  • 40
    • 0035015269 scopus 로고    scopus 로고
    • Physiological role of a novel neuropeptide, apelin, and its receptor in the rat brain
    • Reaux A, De Mota N, Skultetyova I, et al. Physiological role of a novel neuropeptide, apelin, and its receptor in the rat brain. J Neurochem 2001; 77: 1085-96.
    • (2001) J Neurochem , vol.77 , pp. 1085-1096
    • Reaux, A.1    de Mota, N.2    Skultetyova, I.3
  • 41
    • 77957815249 scopus 로고    scopus 로고
    • By interacting with the Cterminal Phe of apelin, Phe255 and Trp259 in helix VI of the apelin receptor are critical for internalization
    • Iturrioz X, Gerbier R, Leroux V, et al. By interacting with the Cterminal Phe of apelin, Phe255 and Trp259 in helix VI of the apelin receptor are critical for internalization. J Biol Chem 2010; 285: 32627-37.
    • (2010) J Biol Chem , vol.285 , pp. 32627-32637
    • Iturrioz, X.1    Gerbier, R.2    Leroux, V.3
  • 42
    • 11144240956 scopus 로고    scopus 로고
    • Modification of the terminal residue of apelin-13 antagonizes its hypotensive action
    • Lee DK, Saldivia VR, Nguyen T, et al. Modification of the terminal residue of apelin-13 antagonizes its hypotensive action. Endocrinology 2005; 146: 231-6.
    • (2005) Endocrinology , vol.146 , pp. 231-236
    • Lee, D.K.1    Saldivia, V.R.2    Nguyen, T.3
  • 43
    • 77951622241 scopus 로고    scopus 로고
    • The fate of the internalized apelin receptor is determined by different isoforms of apelin mediating differential interaction with beta-arrestin
    • Lee DK, Ferguson SS, George SR, O'Dowd BF. The fate of the internalized apelin receptor is determined by different isoforms of apelin mediating differential interaction with beta-arrestin. Biochem Biophys Res Commun 2010; 395: 185-9.
    • (2010) Biochem Biophys Res Commun , vol.395 , pp. 185-189
    • Lee, D.K.1    Ferguson, S.S.2    George, S.R.3    O'Dowd, B.F.4
  • 44
    • 0037008882 scopus 로고    scopus 로고
    • Distribution of apelin-synthesizing neurons in the adult rat brain
    • Reaux A, Gallatz K, Palkovits M, Llorens-Cortes C. Distribution of apelin-synthesizing neurons in the adult rat brain. Neuroscience 2002; 113: 653-62.
    • (2002) Neuroscience , vol.113 , pp. 653-662
    • Reaux, A.1    Gallatz, K.2    Palkovits, M.3    Llorens-Cortes, C.4
  • 45
    • 0037178686 scopus 로고    scopus 로고
    • Apelin-immunoreactivity in the rat hypothalamus and pituitary
    • Brailoiu GC, Dun SL, Yang J, et al. Apelin-immunoreactivity in the rat hypothalamus and pituitary. Neurosci Lett 2002; 327: 193-7.
    • (2002) Neurosci Lett , vol.327 , pp. 193-197
    • Brailoiu, G.C.1    Dun, S.L.2    Yang, J.3
  • 46
    • 4344590765 scopus 로고    scopus 로고
    • Dehydration-induced cross-regulation of apelin and vasopressin immunoreactivity levels in magnocellular hypothalamic neurons
    • Reaux-Le Goazigo A, Morinville A, Burlet A, Llorens-Cortes C, Beaudet A. Dehydration-induced cross-regulation of apelin and vasopressin immunoreactivity levels in magnocellular hypothalamic neurons. Endocrinology 2004; 145: 4392-400.
    • (2004) Endocrinology , vol.145 , pp. 4392-4400
    • Reaux-Le, G.A.1    Morinville, A.2    Burlet, A.3    Llorens-Cortes, C.4    Beaudet, A.5
  • 47
    • 80052496358 scopus 로고    scopus 로고
    • Data Supporting a New Physiological Role for Brain Apelin in the Regulation of Hypothalamic Oxytocin Neurons in Lactating Rats
    • Bodineau L, Taveau C, Le Quan Sang HH, et al. Data Supporting a New Physiological Role for Brain Apelin in the Regulation of Hypothalamic Oxytocin Neurons in Lactating Rats. Endocrinology 2011; 152: 3492-503.
