G protein-coupled receptor APJ and its ligand apelin act downstream of cripto to specify embryonic stem cells toward the cardiac lineage through extracellular signal-regulated kinase/p70S6 kinase signaling pathway

Circulation Research

Volumn 105, Issue 3, 2009, Pages 231-238

  D'Aniello, Cristina ^a   Lonardo, Enza ^a   Iaconis, Salvatore ^a   Guardiola, Ombretta ^a   Liguoro, Anna Maria ^a   Liguori, Giovanna L ^a   Autiero, Monica ^b   Carmeliet, Peter ^b,c   Minchiotti, Gabriella ^a  

^a INSTITUTE OF GENETICS AND BIOPHYSICS ADRIANO BUZZATI TRAVERSO   (Italy)

^b DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^c UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

Apelin; APJ msr1; Cardiomyogenesis; Cripto; Embryonic stem cells

Indexed keywords

APELIN; APELIN RECEPTOR; G PROTEIN COUPLED RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PERTUSSIS TOXIN; SMAD2 PROTEIN; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; TRANSFORMING GROWTH FACTOR BETA RECEPTOR CRIPTO; UNCLASSIFIED DRUG; AGTRL1 PROTEIN, MOUSE; APLN PROTEIN, MOUSE; CARRIER PROTEIN; EPIDERMAL GROWTH FACTOR; MEMBRANE PROTEIN; S6 KINASE; SMAD2 PROTEIN, MOUSE; TDGF1 PROTEIN, MOUSE; TUMOR PROTEIN;

ANIMAL CELL; ARTICLE; CELL FATE; CONTROLLED STUDY; EMBRYO; EMBRYONIC STEM CELL; ENZYME ACTIVATION; GASTRULA; HEART MUSCLE CELL; MOUSE; MUSCLE DEVELOPMENT; NERVE CELL DIFFERENTIATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; ANIMAL; ANIMAL EMBRYO; CELL CULTURE; CELL DIFFERENTIATION; CELL LINE; CYTOLOGY; GENETICS; HEART MUSCLE; METABOLISM; MOUSE MUTANT; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; CARRIER PROTEINS; CELL DIFFERENTIATION; CELL LINE; CELLS, CULTURED; EMBRYO, MAMMALIAN; EMBRYONIC STEM CELLS; EPIDERMAL GROWTH FACTOR; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GTP-BINDING PROTEINS; MEMBRANE GLYCOPROTEINS; MICE; MICE, KNOCKOUT; MYOCARDIUM; MYOCYTES, CARDIAC; NEOPLASM PROTEINS; RECEPTORS, G-PROTEIN-COUPLED; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; SIGNAL TRANSDUCTION; SMAD2 PROTEIN;

EID: 69249246993     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.109.201186     Document Type: Article

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