    • (2011) Endocrinology , vol.152 , pp. 3492-3503
    • Bodineau, L.1    Taveau, C.2    Le Quan, S.H.H.3
  • 48
    • 0017644545 scopus 로고
    • Prevention of the development of renal hypertension by anteroventral third ventricular tissue lesions
    • Buggy J, Fink GD, Johnson AK, Brody MJ. Prevention of the development of renal hypertension by anteroventral third ventricular tissue lesions. Circ Res 1977; 40: I110-7.
    • (1977) Circ Res , vol.40
    • Buggy, J.1    Fink, G.D.2    Johnson, A.K.3    Brody, M.J.4
  • 49
    • 0030074678 scopus 로고    scopus 로고
    • Integrative role of the lamina terminalis in the regulation of cardiovascular and body fluid homeostasis
    • Johnson AK, Cunningham JT, Thunhorst RL. Integrative role of the lamina terminalis in the regulation of cardiovascular and body fluid homeostasis. Clin Exp Pharmacol Physiol 1996; 23: 183-91.
    • (1996) Clin Exp Pharmacol Physiol , vol.23 , pp. 183-191
    • Johnson, A.K.1    Cunningham, J.T.2    Thunhorst, R.L.3
  • 50
    • 0242468335 scopus 로고    scopus 로고
    • APJ receptor mRNA expression in the rat hypothalamic paraventricular nucleus: Regulation by stress and glucocorticoids
    • O'Carroll AM, Don AL, Lolait SJ. APJ receptor mRNA expression in the rat hypothalamic paraventricular nucleus: regulation by stress and glucocorticoids. J Neuroendocrinol 2003; 15: 1095-101.
    • (2003) J Neuroendocrinol , vol.15 , pp. 1095-1101
    • O'Carroll, A.M.1    Don, A.L.2    Lolait, S.J.3
  • 51
    • 85047680721 scopus 로고    scopus 로고
    • The V1a and V1b, but not V2, vasopressin receptor genes are expressed in the supraoptic nucleus of the rat hypothalamus, and the transcripts are essentially colocalized in the vasopressinergic magnocellular neurons
    • Hurbin A, Boissin-Agasse L, Orcel H, et al. The V1a and V1b, but not V2, vasopressin receptor genes are expressed in the supraoptic nucleus of the rat hypothalamus, and the transcripts are essentially colocalized in the vasopressinergic magnocellular neurons. Endocrinology 1998; 139: 4701-7.
    • (1998) Endocrinology , vol.139 , pp. 4701-4707
    • Hurbin, A.1    Boissin-Agasse, L.2    Orcel, H.3
  • 52
    • 1542300876 scopus 로고    scopus 로고
    • Immunocytochemical localization of the endogenous vasoactive peptide apelin to human vascular and endocardial endothelial cells
    • Kleinz MJ, Davenport AP. Immunocytochemical localization of the endogenous vasoactive peptide apelin to human vascular and endocardial endothelial cells. Regul Pept 2004; 118: 119-25.
    • (2004) Regul Pept , vol.118 , pp. 119-125
    • Kleinz, M.J.1    Davenport, A.P.2
  • 53
    • 0141615870 scopus 로고    scopus 로고
    • Novel role for the potent endogenous inotrope apelin in human cardiac dysfunction
    • Chen MM, Ashley EA, Deng DX, et al. Novel role for the potent endogenous inotrope apelin in human cardiac dysfunction. Circulation 2003; 108: 1432-9.
    • (2003) Circulation , vol.108 , pp. 1432-1439
    • Chen, M.M.1    Ashley, E.A.2    Deng, D.X.3
  • 54
    • 12344312427 scopus 로고    scopus 로고
    • Immunocytochemical localisation of the apelin receptor, APJ, to human cardiomyocytes, vascular smooth muscle and endothelial cells
    • Kleinz MJ, Skepper JN, Davenport AP. Immunocytochemical localisation of the apelin receptor, APJ, to human cardiomyocytes, vascular smooth muscle and endothelial cells. Regul Pept 2005; 126: 233-40.
    • (2005) Regul Pept , vol.126 , pp. 233-240
    • Kleinz, M.J.1    Skepper, J.N.2    Davenport, A.P.3
  • 55
    • 0035084443 scopus 로고    scopus 로고
    • [(125)I]-(Pyr(1))Apelin-13 is a novel radioligand for localizing the APJ orphan receptor in human and rat tissues with evidence for a vasoconstrictor role in man
    • Katugampola SD, Maguire JJ, Matthewson SR, Davenport AP. [(125)I]-(Pyr(1))Apelin-13 is a novel radioligand for localizing the APJ orphan receptor in human and rat tissues with evidence for a vasoconstrictor role in man. Br J Pharmacol 2001; 132: 1255-60.
    • (2001) Br J Pharmacol , vol.132 , pp. 1255-1260
    • Katugampola, S.D.1    Maguire, J.J.2    Matthewson, S.R.3    Davenport, A.P.4
  • 56
    • 0018900882 scopus 로고
    • Synthesis, transport, and release of posterior pituitary hormones
    • Brownstein MJ, Russell JT, Gainer H. Synthesis, transport, and release of posterior pituitary hormones. Science 1980; 207: 373-8.
    • (1980) Science , vol.207 , pp. 373-378
    • Brownstein, M.J.1    Russell, J.T.2    Gainer, H.3
  • 57
    • 0017687370 scopus 로고
    • Design of neurohypophyseal peptides that exhibit selective agonistic and antagonistic properties
    • Manning M, Lowbridge J, Haldar J, Sawyer WH. Design of neurohypophyseal peptides that exhibit selective agonistic and antagonistic properties. Fed Proc 1977; 36: 1848-52.
    • (1977) Fed Proc , vol.36 , pp. 1848-1852
    • Manning, M.1    Lowbridge, J.2    Haldar, J.3    Sawyer, W.H.4
  • 58
    • 0032032390 scopus 로고    scopus 로고
    • Vasopressin regularizes the phasic firing pattern of rat hypothalamic magnocellular vasopressin neurons
    • Gouzenes L, Desarmenien MG, Hussy N, Richard P, Moos FC. Vasopressin regularizes the phasic firing pattern of rat hypothalamic magnocellular vasopressin neurons. J Neurosci 1998; 18: 1879-85.
    • (1998) J Neurosci , vol.18 , pp. 1879-1885
    • Gouzenes, L.1    Desarmenien, M.G.2    Hussy, N.3    Richard, P.4    Moos, F.C.5
  • 59
    • 0031758058 scopus 로고    scopus 로고
    • Dendritic release of vasopressin and oxytocin
    • Ludwig M. Dendritic release of vasopressin and oxytocin. J Neuroendocrinol 1998; 10: 881-95.
    • (1998) J Neuroendocrinol , vol.10 , pp. 881-895
    • Ludwig, M.1
  • 60
    • 0017349344 scopus 로고
    • Electrophysiological differentiation of oxytocin- and vasopressin-secreting neurones
    • Poulain DA, Wakerley JB, Dyball RE. Electrophysiological differentiation of oxytocin-and vasopressin-secreting neurones. Proc R Soc Lond B Biol Sci 1977; 196: 367-84.
    • (1977) Proc R Soc Lond B Biol Sci , vol.196 , pp. 367-384
    • Poulain, D.A.1    Wakerley, J.B.2    Dyball, R.E.3
  • 61
    • 0035069755 scopus 로고    scopus 로고
    • The oxytocin receptor system: Structure, function, and regulation
    • Gimpl G, Fahrenholz F. The oxytocin receptor system: structure, function, and regulation. Physiol Rev 2001; 81: 629-83.
    • (2001) Physiol Rev , vol.81 , pp. 629-683
    • Gimpl, G.1    Fahrenholz, F.2
  • 62
    • 0022871457 scopus 로고
    • Regulation of vasopressin gene expression in rat hypothalamic neurons. Response to osmotic stimulation
    • Zingg HH, Lefebvre D, Almazan G. Regulation of vasopressin gene expression in rat hypothalamic neurons. Response to osmotic stimulation. J Biol Chem 1986; 261: 12956-9.
    • (1986) J Biol Chem , vol.261 , pp. 12956-12959
    • Zingg, H.H.1    Lefebvre, D.2    Almazan, G.3
  • 63
    • 0030772980 scopus 로고    scopus 로고
    • Vasopressin constricts outer medullary descending vasa recta isolated from rat kidneys
    • Turner MR, Pallone TL. Vasopressin constricts outer medullary descending vasa recta isolated from rat kidneys. Am J Physiol 1997; 272: F147-51.
    • (1997) Am J Physiol , vol.272
    • Turner, M.R.1    Pallone, T.L.2
  • 64
    • 70349330227 scopus 로고    scopus 로고
    • Abnormal fluid homeostasis in apelin receptor knockout mice
    • Roberts EM, Newson MJ, Pope GR, et al. Abnormal fluid homeostasis in apelin receptor knockout mice. J Endocrinol 2009; 202: 453-62.
    • (2009) J Endocrinol , vol.202 , pp. 453-462
    • Roberts, E.M.1    Newson, M.J.2    Pope, G.R.3
  • 65
    • 77952524790 scopus 로고    scopus 로고
    • Stimulus-specific neuroendocrine responses to osmotic challenges in apelin receptor knockout mice
    • Roberts EM, Pope GR, Newson MJ, et al. Stimulus-specific neuroendocrine responses to osmotic challenges in apelin receptor knockout mice. J Neuroendocrinol 2010; 22: 301-8.
    • (2010) J Neuroendocrinol , vol.22 , pp. 301-308
    • Roberts, E.M.1    Pope, G.R.2    Newson, M.J.3
  • 66
    • 79959396966 scopus 로고    scopus 로고
    • Hydration-sensitive Gene Expression in Brain
    • Tang C, Zelenak C, Volkl J, et al. Hydration-sensitive Gene Expression in Brain. Cell Physiol Biochem 2011; 27: 757-68.
    • (2011) Cell Physiol Biochem , vol.27 , pp. 757-768
    • Tang, C.1    Zelenak, C.2    Volkl, J.3
  • 67
    • 0037868944 scopus 로고    scopus 로고
    • Venous dilator effect of apelin, an endogenous peptide ligand for the orphan APJ receptor, in conscious rats
    • Cheng X, Cheng XS, Pang CC. Venous dilator effect of apelin, an endogenous peptide ligand for the orphan APJ receptor, in conscious rats. Eur J Pharmacol 2003; 470: 171-5.
    • (2003) Eur J Pharmacol , vol.470 , pp. 171-175
    • Cheng, X.1    Cheng, X.S.2    Pang, C.C.3
  • 68
    • 19944373052 scopus 로고    scopus 로고
    • The endogenous peptide apelin potently improves cardiac contractility and reduces cardiac loading in vivo
    • Ashley EA, Powers J, Chen M, et al. The endogenous peptide apelin potently improves cardiac contractility and reduces cardiac loading in vivo. Cardiovasc Res 2005; 65: 73-82.
    • (2005) Cardiovasc Res , vol.65 , pp. 73-82
    • Ashley, E.A.1    Powers, J.2    Chen, M.3
  • 69
    • 35648970003 scopus 로고    scopus 로고
    • Apelin effects in human splanchnic arteries. Role of nitric oxide and prostanoids
    • Salcedo A, Garijo J, Monge L, et al. Apelin effects in human splanchnic arteries. Role of nitric oxide and prostanoids. Regul Pept 2007; 144: 50-5.
    • (2007) Regul Pept , vol.144 , pp. 50-55
    • Salcedo, A.1    Garijo, J.2    Monge, L.3
  • 70
    • 70349245019 scopus 로고    scopus 로고
    • Davenport AP. [Pyr1]apelin-13 identified as the predominant apelin isoform in the human heart: Vasoactive mechanisms and inotropic action in disease
    • Maguire JJ, Kleinz MJ, Pitkin SL, Davenport AP. [Pyr1]apelin-13 identified as the predominant apelin isoform in the human heart: vasoactive mechanisms and inotropic action in disease. Hypertension 2009; 54: 598-604.
    • (2009) Hypertension , vol.54 , pp. 598-604
    • Maguire, J.J.1    Kleinz, M.J.2    Pitkin, S.L.3
  • 71
    • 4644320632 scopus 로고    scopus 로고
    • Apelin has in vivo inotropic effects on normal and failing hearts
    • Berry MF, Pirolli TJ, Jayasankar V, et al. Apelin has in vivo inotropic effects on normal and failing hearts. Circulation 2004; 110: II187-93.
    • (2004) Circulation , vol.110
    • Berry, M.F.1    Pirolli, T.J.2    Jayasankar, V.3
  • 72
    • 70350462121 scopus 로고    scopus 로고
    • Endogenous regulation of cardiovascular function by apelin-APJ
    • Charo DN, Ho M, Fajardo G, et al. Endogenous regulation of cardiovascular function by apelin-APJ. Am J Physiol Heart Circ Physiol 2009; 297: H1904-13.
    • (2009) Am J Physiol Heart Circ Physiol , vol.297
    • Charo, D.N.1    Ho, M.2    Fajardo, G.3
  • 73
    • 34547935393 scopus 로고    scopus 로고
    • Impaired heart contractility in Apelin gene-deficient mice associated with aging and pressure overload
    • Kuba K, Zhang L, Imai Y, et al. Impaired heart contractility in Apelin gene-deficient mice associated with aging and pressure overload. Circ Res 2007; 101: e32-42.
    • (2007) Circ Res , vol.101
    • Kuba, K.1    Zhang, L.2    Imai, Y.3
  • 74
    • 33751160364 scopus 로고    scopus 로고
    • Apelin increases contractility in failing cardiac muscle
    • Dai T, Ramirez-Correa G, Gao WD. Apelin increases contractility in failing cardiac muscle. Eur J Pharmacol 2006; 553: 222-8.
    • (2006) Eur J Pharmacol , vol.553 , pp. 222-228
    • Dai, T.1    Ramirez-Correa, G.2    Gao, W.D.3
  • 75
    • 49249099335 scopus 로고    scopus 로고
    • Apelin decreases the SR Ca2+ content but enhances the amplitude of [Ca2+]i transient and contractions during twitches in isolated rat cardiac myocytes
    • Wang C, Du JF, Wu F, Wang HC. Apelin decreases the SR Ca2+ content but enhances the amplitude of [Ca2+]i transient and contractions during twitches in isolated rat cardiac myocytes. Am J Physiol Heart Circ Physiol 2008; 294: H2540-6.
    • (2008) Am J Physiol Heart Circ Physiol , vol.294
    • Wang, C.1    Du, J.F.2    Wu, F.3    Wang, H.C.4
  • 76
    • 34248163595 scopus 로고    scopus 로고
    • Direct effects of apelin on cardiomyocyte contractility and electrophysiology
    • Farkasfalvi K, Stagg MA, Coppen SR, et al. Direct effects of apelin on cardiomyocyte contractility and electrophysiology. Biochem Biophys Res Commun 2007; 357: 889-95.
    • (2007) Biochem Biophys Res Commun , vol.357 , pp. 889-895
    • Farkasfalvi, K.1    Stagg, M.A.2    Coppen, S.R.3
  • 77
    • 0037376625 scopus 로고    scopus 로고
    • Regulatory effects of G protein-coupled receptors on cardiac sarcolemmal Na+/H+ exchanger activity: Signalling and significance
    • Avkiran M, Haworth RS. Regulatory effects of G protein-coupled receptors on cardiac sarcolemmal Na+/H+ exchanger activity: signalling and significance. Cardiovasc Res 2003; 57: 942-52.
    • (2003) Cardiovasc Res , vol.57 , pp. 942-952
    • Avkiran, M.1    Haworth, R.S.2
  • 78
    • 70349496049 scopus 로고    scopus 로고
    • Pulmonary apelin levels and effects in rats with hypoxic pulmonary hypertension
    • Andersen CU, Markvardsen LH, Hilberg O, Simonsen U. Pulmonary apelin levels and effects in rats with hypoxic pulmonary hypertension. Respir Med 2009; 103: 1663-71.
    • (2009) Respir Med , vol.103 , pp. 1663-1671
    • Andersen, C.U.1    Markvardsen, L.H.2    Hilberg, O.3    Simonsen, U.4
  • 79
    • 0033570229 scopus 로고    scopus 로고
    • A role for the sarcolemmal Na(+)/H(+) exchanger in the slow force response to myocardial stretch
    • Kentish JC. A role for the sarcolemmal Na(+)/H(+) exchanger in the slow force response to myocardial stretch. Circ Res 1999; 85: 658-60.
    • (1999) Circ Res , vol.85 , pp. 658-660
    • Kentish, J.C.1
  • 80
    • 33744816839 scopus 로고    scopus 로고
    • Plasma concentrations of the novel peptide apelin are decreased in patients with chronic heart failure
    • Chong KS, Gardner RS, Morton JJ, Ashley EA, McDonagh TA. Plasma concentrations of the novel peptide apelin are decreased in patients with chronic heart failure. Eur J Heart Fail 2006; 8: 355-60.
    • (2006) Eur J Heart Fail , vol.8 , pp. 355-360
    • Chong, K.S.1    Gardner, R.S.2    Morton, J.J.3    Ashley, E.A.4    McDonagh, T.A.5
  • 81
    • 0042165829 scopus 로고    scopus 로고
    • Circulating and cardiac levels of apelin, the novel ligand of the orphan receptor APJ, in patients with heart failure
    • Foldes G, Horkay F, Szokodi I, et al. Circulating and cardiac levels of apelin, the novel ligand of the orphan receptor APJ, in patients with heart failure. Biochem Biophys Res Commun 2003; 308: 480-5.
    • (2003) Biochem Biophys Res Commun , vol.308 , pp. 480-485
    • Foldes, G.1    Horkay, F.2    Szokodi, I.3
  • 82
    • 33847367028 scopus 로고    scopus 로고
    • Cardiac resynchronization therapy increases plasma levels of the endogenous inotrope apelin
    • Francia P, Salvati A, Balla C, et al. Cardiac resynchronization therapy increases plasma levels of the endogenous inotrope apelin. Eur J Heart Fail 2007; 9: 306-9.
    • (2007) Eur J Heart Fail , vol.9 , pp. 306-309
    • Francia, P.1    Salvati, A.2    Balla, C.3
  • 83
    • 33750301665 scopus 로고    scopus 로고
    • Down-regulation of cardiac apelin system in hypertrophied and failing hearts: Possible role of angiotensin II-angiotensin type 1 receptor system
    • Iwanaga Y, Kihara Y, Takenaka H, Kita T. Down-regulation of cardiac apelin system in hypertrophied and failing hearts: Possible role of angiotensin II-angiotensin type 1 receptor system. J Mol Cell Cardiol 2006; 41: 798-806.
    • (2006) J Mol Cell Cardiol , vol.41 , pp. 798-806
    • Iwanaga, Y.1    Kihara, Y.2    Takenaka, H.3    Kita, T.4
  • 84
    • 33947205566 scopus 로고    scopus 로고
    • Utility of plasma apelin and other indices of cardiac dysfunction in the clinical assessment of patients with dilated cardiomyopathy
    • Miettinen KH, Magga J, Vuolteenaho O, et al. Utility of plasma apelin and other indices of cardiac dysfunction in the clinical assessment of patients with dilated cardiomyopathy. Regul Pept 2007; 140: 178-84.
    • (2007) Regul Pept , vol.140 , pp. 178-184
    • Miettinen, K.H.1    Magga, J.2    Vuolteenaho, O.3
  • 85
    • 79952745361 scopus 로고    scopus 로고
    • Apelin protects against angiotensin II-induced cardiovascular fibrosis and decreases plasminogen activator inhibitor type-1 production
    • Siddiquee K, Hampton J, Khan S, et al. Apelin protects against angiotensin II-induced cardiovascular fibrosis and decreases plasminogen activator inhibitor type-1 production. J Hypertens 2011; 29: 724-31.
    • (2011) J Hypertens , vol.29 , pp. 724-731
    • Siddiquee, K.1    Hampton, J.2    Khan, S.3
  • 86
    • 77951768113 scopus 로고    scopus 로고
    • Acute Cardiovascular Effects of Apelin in Humans. Potential Role in Patients With Chronic Heart Failure
    • Japp AG, Cruden NL, Barnes G, et al. Acute Cardiovascular Effects of Apelin in Humans. Potential Role in Patients With Chronic Heart Failure. Circulation 2010; 121: 1818-27.
    • (2010) Circulation , vol.121 , pp. 1818-1827
    • Japp, A.G.1    Cruden, N.L.2    Barnes, G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.